Patents Assigned to INSTITUTE
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Publication number: 20150218610Abstract: This invention relates to a method for producing a protein of interest, comprising introducing a protein expression vector which comprises a gene fragment a gene fragment comprising a DNA encoding a protein of interest and a selectable marker gene and transposon sequences at both terminals of the gene fragment, into a suspension mammalian cell; integrating the gene fragment inserted between a pair of the transposon sequences, into a chromosome of the mammalian cell to obtain a mammalian cell capable of expressing the protein of interest; and suspension-culturing the mammalian cell; and a suspension mammalian cell capable of expressing the protein of interest.Type: ApplicationFiled: April 17, 2015Publication date: August 6, 2015Applicants: KYOWA HAKKO KIRIN CO., LTD, Inter-University Research-Institute Corporation Research Organization of Information & SystemsInventors: Koichi KAWAKAMI, Keina YAMAGUCHI, Risa OGAWA, Masayoshi TSUKAHARA
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Publication number: 20150221848Abstract: Provided are a thermoelectric device and a method of manufacturing the same. The thermoelectric device includes a substrate, a first electrode having a first comb shape connected to one side of the substrate and open to the other side of the substrate, a second electrode having a second comb shape connected to the other side of the substrate and open to the one side of the substrate and inserted into the first electrode, and first and second thermoelectric medium layers disposed between the first electrode and the second electrode and alternately disposed in a direction apart from the substrate.Type: ApplicationFiled: July 29, 2014Publication date: August 6, 2015Applicant: Electronics and Telecommunications Research InstituteInventors: Taehyoung ZYUNG, Moon Gyu JANG
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Publication number: 20150218204Abstract: The invention involves the synthesis of nucleic acid structures of controlled size and shape and comprised of a plurality of oligonucleotides. The structures are formed, at least in part, by the self-assembly of single-stranded oligonucleotides. The location of each oligonucleotide in the resultant structure is known. Accordingly, the structures may be modified with specificity.Type: ApplicationFiled: July 24, 2013Publication date: August 6, 2015Applicants: President and Fellows of Harvard College, Dana-Farber Cancer Institute, Inc.Inventors: Peng Yin, William M. Shih, Yonggang Ke, Luvena L. Ong
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Publication number: 20150218642Abstract: The invention provides a primer group for detecting CpO island methylation of p16 gene using methylation specific fluorescence technique. The primer group comprises a pair of oligonucleotide primers and a fluorescence-labeled probe. Said oligonucleotide primer pair has base sequence represented by SEQ ID NO.1 and SEQ ID NO.2. Said fluorescence-labeled probe has base sequence represented by SEQ ID NO.3 or SEQ NO.4.Type: ApplicationFiled: January 1, 2011Publication date: August 6, 2015Applicant: Beijing Institute For Cancer ResearchInventors: Dajun Deng, Jing Zhou
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Publication number: 20150223298Abstract: The present disclosure provides an AC-direct-type LED-lighting device including compensation circuit for AC input compensation, including a compensation inductor and first compensation capacitor parallelly connected to one terminal of AC input and a second compensation capacitor connected in series; rectifying unit for rectifying output from second compensation capacitor terminals to obtain direct current; and LED array driven by the rectifying unit output, wherein capacities of the first and second compensation capacitors and the compensation inductor and LED array output voltage are determined to cause 0.9 or larger cosine value of a phase, with respect to the AC input voltage, of resulting current obtained by dividing AC input voltage by sum of (i) parallel value of an equivalent impedance Re of the rectifying unit and LED array and an impedance of the second compensation capacitor and (ii) parallel value of impedances of the compensation inductor and first compensation capacitor.Type: ApplicationFiled: August 29, 2013Publication date: August 6, 2015Applicants: Optomind Inc., Korea Advanced Institute of Science and TechnologyInventors: Chun-taek Rim, Eun-Soo Lee, Bo-hwan Choi, Bong-cheol Kim
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Publication number: 20150218018Abstract: An aspect of the invention relates a wastewater treatment module using a membrane distillation. The wastewater treatment module includes: an inflow-water side including a space for receiving feed water; a treated-water side including a space for receiving treated water, wherein the treated-water side coupled to the inflow-water side; and a separation membrane interposed between the inflow-water side and the treated-water side. The separation membrane has a bent shape.Type: ApplicationFiled: February 12, 2014Publication date: August 6, 2015Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Seockheon Lee, Seong Pil Jeong
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Publication number: 20150218201Abstract: The invention provides compounds of formula I, wherein R1, R2 and R3 have values defined in the specification and a pharmaceutically acceptable salt thereof; or an optical isomer thereof; or a mixture of optical isomers, as well as compositions comprising such compounds and therapeutic methods that utilize such compounds and/or compositions.Type: ApplicationFiled: April 19, 2010Publication date: August 6, 2015Applicant: Institute of Organic Chemistry and Biochemistry ASCR, V.V.I.Inventors: Aurelie Bourderioux, Michal Hocek, Petr Naus
