Patents Assigned to INSTITUTE
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Publication number: 20140295080Abstract: This invention relates to a board and method for forming a graphene layer, and more particularly, to a board for use in forming a graphene layer, which has a structure able to improve properties of the graphene layer formed thereon, and to a method of forming a high-quality graphene layer using the same. The board of the invention includes a board layer, a metal catalyst layer formed on the board layer and functioning as a catalyst for forming the graphene layer, and a stress reduction layer disposed between the board layer and the metal catalyst layer so as to reduce stress of the metal catalyst layer, wherein the stress reduction layer able to reduce stress of the metal thin film is provided, thus improving crystallinity and surface roughness of the metal thin film, thereby effectively forming a high-quality graphene layer.Type: ApplicationFiled: December 18, 2013Publication date: October 2, 2014Applicant: Korea Advanced Institute of Science and TechnologyInventors: Byung Jin Cho, Jeong Hun Mun
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Publication number: 20140294924Abstract: The present invention includes compositions and methods for regenerating glucose-responsive cells by ultrasound-targeted microbubble destruction in the pancreas, wherein the composition comprises a pre-assembled liposome-nucleic acid complex in contact with within and about a microbubble, wherein the pre-assembled liposome-nucleic acid complex comprises a NeuroD gene under the control of the promoter, wherein disruption of the microbubble in the pancreas at a target site delivers the nucleic acid into pancreas cells at the location of the ultrasound disruption, wherein cells that incorporate the nucleic acid express insulin in response to high blood glucose levels.Type: ApplicationFiled: February 26, 2014Publication date: October 2, 2014Applicant: Baylor Research InstituteInventors: Paul A. Grayburn, Shuyuan Chen, Jiahuan Ding
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Publication number: 20140296479Abstract: The present invention is characterized by a D-Aptamer-Like Peptide (D-Aptide) or retro-inverso Aptide which specifically binds to a target comprising: (a) a structure stabilizing region comprising parallel, antiparallel or parallel and antiparallel D-amino acid strands with interstrand noncovalent bonds; and (b) a target binding region I and a target binding region II comprising randomly selected n and m D-amino acids, respectively, and coupled to both ends of the structure stabilizing region. The D-Aptide or retro-inverso Aptide has the sequence of the same or opposite direction to L-Aptide, wherein the stability to proteases is improved while maintaining the affinity to a target compared with L-Aptide. The D-Aptide of the present invention has substantially the same target affinity and a remarkably improved stability compared with L-Aptide which is different from a general technical knowledge.Type: ApplicationFiled: April 6, 2012Publication date: October 2, 2014Applicant: GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Sang-Yong Jon, Sung-Hyun Kim
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Publication number: 20140296160Abstract: Novel polypeptides and methods of making and using the same are described herein. The polypeptides include cross-linking (“hydrocarbon stapling”) moieties to provide a tether between two amino acid moieties, which constrains the secondary structure of the polypeptide. The polypeptides described herein can be used to treat diseases characterized by excessive or inadequate cellular death.Type: ApplicationFiled: November 1, 2013Publication date: October 2, 2014Applicants: President and Fellows of Harvard College, Dana-Farber Cancer Institute, Inc.Inventors: Loren D. Walensky, Stanley J. Korsmeyer, Gregory Verdine
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Patent number: 8846488Abstract: The invention relates to a semiconductor device and a method for manufacturing such a semiconductor device. A semiconductor device according to an embodiment of the invention may comprise: a substrate; a device region located on the substrate; and at least one stress introduction region separated from the device region by an isolation structure, with stress introduced into at least a portion of the at least one stress introduction region, wherein the stress introduced into the at least a portion of the at least one stress introduction region is produced by utilizing laser to illuminate an amorphized portion comprised in the at least one stress introduction region to recrystallize the amorphized portion. The semiconductor device according to an embodiment of the invention produces stress in a simpler manner and thereby improves the performance of the device.Type: GrantFiled: November 30, 2011Date of Patent: September 30, 2014Assignee: Institute of Microelectronics, Chinese Academy of SciencesInventors: Qingqing Liang, Huaxiang Yin, Huicai Zhong, Huilong Zhu
