Patents Assigned to INSTITUTE
  • Patent number: 9175330
    Abstract: A method of performing high-throughput screening of various enzymatic activities with high sensitivity using artificial genetic circuits is provided. Particularly, the invention is screening and quantifying the activity of isoprene biosynthesis enzymes using an artificial genetic circuit capable of sensing isoprene. The artificial genetic circuit comprises an isoprene-sensing transcriptional regulator which recognizes isoprene, at least one reporter gene, a isoprene-sensing transcriptional regulator binding region and promoters for genes encoding isoprene-sensing transcriptional regulators and reporter proteins. The artificial genetic circuit detects isoprene liberated from many enzymatic reactions and measures the activity of reporter genes. This system is widely applicable for high throughput and quantitative screening of isoprene biosynthesis enzymes and MEP/MVA pathway enzymes. Therefore, the invention can be advantageously used in the protein engineering technology for enzyme modification.
    Type: Grant
    Filed: February 20, 2013
    Date of Patent: November 3, 2015
    Assignee: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
    Inventors: Seung-Goo Lee, Seo Hyeon Kim, Jongsik Gam, Eugene Rha, Haseong Kim, Su-Lim Choi, EuiSung Choi
  • Patent number: 9175295
    Abstract: A modified transposon vector and a method for introducing a foreign gene into a cell are provided.
    Type: Grant
    Filed: July 4, 2006
    Date of Patent: November 3, 2015
    Assignee: THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTE
    Inventors: Kazuyoshi Kaminaka, Hiroaki Maeda, Masaki Hirashima, Ryoichi Kawamura, Junichi Matsuda, Takashi Kuwana
  • Patent number: 9173605
    Abstract: A fully integrated small size implantable sensing device is described, which can include a sensor and an electronic circuit to interface with the sensor and communicate with an external device. Various fabrication methods for the sensing device are described, including provision of wells, created using same fabrication technology as the electronic circuit, to contain electrodes of the sensor and corresponding functionalization chemicals. Such implantable sensing device can be used for a variety of electrochemical measuring applications within a living body as well as actuation by injecting a current into the living body.
    Type: Grant
    Filed: July 24, 2014
    Date of Patent: November 3, 2015
    Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Muhammad Mujeeb-U-Rahman, Meisam Honarvar Nazari, Mehmet Sencan, Axel Scherer
  • Patent number: 9176136
    Abstract: A hybridoma cell line ST03 having China Center for Type Culture Collection (CCTCC) accession number C2013187, a monoclonal antibody against aflatoxin biosynthetic precursor ST produced by the hybridoma cell line ST03, and the use of the monoclonal antibody. The hybridoma cell line ST03 can be used for preparing a high-titer monoclonal antibody against aflatoxin biosynthetic precursor ST, and the titer of mouse ascites antibody against aflatoxin biosynthetic precursor ST determined by enzyme linked immunosorbent assay (ELISA) can reach 6.4×105. The monoclonal antibody against aflatoxin biosynthetic precursor ST has high sensitivity, has 50% inhibiting concentration IC50 to aflatoxin biosynthetic precursor ST of 0.36 ng/mL, has no cross reaction with all of aflatoxin B1, aflatoxin B2, aflatoxin G1, and aflatoxin G2, and can be used for the content determination of aflatoxin biosynthetic precursor ST.
    Type: Grant
    Filed: March 24, 2015
    Date of Patent: November 3, 2015
    Assignee: OILCROPS RESEARCH INSTITUTE OF CHINESE ACADEMY OF AGRICULTURE SCIENCES
    Inventors: Peiwu Li, Min Li, Qi Zhang, Zhaowei Zhang, Xiaoxia Ding
  • Patent number: 9174926
    Abstract: The present invention relates to norbornene-ester-based derivatives, to a method for preparing same, and to the uses thereof. This compound may be used as a plasticizer which can replace a phthalate-based plasticizer.
    Type: Grant
    Filed: February 6, 2015
    Date of Patent: November 3, 2015
    Assignees: Sangmyung University Seoul Industry-Academic Cooperation Foundation, Korea Research Institute of Chemical Technology
    Inventors: Ju Hui Kang, Je Wan Woo, Yong Sung Park, Hyun Chul Oh, Jun Seong Park, Yi Wen Jin, Dae Hee Yun, Sang Jin Ko, Kun Wu Chung, Yeong Un Kim, Nam Kyun Kim
  • Patent number: 9179320
    Abstract: A method of assigning and managing reference signals in a multi-cell environment, and a network device and a terminal for applying the method, are provided. Reference signal patterns may be assigned to multiple femtocells through a long term coordination of a central control unit that is used to control multiple cells.
