Patents Assigned to INSTITUTE
  • Patent number: 9101593
    Abstract: Methods of treating a mammal at risk for ischemia-reperfusion injury are provided. The methods comprise administrating an adrenomedullin binding protein-1 (AMBP-1) to the mammal in sufficient amount to reduce the injury. Also provided are methods of treating a mammal at risk for ischemia-reperfusion injury to the bowel. The methods comprise administering adrenomedullin to the mammal in sufficient amount to reduce the injury.
    Type: Grant
    Filed: February 28, 2014
    Date of Patent: August 11, 2015
    Assignee: The Feinstein Institute for Medical Research
    Inventor: Ping Wang
  • Patent number: 9102727
    Abstract: The present invention is based, in part, on the identification of novel human anti-PD-1, PD-L1, and PD-L2 antibodies. Accordingly, the invention relates to compositions and methods for diagnosing, prognosing, and treating conditions that would benefit from modulating PD-1, PD-L1, and/or PD-L2 activity (e.g., persistent infectious diseases, autoimmune diseases, asthma, transplant rejection, inflammatory disorders and tumors) using the novel human anti-PD-1, PD-L1, and PD-L2 antibodies described herein.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: August 11, 2015
    Assignees: EMORY UNIVERSITY, DANA-FARBER CANCER INSTITUTE, INC.
    Inventors: Gordon J. Freeman, Rafi Ahmed, Timothy D. Jones, Francis J. Carr, James P. Gregson
  • Patent number: 9107122
    Abstract: A method and an apparatus for correcting wireless signal quality are provided. The apparatus includes an abnormality detector and a quality adjuster. The abnormality detector collects multiple measurement values reported by a user equipment (UE), calculates a variation degree value according to the measurement values, and compares the variation degree value with a predetermined threshold value. The measurement values are generated by the UE when the UE measures the wireless signal quality of an evolved node B. The measurement values include a first reference signal receiving quality (RSRQ) of the evolved node B. When the variation degree value is larger than the predetermined threshold value, the quality adjuster corrects the first RSRQ based on the measurement values to generate a second RSRQ of the evolved node B.
    Type: Grant
    Filed: February 4, 2013
    Date of Patent: August 11, 2015
    Assignee: Industrial Technology Research Institute
    Inventors: Chia-Lung Liu, Chun-Hao Tseng, Ming-Chia Lee
  • Patent number: 9102056
    Abstract: The present invention relates to a control method and device for position-based impedance controlled industrial robot, and more particularly, a control method and device for position-based impedance controlled industrial robot able to improve contact stabilization with regard to an environment with a variety of stiffness. According to a control method and device for position-based impedance controlled industrial robot in accordance with the present invention, a robust contact stabilization for a position-based impedance controlled industrial robot contacting and interacting with an uncertain actual environment may be guaranteed.
    Type: Grant
    Filed: December 30, 2013
    Date of Patent: August 11, 2015
    Assignee: GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Je Ha Ryu, Sehun Kim
  • Patent number: 9103022
    Abstract: The present disclosure relates to an amorphous aluminum alloy coating. The aluminum alloy coating may specifically include one of cerium, cobalt and/or molybdenum as alloying elements and be applied by a physical vapor deposition process to a desired thickness. The coating may supply improved corrosion resistance to a given environmental condition.
    Type: Grant
    Filed: October 1, 2007
    Date of Patent: August 11, 2015
    Assignee: SOUTHWEST RESEARCH INSTITUTE
    Inventors: Ronghua Wei, Marta Jakab, Craig Engel
  • Patent number: 9101326
    Abstract: A method of image reconstruction is provided. When an object is not placed in a measurement space, first intensity images of an electromagnetic wave passing through the measurement space and corresponding to photon energy levels are measured. When the object is placed in the measurement space, second intensity images of the electromagnetic wave passing through the object and corresponding to photon energy levels are measured. In a database, data including an attenuation coefficient of each substance respectively having components irradiated by the electromagnetic wave corresponding to each photon energy level and a thickness of each substance in a transmission direction of the electromagnetic wave corresponding to each photon energy level are provided. Attenuation images of the object respectively corresponding to the components are calculated according to the data and the first and second intensity images. An image reconstruction system and a method and system of image construction are also provided.