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Patent number: 8849265Abstract: A mobile personal-computing device may categorize a selected contact by collecting from the user information related to the selected contact's behavior and/or personality style. After obtaining communication hints for effectively communicating with similarly categorized individuals. The mobile personal-computing device modifies a remote or local contacts database such that when the user communicates with the selected contact, the mobile personal-computing device will automatically provide the communication hints to the user.Type: GrantFiled: December 14, 2012Date of Patent: September 30, 2014Assignee: Effectiveness Institute, Inc.Inventor: Clifford Chirls
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Patent number: 8848199Abstract: The present invention relates to systems and methods for quantitative three-dimensional mapping of refractive index in living or non-living cells, tissues, or organisms using a phase-shifting laser interferometric microscope with variable illumination angle. A preferred embodiment provides tomographic imaging of cells and multicellular organisms, and time-dependent changes in cell structure and the quantitative characterization of specimen-induced aberrations in high-resolution microscopy with multiple applications in tissue light scattering.Type: GrantFiled: July 10, 2008Date of Patent: September 30, 2014Assignee: Massachusetts Institute of TechnologyInventors: Wonshik Choi, Ramachandra Rao Dasari, Christopher M. Fang-Yen, Michael S. Feld
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Patent number: 8846630Abstract: The present invention provides a pharmaceutical composition for treating cancer, comprising at least one selected from deoxyribonucleic acids (DNA) for encoding small interfering RNA (siRNA) which complementarily binds to the base sequence of the transcript (mRNA transcript) of the FLJ25416 gene, represented by sequence number 3, sequence number 5, and sequence number 7 to inhibit the intracellular expression of the FLJ25416 gene, antisense RNA which inhibits expression of the FLJ25416 gene, and short hairpin RNA (shRNA) which inhibits expression of the FLJ25416 gene. As the siRNA, which is complementary to the base sequence of the transcript (mRNA transcript) of the FLJ25416 gene, the antisense RNA, and the shRNA, according to the present invention, inhibit expression of the FLJ25416 gene which is known to be expressed in cancer cells, and thus kill cancer cells, the composition of the present invention can be used as a novel anti-cancer agent.Type: GrantFiled: November 1, 2010Date of Patent: September 30, 2014Assignee: Korea Research Institute of Bioscience and BiotechnologyInventors: Misun Won, Kyung-Sook Chung, Young Joo Kim, Hye Kyung Hong, Young Il Yeom, Chae Ok Yun, Yu-Kyoung Oh, Kyung Bin Song, Hee Gu Lee, Young Ho Kim, Moon Hee Kim, Kyeong-Eun Jung, Seok Hoon Song
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Patent number: 8848700Abstract: Disclosed is device-to-device communication based on a cellular communication network. A method of operating a terminal capable of supporting D2D (device to device) communication based on a cellular communication network may include: determining whether to perform central control D2D communication or distributed control D2D communication; and performing the distributed control D2D communication, or requesting a setting for the central control D2D communication to a base station on the basis of the determination. With the D2D communication based on the cellular communication network, the cellular communication, the central control D2D communication, or the distributed control D2D communication may flexibly and selectively operate in the cellular network.Type: GrantFiled: September 28, 2012Date of Patent: September 30, 2014Assignee: Electronics and Telecommunications Research InstituteInventors: Jae Young Ahn, Choong Il Yeh, Kyoung Seok Lee
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Patent number: 8847702Abstract: Systems and methods which utilizes a stub array microstrip line for providing a phase shifter configuration are shown. A stub array microstrip line phase shifter of embodiments may comprises a microstrip line structure, an isolation structure, and a phase tuning structure cooperative to provide phase shifting of signals passed through the microstrip line structure. A microstrip line structure comprises a stub array microstrip line having a plurality of microstrip stubs provided in association with a slotted ground plane having a plurality of slots. The stub array microstrip line is adapted to provide compensation for capacitance and/or inductance associated with the slots of the slotted ground plane. A phase tuning structure provides coupling of signals transmitted by the stub array microstrip line to the slots of the slotted ground plane for signal phase shifting.Type: GrantFiled: September 26, 2011Date of Patent: September 30, 2014Assignee: Hong Kong Applied Science and Technology Research Institute Co., Ltd.Inventors: Hau Wah Lai, Angus C. K. Mak, Corbett R. Rowell