    Type: Grant
    Filed: October 19, 2010
    Date of Patent: November 3, 2015
    Assignees: Samsung Electronics Co., Ltd., Korea Advanced Institute Science and Technology
    Inventors: Won Jae Shin, Young Jun Hong, Chang Yong Shin, Yong Ho Cho, Dong Jo Park, Jung Hyun Park
  • Patent number: 9173564
    Abstract: Systems and methods of sensing intraocular pressure are described. An example miniaturized intraocular pressure (IOP) monitoring system is provided using a nanophotonics-based implantable IOP sensor with remote optical readout that can be adapted for both patient and research use. A handheld detector optically excites the pressure-sensitive nanophotonic structure of the IOP-sensing implant placed in the anterior chamber and detects the reflected light, whose optical signature changes as a function of IOP. Optical detection eliminates the need for large, complex LC structures and simplifies sensor design. The use of nanophotonic components improves the sensor's resolution and sensitivity, increases optical readout distance, and reduces its size by a factor of 10-30 over previous implants. Its small size and convenient optical readout allows frequent and accurate self-tracking of IOP by patients in home settings.
    Type: Grant
    Filed: December 17, 2012
    Date of Patent: November 3, 2015
    Assignees: California Institute of Technology, The Regents of the University of California
    Inventors: Hyuck Choo, David Sretavan, Myung-Ki Kim
  • Patent number: 9178284
    Abstract: The present disclosure relates to an electromagnetically transparent metamaterial, which comprises a substrate and a plurality of man-made metal microstructures arranged periodically inside the substrate. When an electromagnetic wave propagates through the metamaterial, each of the man-made metal microstructures is equivalent to two identical two-dimensional (2D) circuits, which are placed respectively in a direction perpendicular to an incident direction of the electromagnetic wave and in a direction parallel to the incident direction of the electromagnetic wave, and each of which comprises an inductor branch and two identical capacitor branches that are symmetrically connected in parallel with the inductor branch. The 2D circuits are associated with a waveband of the electromagnetic wave so that both a dielectric constant and a magnetic permeability of the metamaterial are substantially 1 when the electromagnetic wave propagates through the metamaterial.
    Type: Grant
    Filed: November 16, 2011
    Date of Patent: November 3, 2015
    Assignees: KUSNG-CHI INNOVATIVE TECHNOLOGY LTD., KUANG-CHI INSTITUTE OF ADVANCED TECHNOLOGY
    Inventors: Ruopeng Liu, Zhen Liao, Lin Luan, Zhiya Zhao
  • Patent number: 9174196
    Abstract: The present invention relates to a magnetite-birnessite mixture, to a synthesis method therefor, and to a water-treatment method using the same. The magnetite-birnessite mixture synthesis method according to the present invention includes: a first synthesis step in which magnetite is synthesized; a second synthesis step in which manganese is made to adsorb onto the surface of the magnetite by supplying manganese while maintaining a basic state in the presence of the magnetite, and then synthesizing birnessite on the surface of the magnetite by supplying an oxidizing agent and sodium, thereby synthesizing a mixture in which magnetite and birnessite are bound together; and a purification step in which the mixture of magnetite and birnessite is purified.
    Type: Grant
    Filed: July 7, 2011
    Date of Patent: November 3, 2015
    Assignee: KOREA INSTITUTE OF GEOSCIENCE AND MINERAL RESOURCES (KIGAM)
    Inventors: Jae-Gon Kim, Chul-Min Chun, Ho-Cheol Song, In-Hyun Nam, Dong-Wan Cho, Se-Eun Chang
  • Publication number: 20150311263
    Abstract: A pixel structure and an electroluminescent display having the same are disclosed. The pixel structure comprises a first pixel and a second pixel. The first pixel and the second pixel each comprise a first sub-pixel, a second sub-pixel and a third sub-pixel. The first sub-pixel of the first pixel is adjacent to the first sub-pixel of the second pixel, the second sub-pixel of the first pixel is adjacent to the second sub-pixel of the second pixel, and the third sub-pixel of the first pixel is adjacent to the third sub-pixel of the second pixel. The first sub-pixel of the first pixel is adjacent to the first sub-pixel of the second pixel in a first direction, and the second sub-pixel of the first pixel is adjacent to the second sub-pixel of the second pixel in a second direction that is not parallel to the first direction.
