Abstract: Described herein are composites that are relatively lightweight, high strength and low thermal conductivity. Also described herein are methods for the manufacture and use thereof.

Abstract: The present disclosure is directed to lenses, devices, methods and/or systems for addressing refractive error. Certain embodiments are directed to changing or controlling the wavefront of the light entering a human eye. The lenses, devices, methods and/or systems can be used for correcting, addressing, mitigating or treating refractive errors and provide excellent vision at distances encompassing far to near without significant ghosting. The refractive error may for example arise from myopia, hyperopia, or presbyopia with or without astigmatism. Certain disclosed embodiments of lenses, devices and/or methods include embodiments that address foveal and/or peripheral vision. Exemplary of lenses in the fields of certain embodiments include contact lenses, corneal onlays, corneal inlays, and lenses for intraocular devices both anterior and posterior chamber, accommodating intraocular lenses, electro-active spectacle lenses and/or refractive surgery.

Abstract: Disclosed herein are a new N2,N4-bis(4-(piperazin-1-yl)phenyl)pyrimidin-2,4-diamine derivative or a pharmaceutically acceptable salt thereof and a pharmaceutical composition for the prevention or treatment of cancers containing the same as an active ingredient. The compound of the present invention has excellent inhibitory effects against the activities of anaplastic lymphoma kinase (ALK) and activated cdc42-associated kinase (ACK1) and thus can improve the therapeutic effects on the treatment of cancer cells having anaplastic lymphoma kinase fusion proteins such as EML4-ALK and NPM-ALK, and also effectively prevent the recurrence of cancers thus being useful as a pharmaceutical composition for the prevention and treatment of cancers.

Abstract: Disclosed herein are a Desktop As A Service (DaaS) manager and DaaS client for a DaaS system. The DaaS manager includes a connection broker module, a provisioning module, a management module, and a web server module. The connection broker module permits connections to a DaaS client and a DaaS server to a user who has performed user authentication. The provisioning module determines the operating status of the DaaS server, and assigns a virtual machine of an optimum DaaS server to the DaaS client. The management module monitors the operating status of the DaaS server and the virtual machine, and executes a control command of the DaaS server. The web server module provides a web-based management tool Graphic User Interface (GUI) to the user.

Abstract: The present application discloses a method for manufacturing a semiconductor structure, comprising the steps of: a) providing a p-type field effect transistor; b) forming a tensile-stressed layer on the p-type field effect transistor; c) removing a portion of the tensile-stressed layer, so that the remaining portion of the tensile-stressed layer generates compressive stress in the channel of the p-type field effect transistor; and d) performing annealing, so as to achieve the object of memorizing compressive stress in a channel of a transistor and improving the performance of the transistor. The method according to the present invention memorizes the compressive stress in the channel of the transistor by a stress memorization technique, increases mobility of holes, and improves overall performance of the semiconductor structure.

Abstract: The present invention relates to TNFR2-IL21R fusion protein acting as a double-antagonist to TNF-alpha (?) and IL-21. The composition containing the double antagonist to TNF-? and Il-21 (TNFR2-IL21R fusion protein), known as major causes of autoimmune rheumatoid arthritis, one of autoimmune diseases, can reduce the secretion of inflammatory cytokine, increase the secretion of anti-inflammatory cytokine, and suppress the differentiation of osteoclasts better than single proteins such as TNFR2-Fc and IL21R-Fc. The TNFR2-IL21R fusion protein of the present invention has not only excellent treatment effect on arthritis in CIA mouse model not also excellent treatment effect on autoimmune rheumatoid arthritis by increasing the expression of Treg, the immune suppressive cells. Therefore, the TNFR2-IL21R fusion protein of the present invention can be effectively used as an active ingredient for the composition for the prevention and treatment of autoimmune disease.

Abstract: Presented herein is a rechargeable lithium battery that includes a cathode, a liquid electrolyte, a solid electrolyte, and an anode. The anode is at least partially coated or plated with the solid electrolyte. The cathode may be porous and infiltrated by the liquid electrolyte. The cathode may also include a binder having a solid graft copolymer electrolyte (GCE). In certain embodiments, the liquid electrolyte is a gel that includes a PIL and a GCE. The battery achieves a high energy density and operates safely over a wide range of temperatures.

Abstract: A wide viewing angle holographic image display method and apparatus are disclosed. The wide viewing angle holographic image display apparatus includes a scan line unit and a control unit. The scan line unit includes a plurality of lateral scan lines that represent different angles, respectively. The control unit performs control so that different data are output at the respective different angles, represented by the lateral scan lines, using the plurality of lateral scan lines.

Abstract: The invention provides an isolated antigen polypeptide that can be expressed in a subject with ovarian cancer. Also provided is the diagnosis of ovarian cancer by using the antigen polypeptide of the invention and the prevention and/or treatment of ovarian cancer by suppressing the gene of the antigen polypeptide of the invention.

Abstract: The present invention provides an apparatus for producing micro liquid drops through fine channels which can produce a large amount of micro liquid drops at low costs in an efficient manner. The apparatus for producing micro liquid drops according to the present invention includes a fine channel substrate and a holder for holding the fine channel substrate.