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Patent number: 8846358Abstract: In a step of contacting an organic material including formic acid ions and a carbon source other than the formic acid ions with a microorganism having a formate dehydrogenase gene and a hydrogenase gene under an anaerobic condition, concentration of the formic acid ions in the organic material is set to be not less than 0.01 mol/L and not more than 0.5 mol/L, and concentration of the carbon source is set to not less than 0.1 mmol/L and not more than 200 mmol/L. This allows continuously producing hydrogen for a long time, without dropping the ability of the microorganism to produce hydrogen.Type: GrantFiled: May 5, 2009Date of Patent: September 30, 2014Assignees: Sharp Kabushiki Kaisha, Research Institute of Innovative Technology for the EarthInventors: Akihito Yoshida, Hideaki Yukawa, Masayuki Inui
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Patent number: 8847836Abstract: An antenna structure comprises a substrate, a first antenna unit and a second antenna unit. The substrate comprises a first surface and a second surface opposing the first surface. The first antenna unit is disposed on the first surface, and comprises at least a first slot with a wider inside and narrower outside at the edge of the first antenna unit. The second antenna unit is disposed on the second surface, and is connected to the first antenna unit through a hole in the substrate. The radius of the at least one first slot is one-fourth the wavelength of the central frequency of the antenna structure.Type: GrantFiled: May 11, 2011Date of Patent: September 30, 2014Assignee: Industrial Technology Research InstituteInventors: Ya Chung Yu, Chin Chung Nien, Jenn Hwan Tarng, Jun Yen Huang, Chen Ming Li, Li Yuan Chang
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Patent number: 8846785Abstract: The invention provides a method for manufacturing spherical, monodispersed core-shell type ceria-polymer hybrid nanoparticles including, a mixing step in which a cerium salt and a polymer are mixed together in a high-boiling-point organic solvent to obtain a mixture, and a heating and reflux step in which this mixture is heated and refluxed at a temperature of 110° C. or more to thereby generate a boiling phenomenon in the heating and reflux step, and rapidly cooling the mixture after the heating and reflux step to precipitate cerium oxide, and a liquid dispersion thereof.Type: GrantFiled: December 23, 2009Date of Patent: September 30, 2014Assignee: National Institute of Advanced Industrial Science and TechnologyInventors: Noriya Izu, Ichiro Matsubara, Toshio Itoh, Woosuck Shin, Maiko Nishibori, Toshio Uchida
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Patent number: 8845526Abstract: A multi-purpose device that can be used, as, among other things, an otoscope and a three dimensional scanning system is disclosed.Type: GrantFiled: June 27, 2012Date of Patent: September 30, 2014Assignee: Massachusetts Institute of TechnologyInventors: Douglas P. Hart, Federico Frigerio, Douglas M. Johnston, Manas C. Menon, Daniel Vlasic
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Patent number: 8847637Abstract: Described are a multi-modulus frequency divider and event counter that are based on time-interleaved signals generated from a received signal. For the frequency divider, each time-interleaved clock signal generated from a received clock signal is provided to a bit counter and the output signal from each bit counter is provided to a multiplexer. A multiplexer selection module controls over time which one of the output signals from the bit counters is presented at the output of the multiplexer. The transition frequency of the bits in the time-interleaved clock signals allows various circuit components such as the bit counters to be implemented as CMOS components. Thus the frequency divider is more power-efficient than conventional frequency divider circuits operating at high clock frequencies.Type: GrantFiled: May 24, 2012Date of Patent: September 30, 2014Assignee: Massachusetts Institute of TechnologyInventor: Matthew C. Guyton
