Patents Assigned to INSTITUTE
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Publication number: 20160168197Abstract: A novel compound of the formula (1): wherein X is a tyrosine residue or a methionine residue; Y and Z each are a single bond or the like; R1 is a hydrogen atom or the like; R2 is a hydroxy group or the like; R3 is a hydrogen atom, alkyl group, amino group or the like; R4 is a hydrogen atom, alkyl group, carboxy group or the like; m is 1 or 2; and n is an integer of 0 to 2, with the proviso that when n is 0, R3 is a hydrogen atom or an alkyl group, or a pharmaceutically acceptable salt thereof, and its use in cancer immunotherapy.Type: ApplicationFiled: February 26, 2016Publication date: June 16, 2016Applicants: International Institute of Cancer Immunology, Inc., Chugai Seiyaku Kabushiki Kaisha, Dainippon Sumitomo Pharma Co., Ltd.Inventors: Toshio NISHIHARA, Masashi Gotoh
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Publication number: 20160173310Abstract: Technologies are generally provided to enable the peak-to-average power ratio (PAPR) in OFDM communication systems to be adjusted to a particular level. In some examples, an N-symbol transmission vector may be partitioned into k equal partitions, a Fast Fourier Transform (FFT) may be performed on each partition, and an interleaving union of FFT results may be generated. The results of the interleaving union may be used for transmission after mapping them to the M subcarriers and performing an M-point IFFT. On the receiver side, FFT may be performed on M subcarriers, where each of L end user devices may be assigned N subcarriers out of M=N*L available subcarriers. The N subcarriers of the FFT results may be de-mapped and subjected to an interleaving partition. Subsequently, an Inverse FFT (IFFT) may be performed on each partition and results of the IFFT operation employed for symbol detection.Type: ApplicationFiled: November 16, 2013Publication date: June 16, 2016Applicant: Indian Institute of Technology DelhiInventors: Himanshu Nayar, Vinay Joseph Ribeiro, Ranjan Kumar Mallik
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Patent number: 9369512Abstract: A method and apparatus for an adaptive Hypertext Transfer Protocol (HTTP) streaming service using metadata of media content are provided. The media content may include a sequence of one or more periods. The metadata may include a start time attribute and/or a duration attribute of each of the periods. The metadata may determine a start time of each of the periods, and a start time of each of segments included in each of the periods. A terminal may access segments included in each of the periods, may decode and render data of media content included in the segments, and may play back the media content.Type: GrantFiled: April 8, 2014Date of Patent: June 14, 2016Assignees: Electronics and Telecommunications Research Institute, INDUSTRY-UNIVERSITY COOPERATION FOUNDATION KOREA AEROSPACE UNIVERSITYInventors: Truong Cong Thang, Jin Young Lee, Seong Jun Bae, Jung Won Kang, Soon Heung Jung, Sang Taick Park, Won Ryu, Jae Gon Kim
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Patent number: 9369086Abstract: Example embodiments are related to a high power spin torque oscillator that is integrated by combining a transistor. The high power spin torque oscillator according to example embodiments may include a spin torque oscillator and a transistor. The spin torque oscillator may perform an oscillation function and a transistor may perform an amplification function by integrating the spin torque oscillator and a transistor in one chip. The transistor may amplify an amplification signal of the spin torque oscillator. The high power spin torque oscillator may be integrated on FET or BJT.Type: GrantFiled: November 26, 2014Date of Patent: June 14, 2016Assignee: Korea Advanced Institute of Science and TechnologyInventors: Min Cheol Shin, Doo Hyung Kang, Jae Hyun Lee
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Patent number: 9365627Abstract: The invention provides compositions and methods for utilizing endomucin as an anti-inflammatory agent.Type: GrantFiled: August 6, 2012Date of Patent: June 14, 2016Assignee: The Schepens Eye Research Institute, Inc.Inventors: Patricia A. D'amore, Pablo Argüeso, Alisar S. Zahr
