Patents Assigned to INSTITUTE
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Patent number: 9210136Abstract: A major management apparatus, an authorized management apparatus, an electronic apparatus for delegation management, and delegation management methods thereof are provided. The major management apparatus generates a first and a second delegation deployment messages and respectively transmits them to the authorized management apparatus and the electronic apparatus. The authorized management apparatus encrypts an original authorized operation message into an authorized operation message by an authorization key included in the first delegation deployment message and transmits the authorized operation message to the electronic apparatus. The original authorized operation message includes an operation task message and a right level. The electronic apparatus decrypts the authorized operation message into the original authorized operation message by the authorization key included in the second delegation deployment message and performs an operation according to the operation task message and the right level.Type: GrantFiled: January 26, 2015Date of Patent: December 8, 2015Assignee: Institute For Information IndustryInventors: Jui-Ming Wu, You-Lian Huang, Chih-Chiang Hsieh, Emery Jou
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Patent number: 9205144Abstract: Methods for identifying at least one conserved peptide block in three or more homologous polypeptides are provided and compositions comprising conserved peptides are provided. More particularly, methods for selecting conserved peptides in variable viral polypeptides for use in immunogenic compositions are provided.Type: GrantFiled: June 4, 2012Date of Patent: December 8, 2015Assignee: Dana-Farber Cancer Institute, Inc.Inventors: Vladimir Brusic, Lars Ronn Olsen, Ellis L. Reinherz, Guanglan Zhang, Christian Simon
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Patent number: 9207290Abstract: A magnetic field sensor for sensing an external magnetic field is disclosed. The magnetic field sensor includes at least two magnetic tunneling junction (MTJ) elements disposed on an underlying electrode. Each of the MTJ elements is formed by a synthetic antiferromagnetic layer, a barrier layer and a free layer sequentially stacked together. A top electrode is then connected to the free layers. The free layer can be a single free layer, a composite free layer, a synthetic antiferromagnetic free layer or an alloy free layer. When a current is applied to a metal circuit passing over or below the MTJ elements, free magnetic moments generated by the MTJ elements are anti-parallel to each other along a reference axis, and the angles between the magnetic moments created by the MTJ elements and the reference axis are 40 to 50 degrees and 130 to 140 degrees, respectively.Type: GrantFiled: December 28, 2012Date of Patent: December 8, 2015Assignee: Industrial Technology Research InstituteInventors: Keng-Ming Kuo, Ding-Yeong Wang, Yung-Hung Wang
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Patent number: 9205423Abstract: High throughput screening of crystallization of a target material is accomplished by simultaneously introducing a solution of the target material into a plurality of chambers of a microfabricated fluidic device. The microfabricated fluidic device is then manipulated to vary the solution condition in the chambers, thereby simultaneously providing a large number of crystallization environments. Control over changed solution conditions may result from a variety of techniques, including but not limited to metering volumes of crystallizing agent into the chamber by volume exclusion, by entrapment of volumes of crystallizing agent determined by the dimensions of the microfabricated structure, or by cross-channel injection of sample and crystallizing agent into an array of junctions defined by intersecting orthogonal flow channels.Type: GrantFiled: February 25, 2013Date of Patent: December 8, 2015Assignees: California Institute of Technology, The Regents of the University of CaliforniaInventors: Carl L. Hansen, Stephen R. Quake, James M. Berger
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Publication number: 20150349376Abstract: An oxide-based solid electrolyte according to the present invention may be LixLa3M2O12 and may have a cubic phase. The oxide-based solid electrolyte may further include first and second dopants. A method of preparing an oxide-based solid electrolyte according to the concept of the present invention may include mixing a lithium compound, a lanthanum compound, a metal compound, a first dopant precursor, and a second dopant precursor to prepare an intermediate, and crystallizing the intermediate to prepare LixLa3M2O12 crystals having a cubic phase.Type: ApplicationFiled: January 29, 2015Publication date: December 3, 2015Applicant: Electronics and Telecommunications Research InstituteInventors: Dong Ok SHIN, Young-Gi LEE, Kunyoung KANG, Kwang Man KIM
