Patents Assigned to INSTITUTE
  • Patent number: 12275941
    Abstract: RNA interference-based methods and products for inhibiting the expression of pathogenic dynamin-1 variants are provided. Delivery vehicles such as recombinant adeno-associated viruses deliver DNAs encoding RNAs that inhibit the expression of the dynamin-1 variants. The methods treat, for example, developmental and epileptic encephalopathies.
    Type: Grant
    Filed: April 15, 2021
    Date of Patent: April 15, 2025
    Assignees: RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL, THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: Scott Quenton Harper, Wayne N. Frankel
  • Patent number: 12276037
    Abstract: An anodized titanium material includes a titanium base material and an anodized titanium layer. The anodized titanium layer is provided on a surface of the titanium base material. The anodized titanium layer includes a porous first anodized titanium layer. The anodized titanium layer has a withstand voltage at 25° C. of 500 V or more, a Vickers hardness of 200 or more, a film thickness of 20 ?m or more and less than 80 ?m, an arithmetic average roughness Ra of a surface of less than 1.6 ?m, and a maximum height roughness Rz of the surface is less than 6.3 ?m. In both of a section perpendicular to a thickness direction of the first anodized titanium oxide layer and the surface, no pore sections having a shape capable of including a circle having a diameter of 0.5 ?m or more are observed.
    Type: Grant
    Filed: February 8, 2021
    Date of Patent: April 15, 2025
    Assignees: YAMAGUCHI PREFECTURAL INDUSTRIAL TECHNOLOGY INSTITUTE, SANWA INDUSTRY CO., LTD., TOKYO ELECTRON LIMITED
    Inventors: Takehiko Muranaka, Kouji Niimi, Yuuta Ueno, Hikaru Kikuchi, Hideto Saito, Nobuyuki Nagayama
  • Patent number: 12278393
    Abstract: Separator systems for electrochemical systems providing electronic, mechanical and chemical properties useful for a variety of applications including electrochemical storage and conversion. Embodiments provide structural, physical and electrostatic attributes useful for managing and controlling dendrite formation and for improving the cycle life and rate capability of electrochemical cells including silicon anode based batteries, air cathode based batteries, redox flow batteries, solid electrolyte based systems, fuel cells, flow batteries and semisolid batteries.
    Type: Grant
    Filed: October 28, 2022
    Date of Patent: April 15, 2025
    Assignee: California Institute of Technology
    Inventor: Farshid Roumi
  • Patent number: 12276667
    Abstract: Disclosed herein are methods for solubilizing and isolating nuclear proteins from cells.
    Type: Grant
    Filed: May 21, 2019
    Date of Patent: April 15, 2025
    Assignee: Altius Institute for Biomedical Sciences
    Inventors: Alexander Federation, John Stamatoyannopoulos
  • Patent number: 12279534
    Abstract: According to one embodiment, a spin injection source comprising a half Heusler alloy-topological semi-metal that has a surface state of Dirac type and that is in contact with a ferromagnet. The half Heusler alloy-topological semi-metal supplies a spin current to the ferromagnet based on a current flowing in a direction parallel to a first surface that is in contact with the ferromagnet.
    Type: Grant
    Filed: August 24, 2022
    Date of Patent: April 15, 2025
    Assignee: INSTITUTE OF SCIENCE TOKYO
    Inventors: Nam Hai Pham, Takanori Shirakura, Tsuyoshi Kondo
  • Patent number: 12275749
    Abstract: A rotaxane compound comprising one or more cyclic molecules and an axial molecule penetrating through inner holes of the cyclic molecules and having cap structures disposed lest the cyclic molecules should be detached, where one of the cyclic molecule and the axial molecule has one of a functional group being capable of reacting with silica and a functional group being capable of reacting with a carbon-carbon unsaturated bond, and the other of the cyclic molecule and the axial molecule has the other of the functional group being capable of reacting with silica and the functional group being capable of reacting with a carbon-carbon unsaturated bond.