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Patent number: 9366558Abstract: Heteronuclear radioisotope nanoparticle of core-shell structure and a preparation method thereof are provided. The Heteronuclear radioisotope nanoparticle of core-shell structure comprising core of two different radioisotopes selected from a group consisting of 198Au, 63Ni, 110mAg, 64Cu, 60Co, 192Ir and 103Pd, and a shell comprising SiO2 surrounding the core. The Heteronuclear radioisotope nanoparticle of core-shell can be used as a tracer for the purpose of detecting variation of volume ratio or for the evaluation of the behavior characteristic of a water resource, based on information about phase ratio in the flow of multiphase fluid existing in a process which is operated under extreme condition such as high temperature and/or high pressure conditions.Type: GrantFiled: April 8, 2015Date of Patent: June 14, 2016Assignee: Korea Atomic Energy Research InstituteInventors: Sung-Hee Jung, Seong-Ho Choi, Jong-bum Kim, Jinho Moon, Jin-Hyuck Jung
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Patent number: 9368475Abstract: A manufacturing method of a semiconductor device is provided. First, a mould is provided. The mould has a chamber, patterns in the chamber, and protrusions in the chamber. A carrier substrate having at least one die located thereon is disposed in the chamber, and the protrusions surround the die. A thermosetting material is injected into the chamber and is cured. The cured thermosetting material is separated from the mould, so as to form an interposer substrate. A plurality of through holes corresponding to the protrusions and a plurality of grooves corresponding to the patterns are formed on the interposer substrate. A conductive material is filled into the through holes and the grooves to form a plurality of conductive pillars and a first conductive pattern layer on a first surface of the interposer substrate. The first conductive pattern layer is electrically connected with the conductive pillars.Type: GrantFiled: June 25, 2015Date of Patent: June 14, 2016Assignee: Industrial Technology Research InstituteInventors: Shang-Chun Chen, Cha-Hsin Lin, Tzu-Kun Ku
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Patent number: 9365866Abstract: A reprogramming gene-loaded Sendai viral vector comprising Sendai virus genes and reprogramming genes, wherein the Sendai virus genes include an NP gene, P/C gene, M gene, F gene, HN gene and L gene, wherein each of the M gene, the F gene and the FIN gene is from a Sendai virus strain Cl.151-derived gene and wherein at least one of the M gene, the F gene and the HN gene is functionally deleted and the L gene encodes the amino-acid sequence of the L protein in which the amino-acid residue at position 1618 is valine and a method of producing the same.Type: GrantFiled: November 9, 2011Date of Patent: June 14, 2016Assignee: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGYInventors: Mahito Nakanishi, Ken Nishimura, Masayuki Sano, Manami Ohtaka
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Patent number: 9364033Abstract: A shock-absorbing device for a human body which can reduce an impact applied to the human body when a wearer falls is provided.Type: GrantFiled: February 22, 2012Date of Patent: June 14, 2016Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGYInventor: Choong-Hyun Kim
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Patent number: 9364532Abstract: The present disclosure concerns an oncolytic virus for the treatment of cancer, such as in brain cancer, for example glioblastoma. The oncolytic virus may exhibit reduced levels of neurotoxicity. The oncolytic virus may be an isolated viral particle capable of producing a cDNA polynucleotide that includes a sequence according to SEQ ID NO: 1 when the virus is in a host cell. The oncolytic virus may be an isolated viral particle that includes an RNA polynucleotide that includes a sequence according to SEQ ID NO: 2. The oncolytic virus may be an isolated viral particle having a genome that includes open reading frames that encode: proteins having sequences comprising SEQ ID NOs: 3, 4, 5, 6 and 7; or variants thereof.Type: GrantFiled: June 7, 2012Date of Patent: June 14, 2016Assignee: CHILDREN'S HOSPITAL OF EASTERN ONTARIO RESEARCH INSTITUTE INC.Inventor: David F. Stojdl
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Patent number: 9365528Abstract: Derivatives of sulindac that lack cyclooxygenase inhibitory activity are provided along with pharmaceutical compositions containing them and use for treatment or prevention of cancer. The derivatives of sulindac are also suitable for treating chronic inflammatory conditions. A method for preparing the derivatives is also provided.Type: GrantFiled: March 30, 2012Date of Patent: June 14, 2016Assignee: Southern Research InstituteInventors: Robert Reynolds, Bini Mathew, Gary A. Piazza
