Patents Assigned to INSTITUTE
  • Patent number: 8754040
    Abstract: Provided are: a novel compound having a structure different from that of existing drugs; a novel microorganism capable of producing the novel compound; and further; a novel compound effective to a multiple-drug-resistant bacterium. To provide a novel compound having a high therapeutic effect which can be expected to have a low hurdle for practical realization by selecting an intended compound from many candidate compounds based not only on an antibacterial activity but also on evaluation including a therapeutic effect, a cyclic peptide compound shown by the following formula (1) or a pharmaceutically allowable salt thereof and a microorganism with Accession No. NITE BP-870 or a microorganism mutated naturally or artificially therefrom are provided. (In the formula (1), R1 represents an acyl group having 7, 8, or 9 carbon atoms and optionally containing a substituent group; R2 represents a methyl group or a hydrogen atom; and R3 represents an ethyl group or a methyl group.
    Type: Grant
    Filed: May 25, 2011
    Date of Patent: June 17, 2014
    Assignees: Genome Pharmaceuticals Institute Co., Ltd., The University of Tokyo
    Inventors: Kazuhisa Sekimizu, Hiroshi Hamamoto, Kazuhisa Murakami
  • Patent number: 8754323
    Abstract: A dye-sensitized solar cell is provided, wherein it can be produced by a relatively easy and simple process and ensures high conversion efficiency even in cases where the thickness of the porous semiconductor layer is increased. The dye-sensitized solar cell 10 includes, in the interior of or on the conductive-substrate-side surface of the porous semiconductor layer 16, conductive metal film 20, such as a film of tungsten, having a large number of randomly located penetrations 24. Penetrations 24 of the conductive metal film 20 are formed by forming a fine-particle layer on the surface of the porous semiconductor layer, forming a conductive metal film on the surface of the fine-particle layer, and making the fine-particle layer disappear by heating or solvent-cleaning.
    Type: Grant
    Filed: June 21, 2007
    Date of Patent: June 17, 2014
    Assignees: National University Corporation Kyushu Institute of Technology, Nippon Steel & Sumikin Chemical Co., Ltd.
    Inventors: Shuzi Hayase, Ryuichi Shiratsuchi, Suehiro Ohkubo, Yoshihiro Yamaguchi
  • Patent number: 8756544
    Abstract: A method for inserting characteristic extractor is provided. The method includes parsing a transaction level model (TLM) of an electronic device of a target system to find out at least one target point of an operation status of the electronic device; and inserting at least one characteristic extractor into the at least one target point.
    Type: Grant
    Filed: March 26, 2013
    Date of Patent: June 17, 2014
    Assignee: Industrial Technology Research Institute
    Inventors: Yi-Siou Chen, Tung-Hua Yeh, Jen-Chieh Yeh, Wen-Tsan Hsieh
  • Patent number: 8755876
    Abstract: Methods and systems for automatic detection of Atrial Fibrillation (AF) are disclosed. The methods and systems use time-varying coherence functions (TVCF) to detect AF. The TVCF is estimated by the multiplication of two time-varying transfer functions (TVTFs).
    Type: Grant
    Filed: November 26, 2012
    Date of Patent: June 17, 2014
    Assignee: Worcester Polytechnic Institute
    Inventors: Ki H. Chon, Jinseok Lee
  • Patent number: 8754237
    Abstract: In recognition of the need to develop novel therapeutic agents and efficient methods for the synthesis thereof, the present invention provides novel bifunctional, trifunctional, or multifunctional compounds for inhibiting histone deacetylases, and pharmaceutically acceptable salts and derivatives thereof. The present invention further provides methods for treating disorders regulated by histone deacetylase activity (e.g., proliferative diseases, cancer, inflammatory diseases, protozoal infections, hair loss, etc.) comprising administering a therapeutically effective amount of an inventive compound to a subject in need thereof. The present invention also provides methods for preparing compounds of the invention.
    Type: Grant
    Filed: July 16, 2012
    Date of Patent: June 17, 2014
    Assignees: President and Fellows of Harvard College, Dana-Farber Cancer Institute, Inc.
