Abstract: A needle assembly that has a flexible shield movable between (i) a first position, where the flexible shield is uncompressed, and (ii) a second position, where the flexible shield is compressed and an administering member located within the flexible shield, where at least one of the administering member and the flexible shield is axially movable with respect to the other of the administering member and the flexible shield in an unlocked position prior to and during usage of the needle assembly, and the at least one of the administering member and the flexible shield is no longer axially movable with respect to the other of the administering member and the flexible shield in a locked position. Prior, during and after use of the needle assembly, the needle is never exposed. After a single usage of the needle assembly, the needle is locked within the flexible shield and cannot be reused.

Abstract: The present invention is directed to a method of inhibiting CD1d activation by administering a composition containing a moiety that blocks CD1d activation. Compositions of the invention are useful for the attenuation of CD1d-restricted immune responses, including treatment of skin disorders due to hyperactive immune responses (e.g., contact hypersensitivity), for systemic administration to attenuate ongoing immune responses, and to provide hypoallergenic cosmetic products including pharmaceutical, cosmetic, and skin care compositions. Preferably, these compositions are in a form intended for topical administration.

Abstract: The present invention is directed to nucleic acid and amino acid sequences of a novel piggyBac transposase enzymes created by modifying the transposase of Trichoplusia ni. The piggyBac transposases of the present invention are functionally active or hyperactive for excision and have decreased integration activity compared to wild type Trichoplusia ni piggyBac transposase enzyme. These transposases are ideal for use in methods of transforming cells and organisms. In particular embodiments, the present invention provides methods of transient integration and expression of transgenes.

Abstract: A wireless link apparatus includes a plurality of antennas; a signal detector configured to calculate SNR based on a signal received from at least one of the plurality of antennas; and a mode selector configured to determine the number of an antenna to be used in modulation method and signal transmission by comparing the calculated SNR with a preset critical value. Further, the wireless link apparatus includes a transmitter configured to modulate a signal in the modulation method determined by the mode selector and transmit the modulated signal using an antenna corresponding to the determined number of the antennas.

Abstract: An extrusion apparatus and process are disclosed that produce high-performance extrusion structures. The extrusion apparatus includes a shear tool that applies a rotational shear force and an axial extrusion force to the face of a billet material that plasticizes the billet material. Plasticized material is extruded through an extrusion die along the length of the inner bore of the shear tool which yields hollow and solid extrusion structures. The process refines the microstructures of the extrusion structures and extrusion materials.

Abstract: The invention provides an efficient multiplex method for identifying binding partners of small molecules and proteins. The small molecules and proteins are tagged with a nucleic acid barcode that can be used to identify the protein or small molecule, and thereby its partner.

Abstract: A microscope has a light source for generating a light beam having a wavelength, ?, and beam-forming optics configured for receiving the light beam and generating a Bessel-like beam that is directed into a sample. The beam-forming optics include an excitation objective having an axis oriented in a first direction. Imaging optics are configured for receiving light from a position within the sample that is illuminated by the Bessel-like beam and for imaging the received light on a detector. The imaging optics include a detection objective having an axis oriented in a second direction that is non-parallel to the first direction.

Abstract: The present invention provides a method for manufacturing a large-area film, the method comprising the steps of: dispersing various fine particles in a polar solvent to prepare a dispersion; adding water to the dispersion to prepare a mixture; and adding an organic solvent capable of generating Rayleigh-Benard convection to the mixture to induce the interfacial assembly of the fine particles, thereby forming the film. The invention also provides a large-area film manufactured by the method. According to the invention, a large-area, high-purity film can be quickly manufactured by a simple solution process, and the manufactured large-area film has excellent physical and electrical properties, and thus can be used in various applications.

Abstract: A DNA analysis system that controls DNA analysis by wireless using an application of a mobile device and a very small DNA analysis apparatus, and that receives a DNA analysis result in real time on the spot is provided. Therefore, by performing DNA analysis by simultaneously controlling a plurality of small DNA analysis apparatuses using signal processing and screen display functions of a mobile device, analysis speed of DNA is improved, and an analysis result of DNA can be provided in real time. Further, by forming a DNA analysis apparatus in a very small size, DNA can be immediately analyzed with low power consumption on the spot using a small sample, and the DNA analysis apparatus can be carried.

Abstract: A MEMS apparatus comprising composite vibrating unit and the manufacturing method thereof are disclosed. The vibrating unit includes a stiffness element on which a first material is disposed. A second material being a conductive material is disposed on the first material and is extended to the stiffness element to remove electric charge on first material. When a temperature is changed, a variation direction of a Young's modulus of the first material is opposite to a variation direction of a Young's modulus of the stiffness element. The unique attributes above allow vibrating unit of the MEMS apparatus such as resonator and gyroscope to have stable resonance frequency against the change of temperature.

Abstract: A fiber media and a filter device. The fiber media has a plurality of nanofibers formed of a polymer material, having diameters less than 1 micron, and formed into a fiber mat. A barrier layer is disposed on the nanofibers to prevent dissolution of the nanofibers in the fiber mat upon exposure of the fiber mat to a solvent of the polymer material. The barrier layer coated nanofibers have a maximum strain before breakage of at least 2%. The filter device includes the fiber media and a support attached to the fiber mat.