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Patent number: 9369434Abstract: A whitelist-based network switch defines a whitelist and a handling rule based on an access control list, security policies, etc., and monitors and blocks network traffic based on the whitelist and the handling rule. The whitelist-based network switch includes a whitelist monitoring unit for storing a whitelist including permitted communication rules, monitoring one or more packets input through a plurality of switch interfaces based on the whitelist, and permitting communication of each packet conforming to the whitelist, and a whitelist management unit for updating the whitelist and transmitting an updated whitelist to the whitelist monitoring unit.Type: GrantFiled: July 14, 2014Date of Patent: June 14, 2016Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTEInventors: Heemin Kim, Jeong-Han Yun, Kyoung-Ho Kim, Woonyon Kim, Jungtaek Seo, Chun soo Kim
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Patent number: 9368287Abstract: A dye-sensitized solar cell having improved photoelectric conversion characteristic includes a metal oxide layer having dye-adsorbed metal oxide nanoparticles, wherein the metal oxide nanoparticles are formed by electrospinning a mixed solution of a metal oxide precursor and a polymer into ultrafine composite fibers, and thermally compressing and sintering the ultrafine composite fibers.Type: GrantFiled: August 27, 2008Date of Patent: June 14, 2016Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Seong-Mu Jo, Dong-Young Kim, Sung-Yeon Jang, Nam-Gyu Park, Byoung-Hong Yi
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Patent number: 9367805Abstract: Systems, methods, and computer-readable media for generating a data set are provided. One method includes generating a data set based on input data using a plurality of brokers. The method further includes receiving a request from a user and determining whether the request can be fulfilled using data currently in the data set. When the request can be fulfilled using data currently in the data set, the data is accessed using broker(s) configured to provide access to data within the data set. When the request cannot be fulfilled using data currently in the data set, at least one new broker is spawned using existing broker(s) and additional data needed to fulfill the request is added to the data set using the new broker. The method further includes generating a response to the request using one or more of the plurality of brokers.Type: GrantFiled: March 9, 2015Date of Patent: June 14, 2016Assignee: Virginia Polytechnic Institute and State UniversityInventors: Christopher L. Barrett, Madhav V. Marathe, Keith R. Bisset
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Patent number: 9367585Abstract: A data storage and query method supporting an agile development and horizontal scaling, in a field of computer applications, includes steps of: transforming data into a 2-tuple (Key, MiniTable) and identifying any MiniTable (having a data set removed) with a unique Key, wherein the MiniTable includes multiple data columns; a structure of each data column is limited by a pre-defined mode; and the data columns are sorted according to a primary key defined by the mode. The data storage and query method obtains a capability of the horizontal scaling via removing dependency among the data sets, and a capability of the agile development via supporting an analogous SQL grammar by saving dependency among the data within the data sets. The data storage and query method can be applied to a data management system which supports the horizontal scaling of big data and the agile development of short development lifecycles.Type: GrantFiled: April 18, 2012Date of Patent: June 14, 2016Assignee: GUANGDONG ELECTRONICS INDUSTRY INSTITUTE LTD.Inventors: Lei Nie, Zhiwei Xu, Guojie Li, Jingjie Liu, Qiang Yue
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Patent number: 9364157Abstract: An apparatus and method based on image for detecting heart rate activity is provided. The method includes: obtaining a plurality of color images; based on a complexion target condition, defining a target region; performing color composition analysis on the target region to obtain red channel signal, green channel signal and blue channel signal, respectively; performing independent component analysis on separate red, green and blue channel signals to obtain separate first independent component signal, second independent component signal and third independent component signal; performing frequency domain transform, signal energy computation and signal optimization processes on separate first, second and third independent component signals to obtain a filter signal, comparing filter signal based on a pre-set condition to determine if target region belonging to a human, and performing a physiological information analysis.Type: GrantFiled: April 2, 2014Date of Patent: June 14, 2016Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Tung-Hung Lu, Hui-Chen Ku, Rong-Rong Chen