    Type: Application
    Filed: August 5, 2014
    Publication date: October 29, 2015
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Kai-Sheng SHIH, Yi-Shou TSAI, Kuan-Ting CHEN, Yu-Chun LIN, Wei-Ben WANG, Yu-Hsiang TSAI
  • Publication number: 20150311868
    Abstract: A Programmable-Gain Amplifier (PGA) has a digital value that programmably adjusts the gain of the analog amplifier. A variable capacitor has several switched sub-capacitors that are enabled by the digital value. Enabled sub-capacitors are switched between a sampled input and a virtual ground on one terminal, and connect to a summing node on the other terminal. The summing node connects to the inverting input of an op amp either through a switch or through a double-sampling capacitor that stores an offset. A feedback capacitor is in parallel with a sampling capacitor during a second clock phase when direct-charge transfer occurs, reducing power consumption of the amplifier. The feedback capacitor samples the sampled input during the first clock phase. The PGA gain is proportional to the sum of capacitances of enabled sub-capacitors. The gain can be adjusted for sensor inputs to an Analog Front-End (AFE), such as for an electro-cardiogram (ECG).
    Type: Application
    Filed: April 29, 2014
    Publication date: October 29, 2015
    Applicant: Hong Kong Applied Science & Technology Research Institute Company Limited
    Inventors: Ho Ming (Karen) WAN, Kwai Chi CHAN, Tin Ho (Andy) WU
  • Publication number: 20150311982
    Abstract: Devices and techniques for integrated optical data communication. An optical receiver may include a photodetector and a differential amplifier. The photodetector is coupled to an optical waveguide. The optical waveguide is configured to provide an optical signal encoding data. A first terminal of the differential amplifier is coupled to receive a photodetection signal from the photodetector. A second terminal of the differential amplifier is coupled to receive, from a noise measurement unit, a reference signal representing a noise component of the photodetection signal. The differential amplifier is configured to provide an amplifier signal encoding at least some of the data.
    Type: Application
    Filed: March 15, 2013
    Publication date: October 29, 2015
    Applicant: Massachusetts Institute of Technology
    Inventors: Michael Stephen Georgas, Jason Scott Orcutt, Vladimir Marko Stojanovic
  • Publication number: 20150311363
    Abstract: A transparent electrode can include a graphene sheet on a substrate, a layer including a conductive polymer disposed over the graphene sheet, and a plurality of semiconducting nanowires, such as ZnO nanowires, disposed over the layer including the conductive polymer.
    Type: Application
    Filed: November 26, 2013
    Publication date: October 29, 2015
    Applicant: Massachusetts Institute of Technology
    Inventors: Hyesung Park, Sehoon Chang, Jing Kong, Silvija Gradecak
  • Publication number: 20150311401
    Abstract: Contrary to conventional wisdom, which holds that light-emitting diodes (LEDs) should be cooled to increase efficiency, the LEDs disclosed herein are heated to increase efficiency. Heating an LED operating at low forward bias voltage (e.g., V<kBT/q) can be accomplished by injecting phonons generated by non-radiative recombination back into the LED's semiconductor lattice. This raises the temperature of the LED's active rejection, resulting in thermally assisted injection of holes and carriers into the LED's active region. This phonon recycling or thermo-electric pumping process can be promoted by heating the LED with an external source (e.g., exhaust gases or waste heat from other electrical components). It can also be achieved via internal heat generation, e.g., by thermally insulating the LED's diode structure to prevent (rather than promote) heat dissipation. In other words, trapping heat generated by the LED within the LED increases LED efficiency under certain bias conditions.
    Type: Application
    Filed: August 14, 2014
    Publication date: October 29, 2015
    Applicant: Massachusetts Institute of Technology
    Inventors: Parthiban Santhanam, Dodd Joseph Gray, Rajeev Jagga Ram
  • Publication number: 20150309788
    Abstract: Disclosed is a modularizing apparatus modularizing a function module in DDS middleware, including: a DCPS module providing an interface with an application program; and a library module initializing and creating the function module, classifying the created function module for each function and storing the classified function module, and providing a function module corresponding to a request by the DCPS module to the DCPS module.