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Publication number: 20150344571Abstract: The present invention relates to a novel antibody specifically binding to human and mouse L1CAM, and more particularly, to an antibody binding to both human and mouse L1CAM with high affinity, which is prepared by modifying a sequence of an L1 cell adhesion molecule (L1CAM)-specific antibody comprising a heavy-chain variable region of SEQ ID NO. 1 and a light-chain variable region of SEQ ID NO. 5, a polynucleotide encoding the antibody, an expression vector comprising the polynucleotide, a transformant introduced with the vector, a pharmaceutical composition for preventing or treating cancer comprising the antibody, a method for treating cancer using the antibody, a composition for diagnosing cancer comprising the antibody, a kit for diagnosing cancer comprising the composition, a method for providing information for cancer diagnosis using the antibody, and an antibody-drug conjugate prepared by conjugating a drug to the antibody.Type: ApplicationFiled: May 18, 2015Publication date: December 3, 2015Applicants: KANGWON NATIONAL UNIVERSITY University-Industry Cooperation Foundation, Korea Research Institute of Bioscience and BiotechnologyInventors: Hyo Jeong HONG, In Soo Park, Seul Ki Cho, Mun Sik Jeong, Singh Rohit
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Publication number: 20150344604Abstract: A method of preparing a fluoroelastomer capable of being vulcanized by using peroxide, the method comprising: in the presence of an initiator and a chain transfer agent, conducting emulsion polymerization reaction on comonomers to obtain a fluoroelastomer. The preparation method utilizes alkyl iodide RIx as the chain transfer agent, and introduces the atom I into the molecular structure of the polymer during the reaction, the atom I acting as a crosslinking point during peroxide vulcanization. The fluoroelastomer obtained via the preparation method greatly improves the performance after being vulcanized; in addition, due to the low cost and extensive sources of alkyl iodide, the preparation method also simplifies the manufacturing process, reduces cost, and has wide application prospects.Type: ApplicationFiled: November 25, 2013Publication date: December 3, 2015Applicant: Zhenghao Chenguang Research Institute of Chemical Industry Company LimitedInventors: Bo Zeng, Jianxin Zhang, Bin Li, Jun Lan, Jiayong Gao, Jing Bai
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Publication number: 20150348654Abstract: An organically cooled nuclear reactor comprises fissionable fuel pellets and a neutron-moderator matrix in which the fissionable fuel pellets are distributed. The neutron-moderator matrix also defines coolant channels for flow of an organic coolant.Type: ApplicationFiled: February 5, 2015Publication date: December 3, 2015Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGYInventors: Koroush Shirvan, Eric Christopher Forrest
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Publication number: 20150349369Abstract: Nonaqueous redox flow batteries (RFBs) can utilize a metal and a cation of the metal (Mn+) as an active redox couple for a first electrode and electrolyte, respectively, in a first half-cell. The RFBs can also utilize a second electrolyte having I-based species. The I-based species can be selected from the group consisting of I? anions, I2, anions of Ix (x?3), or combinations thereof. Two different ones of the I-based species compose a second redox active couple in the second half cell.Type: ApplicationFiled: June 3, 2014Publication date: December 3, 2015Applicant: BATTELLE MEMORIAL INSTITUTEInventors: Bin Li, Xiaoliang Wei, Zimin Nie, Wei Wang, Jun Liu, Vincent L. Sprenkle
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Publication number: 20150343567Abstract: A method and system for formation of vertical microvias in an opaque ceramic thin-plate by femtosecond laser pulses are introduced. The method includes (a) thin an opaque ceramic substrate and reduce its thickness to a range of 20-100 ?m to provide the ceramic thin-plate; (b) place the ceramic thin-plate on a carrier; and (c) drill the ceramic thin-plate by the femtosecond laser pulses, wherein the femtosecond laser pulses have the following parameters, including a pulse width <100 fs, a pulse frequency of 1,000˜10,000 Hz, a laser with a central wavelength of 800 nm, and a movable stage with a speed of 20-200 ?m/s. Hence, vertical mirovias with high aspect ratio can be fabricated in an opaque ceramic thin-plate.Type: ApplicationFiled: May 29, 2014Publication date: December 3, 2015Applicant: NATIONAL CHUNG SHAN INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Chih WANG, Chi-Haw CHIANG, Chih-Wei LUO, Sheng-Yang TSENG, Ya-Hsin TSENG, Hui-Hsin CHU
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Publication number: 20150348894Abstract: An electronic component and a method for fabricating the electronic component are provided. The electronic component includes a carrier, a first metal layer, a dielectric layer, a semiconductor layer, a flexible layer, at least one first opening, and at least one second metal layer. The first metal layer is disposed on the carrier. The dielectric layer is disposed on the first metal layer, and has a pattern consistent with a pattern of the dielectric layer. The semiconductor layer is disposed on the dielectric layer. The flexible layer is disposed on the carrier and encapsulates the first metal layer, the dielectric layer and the semiconductor layer. The flexible layer has a Young's modulus less than 40 GPa. The first opening penetrates the flexible layer. The second metal layer is disposed on the flexible layer and in the first opening and is electrically connected with the semiconductor layer.Type: ApplicationFiled: December 4, 2014Publication date: December 3, 2015Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Jing-Yi Yan, Wu-Wei Tsai, Wei-Cheng Kao, Wei-Han Chen