Abstract: The invention describes HLA class II binding peptides encoded by the SSX-2 tumor associated gene, as well as nucleic acids encoding such peptides and antibodies relating thereto. The peptides stimulate the activity and proliferation of CD4+ T lymphocytes. Methods and products also are provided for diagnosing and treating conditions characterized by expression of the SSX-2 gene.

Abstract: A method for obtaining, with high selectivity as compared to a conventional method of mixing reaction substrates and thereafter reacting the mixture under heating, a facial isomer of tris-orthometallated iridium that is suitably used particularly as an organic electroluminescence device material, among complexes of tris-orthometallated iridium. The method for producing a complex of tris-orthometallated iridium according to the present disclosure includes, in order, a step (1) of preliminarily heating at least one of the complex of orthometallated iridium or the bidentate organic ligand; a step (2) of mixing the complex of orthometallated iridium and the bidentate organic ligand; and a step (3) of reacting the complex of orthometallated iridium and the bidentate organic ligand.

Abstract: Provided is a recycling method for producing calcite and ammonium sulfate having a high purity of at least 95% and generated by means of a carbonation reaction for fixing carbon dioxide inside the crystal structure of a mineral, and in which waste gypsum is reacted with carbon dioxide, which is a greenhouse gas, such that the carbon dioxide is fixed as a stable mineral, and high-purity calcite and ammonium sulfate are produced as resultant products.

Abstract: Methods for the formation of liposomes that encapsulate reagents in a continuous 2-phase flow microfluidic network with precision control of size, for example, from 100 nm to 300 nm, by manipulation of liquid flow rates are described. By creating a solvent-aqueous interfacial region in a microfluidic format that is homogenous and controllable on the length scale of a liposome, fine control of liposome size and polydispersity can be achieved.

Abstract: Systems and methods are provided for producing fluids with desired concentration factors. According to one embodiment, an arrangement of digital microfluidic (DMF) based electrode platforms are provided. The arrangement may be configured to carry out a sequence of mix steps that may demand storage of resultant fluid mixtures produced in intermediate mix steps. Such sequences of mix steps may be desirable as a result of the decreased demand for initial fluid samples, and reduced wastage.

Abstract: The invention presents a method for analyzing speech in a spoken dialog system, comprising the steps of: accepting an utterance by at least one means for accepting acoustical signals, in particular a microphone, analyzing the utterance and obtaining prosodic cues from the utterance using at least one processing engine, wherein the utterance is evaluated based on the prosodic cues to determine a prominence of parts of the utterance, and wherein the utterance is analyzed to detect at least one marker feature, e.g. a negative statement, indicative of the utterance containing at least one part to replace at least one part in a previous utterance, the part to be replaced in the previous utterance being determined based on the prominence determined for the parts of the previous utterance and the replacement parts being determined based on the prominence of the parts in the utterance, and wherein the previous utterance is evaluated with the replacement part(s).

Abstract: The present invention relates to a method for making 3D stereo digital broadcast service compatible in an MPEG-2-TS format which is used for transmitting and receiving digital TV. To this end, suggested is a method for transmitting detailed information which supports both TS-level multiplexing and ES-level multiplexing when left and right compressed bitstreams are multiplexed, when service compatibility is enabled.

Abstract: The present invention discloses a method for manufacturing a palladium-platinum core-shell catalyst for a fuel cell. More specifically, the present invention discloses a method for manufacturing a palladium-platinum core-shell catalyst for a fuel cell, in which a platinum shell nano particle epitaxially grown on a palladium core is synthesized and dipped in a carbon support, thereby manufacturing the palladium-platinum core-shell catalyst for a hydrogen fuel cell, such that mass production of a uniform size is possible. Additionally, the techniques herein reduce the requirement for the use of expensive metal, which reduces the manufacturing cost of a fuel cell. Moreover, is the techniques herein are applicable to the field of high-efficiency hydrogen fuel cells having superior electric catalytic activity and durability.

Abstract: The present invention provides methods of identifying candidate agents for treating excitotoxicity-related disorders. The present invention further provides methods for treating excitotoxicity-related disorders.

Abstract: The invention provides immunogenic polysaccharide protein conjugates comprising capsular polysaccharides from N. Meningitidis serogroup X and methods for preparation thereof. The present invention relates to N. meningitidis X saccharide-carrier protein conjugates prepared by a conjugation reaction. Accordingly, the instant invention relates to multivalent meningococcal polysaccharide protein conjugate composition comprising capsular saccharide from serogroups X and at least one capsular saccharide from A, C, W135 and Y wherein, i) polysaccharides A C W135 X are sized mechanically whereas polysaccharide Y is sized chemically, ii) all saccharide are conjugated to carrier protein via a linker with a cyanylation conjugation chemistry iii) all saccharide to protein ratios in final conjugates are between 0.2-0.6 and iv) at least two different carrier proteins selected from the group consisting of TT, DT and CRM197 are utilized.