    Inventors: James Elliot Bradner, Ralph Mazitschek, Weiping Tang, Stuart L. Schreiber
  • Patent number: 8756207
    Abstract: In accordance with the teachings described herein, systems and methods are provided for identifying potential duplicate entries in a database. Matchcodes are generated for a plurality of records, wherein a matchcode for a record may be generated by: receiving a character string from the record; determining whether the character string includes a non-essential character substring; if the non-essential character substring is missing from the character string, then generating the matchcode from the character string and adding a wildcard character to the matchcode in place of the missing non-essential character substring. The matchcodes for the plurality of records may be compared to identify matching pairs of matchcodes, wherein for the purpose of identifying a matching pair of matchcodes, two characters are considered the same if they are equal or if one or both are wildcard characters.
    Type: Grant
    Filed: November 18, 2011
    Date of Patent: June 17, 2014
    Assignee: SAS Institute Inc.
    Inventor: Brian Carl Rineer
  • Patent number: 8752415
    Abstract: The present invention relates to a method of measuring engine oil deterioration, including measuring the first absorbance of engine oil using near infrared at a wavelength of 1000 nm or more, measuring the second absorbance of the engine oil during use using near infrared at the wavelength, and comparing the first absorbance and the second absorbance of the engine oil, so that the engine oil may be determined to be in a state of deterioration when the second absorbance may be at least 1.5 times the first absorbance, and to a system for measuring engine oil deterioration therefor.
    Type: Grant
    Filed: December 11, 2011
    Date of Patent: June 17, 2014
    Assignees: Hyundai Motor Company, Korea Research Institute of Chemical Technology
    Inventors: Won Gyu Kim, Ki Hwan Oh, Keun Woo Chung, Young-Wun Kim
  • Patent number: 8754198
    Abstract: The present invention relates to microorganisms that express, or have attached to their surface, a TNF? binding polypeptide. Peptides expressed or attached on the surface of microorganism are more resistant to chemical and enzymatic degradation in the gastrointestinal tract. Such microorganisms are capable of binding TNF? and therefore reducing the content of free TNF? and alleviating its pro-inflammatory effects in the gut. The invention also relates to the use of such microorganisms as medicament in the treatment of inflammatory bowel disease.
    Type: Grant
    Filed: January 5, 2011
    Date of Patent: June 17, 2014
    Assignees: University of Ljubljana, Institute Jozef Stefan, Labena d.o.o.
    Inventors: Mojca Lunder, Matjaz Ravnikar, Borut Strukelj, Ales Berlec, Boris Ceh
  • Patent number: 8754772
    Abstract: A non-contact vital sign sensing system including a vital sign sensing module and at least one body movement interference cancellation module is provided. The vital sign sensing module and the at least one body movement interference cancellation module are under a self-injection locking (SIL) mode. The vital sign sensing module senses an isotropic vital sign of a body. A mutual injection locking (MIL) mode is achieved between the vital sign sensing module and the at least one body movement interference cancellation module to sense the anisotropic body movement signal and to cancel the body movement interference.
    Type: Grant
    Filed: April 26, 2012
    Date of Patent: June 17, 2014
    Assignees: Industrial Technology Research Institute, National Sun Yat-Sen University
    Inventors: Tzyy-Sheng Horng, Fu-Kang Wang, Kang-Chun Peng
  • Patent number: 8755647
    Abstract: A frequency-chirped nano-antenna provides efficient sub-wavelength vertical emission from a dielectric waveguide. In one example, this nano-antenna includes a set of plasmonic dipoles on the opposite side of a SiYV4 waveguide from a ground plane. The resulting structure, which is less than half a wavelength long, emits a broadband beam (e.g., >300 nm) that can be coupled into an optical fiber. In some embodiments, a diffractive optical element with unevenly shaped regions of high- and low-index dielectric material collimates the broadband beam for higher coupling efficiency. In some cases, a negative lens element between the nano-antenna and the diffractive optical element accelerates the emitted beam's divergence (and improves coupling efficiency), allowing for more compact packaging.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: June 17, 2014
    Assignee: Massachusetts Institute of Technology
    Inventors: Ami Yaacobi, Brad Gilbert Cordova, Jie Sun, Michael Watts
  • Patent number: 8754963
    Abstract: Processing images of a scene taken with different focus includes, for each of at least some of the images, determining at least one portion of the image having a predetermined characteristic. A representation of the scene is generated that includes an array of elements, where each of at least some of the elements corresponds to a determined portion of at least one of the images. An element of the array is based on a correspondence between a distance associated with a determined portion of at least one image and a focused distance associated with at least one image. The generated representation is stored or provided as output.
