Abstract: Nitrogen-containing lipids prepared from the conjugate addition of amines to acrylates, acrylamides, or other carbon-carbon double bonds conjugated to electron-withdrawing groups are described. Methods of preparing these lipids from commercially available starting materials are also provided. These amine-containing lipids or salts forms of these lipids are preferably biodegradable and biocompatible and may be used in a variety of drug delivery systems. Given the amino moiety of these lipids, they are particularly suited for the delivery of polynucleotides. Complexes or nanoparticles containing the inventive lipid and polynucleotide have been prepared. The inventive lipids may also be used to in preparing microparticle for drug delivery. They are particularly useful in delivering labile agents given their ability to buffer the pH of their surroundings.

Abstract: A sensor system includes one or more gyroscopes and one or more accelerometers, for measuring subtle motions of a user's body. The system estimates physiological parameters of a user, such as heart rate, breathing rate and heart rate variability. When making the estimates, different weights are assigned to data from different sensors. For at least one estimate, weight assigned to data from at least one gyroscope is different than weight assigned to data from at least one accelerometer. Also, for at least one estimate, a weight assigned to one or more sensors located in a first region relative to the user's body is different than a weight assigned to one or more sensors located in a second region relative to the user's body. Furthermore, weight assigned to data from at least one sensor changes over time.

Abstract: The present invention provides a soil heavy metal curing agent for controlling accumulation of heavy metals of crops and its preparation method. The curing agent is made from the following parts of raw materials by weight: 60˜140 parts of substance containing carbon-carbon double bond; 1˜400 parts of sulfo-compound by sulfur; 50˜500 parts of organic matter by 10% water content; 0˜400 parts of water; 0˜100 parts of an initiator; 0˜200 parts of a reducer; and 0˜200 parts of a strong base. The curing agent for heavy metals in the soil according to the present invention can reduce the cadmium, lead and mercury content in the soil and further greatly reduce the roots absorption of these heavy metals.

Abstract: The present invention relates to the compounds of formula (I) or pharmaceutically acceptable salts thereof: wherein R1, R2, X, Y, A and B are defined in the description. Also disclosed in the present invention are the methods for preparing the compounds of formula (I) or pharmaceutically acceptable salts thereof, and pharmaceutical compositions comprising the compounds of formula (I) or pharmaceutically acceptable salts thereof.

Abstract: A refrigeration system and a heat exchanger are provided. The refrigeration system includes a compressor, a micro-channel condenser, a micro-channel evaporator and at least one throttling device which are connected by pipelines. Each of the micro-channel condenser and the micro-channel evaporator includes an inlet manifold and an outlet manifold, and a plurality of flat tubes being connected between the inlet manifold and the outlet manifold. The inlet manifold of the micro-channel evaporator is provided with a baffle, and the inlet manifold of the micro-channel evaporator is divided by the baffle into multiple manifold sections, and the manifold sections of the inlet manifold are isolated from each other by the baffle, and are each in communication with a certain number of the flat tubes, and are each not provided with a distribution pipe configured to distribute flow rate into the flat tubes in communication with the manifold sections.

Abstract: 8-[2-(2-pentyl-cyclopropylmethyl)-cyclopropyl]-octanoic acid has a protein tyrosine phosphatase 1B (PTP1B) inhibitory action, an Akt activating action, a GSK-3? phosphorylation promoting action, and a suppressive action on ? protein phosphorylation induced by A?1-42, and is useful as a therapeutic drug for Alzheimer-type dementia, an antidepressant and/or an anti-aging drug.

Abstract: A substrate structure and a device employing the same are disclosed. An embodiment of the disclosure provides the substrate structure including a flexible substrate and a first barrier layer. The flexible substrate has a top surface, a side surface, and a bottom surface. The first barrier layer is disposed on and contacting the top surface of the flexible substrate, wherein the first barrier layer consists of Si, N, and Z atoms, wherein the Z atom is selected from a group of H, C, and 0 atoms, and wherein Si of the first barrier layer is present in an amount from 35 to 42 atom %, N of the first barrier layer is present in an amount from 10 to 52 atom %, and Z of the first barrier layer is present in an amount from 6 to 48 atom %.

Abstract: The disclosure provides a pharmaceutical composition for inhibiting angiogenesis, including an effective amount of a lignan as an effective ingredient. The pharmaceutical composition may further include a pharmaceutically acceptable carrier or salt. The disclosure also provides a method for inhibiting angiogenesis, including administering an effective amount of a lignan as an effective ingredient for inhibiting angiogenesis to a subject in need thereof.

Abstract: An electrode structure of a fuel cell for power generation comprises an anodic structure, a cathodic structure, and an ionic exchange membrane disposed between the anodic and cathodic structures. The anodic and cathodic structures respectively are formed by multi-layer structures, to reduce the fuel crossover from the anodic structure to the cathodic structure, to reduce the catalysts applied amount, and to increase an output electrical energy of the fuel cell. The multi-layer structure of the anodic structure comprises a thin platinum alloy black layer, a Pt alloy layer disposed on the carbon material, and a substrate.