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Patent number: 9368271Abstract: First and second paths of the primary-coil of the transformer are located at different sides of the symmetry-line. First terminals of the first and second paths are first and second ports of the primary-coil. Second terminals of the first and second paths are connected to each other. Two partial paths of the first path are connected to each other by TSV. Two partial paths of the second path are connected to each other by TSV. Third and fourth paths of the secondary-coil of the transformer are located on different sides of the symmetry-line. First terminals of the third and fourth paths are first and second ports of the secondary-coil. Second terminals of the third and fourth paths are connected to each other. Two partial paths of the third path are connected to each other by TSV. Two partial paths of the fourth path are connected to each other by TSV.Type: GrantFiled: April 22, 2015Date of Patent: June 14, 2016Assignee: Industrial Technology Research InstituteInventors: Sih-Han Li, Chih-Sheng Lin
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Patent number: 9366638Abstract: A method and system for generating a clarity grading look-up table includes collecting actual inclusion parameter data for a plurality of gems, where the actual inclusion parameter data includes an actual clarity grade and an actual inclusion parameter data combination. A mathematical relationship between a clarity grade and a particular inclusion parameter combination is then extrapolated from the actual inclusion parameter data. A derived clarity grade is then assigned to a plurality of inclusion parameter combinations as a function of the mathematical relationship and a set of inputted inclusion parameters. Also, a method and system for providing a clarity grade includes receiving a plurality of inclusion characteristics associated with a gem and parameterizing each of the inclusion characteristics, so that a parameter value is assigned to each inclusion characteristic. The parameter values are then input to a mathematical formula so as to provide a parameterized clarity grade for the gem.Type: GrantFiled: March 18, 2013Date of Patent: June 14, 2016Assignee: GEMOLOGICAL INSTITUTE OF AMERICA, INC. (GIA)Inventors: Marc Verboven, Troy Blodgett
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Patent number: 9367610Abstract: Systems and methods are disclosed that provide high-level, ontology-based analysis of low-level data stored within an unstructured key/value store. The systems and methods allow an analyst to make sense of massive amounts of data from diverse sources without having any knowledge of the underlying physical data storage. Additional features include feasibility queries to determine if requested data exists in the key/value store before performing an expensive query; automatic query optimization using secondary indexes; and a usage history service to identify performance bottlenecks and fine tune the storage schema.Type: GrantFiled: January 16, 2014Date of Patent: June 14, 2016Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGYInventors: Suresh K. Damodaran, Benjamin D. O'Gwynn, Tamara H. Yu
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Patent number: 9368824Abstract: Iron-sulfide redox flow battery (RFB) systems can be advantageous for energy storage, particularly when the electrolytes have pH values greater than 6. Such systems can exhibit excellent energy conversion efficiency and stability and can utilize low-cost materials that are relatively safer and more environmentally friendly. One example of an iron-sulfide RFB is characterized by a positive electrolyte that comprises Fe(III) and/or Fe(II) in a positive electrolyte supporting solution, a negative electrolyte that comprises S2? and/or S in a negative electrolyte supporting solution, and a membrane, or a separator, that separates the positive electrolyte and electrode from the negative electrolyte and electrode.Type: GrantFiled: November 13, 2013Date of Patent: June 14, 2016Assignee: Battelle Memorial InstituteInventors: Guanguang Xia, Zhenguo Yang, Liyu Li, Soowhan Kim, Jun Liu, Gordon L Graff