Abstract: Compositions and methods of increasing autophagy in a cell, or population of cells are disclosed. The methods generally include contacting the cell or cells with an effective amount of an agent that increases the bioavailability of an active isoform of SDF-1. Exemplary agents include active SDF-1 polypeptides, metformin, and DPP4 inhibitors. The methods can include administering the agent to a subject, or treating cells in vivo, in vitro or ex vivo. In some embodiments, cells are treated ex vivo and then transplanted into a subject. In a preferred embodiment, the cells are mesenchymal stem cells such as those found in bone marrow. The compositions and methods can be utilized in a number of therapeutic applications including increasing the longevity or survival of a graft or transplant, increasing the rate of recovery from an injury, reducing one or more symptoms of a chronic inflammatory disease and reducing effect associated with aging.

Abstract: Provided are a system and method of simultaneously providing stereoscopic images to multiple users. The system includes at least one glasses unit, a stereoscopic image generating device configured to calculate spatial information of the at least one glasses unit, and generate the stereoscopic image corresponding to the spatial information of the at least one glasses unit, and a stereoscopic image providing device configured to project the stereoscopic image corresponding to the spatial information of the at least one glasses unit to provide the projected stereoscopic image to the at least one glasses unit. Thus, through lightweight glasses constituted of only simple optical elements without a separate electronic device such as a micro panel, stereoscopic information such as through an existing HMD may be provided to multiple users.

Abstract: Disclosed are methods for producing chalcopyrite compound (e.g., copper indium selenide (CIS), copper indium gallium selenide (CIGS), copper indium sulfide (CIS) or copper indium gallium sulfide (CIGS)) thin films. The methods are based on solution processes, such as printing, particularly, multi-stage coating of pastes or inks of precursors having different physical properties. Chalcopyrite compound thin films produced by the methods can be used as light-absorbing layers for thin-film solar cells. The use of the chalcopyrite compound thin films enables the fabrication of thin-film solar cells with improved efficiency at low costs.

Abstract: A method includes transferring a general query message to managers of a mobility control server in response to receiving, from a router, the general query message for detecting a mobile node that requested to receive multicast data; storing, in a multicast mapping table, an address of the mobile node that requested to receive the multicast data when a membership report message of the mobile node is received from at least one of the managers and transferring the membership report message to the router; and forming a tunnel between the router and a manager that transfers the membership report message.

Abstract: Disclosed is a method of manufacturing a field effect type compound semiconductor device in which leakage current of a device is decreased and breakdown voltage is enhanced.

Abstract: Burst quality of service (QoS) mode uses a higher modulation rate and coding scheme for transmitting data blocks in a short period of time between a transmitting terminal and a user terminal experiencing a channel state above a certain threshold in a wireless communication system. Burst QoS may reduce data transmission time, thereby achieving a higher level of channel efficiency as well as a reduction in the consumption of power. In burst QoS mode, the channel state information (CSI) may be repeatedly measured. When the CSI is above a certain threshold, a higher rate modulation and coding (MC) scheme is used for burst data transmission. After the burst, a short sleep is triggered to reduce power consumption.

Abstract: The present invention features a method for determining the prognosis for survival of a cancer patient. Methods for measuring the level of NOL3 expression in a cancer cell-containing sample from a patient, and comparing the level of NOL3 expression in the sample to a reference level of NOL3 expression are also included. A higher level of NOL3 relative to the reference level correlates with decreased survival of the patient, and an equivalent or lower level of NOL3 relative to the reference level correlates with increased survival of the patient.

Abstract: A method for raising the resolving power, specificity, and peak capacity of conventional ion mobility spectrometry is disclosed. Ions are separated in a dynamic electric field comprising an oscillatory field wave and opposing static field, or at least two counter propagating waves with different parameters (amplitude, profile, frequency, or speed). As the functional dependencies of mean drift velocity on the ion mobility in a wave and static field or in unequal waves differ, only single species is equilibrated while others drift in either direction and are mobility-separated. An ion mobility spectrum over a limited range is then acquired by measuring ion drift times through a fixed distance inside the gas-filled enclosure. The resolving power in the vicinity of equilibrium mobility substantially exceeds that for known traveling-wave or drift-tube IMS separations, with spectra over wider ranges obtainable by stitching multiple segments.

Abstract: Disclosed is a method for manufacturing an oxide thin film transistor, including: forming a gate electrode on a substrate on which a buffer layer is formed; forming a gate insulation layer on an entire surface of the substrate on which the gate electrode is formed; forming an oxide semiconductor layer on the gate insulation layer; forming a first etch stop layer on the oxide semiconductor layer; forming a second etch stop layer on the first etch stop layer by an atomic layer deposition method; patterning the first etch stop layer and the second etch stop layer, or forming a contact hole, through which a part of the oxide semiconductor layer is exposed, in the first etch stop layer and the second etch stop layer; forming a source electrode and a drain electrode on the first etch stop layer and the second etch stop layer; and forming a passivation layer on the entire surface of the substrate on which the source electrode and the drain electrode are formed.