    Type: Application
    Filed: November 19, 2014
    Publication date: October 29, 2015
    Applicant: Electronics and Telecommunications Research Institute
    Inventors: Hyung Kook JUN, Kyung Il KIM, Kyeong Tae KIM, Yong Yeon KIM, Je Man PARK, Soo Hyung LEE, Won Tae KIM
  • Publication number: 20150311319
    Abstract: One embodiment of present invention provides a method for manufacturing a semiconductor structure, which comprises: forming a gate stack on a semiconductor substrate and removing parts of the substrates situated on two sides of the gate stack; forming sidewall spacers on sidewalls of the gate stack and on sidewalls of the part of the substrate under the gate stack; forming doped regions in parts of the substrate on two sides of the gate stack, and forming a first dielectric layer to cover the entire semiconductor structure; selectively removing parts of the gate stack and parts of the first dielectric layer to form a channel region opening and source/drain region openings; forming a high K dielectric layer on sidewalls of the channel region opening; and implementing epitaxy process to form a continuous fin structure that spans across the channel region opening and the source/drain region openings.
    Type: Application
    Filed: August 17, 2012
    Publication date: October 29, 2015
    Applicant: Institute of Microelectronics, Chinese Academy of Sciences
    Inventors: Qingqing Liang, Huicai Zhong, Huilong Zhu, Chao Zhao, Tianchun Ye
  • Publication number: 20150308103
    Abstract: Provided in one embodiment is a method of modifying an air flow at least one location of a building structure, comprising: generating a first air flow at the at least one location of the building structure; and modifying a second air flow exterior to the building structure using the generated first air flow. An apparatus configured to modified an air flow is also provided.
    Type: Application
    Filed: March 15, 2013
    Publication date: October 29, 2015
    Applicant: Rensselaer Polytechnic Institute
    Inventors: Anna Dyson, Jason Vollen, Michael Amitay, Peter Stark, Ajith Rao, Edward DeMauro, David Menicovich
  • Publication number: 20150307786
    Abstract: A catalyst is described that is useful for catalytic pyrolysis of biomass to produce a pyrolysis product. The catalyst includes (i) matrix material comprising a support and/or binder, and (ii) at least one metal oxide on the matrix material, wherein the metal oxide comprises metal selected from the group consisting of tungsten, chromium, cobalt, molybdenum, nickel, and combinations thereof. Corresponding catalytic pyrolysis processes and catalytic pyrolysis apparatus are disclosed, in which the catalyst enables the production of low oxygen content, stable liquid intermediates that can be refined to make liquid hydrocarbon fuels.
    Type: Application
    Filed: December 4, 2013
    Publication date: October 29, 2015
    Applicant: RESEARCH TRIANGLE INSTITUTE
    Inventors: David C. Dayton, PhD, Maruthi Sreekanth Pavani, John R. Carpenter III, Matthew Von Holle
  • Publication number: 20150307385
    Abstract: In illustrative implementations of this invention, a crucible kiln heats glass such that the glass becomes or remains molten. A nozzle extrudes the molten glass while one or more actuators actuate movements of the nozzle, a build platform or both. A computer controls these movements such that the extruded molten glass is selectively deposited to form a 3D glass object. The selective deposition of molten glass occurs inside an annealing kiln. The annealing kiln anneals the glass after it is extruded. In some cases, the actuators actuate the crucible kiln and nozzle to move in horizontal x, y directions and actuate the build platform to move in a z-direction. In some cases, fluid flows through a cavity or tubes adjacent to the nozzle tip, in order to cool the nozzle tip and thereby reduce the amount of glass that sticks to the nozzle tip.
    Type: Application
    Filed: April 27, 2015
    Publication date: October 29, 2015
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: John Klein, Giorgia Franchin, Michael Stern, Markus Kayser, Chikara Inamura, Shreya Dave, Neri Oxman, Peter Houk
  • Publication number: 20150309567
    Abstract: A gaze tracking device includes a first image acquisition unit installed at a right side of a face of a user to acquire a side image of a right eye, a second image acquisition unit installed at a left side of the face of the user to acquire a side image of a left eye, a fixing unit to fix the first image acquisition unit and the second image acquisition unit, and a gaze tracking unit to track a gaze position of the user by deriving a pupil and iris area, a sclera area, and an angle between eyelids from the side image of the right eye and the side image of the left eye. Accordingly, accurate gaze tracking is ensured while realizing a compact and lightweight gaze tracking device.
    Type: Application
    Filed: July 8, 2014
    Publication date: October 29, 2015
    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Ji Hyung PARK, Joong Ho LEE, Chul Woo CHO