    Type: Grant
    Filed: June 11, 2013
    Date of Patent: August 11, 2015
    Assignee: Industrial Technology Research Institute
    Inventors: Meng-Han Tsai, Jheng-You Lin, Hsin-Han Shen, Guo-Zua Wu
  • Patent number: 9104942
    Abstract: This invention, which relates to retrieving an object from a video or a photo where the object matches a hand-drawn sketch, discloses a method for automatically estimating a perceptual bias level with respect to a feature of the sketch. The method allows estimation based on the sketch alone without involving an extra database. In one embodiment, the method comprises using an expectation-maximization tensor voting (EMTV) method to analyze a statistical distribution of the feature. The statistical distribution is analyzed by forming an objective function having the statistical distribution's information parameterized by the perceptual bias level, and then maximizing the objective function according to a set of iterative update rules. In another embodiment, the method for automatically estimating a perceptual bias level is incorporated into a method for retrieving one or more objects from an image or video database where the one or more objects match a hand-drawn sketch.
    Type: Grant
    Filed: December 19, 2012
    Date of Patent: August 11, 2015
    Assignee: Hong Kong Applied Science and Technology Research Institute Company Limited
    Inventors: Tai Pang Wu, Zhiqian Li, Kenneth Kwan Yee Wong
  • Patent number: 9103710
    Abstract: An apparatus and method for monitoring a flow of liquid in a pipe are provided. The apparatus may include a temperature sensor attached to a pipe of a heat exchanger system to measure a temperature of the pipe, and a controller to determine whether a liquid is present in the pipe, based on a change in the measured temperature.
    Type: Grant
    Filed: December 22, 2011
    Date of Patent: August 11, 2015
    Assignees: Korea Atomic Energy Research Institute, Korea Hydro & Nuclear Power Co. Ltd.
    Inventors: Tae Joon Kim, Ji Young Jeong, Yong Bum Lee, In Koo Hwang, Jae Hyuk Eoh, Jong Man Kim, Yeong Ii Kim
  • Patent number: 9102782
    Abstract: The present invention relates to a transparent copolyester, wherein the transparent copolyester comprises an aliphatic-aromatic copolyester segment A, a segment B having repeating units —O—CH(CH3)—C(O)—, and structural units C derived from polyisocyanate(s), wherein the weight ratio for the segment A, segment B and structural unit C is 100:(100-2000):(0.1-10) and wherein the weight-average molecular weight Mw of the transparent copolyester is from 50,000 to 1,000,000. The present invention further relates to a preparation method for a transparent copolyester, including polymerizing lactide, a hydroxyl-terminated aliphatic-aromatic copolyester and a polyisocyanate in the presence of a catalyst; wherein the weight ratio for the aliphatic-aromatic copolyester, lactide and polyisocyanate is 100:(100-2000):(0.1-10). The present invention further relates to a transparent copolyester prepared by said method and an article made from the transparent copolyester according to present invention.
    Type: Grant
    Filed: August 9, 2012
    Date of Patent: August 11, 2015
    Assignees: China Petroleum & Chemical Corporation, Beijing Research Institute of Chemical Industry, China Petroleum & Chemical Coporation
    Inventors: Ning Xu, Guixiang Zhu, Wei Zhang, Ling Han, Yi Zou, Wenxi Ji
  • Patent number: 9101695
    Abstract: Devices and methods for the treatment of open and closed wound spinal cord injuries are disclosed. For example, described herein are devices and methods for mitigating secondary injury to, and promoting recovery of, spinal cord primary injuries. More particularly, certain embodiments of the present invention are directed to polymeric mini-tubes that may be used for the treatment of spinal cord injuries. In addition, other embodiments are directed to polymeric “fill-in” bandages that may be used for the treatment of spinal cord injuries. For example, an erodible, or biodegradable, form of biocompatible polymer of the present invention is fabricated for surgical implantation into the site of the spinal cord injury.