    Type: Grant
    Filed: April 25, 2019
    Date of Patent: April 15, 2025
    Assignees: SUMITOMO RUBBER INDUSTRIES, LTD., TOKYO INSTITUTE OF TECHNOLOGY
    Inventors: Shoko Nakahata, Toshikazu Takata, Toyokazu Tsutsuba
  • Patent number: 12277996
    Abstract: Disclosed herein is an apparatus for hardware metering using a memory-type camouflaged cell. The apparatus includes memory including at least one camouflaged memory cell in which a key is hidden by a designer in advance and a controller for controlling whether to block the supply of power to the memory. The controller may perform reading a key from a corresponding key location in the multiple memory cells of the memory based on key location information stored in the controller when a key is input from the outside, determining whether the key input from the outside is the same as the key read from the memory, setting an authentic flag based on the determination result, and performing control based on the set authentic flag such that the memory operates normally or the supply of power is blocked.
    Type: Grant
    Filed: February 5, 2024
    Date of Patent: April 15, 2025
    Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventor: Jae-Mun Oh
  • Patent number: 12275653
    Abstract: Provided are a system for monitoring a hydroxyl radical scavenging index in water using a real-time multi-fluorescence analyzer and a parallel factor analysis apparatus and a method therefor, wherein the system monitors the hydroxyl radical scavenging index in water using the real-time multi-fluorescence analyzer and the parallel factor analysis apparatus, whereby it is possible to monitor the characteristics of an organic material in target water through a continuous flow analysis method without using an existing indicator material, rhodamine B.
    Type: Grant
    Filed: November 19, 2020
    Date of Patent: April 15, 2025
    Assignee: KOREA INSTITUTE OF CIVIL ENGINEERING AND BUILDING TECHNOLOGY
    Inventors: Tae Mun Hwang, Sook Hyun Nam, Eun-Ju Kim, Jae-Wuk Koo
  • Patent number: 12278020
    Abstract: The present disclosure discloses a supporting insulation base of a negative high-voltage potential neutron target of a compact neutron source, including a cylindrical coolant liquid channel, a cylindrical high-voltage channel, an upper cover plate and a lower cover plate, which are integrally formed by 3D printing using a PEEK material.
    Type: Grant
    Filed: October 25, 2024
    Date of Patent: April 15, 2025
    Assignee: Institute of Energy, Hefei Comprehensive National Science Center (Anhui Energy Laboratory)
    Inventors: Xiancai Meng, Xu Li, Lizhen Liang, Yuzhong Qian, Bing Hong
  • Patent number: 12275135
    Abstract: A humanoid finger mechanism includes: a finger seat; at least one proximal knuckle, located at an outer side of the finger seat; at least one middle knuckle, located at an outer side of the at least one proximal knuckle; a distal knuckle, located at an outer side of the at least one middle knuckle; a driver, located at an inner side of the finger seat; a driving cable, wherein a first end of the driving cable is connected with the driver, while a second end of the driving cable is connected with the distal knuckle after sequentially penetrating through the finger seat, the at least one proximal knuckle and the at least one middle knuckle; and a tension band, a first end of the tension band is connected with the finger seat, while a second end of the tension band is connected with the distal knuckle.
    Type: Grant
    Filed: November 29, 2021
    Date of Patent: April 15, 2025
    Assignee: CHANGZHOU INSTITUTE OF TECHNOLOGY
    Inventors: Hongliang Hua, Shihong Wu, Xiaofeng Wu, Yongjiang Chen, Xiaojun Wang, Cheng Huang
  • Patent number: 12278104
    Abstract: The present disclosure relates to the technical field of semiconductors. Disclosed is a multi-layer semiconductor material structure and a preparation method thereof, solving the problems of the existing semiconductor materials that have poor heat dissipation, high cost, and cannot be mass-produced. The multi-layer semiconductor material structure includes a highly thermally conductive support substrate and a crystallized device function layer, where the device function layer is provided on the highly thermally conductive support substrate, and has a single-crystal surface layer.
