Abstract: A bacterial toxin protein such as a Shiga toxin protein is efficiently produced using plant cells. The plant cells are transformed using a DNA construct containing DNA encoding a hybrid protein in which the bacterial toxin proteins such as the Shiga toxin proteins are tandemly linked through a peptide having the following characteristics (A) and (B) to produce the bacterial toxin protein in the plant cells: (A) a number of amino acids is 12 to 30; and (B) a content of proline is 20 to 35%.

Abstract: An optical apparatus comprises a waveguide substrate and an optical reference cavity. The optical reference cavity comprises an optical waveguide formed on the waveguide substrate and arranged to form a closed loop greater than or about equal to 10 cm in length. The RMS resonance frequency fluctuation is less than or about equal to 100 Hz. The Q-factor can be greater than or about equal to 108. The optical waveguide can exhibit optical loss less than or about equal to 0.2 dB/m for propagation of an optical signal along the optical waveguide. The closed loop path can comprise two or more linked spirals greater than or about equal to 1 meter in length and can occupy an area on the waveguide substrate less than or about equal to 5 cm2.

Abstract: The present invention relates to pharmaceutical and food compositions for preventing or treating diabetes or obesity, and more particularly to pharmaceutical compositions and functional foods for preventing or treating diabetes or obesity, which contain, as an active ingredient, a novel compound synthesized from a compound separated from an extract of the Stereocaulon alpinum. The novel compounds of the invention have very excellent PTP-1b (protein tyrosine phosphatase-1b) inhibitory activities, act selectively only on PTP-1b among protein tyrosine phosphatases, and are substantial PTP-1b inhibitors which are effective in preventing or treating diabetes or obesity.

Abstract: In exemplary implementations of this invention, an automultiscopic display device includes (1) one or more spatially addressable, light attenuating layers, and (2) a controller which is configured to perform calculations to control the device. In these calculations, tensors provide sparse, memory-efficient representations of a light field. The calculations include using weighted nonnegative tensor factorization (NTF) to solve an optimization problem. The NTF calculations can be sufficiently efficient to achieve interactive refresh rates. Either a directional backlight or a uniform backlight may be used. For example, the device may have (1) a high resolution LCD in front, and (2) a low resolution directional backlight. Or, for example, the device may have a uniform backlight and three or more LCD panels. In these examples, all of the LCDs and the directional backlight (if applicable) may be time-multiplexed.

Abstract: A heating section 20 having heating elements using carbon which generates heat when a high-frequency electric current is fed to a coil whose pitch can be adjusted as desired is arranged in a heating chamber 10. A cooling chamber 80 configured to cool metal is disposed below the heating chamber 10 in communication with the heating chamber 10 via a connection section 60. A water-cooled vertically movable shaft 90 which is capable of supporting the metal to be heat-treated and entering the heating chamber 10 is disposed so as to penetrate through the bottom portion of the cooling chamber 80. A gas introducing pipe 81 configured to introduce gas for cooling heated metal to be heat-treated supported by the water-cooled vertically movable shaft 90 and moved from the heating chamber 10 to the cooling chamber 80 is disposed in the cooling chamber 80.

Abstract: Provided in one embodiment is a method of forming an inorganic nanowire, comprising: providing an elongated organic scaffold; providing a plurality of inorganic nanoparticles attached to the organic scaffold along a length of the organic scaffold; and fusing the nanoparticles attached to the organic scaffold to form an inorganic nanowire.

Abstract: The present invention provides a method for enrichment and isolation of endogenous transcription factors and their complexes. Also, this invention provides corresponding tandem arrays of concatenated transcription factor response elements (catTFRE). The method employs the property of transcription factors binding to sequence-specific DNA elements during regulation of gene expression. The catTFREs are designed and synthesized as concatenate dual copies of DNA response elements for various transcription factors. The DNA sequence of synthesized catTFRE is cloned to a target vector. Biotinylated catTFRE with 200 bp arms is prepared by PCR strategy. For enrichment and isolation of endogenous transcription factors and their complexes, the biotinylated catTFRE is immobilized to streptavidin-coated magnetic beads and then incubated with nuclear extract. Thereby endogenous transcription factors and their complexes are isolated from nuclear extract.

Abstract: The present invention contemplates induction of immunological tolerance thereby providing permanent allograft acceptance. This method obviates the need for a lifelong regimen of immunosuppressive agents which can increase the risk of infection, autoimmunity, and cancer. Immunological tolerance is thought to be mediated by regulatory T lymphocytes (Treg cells) with immunosuppressive capabilities. A therapeutically relevant platform comprising artificial constructs are contemplated comprising numerous soluble and surface bound Treg cell stimulating factors that may induce tolerance following allograft transplantation. Such artificial constructs, being the size of a cell, have surface bound monoclonal antibodies specific to regulatory T-cell surface moieties and encapsulated soluble regulatory T-cell modulating factors.