    Type: Grant
    Filed: September 25, 2014
    Date of Patent: August 11, 2015
    Assignees: Children's Medical Center Corporation, Massachusetts Institute of Technology
    Inventors: Robert S. Langer, Rajiv Saigal, Yang Teng
  • Patent number: 9102474
    Abstract: A rotation mechanism includes a mandrel, a rotation axle, a needle roller bearing and an angular bearing. The mandrel includes a shaft portion, a first annular contact portion and a second annular contact portion. The shaft portion has an outer surface, and the first annular contact portion and the second annular contact portion are located on the outer surface and respectively surround the axis of the mandrel. The rotation axle includes an annular portion, a third annular contact portion and a fourth annular contact portion. The annular portion has a shaft hole and an inner surface forming the shaft hole. The third annular contact portion and the fourth annular contact portion are located on the inner surface, and the mandrel passes through the shaft hole. The needle roller bearing is in contact with the first annular contact portion and the third annular contact portion, and is located between them.
    Type: Grant
    Filed: February 10, 2014
    Date of Patent: August 11, 2015
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Wei-Chu Lin, Mei-Chin Chou, Yu-Shiang Huang, Hsin-Chuan Su, Hsi-Hung Hsiao
  • Patent number: 9101666
    Abstract: Poly(?-amino esters) prepared from the conjugate addition of bis(secondary amines) or primary amines to a bis(acrylate ester) are described. Methods of preparing these polymers from commercially available starting materials are also provided. These tertiary amine-containing polymers are preferably biodegradable and biocompatible and may be used in a variety of drug delivery systems. Given the poly(amine) nature of these polymers, they are particularly suited for the delivery of polynucleotides. Nanoparticles containing polymer/polynucleotide complexes have been prepared. The inventive polymers may also be used to encapsulate other agents to be delivered. They are particularly useful in delivering labile agents given their ability to buffer the pH of their surroundings.
    Type: Grant
    Filed: September 17, 2013
    Date of Patent: August 11, 2015
    Assignee: Massachusetts Institute of Technology
    Inventors: Robert S. Langer, David M. Lynn, David A. Putnam, Mansoor M. Amiji, Daniel Griffith Anderson
  • Patent number: 9102388
    Abstract: The present invention relates to an emergency position indicating radio beacon (EPIRB) terminal for confirming positions of ships and rescuing the ships during a marine disaster in a marine search and rescue system and an apparatus and a method for monitoring an operating state of the EPIRB terminal. The EPIRB terminal comprises: a sensor unit for sensing the sinking of a ship in which the EPIRB terminal is provided; a generation unit for generating a distress message corresponding to the sensed result of the sensor unit; and a transmission unit for broadcasting a distress signal including the distress message. The sensor unit comprises: a water-pressure sensor for outputting a water-pressure detection signal by sensing the water pressure in the inside of the ship; a moisture sensor for outputting a moisture detection signal by sensing the moisture inside the ship; and a separation sensor for outputting a separation detection signal by sensing the separation of the EPIRB terminal from the ship.
    Type: Grant
    Filed: March 11, 2011
    Date of Patent: August 11, 2015
    Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Jeom-Hun Lee, Sanguk Lee
  • Patent number: 9103834
    Abstract: The present invention relates generally to methods for identifying drug side effects by detecting perturbations in organ-specific molecular blood fingerprints. The invention further relates to methods for identifying drug-specific organ-specific molecular blood fingerprints. As such, the present invention provides compositions comprising organ-specific proteins, detection reagents for detecting such proteins, and panels and arrays for determining organ-specific molecular blood fingerprints.
    Type: Grant
    Filed: December 9, 2013
    Date of Patent: August 11, 2015
    Assignee: Institute for Systems Biology
    Inventors: Leroy Hood, Biaoyang Lin
  • Patent number: 9105816
    Abstract: A light emitting apparatus has a first radiation source without a dome, a substantially transparent and light transmissive optic device devoid of scattering particles and phosphor, a lens, a down conversion material containing phosphor that is disposed on the planar top surface of the optic device between the lens and the radiation source, and a heat sink, upon which the radiation source is mounted, having a recess formed therein in which the radiation source, the optic device and the down conversion material are positioned, wherein an air space is defined between a boundary of the recess and the optic device.