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Patent number: 8846143Abstract: Methods for fastening nanoscale structures within an anchoring structure to form a nanostructure composite and nanostructure composites formed therefrom. A primary fluid layer is formed on an anchoring substrate. Nanostructures are provided on an initial substrate, the nanostructures having a defined height and orientation with respect to the initial substrate. The nanostructures are introduced to a desired depth in the primary fluid layer, such that the orientation of the nanostructures relative to the growth substrate is substantially maintained. The primary fluid layer comprises one or more fluid layers. Ones of multiple fluid layers are selected such that when altered to form an anchoring structure, a portion of the anchoring structure can be removed, permitting exposure of at least a portion of the nanostructures from the anchoring structure in which they are affixed. The growth substrate is removed. Ends or other parts of nanostructures may be exposed from the anchoring structure.Type: GrantFiled: May 18, 2011Date of Patent: September 30, 2014Assignee: California Institute of TechnologyInventors: Elijah Bodhi Sansom, Derek Rinderknecht, Morteza Gharib
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Patent number: 8848584Abstract: A time synchronization method in a wireless sensor network, a low power routing method using a reservation scheme, and an apparatus for performing the method are provided. The time synchronization method in the wireless sensor network may include: receiving a first synchronization request command packet from a parent node that manages time synchronization for a predetermined synchronization region; receiving, from the parent node, a second synchronization request command packet that has a transmission timestamp value of the first synchronization request command packet; and performing time synchronization for a child node based on a reception time of the first synchronization request command packet, a reception time of the second synchronization request command packet, and the transmission timestamp value of the first synchronization request command packet.Type: GrantFiled: July 11, 2008Date of Patent: September 30, 2014Assignee: Electronics and Telecommunications Research InstituteInventors: Chang Sub Shin, Gwang Ja Jin, So Young Hwang, Yoonmee Doh, Bong Soo Kim, Cheol Sig Pyo, Jong-Suk Chae
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Patent number: 8844471Abstract: An apparatus for heating water having three vertically aligned water heating process sections. The upper section includes an annular water storage tank disposed around a combustion chamber having a downward firing burner. The intermediate section, disposed vertically below the upper section receives flue gas from the combustion chamber, which flue gas is cooled and dehumidified, producing a hot condensate which collects in a passive condensate flow control device disposed proximate the bottom of the intermediate section. The lower section, disposed vertically below the intermediate and separated therefrom by the passive condensate flow control device receives hot condensate from the flow control device, which is used to preheat and humidify air, such as room air, which is then recycled to the combustion process of the upper section for use as combustion air.Type: GrantFiled: June 14, 2010Date of Patent: September 30, 2014Assignee: Gas Technology InstituteInventors: Paul Eric Glanville, Mark Jacob Khinkis, Aleksandr Pavlovich Kozlov, David Charles Kalensky
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Patent number: 8846066Abstract: Compositions and methods useful in the reduction of localized fat deposits and tightening of loose skin in subjects in need thereof using pharmacologically active detergents are disclosed. The pharmacologically active detergent compositions can additionally include anti-inflammatory agents, analgesics, dispersion or anti-dispersion agents and pharmaceutically acceptable excipients. The pharmacologically active detergent compositions are useful for treating localized accumulations of fat including, for example, lower eyelid fat herniation, lipodystrophy and fat deposits associated with cellulite and do not require surgical procedures such as liposuction.Type: GrantFiled: June 13, 2013Date of Patent: September 30, 2014Assignees: The Regents of the University of California, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical CenterInventors: Michael S. Kolodney, Adam M. Rotunda
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Patent number: 8845445Abstract: A cocking loosening feedback method includes sensing sequential three-dimensional direction information of a golf club and three-dimensional direction information of the arm a user, analyzing the change of an angle between both three-dimensional information with respect to time, generating a cocking loosening evaluation variable based on the difference between the cocking loosening point and the impact point and the difference between the backswing top point and the impact point in the analyzed three-dimensional information, analyzing the evaluation variable based on a predetermined criterion to evaluate the cocking loosening, and providing its feedback information to the user.Type: GrantFiled: September 6, 2012Date of Patent: September 30, 2014Assignee: Korea Institute of Science and TechnologyInventors: Jin Wook Kim, An Jin Park, Hyeong Rae Choi, Sung Kuk Chun, Dong Hoon Kang