Abstract: A fuel-air premixer for use in a combustor of a gas turbine includes an air inlet, a fuel inlet, a shroud, a central body and a cascade of vanes. The premixer mixes fuel and air in the annular mixing passage into a uniform mixture for injecting into a combustor reaction zone. The air from a compressor is injected into the mixer through an air inlet. The fuel is introduced into air stream via fuel injection holes that pass through the walls of the vanes which contain internal fuel flow passages. The flow field inside the premixer is broken up by the arrayed vanes into a series of small regions each containing a well designed small size mixing eddy which is steadily attached to the surface of the vanes.

Abstract: Provided are a mash-up service generation apparatus and method based on a voice command. The mash-up service generation apparatus includes a voice recognizer configured to convert a voice command into a character string, a mash-up natural language processor configured to extract a word corresponding to a mash-up module based on the character string, and convert the word into at least one of metadata of the mash-up module and metadata of a mash-up sequence in which a plurality of mash-up modules are combined, and a mash-up sequence processor configured to search for and select a target mash-up sequence corresponding to the metadata of the mash-up sequence, and newly generate the target mash-up sequence. Accordingly, a customized mash-up service can be provided to a user.

Abstract: The present invention includes compositions and methods for increasing the effectiveness of antigen presentation using a DCIR-specific antibody or fragment thereof to which an antigen is attached that forms an antibody-antigen complex, wherein the antigen is processed and presented by a dendritic cell that has been contacted with the antibody-antigen complex.

Abstract: Provided are a dual-mode display device and a method of manufacturing the same. The device includes a lower substrate, an upper substrate facing the lower substrate, a thin-film transistor portion between the upper substrate and the lower substrate, a first anode on one side of the thin-film transistor portion, a first cathode between the first anode and the upper substrate, an organic light-emitting layer between the first cathode and the first anode, a second anode on the other side of the thin-film transistor portion, a second cathode between the second anode and the upper substrate, or the second anode and the lower substrate, and a optical switching layer between the second cathode and the second anode.

Abstract: A semiconductor memory device and a method for accessing the same are disclosed. The semiconductor memory device comprises a memory transistor, a first control transistor and a second control transistor, wherein a source electrode and a gate electrode of the first control transistor are coupled to a first bit line and a first word line respectively, a drain electrode and a gate electrode of the second control transistor are coupled to a second word line and a second bit line respectively, a gate electrode of the memory transistor is coupled to a drain electrode of the first control transistor, a drain electrode of the memory transistor is coupled to a source electrode of the second control transistor, and a source electrode of the memory transistor is coupled to ground, and wherein the memory transistor exhibits a gate electrode-controlled memory characteristic. The semiconductor memory device increases integration level and decreases refresh frequency.

Abstract: Small molecule compounds and methods for stem cell differentiation are provided herein. An example of a class of compounds that may be used to practice the methods disclosed herein is represented by enantiomerically pure isomers of compounds of Formula I: or a chirally pure stereoisomer, pharmaceutically acceptable salt, or solvate thereof, wherein R1, R2, R3, R4, R5, R5?, R6, R6?, R7, R7? are as described herein.

Abstract: The present invention relates to an intelligent lighting control apparatus and method, which control an intelligent lighting unit including multiple sensors depending on time, place, scene, environment, or the like, based on the results of sensing by the sensors. The intelligent lighting control apparatus includes a multi-sensor unit including multiple sensors, the multi-sensor unit sensing motion of a person or an object within a set sensing area using at least one of the multiple sensors. A lighting control unit controls an operation of a lighting unit based on frequency data corresponding to results of sensing by the multi-sensor unit and a class of lighting type corresponding to the frequency data.

Abstract: Methods and compositions for treating pain are disclosed. The compositions are based on dry powders comprising microparticles of diketopiperazines and an analgesic active agent. The analgesic in the compositions comprises one or more peptide analgesics or derivatives thereof, which are administered to a subject using a pulmonary inhalation drug delivery system comprising a dry powder inhaler and the analgesic composition. The present compositions produce fewer side effects associated with current opioid therapy.

Abstract: Systems and methods are disclosed that provide a direct indication of the presence and concentration of an analyte within the external cavity of a laser device that employ the compliance voltage across the laser device. The systems can provide stabilization of the laser wavelength. The systems and methods can obviate the need for an external optical detector, an external gas cell, or other sensing region and reduce the complexity and size of the sensing configuration.

Abstract: By driving molecules electrophoretically through a nanopore, single molecule detection can be achieved. To enhance translocational control, functionalized and non-functionalized electrodes are strategically placed around or above a nanopore. Changes in transmission spectra and input voltage detected by electrodes allow accurate identification of single molecules as they pass through a nanopore.

Abstract: This invention is related to a wireless communication system for giga bit data rate and low power consumption, comprising a mobile communication terminal that transmits massive data to a display apparatus using a millimeter wave or terahertz wave band, a display apparatus that plays received massive data and a low speed wireless controller that controls the operation of the mobile communication terminal and the transmission of massive data from the mobile communication terminal into the display apparatus.