Patents Assigned to INSTITUTE
  • Patent number: 9368316
    Abstract: Provided is an X-ray tube. The X-ray tube includes an electrode on which an electron beam impacts to generate an X-ray, and a window on which the electrode is disposed and through which the X-ray generated from the electrode is transmitted. The electrode includes a channel passing through the electrode, and the electron beam is provided into the channel to generate the X-ray.
    Type: Grant
    Filed: June 24, 2014
    Date of Patent: June 14, 2016
    Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Jin Woo Jeong, Yoon-Ho Song, Sungyoul Choi, Jun Tae Kang, Jae-woo Kim
  • Patent number: 9365496
    Abstract: Disclosed herein are ?-galactosylceramide (?-GalCer) analogs and compositions thereof, methods of activating invariant Natural Killer T (iNKT) cells using said analogs, methods of treating diseases by activating iNKT cells using said analogs, and combination therapy of said analogs.
    Type: Grant
    Filed: November 30, 2012
    Date of Patent: June 14, 2016
    Assignee: LUDWIG INSTITUTE FOR CANCER RESEARCH
    Inventors: Vincenzo Cerundolo, Gurdyal S. Besra, Liam Cox
  • Patent number: 9364503
    Abstract: Blood-derived plastic articles prepared from compositions including blood and, in some embodiments, at least one crosslinking agent and/or at least one biological response modifier, that can be useful for biological applications such as wound repair and tissue grafts; methods of making and using the same; methods for assessing the concentration of a biological response modifier in an article; and systems for preparing blood-derived plastic articles are provided.
    Type: Grant
    Filed: December 15, 2014
    Date of Patent: June 14, 2016
    Assignees: Carmell Therapeutics Corporation, Allegheny-Singer Research Institute, Carnegie Mellon University
    Inventors: Phil G. Campbell, James E. Burgess, Lee E. Weiss, Jason Smith
  • Patent number: 9366870
    Abstract: A display apparatus includes a planar waveguide optical element, a projection optical system, and a microdisplay device. By including free-form optics and waveguide technology, the volume and weight of the display apparatus can be reduced, and an optical system can be realized with improved image quality, structure, and performance parameters.
    Type: Grant
    Filed: June 3, 2015
    Date of Patent: June 14, 2016
    Assignee: BEIJING INSTITUTE OF TECHNOLOGY
    Inventors: Dewen Cheng, Yongtian Wang, Yue Liu
  • Patent number: 9367799
    Abstract: A computing device presents a cluster visualization based on a neural network computation. First centroid locations are computed for first clusters. Second centroid locations are computed for second clusters. Each centroid location includes a plurality of coordinate values where each coordinate value relates to a single variable of a plurality of variables. Distances are computed pairwise between each centroid location. An optimum pairing is selected based on a minimum distance of the computed pairwise distances where each pair is associated with a different cluster of a set of composite clusters. Noised centroid location data is created. A multi-layer neural network is trained with the noised centroid location data. A projected centroid location is determined in a multidimensional space for each centroid location as values of hidden units of a middle layer of the multi-layer neural network. A graph is presented for display that indicates the determined, projected centroid locations.
    Type: Grant
    Filed: October 28, 2015
    Date of Patent: June 14, 2016
    Assignee: SAS Institute Inc.
    Inventors: Patrick Hall, Ilknur Kaynar Kabul, Jared Langford Dean, Ralph Abbey, Susan Haller, Jorge Silva
  • Patent number: 9368336
    Abstract: An ion trap-based device and method for analyzing and detecting bipolar ions is provided. The device includes multiple electrodes of an ion trap; a radio frequency voltage source configured to form a radio frequency electric field; a direct current voltage source configured to form a bias electric field, positive and negative ions in the ion trap being separated by the bias electric field; a first and second detectors, configured to detect the positive and negative ions, respectively. A bipole and quadrupole field direct current voltage detection modes may be employed. A single positive ion or negative ion operation mode in a conventional biological mass spectrometry method is improved, so that the positive and negative ion modes are performed simultaneously; without any resolution loss, the analysis speed is increased, the sample consumption is reduced, and the accuracy of quantitative analysis of the samples is improved.
    Type: Grant
    Filed: January 31, 2013
    Date of Patent: June 14, 2016
    Assignee: Beijing Institute of Technology
    Inventors: Wei Xu, Muyi He, You Jiang, Zejian Huang, Xingchuang Xiong, Xiang Fang
  • Patent number: 9365498
    Abstract: The present invention relates to compounds of formula (I): or a pharmaceutically acceptable salt, hydrate, solvate, or prodrug thereof, wherein U, J, V, X, R2a, R2b, R2c, R5 and t are as described herein. The present invention relates generally to inhibitors of histone deacetylase and to methods of making and using them. These compounds are useful for promoting cognitive function and enhancing learning and memory formation. In addition, these compounds are useful for treating, alleviating, and/or preventing various conditions, including for example, neurological disorders, memory and cognitive function disorders/impairments, extinction learning disorders, fungal diseases and infections, inflammatory diseases, hematological diseases, and neoplastic diseases in humans and animals.