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Publication number: 20150221998Abstract: The present invention provides an energy storage system, particularly a battery system, that is capable of preventing self from overheating, comprising at least one energy storage unit each having two terminal posts extending outwards from the interior thereof; when there are at least two energy storage units, electrical connection therebetween is achieved by electrical connection elements that bridge the terminal posts of different energy storage units; at least one of the terminal posts and/or the electrical connection elements is in thermal connection with a heat transfer surface enlarging structure made of solid heat conductive materials. The present invention further relates to a method for preventing overheat of an energy storage system.Type: ApplicationFiled: April 20, 2012Publication date: August 6, 2015Applicant: National Institute of Clean-And-Low-Carbon EnergyInventors: Hong Jin, George H. Brilmyer, Michael T. Nispel, Dongxue Ren, Dajun BAI
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Publication number: 20150221303Abstract: Provided are a discussion learning system enabling a discussion learning to proceed based on a speech recognition system without an instructor and a method using the same, the discussion learning system including an learning content providing server configured to provide a discussion environment, extract speeches of learners joining a discussion, and generate speech information based on the extracted speeches, and a speech recognition server configured to perform a speech recognition with respect to each of the learners based on the speech information, determine a progress of the discussion based on a result of the speech recognition, and provide the learning content providing server with interpretation information for smoothly continuing the discussion.Type: ApplicationFiled: January 13, 2015Publication date: August 6, 2015Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTEInventors: Jeom Ja KANG, Hyung Bae JEON, Yun Keun LEE, Ho Young JUNG
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Publication number: 20150217279Abstract: A catalyst for generating hydrogen containing at least one composite metal selected from the group consisting of a composite metal of platinum and nickel and a composite metal of iridium and nickel, the catalyst being used in a decomposition reaction of at least one compound selected from the group consisting of hydrazine and a hydrate thereof; and a method for generating hydrogen, including contacting the catalyst for generating hydrogen with at least one compound selected from the group consisting of hydrazine and a hydrate thereof. Hydrogen can be efficiently generated with improved selectivity in the method for generating hydrogen that utilizes the decomposition reaction of hydrazine.Type: ApplicationFiled: April 14, 2015Publication date: August 6, 2015Applicant: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGYInventors: Qiang Xu, Sanjay Kumar Singh
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Publication number: 20150218524Abstract: There is described a process for production of metal-coated virus particles or metallic nanoparticles, said process comprising admixing virus particles with plant material with reducing power and a metal salt, wherein the process can be provided in planta or ex planta and the virus particles aid the production of the metal-coated virus particles or metallic nanoparticles.Type: ApplicationFiled: September 20, 2013Publication date: August 6, 2015Applicant: THE JAMES HUTTON INSTITUTEInventors: Andrew John Love, Mikhail Emmanuilovich Talianski, Sean Nicholas Chapman, Jane Shaw
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Publication number: 20150218193Abstract: Water-soluble derivatives and/or prodrugs of acacetin are described herein. The compounds can be used as cardioprotection agents against myocardial infarction induced by ischemia-reperfusion. In one embodiment the compounds are used to treat ischemic cardiac diseases. In the preferred embodiment, the compounds are used to treat and/or prevent myocardial infarction in humans.Type: ApplicationFiled: February 3, 2014Publication date: August 6, 2015Applicants: Shanghai Institute of Pharmaceutical Industry, Versitech LimitedInventors: Gui-Rong Li, Feng Lin
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Publication number: 20150218182Abstract: In addition to containing and protecting the viral genome, the capsid (protein shell) of hepatitis B virus (HBV) plays critical roles in the viral life cycle including regulation of intracellular trafficking and nucleic acid metabolism. Substituted pyrimidine modulators of the assembly of the HBV capsid structure and methods for their use are described.Type: ApplicationFiled: August 2, 2012Publication date: August 6, 2015Applicants: INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION, SCRIPPS RESEARCH INSTITUTE, A NOT-FOR-PROFIT PUBLIC BENEFIT CORPORATION OF CALIFORNIAInventors: Adam Zlotnick, M.G. Finn
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Publication number: 20150219574Abstract: There is provided a calorimeter. Heat flows in and out of the sample via a thermoelectric module. The thermoelectric module is so constituted that a pair of a P-type thermoelectric element and an N-type thermoelectric element is disposed between substrates, and the pair of the thermoelectric elements are connected in n pairs so that the P-type thermoelectric elements and the N-type thermoelectric element are arranged alternately in ?-shape; a calorimetric sensitivity of the thermoelectric module of a thermal conductance surrounding thermoelectric module and a thermal conductance between substrates of the thermoelectric modules and a noise based on an electric resistance of the thermoelectric module depend on an L/A ratio of the thermoelectric element constituting the thermoelectric module and the number n of the pairs of the thermoelectric elements, where the L/A ratio is 6 mm?1 or more, and the number n of the pairs is 4 or more.Type: ApplicationFiled: August 7, 2013Publication date: August 6, 2015Applicant: NATIONAL UNIVERSITY CORPORATION KYOTO INSTITUTE OF TECHNOLOGYInventor: Haruhiko Yao