Abstract: A data input method of a NAND flash memory includes: determining whether a size of a writing-requested data is less than a reference value; calculating an error correction code (ECC) for the data using a software ECC method when the data size is less than the reference value; and writing the data and the ECC to a data region of the NAND flash memory. A data output method of the NAND flash memory includes: determining whether a size of a reading-requested data is less than a reference value; reading the data and an error correction code (ECC) from the NAND flash memory; calculating an ECC for the read data using a software ECC method when the data size is less than the reference value; and performing an error detection and correction by comparing the calculated ECC and the read ECC.

Abstract: The present invention generally relates to methods and compositions used delivery of gene editing compositions including transcriptional effectors with parvovirus and preferred methods for making same.

Abstract: A uniform external field can enhance condensation on a superhydrophobic surface. Jumping droplets on superhydrophobic surfaces accumulate a positive charge which promises the manipulation and control of jumping behavior using external electric fields.

Abstract: A microscope has a light source for generating a light beam having a wavelength, ?, and beam-forming optics configured for receiving the light beam and generating a Bessel-like beam that is directed into a sample. The beam-forming optics include an excitation objective having an axis oriented in a first direction. Imaging optics are configured for receiving light from a position within the sample that is illuminated by the Bessel-like beam and for imaging the received light on a detector. The imaging optics include a detection objective having an axis oriented in a second direction that is non-parallel to the first direction.

Abstract: The present disclosure relates to a radial and axial flux motor using integrated windings, which includes a rotor which includes a rotor core having a shape of a hollow cylindrical case, and permanent magnets for an inner lateral surface and permanent magnets for a ceiling surface that are coupled to the inner lateral surface and the ceiling surface of the rotor core respectively, and which is rotated about a shaft, and a stator which includes a stator core and windings coupled to the stator core and which is installed in the rotor. Therefore, a radial flux motor and an axial flux motor are integrated into one motor to be able to increase both efficiency and output.

Abstract: A solar-powered concentration unit and method of conducting a solar powered separation are described. An improved method of solar-powered concentration of ethylene glycol is described and exemplified. The invention also includes a mobile distillation/concentration unit that can be placed on a truck and transported to a desired location. A further advantage of the invention is that good separations can be achieved without the use of a selective membrane and/or mechanical pumps.

Abstract: The present invention relates to a field of computer application technology, and more particularly to a computer account management system and a realizing method thereof.

Abstract: Disclosed are a sound virtualization method and apparatus. The sound virtualization method includes generating virtual sound devices, generating virtual audio devices on the basis of an audio device, acquiring a mapping relation between sounds created by the virtual sound device and sounds output by the virtual audio device, acquiring the sounds from memories on the basis of the mapping relation, and outputting the sounds through the virtual audio devices according to the mapping relation. Accordingly, it is possible to provide sound to a plurality of users.

Abstract: A microscope has a light source for generating a light beam having a wavelength, ?, and beam-forming optics configured for receiving the light beam and generating a Bessel-like beam that is directed into a sample. The beam-forming optics include an excitation objective having an axis oriented in a first direction. Imaging optics are configured for receiving light from a position within the sample that is illuminated by the Bessel-like beam and for imaging the received light on a detector. The imaging optics include a detection objective having an axis oriented in a second direction that is non-parallel to the first direction.

Abstract: Methods, compositions, and devices are disclosed which use microRNA to detect, predict, treat, and monitor physiological conditions such as disease or injury. microRNA are isolated and their differential expression is measured to provide diagnostic information. This information may then be utilized for evaluation and/or treatment purposes.

Abstract: Provided is a method and apparatus for managing sensor data by determining an appropriate sensor data collection cycle for each service in view of a weighting such as an amount of energy saved by data collection cycles, a data storage space and data processing time, and a probability of an error happening, and collecting and manage sensor data based on the sensor data collection cycle. The apparatus for managing the sensor data includes a profile management unit to manage a sensor profile defining each senor, a sensor system and a characteristic of a service, a service management unit to manage a preinstalled service and to collect and recommend a service based on the sensor profile from the sensor system, and a data collection cycle determination unit to determine a necessary sensor data collection cycle for the service.

Abstract: Systems and methods are disclosed herein for quantitatively identifying a patient's physiological state based on one or more capnograms. One or more capnograms are acquired, each capnogram being associated with a patient and including one or more respiratory cycles, and one or more features from the one or more respiratory cycles are extracted. One or more classifiers are provided based on the one or more extracted features, and each classifier is used to select a physiological state from one or more candidate physiological states for each of the one or more respiratory cycles. For each of the selected physiological states, a likelihood value is determined, and a physiological state of the patient is determined based on the likelihood values.