    Type: Grant
    Filed: February 4, 2014
    Date of Patent: August 11, 2015
    Assignee: Rensselaer Polytechnic Institute
    Inventors: Nadarajah Narendran, Yimin Gu
  • Patent number: 9105363
    Abstract: A method for collecting volatile radioactive substances. The method includes irradiating a volatile radioactive substance on or under a contaminated material surface using microwave radiation and vaporizing the volatile radioactive substance, wherein the volatile radioactive substance comprises at least one of cesium and iodine. The method further includes recovering the vaporized volatile radioactive substance from the contaminated material. The method may be accomplished with and/or without physically collecting or isolating the contaminated material.
    Type: Grant
    Filed: December 3, 2012
    Date of Patent: August 11, 2015
    Assignee: SOUTHWEST RESEARCH INSTITUTE
    Inventors: Roland R. V. Benke, Ralph H. Hill, Jr., Roberto T. Pabalan, James A. Moryl, Jeremy R. Pruitt
  • Patent number: 9107185
    Abstract: The present invention relates to a method for efficient transmission of a request frame such as an RTS/CTS frame and a response frame in response to the request frame in a multi-user based wireless communication system. The method of the present invention comprises: a process where wireless terminals transmit a response frame at their own response frame transmission time through a request frame that contains information about a plurality of wireless terminals and information about the response frame transmission time of the respective wireless terminals; a process where the respective wireless terminals transmit a response frame according to a token scheme such that the response frame is transmitted to a final access point; and a process where only a representative wireless terminal selected depending on a given wireless environment receives the response frame.
    Type: Grant
    Filed: May 23, 2012
    Date of Patent: August 11, 2015
    Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Yun-Joo Kim, Jeeyon Choi, Sok-Kyu Lee
  • Patent number: 9105548
    Abstract: A method and device for imaging or detecting electromagnetic radiation is provided. A device structure includes a first chip interconnected with a second chip. The first chip includes a detector array, wherein the detector array comprises a plurality of light sensors and one or more transistors. The second chip includes a Read Out Integrated Circuit (ROIC) that reads out, via the transistors, a signal produced by the light sensors. A number of interconnects between the ROIC and the detector array can be less than one per light sensor or pixel.
    Type: Grant
    Filed: June 22, 2012
    Date of Patent: August 11, 2015
    Assignee: California Institute of Technology
    Inventors: Thomas J. Cunningham, Bruce R. Hancock, Chao Sun, Todd J. Jones, Matthew R. Dickie, Shouleh Nikzad, Michael E. Hoenk, Christopher J. Wrigley, Kenneth W. Newton, Bedabrata Pain
  • Patent number: 9103046
    Abstract: The present invention is directed to composite films containing nanostructures within a polymer or monomeric matrix which composite may be formed on a metallic substrate and subsequently removed to provide bulk material. The nanostructures and polymer or monomer matrix may be assembled electrophoretically by initially providing a mixture of the nanostructures and polymer or monomer matrix material within generally anhydrous environments such as polar aprotic solvents followed by deposition of the composite film material.
    Type: Grant
    Filed: July 7, 2010
    Date of Patent: August 11, 2015
    Assignee: SOUTHWEST RESEARCH INSTITUTE
    Inventors: Benjamin R. Furman, Stephen T. Wellinghoff, Charles K. Baker
  • Patent number: 9102583
    Abstract: A process for producing ethylene glycol includes contacting an oxalate with a fluidized bed catalyst under the following conditions: a reaction temperature of from about 170 to about 270° C., a weight space velocity of oxalate of from about 0.2 to about 7 hours?1, a hydrogen/ester molar ratio of about 20˜200:1, a reaction pressure of from about 1.5 to about 10 MPa, and a reaction temperature difference T of from about 1 to about 15° C. The fluidized bed catalyst includes: a) from about 5 to about 80 parts by weight of copper and the oxide thereof, b) from about 10 to about 90 parts by weight of at least one carrier selected from silica, molecular sieve or alumina, c) from about 0.01 to about 30 parts by weight of bismuth and tungsten metallic elements or the oxides thereof, or cerium and niobium metallic elements or the oxides thereof.
    Type: Grant
    Filed: February 24, 2012
    Date of Patent: August 11, 2015
    Assignees: CHINA PETROLEUM & CHEMICAL CORPORATION, SHANGHAI RESEARCH INSTITUTE OF PETROCHEMICAL TECHNOLOGY, SINOPEC
    Inventors: Weimin Yang, Juntao Liu, Wanmin Wang, Jun Kuai