    Type: Grant
    Filed: September 9, 2021
    Date of Patent: April 15, 2025
    Assignee: Institute of Microelectronics of the Chines Academy of Sciences
    Inventors: Fengwen Mu, Xinhua Wang, Sen Huang, Ke Wei, Xinyu Liu
  • Patent number: 12276639
    Abstract: A large-space high-temperature and high-pressure true triaxial flexible loading device includes a cylinder reaction frame, which includes a cylinder, a lower shear ring, an upper shear ring, a bottom cover, and a top cover, wherein the bottom cover and the top cover are detachably mounted at a bottom and a top inside the cylinder respectively, and an interior of the cylinder is divided to form a loading space for performing a triaxial test on a square test block; the lower shear ring is detachably embedded on an inner wall of the cylinder below the bottom cover; the upper shear ring is detachably embedded on the inner wall of the cylinder above the top cover; a confining pressure reaction frame, mounted in the loading space around the square test block; and, flexible loading mechanisms, disposed in pairs at two opposed side surfaces of the square test block.
    Type: Grant
    Filed: June 16, 2024
    Date of Patent: April 15, 2025
    Assignee: Institute of Rock and Soil Mechanics, Chinese Academy of Sciences
    Inventors: Qiang Xue, Xiaochun Li, Hang Ruan, Quan Jiang, Qingqian Wu
  • Patent number: 12279199
    Abstract: A method and an apparatus for supporting service continuity between a first network and a second network are provided, which include: requesting slice analytics for selection of a slice from a network data analytics function (NWDAF) of the first network before a terminal moves from the first network to the second network; and selecting a slice to be used in the second network to provide a service to the terminal based on the slice analytics received from the NWDAF of the first network.
    Type: Grant
    Filed: April 6, 2022
    Date of Patent: April 15, 2025
    Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Myung Ki Shin, Jihoon Sung, Soohwan Lee
  • Patent number: 12277272
    Abstract: An EMG-based control system is disclosed. The system includes an EMG sensor that streams data to a device. A neural network executed by the device decodes muscle activity into a two-dimensional continuous control signal. A network-based calibration routine optimizes the neural network to decode natural movements of the user.
    Type: Grant
    Filed: October 16, 2020
    Date of Patent: April 15, 2025
    Assignee: Rehabilitation Institute of Chicago
    Inventor: Ronald James Cotton
  • Patent number: 12277045
    Abstract: Disclosed is a method for timed pattern-based collaboration failure analysis in a platooning system-of-systems (SoS). A method for timed pattern-based collaboration failure analysis in a SoS performed by a computer device may include extracting an interaction collaboration failure pattern through a collaboration failure analysis in an interaction model generated from an interaction log executed in the SoS; and localizing a fault of an interaction bug from the extracted interaction collaboration failure pattern.
    Type: Grant
    Filed: May 18, 2023
    Date of Patent: April 15, 2025
    Assignee: Korea Advanced Institute Of Science And Technology
    Inventors: Doo-Hwan Bae, Sangwon Hyun, Jiyoung Song, Eun Kyoung Jee
  • Patent number: 12274809
    Abstract: Provided is a method of mineralizing tissue, including placing within a body of a subject a substance, wherein the substance includes osteopontin and osteocalcin. Also provided is a tissue mineralization-promoting substance including osteopontin and osteocalcin, and an article for promoting tissue mineralization, including an implant which may be an orthopedic implant or an endosseous implant, and a substance disposed on a surface of the implant including osteopontin, and osteocalcin. A method of making a tissue mineralization-promoting substance, including combining osteopontin and osteocalcin, is also provided. Other features, including calcium phosphate, type-I collagen, mesenchymal stem cells, and growth factors, are also provided.