    Type: Grant
    Filed: October 28, 2013
    Date of Patent: June 14, 2016
    Assignees: The Broad Institute, Inc., The General Hospital Corporation, Massachusetts Institute of Technology
    Inventors: Edward Holson, Florence Fevrier Wagner, Michel Weiwer, Li-Huei Tsai, Stephen Haggarty, Yan-Ling Zhang
  • Patent number: 9365599
    Abstract: Novel N3S1 chelator-folate derivatives, a preparation method thereof, and a composition for diagnosis and treatment of tumor including the same as an active ingredient are provided. The novel N3S1 chelator-folate derivatives or a pharmaceutically acceptable salt thereof are easily introduced into the cells using receptor binding to tumor expressing ?-folate receptor (?-FR). Accordingly, the folate derivatives, labeled with radioisotope such as technetium, or rhenium, can be advantageously used for the diagnosis and treatment of tumor using tumor imaging and irradiation from the isotope, and therefore, can be widely used for the purpose of labeling a variety of radiopharmaceuticals.
    Type: Grant
    Filed: October 25, 2013
    Date of Patent: June 14, 2016
    Assignee: KOREA ATOMIC ENERGY RESEARCH INSTITUTE
    Inventors: Young-Don Hong, Sun Ju Choi, So-Young Lee, jae cheong Lim, Dong Eun Lee
  • Patent number: 9364933
    Abstract: The present invention relates to a jig for processing the inner surface of an aluminum alloy Winston cone baffle having the thickness of a sheet through an ultra-precision machining, the jig having a shape identically corresponding to the outer shape of a Winston cone baffle having a can body shape made up of compound parabolic, and divided into an upper plate jig and a lower plate jig in formation, wherein the upper plate jig is divided in two, a left side jig and a right side jig, which are formed to correspond in shape and size so as to enable isolation or coupling to/from each other, and the inner surface of the Winston cone baffle attached inside the upper plate jig is made to enable ultra-precision machining at the cutting speed of 220 m/min-300 m/min, which enables the inner surface of the Winston cone baffle to process a slickenside having approximately 4 nm of surface roughness, and in particular, ultra-precision machining at surface roughness of Ra=2.
    Type: Grant
    Filed: November 14, 2011
    Date of Patent: June 14, 2016
    Assignee: KOREA BASIC SCIENCE INSTITUTE
    Inventors: Sun Choel Yang, Ki Soo Chang, Geon Hee Kim, Myeong Sang Kim, Sang Yong Lee
  • Patent number: 9364514
    Abstract: A chimeric peptide construct having a cell penetrating peptide linked to a pro-apoptotic peptide. The construct can be used for treating a tumor in combination with an anti-tumor agent. Also disclosed is a method for treating a tumor with the chimeric peptide construct and a chemotherapeutic agent.
    Type: Grant
    Filed: December 27, 2012
    Date of Patent: June 14, 2016
    Assignees: Institute Curie, Universite Pierre et Marie Curie (Paris 6)
    Inventors: Angelita Rebollo Garcia, Fariba Nemati, Didier Decaudin
  • Patent number: 9367177
    Abstract: The present invention is to provide a method and system for determining true touch points on input touch panel. Two optical sensing module pairs are used to determine two groups of possible touch regions, further with overlap checking with virtual shadow regions to find out potential touch points. Occlusion checking is implemented to acquire true touch points from the potential touch points. The method of the present invention is capable of acquiring true touch points in a fast and reliable way. Furthermore, an interactive input system of the present invention comprises optical sensing modules having their corresponding optical emitters with different wavelengths, and light filters with peak transmission at different wavelengths to avoid from interference effect and over-exposed signal during signal detection by the optical sensing modules.
    Type: Grant
    Filed: June 27, 2013
    Date of Patent: June 14, 2016
    Assignee: Hong Kong Applied Science and Technology Research Institute Company Limited
    Inventors: Xiuling Zhu, Xurong Li, Lichun Ye
  • Patent number: 9366741
    Abstract: A medical diagnostic apparatus includes a data obtainer, which obtains an image frame included in a region to be imaged; and a data processor, which processes the obtained frame and obtains a medical image. The data obtainer includes a composite image generator, which generates a composite image by using the image frame; and a medical image obtainer, which compensates the composite image by using the image frame and boundary conditions corresponding to image signals included in the composite image and obtains the medical image by using the compensated composite image.
    Type: Grant
    Filed: June 18, 2013
    Date of Patent: June 14, 2016
    Assignees: SAMSUNG ELECTRONICS CO., LTD., KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Jae-moon Jo, Hyun-wook Park, Joon-sung Choi
  • Patent number: 9366667
    Abstract: The invention is directed to a isolated a Piscine reovirus associated with HSMI in teleosts, and isolated nucleic acids sequences and peptides thereof. The invention also relates to diagnostic antibodies against antigens derived from Piscine reoviruses. In another aspect, the invention relates to iRNAs which target nucleic acid sequences of Piscine reoviruses. In another aspect, the invention is related to methods for detecting the presence or absence of Piscine reoviruses in an animal.