    Type: Grant
    Filed: February 25, 2013
    Date of Patent: June 17, 2014
    Assignee: Massachusetts Institute of Technology
    Inventor: Jae S. Lim
  • Patent number: 8755903
    Abstract: The present invention discloses a functional electrical stimulation system comprising a primary power, a boost module, an energy storage section, an output control relay, an automatic discharge circuit, a foot/hand controlled switch, a current detection chip and a current limiting fuse. The boost module comprises n DC chopper circuits connected in series, and outputs a high voltage of 100-200V. According to an enable signal and a current detection signal, the output control relay disables/enables the DC boost module. The automatic discharge circuit discharges capacitance of the energy storage section automatically when the relay turns off the power input. The Foot/hand controlled switch, the current detection chip and the current limiting fuse form a triple accident protection circuit. The functional electrical stimulation system maximizes the intensity of electrical stimulation within the range that the human body can withstand.
    Type: Grant
    Filed: June 28, 2011
    Date of Patent: June 17, 2014
    Assignee: Institute of Automation, Chinese Academy of Sciences
    Inventors: Zengguang Hou, Min Tan, Yixiong Chen, Pengfeng Li, Hongbo Wang, Long Cheng, Guoqing Hu, Qingling Li, Feng Zhang, Jin Hu, Xinchao Zhang, Yi Hong, Junwei Zhang, Jinzhu Bai, Zhen Lv
  • Patent number: 8753327
    Abstract: The present invention relates to methods for treating obstructive sleep apnea (OSA), alleviating a negative OSA symptom, reducing snoring, or improving quality of life in a subject, comprising administering to the subject an effective amount of a pharmaceutical composition comprising pyridostigmine before sleep. Also provided are related medicaments as well as methods for preparing the medicaments.
    Type: Grant
    Filed: January 27, 2012
    Date of Patent: June 17, 2014
    Assignee: Pfantastic Medical Research Institute, LLC
    Inventor: Jian-Qiang Fan
  • Patent number: 8754813
    Abstract: An apparatus for protecting a human body from electromagnetic waves includes: a radiator including an antenna; and a periodic structure that is combined with the radiator to form a radiation unit and has a plurality of unit cells periodically arranged, wherein each of the unit cells of the periodic structure contains a ground layer; an electromagnetic bandgap (EBG) board formed on the ground layer and serving as a dielectric spacer; and an EBG pattern made of metal and formed on the EBG board.
    Type: Grant
    Filed: September 23, 2011
    Date of Patent: June 17, 2014
    Assignee: Electronics and Telecommunications Research Institute
    Inventor: Sang il Kwak
  • Patent number: 8753492
    Abstract: An electrochemical system with reduced limiting-current behavior is disclosed. The electrochemical system is useful for fuel cells and bio-sensors. In part, the invention relates a method of reducing or eliminating limiting-current behavior in the operation electrochemical systems, in particular those with ion-selective membrane or electrochemical electrodes, by spatially reducing the convection near the membrane or the electrode. The invention further relates to electrochemical systems in which micropores, microarrays or pillar arrays are used to reduce convection in comparison to conventional systems without microarrays, micropores or pillar arrays.