    Type: Grant
    Filed: May 2, 2016
    Date of Patent: April 15, 2025
    Assignee: RENSSELAER POLYTECHNIC INSTITUTE
    Inventors: Atharva Abhay Poundarik, Marta Monteiro Silva Carvalho, Deepak Vashishth
  • Patent number: 12276724
    Abstract: The present disclosure discloses a method for suppressing the azimuth ambiguity of multi-channel SAR systems based on channel cancellation, which falls within the field of radar signal processing. The method includes: imaging echoed of the multi-channel SAR system based on a linear mapping reconstruction algorithm to obtain a reconstructed high-resolution wide-swath image; estimating positions of the azimuth ambiguity regions of the reconstructed high-resolution wide-swath image; extracting ambiguity images in the azimuth ambiguity regions based on channel cancellation and the refocusing algorithm; and suppressing a repetitive ambiguity image in imaging the echo of the multi-channel SAR system.
    Type: Grant
    Filed: November 26, 2024
    Date of Patent: April 15, 2025
    Assignee: Aerospace Information Research Institute, Chinese Academy of Sciences
    Inventors: Yu Wang, JunFeng Li, YongHua Cai, Bo Li, PingPing Lu
  • Patent number: 12277224
    Abstract: A system, method, and computer-program product includes commencing a parent computer process based on receiving a request to perform an analytical operation on one or more datasets, commencing at least one child computer process that is launched by the parent computer process when the parent computer process initiates an execution of the analytical operation on the one or more datasets, transmitting, by the at least one child computer process, a request to the parent computer process to retrieve the one or more datasets, writing, by the parent computer process, the one or more datasets to a cross-process queue based on the parent computer process receiving the requests, reading, by the at least one child computer process, the one or more datasets from the cross-process queue, and executing, using an analytical application executing on the least one child computer process, the analytical operation based on the one or more datasets.
    Type: Grant
    Filed: December 23, 2024
    Date of Patent: April 15, 2025
    Assignee: SAS INSTITUTE INC.
    Inventors: Mohammadreza Nazari, Xindian Long, Steven Eric Krueger, Joshua David Griffin, Lawrence Edmund Lewis, Amirhassan Fallah Dizche, Ralph Walter Abbey, Jorge Manuel Gomes Da Silva
  • Publication number: 20250119558
    Abstract: An image encoding method according to the present disclosure may include performing a low gradational conversion for an original depth image of a first bit depth to generate a first depth image of a second bit depth; and encoding the first depth image through a color image of a third bit depth. In this case, the third bit depth may be smaller than the second bit depth.
    Type: Application
    Filed: October 7, 2024
    Publication date: April 10, 2025
    Applicant: Electronics and Telecommunications Research Institute
    Inventors: Kwan-Jung OH, Gwangsoon LEE
  • Publication number: 20250116579
    Abstract: The present application disclose a device for preparing rock samples with different moisture contents, which comprises a sample container, wherein two ends of the rock sample are respectively connected with a first steam inlet and a first steam outlet of the sample container; the first steam outlet, a pump and a gas-liquid separator are connected in sequence, a gas outlet end of the gas-liquid separator, a steam compressor and the first steam inlet are connected in sequence, and a liquid outlet end of the gas-liquid separator, a steam generator and the steam compressor are connected in sequence. The water vapor in the sample container is pumped into the gas-liquid separator by the pump to separate low-temperature water vapor and condensate, and the low-temperature water vapor and condensate form high-temperature and high-pressure steam again and return to the inside of the sample container. The water in the steam generator always circulates inside the preparation device.
    Type: Application
    Filed: May 22, 2024
    Publication date: April 10, 2025
    Applicant: Institute of Geology and Geophysics, Chinese Academy of Sciences
    Inventors: Hang BIAN, Zhaobin ZHANG, Shouding LI, Xiao LI, Jianming HE, Bo ZHENG, Tianqiao MAO, Guanfang LI, Peng GUO