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Publication number: 20150343023Abstract: The invention provides methods and compositions for reducing, preventing or reversing cardio toxicity side effects associated with certain therapeutic agents. The invention also provides methods and compositions for treating heart dysfunction including heart failure, and for reversing the effects of myocardial infarction. The various aspects of the invention involve the use of ligand dimers, such as neuregulin dimers, that selectively induce the dimerization of certain EGF receptors in cardiac tissue.Type: ApplicationFiled: May 11, 2015Publication date: December 3, 2015Applicants: The Brigham and Women's Hospital, Inc., Massachusetts Institute of TechnologyInventors: Steven M. Jay, Linda G. Griffith, Richard T. Lee
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Publication number: 20150344897Abstract: The present invention is a method of shoot apical meristem transformation for monocot plant via sufficient and micro wounding (SMW). The technical process includes: expose the apical meristem by removing the coleoptile away when the shoot grows to 0.2-2 cm after 1-2 days of seed germination; make sufficient and micro wounding transformation to the apical meristem by stabbing and brushing for 2-3 times using the SMW brush having 100-5000 bristles which is 4-20 ?m in diameter for each one and 0.5-3 mm in exposed length, and dipped with the Agrobacterium tumefaciens containing binary vector harboring exogenous genes; develop the treated meristems directly to normal plants after co-cultivation; promote the plants to develop big spikes and set more seeds; harvest the seeds of T0 plants separately; detect and identify the transformation results in T1 generation which is bred from each individual T0 plant.Type: ApplicationFiled: September 14, 2012Publication date: December 3, 2015Applicant: HEBEI ACADEMY OF AGRICULTURE AND FORESTRY SCIENCES, INSTITUTE OF GENETICS AND PHYSIOLOGYInventors: Haibo Wang, Fushuang Dong, Mengyu Lv, Yanmin Zhang, Zhiheng Ren, Fan Yang, Xinchao Liang, Wenbo Zuo, Xueping Shi, Huanhuan Zhang, Yiping Gao, He Zhao, Xian Xu, Guozhong Sun, Jianfang Chai, Yongwei Liu, Jinyong Zhu, Qiufen Han, Qiang Zhang, Huijie Ma, Zhanwu Wang, Junfeng Guan
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Publication number: 20150347149Abstract: An apparatus includes a communications component to receive computer-executable query instructions to solve a MILP problem, the query instructions including a first expression conveying an objective function and side constraint that define a master problem of the MILP problem, a second expression conveying a mapping of graph data to a graph, and a third expression conveying a selection of a graph-based algorithm to solve a subproblem of the MILP problem; a subproblem component to replace the third expression with a fourth expression during decomposition of the MILP problem, the fourth expression including instructions to implement the graph-based algorithm to solve the subproblem; and an execution control component to perform iterations of solving the MILP problem that include executing the first expression to derive a solution to the master problem; and executing the fourth expression to derive a solution to the subproblem based on the mapping and the master problem solution.Type: ApplicationFiled: May 27, 2015Publication date: December 3, 2015Applicant: SAS INSTITUTE INC.Inventors: MATTHEW VICTOR GALATI, ROBERT WILLIAM PRATT, LEONARDO BEZERRA LOPES
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Publication number: 20150349208Abstract: Provided herein is a semiconductor light emitting device capable of increasing the light extraction efficiency and a fabricating method thereof, the device including a buffer layer formed on a substrate; an n-type semiconductor layer formed on the buffer; an active layer formed on a partial area of the n-type semiconductor layer such that the n-type semiconductor layer is exposed; a p-type semiconductor layer formed on the active layer; a transparent conductive layer formed on the p-type semiconductor layer; a first mesa surface formed along a side wall of the active layer from a side wall of the transparent conductive layer; a passivation layer formed along the first mesa surface; and a metal reflectance film formed along the passivation layer such that it re-reflects escaping light, thereby re-reflecting escaping light to increase the light extraction efficiency.Type: ApplicationFiled: January 14, 2015Publication date: December 3, 2015Applicant: Electronics and Telecommunications Research InstituteInventors: Dong Churl KIM, Sung Bock KIM, Jong Bae KIM, Ju Hee BAEK