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Publication number: 20150222485Abstract: A computer-program product causing a processor component to identify requisite configuration information for executing an application routine by the processor component, wherein the requisite configuration information enables the application routine to communicate with another computing device via a network during execution of the application routine; generate an API that specifies the requisite configuration information to a resource device via the network when the resource device accesses the API via the network; operate a network interface that couples the processor component to the network to make the API accessible to the resource device via the network to enable the resource device to provide the requisite configuration information; and relay the requisite configuration information following provision of the requisite configuration information by the resource device to the application routine for use during execution of the application routine and to a start component to trigger a start of execution ofType: ApplicationFiled: February 6, 2015Publication date: August 6, 2015Applicant: SAS Institute Inc.Inventor: Darren Key
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Publication number: 20150221981Abstract: A solid polymeric electrolyte and a lithium battery with the same. The electrolyte includes a polymer matrix, which may have a mesh structure with the polymer matrix being formed of a cured photo-crosslinking agent. The electrolyte also includes inorganic particles distributed in the polymer matrix, and a lithium salt and an organic solvent impregnated between the polymer matrix and the inorganic particles. The electrolyte has a first portion, a second portion, and a third portion connecting the first and second portions, wherein one of the first, second, and third portions is located apart from a flat plane connecting the others. The lithium battery includes an anode electrode provided with an anode active material and an anode current collector, and a cathode electrode provided with a cathode active material and a cathode current collector and disposed to face the anode electrode, with the electrolyte interposed between the two electrodes.Type: ApplicationFiled: April 17, 2015Publication date: August 6, 2015Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTEInventors: Young-Gi LEE, Kwang Man KIM, Dong Ok SHIN, Kunyoung KANG, Sang-Young LEE, Eun-Hye KIL, Keunho CHOI
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Publication number: 20150216195Abstract: An improved apparatus for processing sea cucumbers having stages for orienting/aligning, cutting, splitting, flattening, eviscerating and cleaning the sea cucumber, and for collecting the eviscerated innards. A method for the automated splitting and evisceration of sea cucumbers using the apparatus of the present disclosure. A flattening plate and trough during the orienting/aligning step relax the sea cucumber and discourage its defence mechanisms. A wedge shaped flattening plate splits and flattens the sea cucumber immediately after the incision. Pronged discs maintain positioning of the sea cucumber during an aggressive wash and brush cleaning cycle, which may be repeated. Optionally, a vacuum may suction off a portion of the innards prior to cleaning.Type: ApplicationFiled: August 15, 2013Publication date: August 6, 2015Applicants: Marine Institute of Memorial University of Newfoundland, Canadian Centre for fisheries Innovation, Genesis Group Inc., Memorial University of NewfoundlandInventors: Joseph Singleton, Mark Ingerman, Stephen King
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Publication number: 20150219595Abstract: A process for analyzing a sample by a capillary electrophoresis method is provided that allows for high analytic precision and reduction in apparatus size, and can be readily carried out by electrophoresing a complex of a sample and an anionic group-containing compound in the capillary channel, wherein the capillary channel includes an A layer that is coated on an inner wall thereof and a B layer that is coated on the A layer, where the A and B layers are as described.Type: ApplicationFiled: April 14, 2015Publication date: August 6, 2015Applicants: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY, ARKRAY, Inc.Inventors: Yoshihide Tanaka, Shinichi Wakida, Yusuke Nakayama, Satoshi Yonehara
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Publication number: 20150216416Abstract: A method and system for medical imaging employs an excitation source configured to cause an object having a plurality of cells to at least one of emit, reflect, and fluoresce light. An optical receptor is employed that is configured to receive the light from the object. A filter assembly receives the light from the optical receptor and filters the light. An image processor having a field of view (FOV) substantially greater than a diameter of a cell of the object and an analysis resolution substantially matched to the diameter of a cell of the object that receives the filtered light from the filter and analyzes the filtered light corresponding to each cell in the FOV. A feedback system is provided that is configured to provide an indication of a state of each cell in the FOV and a location of a cell in the FOV meeting a predetermined condition.Type: ApplicationFiled: February 6, 2015Publication date: August 6, 2015Applicants: Massachusetts Institute of Technology, Duke UniversityInventors: Moungi G. Bawendi, Jorge M. Ferrer, W. David Lee, Lisa F. Marshall, David G. Kirsch
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Publication number: 20150217379Abstract: The present invention relates to an apparatus and method for attenuation of vibration in a machine tool, and more particularly, to an apparatus and method for attenuation of vibration in a machine tool in which a vibration of a machine tool is measured, and generates an identical frequency with a piezoelectric actuator as well as changes a phase for making dissipative interference of a generated vibration wave form.Type: ApplicationFiled: September 11, 2013Publication date: August 6, 2015Applicant: KOREA INSTITUTE OF MACHINERY & MATERIALSInventors: Dong-Hoon Kim, Joon Yub Song