    Type: Grant
    Filed: June 17, 2011
    Date of Patent: June 17, 2014
    Assignee: Massachusetts Institute of Technology
    Inventors: Sung Hee Ko, Sung Jae Kim, Jongyoon Han, HiongYap Gan
  • Patent number: 8755275
    Abstract: A system for managing resources in a communication system including systems, which do not have a permission for a first frequency band, includes coexistence managers configured to, when a frequency band available for the systems is searched from the first frequency band, manage the systems for coexistence and frequency sharing of the systems in the available frequency band; a coexistence enabler configured to transmit and receive information of the systems and information of the coexistence managers; and a coexistence discovery and information server configured to support control of the coexistence managers over the systems, wherein predetermined messages are transmitted and received among the coexistence discovery and information server, the coexistence managers and the coexistence enabler to perform a registration procedure, a coexistence information gathering procedure, a coexistence decision making procedure, a reconfiguration procedure, a management procedure and an event procedure, for the coexistence a
    Type: Grant
    Filed: December 29, 2011
    Date of Patent: June 17, 2014
    Assignee: Electronics and Telecommunications Research Institute
    Inventors: Hyunduk Kang, Dong-Hun Lee
  • Patent number: 8754806
    Abstract: A pulse radar receiver includes a power splitter configured to split a transmit (TX) trigger signal for generating a TX pulse, a phase-locked loop (PLL) configured to receive a division ratio and the TX trigger signal split by the power splitter, and generate a sampling frequency, and a sampler configured to sample a reflected wave received through an RX antenna, according to the sampling frequency generated by the PLL. Accordingly, it is possible to provide a high distance resolution by generating a sampling frequency with a difference from a TX pulse to sample a reflected wave received through an RX antenna. Thus, it is possible to overcome a limitation in the distance resolution due to the pulse width and to measure a minute movement at a short distance. Therefore, the pulse radar receiver is applicable to high range resolution radar applications such as a living body measuring radar.
    Type: Grant
    Filed: December 9, 2011
    Date of Patent: June 17, 2014
    Assignee: Electronics and Telecommunications Research Institute
    Inventors: Pil Jae Park, Seong Do Kim, Sung Chul Woo, Hyun Kyu Yu
  • Patent number: 8754371
    Abstract: A miniature, low cost mass spectrometer capable of unit resolution over a mass range of 10 to 50 AMU. The mass spectrometer incorporates several features that enhance the performance of the design over comparable instruments. An efficient ion source enables relatively low power consumption without sacrificing measurement resolution. Variable geometry mechanical filters allow for variable resolution. An onboard ion pump removes the need for an external pumping source. A magnet and magnetic yoke produce magnetic field regions with different flux densities to run the ion pump and a magnetic sector mass analyzer. An onboard digital controller and power conversion circuit inside the vacuum chamber allows a large degree of flexibility over the operation of the mass spectrometer while eliminating the need for high-voltage electrical feedthroughs. The miniature mass spectrometer senses fractions of a percentage of inlet gas and returns mass spectra data to a computer.
    Type: Grant
    Filed: February 14, 2012
    Date of Patent: June 17, 2014
    Assignee: The Massachusetts Institute of Technology
    Inventors: Ian W. Hunter, Brian D. Hemond, Harold F. Hemond
  • Patent number: 8753285
    Abstract: An ECG sensing apparatus and a method for removing a baseline drift in the clothing are provided. The ECG sensing apparatus filters ECG signals and filters a baseline drift noise which is caused by human body's motion and breathing. Accordingly, the baseline drift in the sensing apparatus is minimized even if there is a free motion.
    Type: Grant
    Filed: September 12, 2013
    Date of Patent: June 17, 2014
    Assignee: Korea Electronics Technology Institute
    Inventors: Young Hwan Kim, Jae Gi Son, Dong Sun Kim, Seung Chul Lee
  • Patent number: 8753504
    Abstract: A system and process are disclosed for removing elemental sulfur compounds from hydro-desulfurization (HDS) treated hydrocarbon products including liquid hydrocarbon fuels. Low (sub-ppm) concentrations of sulfur remain in the hydrocarbons, providing, e.g., fuel products suitable for use in various modalities including, e.g., jet fuels and fuel cell Auxiliary Power Units (APUs).
    Type: Grant
    Filed: April 28, 2011
    Date of Patent: June 17, 2014
    Assignee: Battelle Memorial Institute
    Inventors: Gregory A. Whyatt, Liyu Li