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Publication number: 20150344408Abstract: New hydroxy aliphatic substituted phenyl aminoalkyl ether compounds of formula (I), compositions thereof and their use as a medicament in the treatment of nervous system diseases and/or the treatment of developmental, behavioral and/or mental disorders associated with cognitive deficits.Type: ApplicationFiled: December 20, 2013Publication date: December 3, 2015Applicant: PROUS INSTITUTE FOR BIOMEDICAL RESEARCH, S.A.Inventors: Josep R. PROUS, Neus SERRADELL, Ramon FLORES, Noemi GARCIA-DELGADO, Marcel-li CARBO BANUS
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Publication number: 20150349491Abstract: Provided herein is a distributed bragg reflector ridge laser diode that is capable of easily embodying a diffraction grating and that minimizes an optical absorption effect on a DBR area, and a fabricating method thereof, the distributed bragg reflector ridge laser diode including a lower clad layer formed on top of a substrate; an active core zone formed on top of the lower clad layer; a plurality of ridge wave guides formed on top of the active core zone such that they are spaced from one another and extend in an axial direction; and a diffraction grating formed on top of the active core zone and between the plurality of ridge wave guides.Type: ApplicationFiled: January 21, 2015Publication date: December 3, 2015Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTEInventors: Oh Kee KWON, Su Hwan OH, Chul Wook LEE
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Publication number: 20150346306Abstract: Provided is a pulse detection apparatus and a pulse detection method less susceptible to movement of a subject and less susceptible to noise. An oscillation frequency controller is configured to cause a frequency variable oscillator to oscillate at a predetermined oscillation frequency, which is a frequency within a range assumed as a resonance frequency of a molecule of a predetermined constituent constituting the blood flowing through a human body. The oscillation frequency controller also controls an oscillation frequency based on a phase difference signal and an amplitude signal, wherein the phase difference signal indicates the phase difference between a transmission signal transmitted from an antenna to the human body and a reception signal received by the antenna, and the amplitude signal indicates the magnitude of the amplitude of the received signal. A pulse detector detects the change of the amplitude signal in an amplitude direction as a pulse signal.Type: ApplicationFiled: November 19, 2013Publication date: December 3, 2015Applicant: KYUSHU INSTITUTE OF TECHNOLOGYInventor: Yasushi SATO
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Publication number: 20150344932Abstract: The invention provides methods and compositions for the rapid and sensitive detection of post-translationally modified proteins, and particularly of those with posttranslational glycosylations. The methods can be used to detect O-GlcNAc posttranslational modifications on proteins on which such modifications were undetectable using other techniques. In one embodiment, the method exploits the ability of an engine˜red mutant of ?-1,4-galactosyltransferase to selectively transfer an unnatural ketone functionality onto O-GlcNAc glycosylated proteins. Once transferred, the ketone moiety serves as a versatile handle for the attachment of biotin, thereby enabling detection of the modified protein. The approach permits the rapid visualization of proteins that are at the limits of detection using traditional methods. Further, the preferred embodiments can be used for detection of certain disease states, such as cancer, Alzheimer's disease, neurodegeneration, cardiovascular disease, and diabetes.Type: ApplicationFiled: December 23, 2014Publication date: December 3, 2015Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGYInventors: LINDA HSIEH-WILSON, NELLY KHIDEKEL, HWAN-CHING TAI, SABINE ARNDT
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Publication number: 20150348679Abstract: Problem There is proposed an innovative cross-sectional structure, with an idea contrary to the conventional one, utilizing the non-reactivity between Cu and Ta (or between Ag and Nb, Ta) in a high-temperature short-time heat treatment, thus achieving (1) the suppression of the low magnetic-field instability, (2) excellent wire drawability of a precursor wire, and (3) the reduction of the cost required for the incorporation of a stabilizer. Means for Resolution There is proposed a structure having an assembly of a plurality of single wires, wherein the assembly is covered with an outer cover (skin) formed from Nb or Ta, wherein each of the single wires has an Nb/Al composite filament region which is formed from a composite of Nb and Al mixed in an Nb:Al molar ratio of 3:1, and which is covered with a partition formed from Nb or Ta, and further covered with an interfilamentary barrier formed from Cu or Ag disposed around the partition.Type: ApplicationFiled: November 15, 2012Publication date: December 3, 2015Applicants: HITACHI CABLE, LTD., NATIONAL INSTITUTE FOR MATERIALS SCIENCE, INTER-UNIVERSITY RESEARCH INSTITUTE CORPORATIONInventors: Hitachi Cable, Ltd., Inter-University Research Institute Corporation, National Institute For Materials Science