    Type: Grant
    Filed: October 4, 2010
    Date of Patent: June 14, 2016
    Assignees: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE NATIONAL VETERINARY INSTITUTE
    Inventors: W. Ian Lipkin, Gustavo Palacios, Ruth Toril Kongtorp, Edgar Brun
  • Publication number: 20160158329
    Abstract: Compositions and methods for preventing, treating and detecting leishmaniasis are disclosed. The compositions generally comprise polypeptides comprising one or more Leishmania antigens as well as polynucleotides encoding such polypeptides.
    Type: Application
    Filed: March 28, 2014
    Publication date: June 9, 2016
    Applicant: Infectious Disease Research Institute
    Inventors: Jeff GUDERIAN, Malcolm DUTHIE, Steven G. REED
  • Publication number: 20160164007
    Abstract: Organic metal compounds, and organic light-emitting devices employing the same, are provided. The organic metal compound has a chemical structure represented by formula (I): wherein each R1 can be independently hydrogen, C1-12 alkyl group, C5-10 cycloalkyl group, C3-12 heteroaryl group, or C6-12 aryl group; R2 can be independently hydrogen, halogen, C1-12 alkyl group, C5-10 cycloalkyl group, C3-12 heteroaryl group, or C6-12 aryl group.
    Type: Application
    Filed: August 27, 2015
    Publication date: June 9, 2016
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Jin-Sheng LIN, Cheng-An WU, Pang-Chi HUANG, Meng-Hao CHANG, Han-Cheng YEH, Chun-Neng KU
  • Publication number: 20160164975
    Abstract: Disclosed is a method for mashing up heterogeneous sensors, which includes collecting an activity log from at least one sensor, converting the collected activity log into a common markup format, extracting an activity of a user from the activity log, based on an activity model which defines relations among activities, and outputting the extracted activity of the user in a semantic unit. Thus, it is possible to integrally utilize information of heterogeneous sensors, provide meaningful and intuitive information to a user, and share information of various applications and devices.
    Type: Application
    Filed: April 22, 2015
    Publication date: June 9, 2016
    Applicant: Korea Institute of Science and Technology
    Inventors: Daeil SEO, Byounghyun YOO, Heedong KO
  • Publication number: 20160158173
    Abstract: The treatment options for treating blast-induced and noise-induced traumatic brain injury and tinnitus are limited. Thus, the current invention provides methods for treating traumatic brain injury and tinnitus. The methods involve administering a pharmaceutically effective amount of a composition comprising 2,4-disulfonyl ?-phenyl tertiary butyl nitrone and N-acetylcysteine (NAC).
    Type: Application
    Filed: February 18, 2016
    Publication date: June 9, 2016
    Applicants: HOUGH EAR INSTITUTE, OKLAHOMA MEDICAL RESEARCH FOUNDATION
    Inventors: Richard D. KOPKE, Robert A. FLOYD, Rheal TOWNER
  • Publication number: 20160160052
    Abstract: Provided is a coating composition having anti-fogging and heat-insulating functions, which includes a mesoporous material, an organic polysiloxane, and co-doped tungsten oxide as shown in formula (I), MxWO3-yAy wherein M is an alkali metal element, W is tungsten, O is oxygen, A is halogen, 0<x?1, and 0<y?0.5. Further provided are a method for preparing a coating composition having anti-fogging and heat-insulating functions and a film formed from the coating composition.
    Type: Application
    Filed: December 24, 2014
    Publication date: June 9, 2016
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Yu-Yang Su, Pao-Tang Chung, Chun-Hsiang Wen, Chyi-Ming Leu, Sung-Jeng Jong
  • Publication number: 20160161249
    Abstract: In the present invention, conventional problems that the scheme is not suitable for nano/micro materials or large structures, and that if the scheme is applied to a regular pattern with two or more cycles of arbitrary repetition, a large error is generated are solved by using a higher order frequency of moire fringes generated using an arbitrary regular pattern having one-dimensional or two-dimensional repetition artificially produced on a surface of an object or previously present on the surface of the object, or phase information in a plurality of frequency components, and improvement of measurement precision and a dramatic increase in a limit of a measurement scale are achieved.
    Type: Application
    Filed: December 5, 2013
    Publication date: June 9, 2016
    Applicant: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY
    Inventors: Shien RI, Hiroshi TSUDA
  • Publication number: 20160163426
    Abstract: Provided is a method for manufacturing a conductive film. The method for manufacturing a conductive film includes providing a polymer thin-film on a base film, treating the polymer thin-film by using 10 M to 15 M of nitric acid, and washing the polymer thin-film treated with nitric acid. The nitric acid treatment is performed at room temperature for about 7 minutes to about 13 minutes.
    Type: Application
    Filed: December 2, 2015
    Publication date: June 9, 2016
    Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Sun Jin YUN, Changbong YEON