Patents Assigned to INSTITUTE
  • Patent number: 12257287
    Abstract: Provided are a polypeptide derivative, modified derivative or salt thereof, and use of the polypeptide derivative, modified derivative or salt thereof, wherein the polypeptide derivative, modified derivative or salt thereof comprises a polypeptide having the sequence of following general formula I, general formula I: HX2QGTFTSDX10SX12YLX15X16X17X18AX20 EFX23X24WLX27X28X29X30X31, wherein the definitions of X2, X10, X12, X15, X16, X17, X18, X20, X23, X24, X27, X28, X29, X30 and X31 are consistent with the definitions in the claims and the description. The polypeptide derivative provided by the invention has a dual agonistic effect on GC/GLP-1 receptors, so that a synergistic effect on energy metabolism is generated, which can effectively reduce blood glucose while reducing body weight and improving the body fat level, and the efficacy is better than that of a single GLP-1 receptor agonist.
    Type: Grant
    Filed: November 12, 2019
    Date of Patent: March 25, 2025
    Assignee: Tianjin Institute of Pharmaceutical Research Co., Ltd.
    Inventors: Yingmei Han, Wei Liu, Bingni Liu, Weiling Kong, Naxia Zhao, Guangping Xia, Qian Shang, Xiaohua Kong, Jing Jin, Yuquan Li, Xuyuan Liu
  • Patent number: 12258440
    Abstract: Embodiments of the invention relate to a novel class of polymers with superior mechanical properties and chemical stability, as compared to known polymers. These polymers are particularly well suited for use in anion exchange membranes (AEMs), including those employed in fuel cells. Novel methods for the manufacture of these polymers are also described.
    Type: Grant
    Filed: October 24, 2023
    Date of Patent: March 25, 2025
    Assignee: Rensselaer Polytechnic Institute
    Inventors: Chulsung Bae, Woo-Hyung Lee
  • Patent number: 12257312
    Abstract: The present invention relates to polymer conjugates. More specifically, the present invention relates to polymer conjugates capable of binding to fungi, to compositions comprising these conjugates and to the use of these conjugates for detecting the presence of fungi in a sample such as, for example, a biological sample. The present invention also provides for the use of said polymer conjugates in the treatment of a fungal infection.
    Type: Grant
    Filed: May 17, 2019
    Date of Patent: March 25, 2025
    Assignees: HYDERABAD EYE INSTITUTE, UNIVERSITY OF BRADFORD, UNIVERSITY OF SHEFFIELD
    Inventors: Prashant Garg, Stephen Rimmer, Charles William Ian Douglas
  • Patent number: 12258323
    Abstract: The present invention provides dihydrooxydiazinone compounds of general formula (I): in which R1, R2, R3, and R4, are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative diseases, as a sole agent or in combination with other active ingredients.
    Type: Grant
    Filed: July 11, 2022
    Date of Patent: March 25, 2025
    Assignees: Bayer Aktiengesellschaft, Bayer Pharma Aktiengesellschaft, The Broad Institute, Inc., Dana-Farber Cancer Institute, Inc.
    Inventors: Manuel Ellermann, Stefan Nikolaus Gradl, Charlotte Christine Kopitz, Martin Lange, Adrian Tersteegen, Philip Lienau, Christa Hegele-Hartung, Detlev Sülzle, Timothy A. Lewis, Heidi Greulich, Xiaoyun Wu, Matthew Meyerson, Alex Burgin
  • Patent number: 12260637
    Abstract: The application discloses a classification method and a system of UAV hyperspectral vegetation species based on a deep learning, where the method includes the following steps: collecting hyperspectral images by a UAV; preprocessing collected hyperspectral images to obtain preprocessed images, and performing a stitching mosaicking preprocessing on the preprocessed images to obtain hyperspectral orthoimages; labeling the hyperspectral orthoimages to obtain a label data set; performing a vegetation index fusion on the hyperspectral orthoimages to obtain vegetation index-hyperspectral orthoimages; constructing a grassland vegetation classification model based on the vegetation index-hyperspectral orthoimages and the label data set, and completing a vegetation species classification by using the grassland vegetation classification model.
    Type: Grant
    Filed: April 19, 2024
    Date of Patent: March 25, 2025
    Assignee: Institute of Mountain Hazards and Environment, Chinese Academy of Sciences
    Inventors: Hui Zhao, Jundi Wang, Xiaodan Wang, Da Wei, Yaohua Luo
  • Publication number: 20250097460
    Abstract: An image encoding method according to the present disclosure may include generating an atlas based on a plurality of viewpoint images; encoding the atlas; and encoding metadata for the atlas. In this case, the metadata may include data of a patch packed in the atlas, and the patch data may include type information of an entity corresponding to a patch.
    Type: Application
    Filed: September 13, 2024
    Publication date: March 20, 2025
    Applicant: Electronics and Telecommunications Research Institute
    Inventors: Kwan-Jung OH, Gwangsoon LEE, Hong-Chang SHIN, Jun-Young JEONG
  • Publication number: 20250097584
    Abstract: A method of decoding an image, includes obtaining at least one offset for a picture, deriving a variable for scaling for the picture based on the at least one offset, and performing inter prediction based on the variable for scaling for the picture. The at least one offset is defined with a direction of scaling.
    Type: Application
    Filed: November 29, 2024
    Publication date: March 20, 2025
    Applicant: B1 INSTITUTE OF IMAGE TECHNOLOGY, INC.
    Inventor: Ki Baek KIM
  • Publication number: 20250096316
    Abstract: Provided are a wound-type all-solid-state lithium ion secondary battery including a laminate in which a positive electrode layer, a solid electrolyte layer, and a negative electrode layer are arranged in this order, the laminate being wound around a core material, in which the solid electrolyte layer contains an amorphous solid electrolyte which contains a lithium-containing oxide containing Li, B, and O and a lithium salt, and in the amorphous solid electrolyte, a value of a ratio of a content of the lithium salt to a content of the lithium-containing oxide is 0.001 to 1.5 in terms of a molar ratio; and a manufacturing method of the wound-type all-solid-state lithium ion secondary battery.
    Type: Application
    Filed: November 28, 2024
    Publication date: March 20, 2025
    Applicants: FUJIFILM Corporation, INSTITUTE OF SCIENCE TOKYO
    Inventors: Yosuke SHIRATORI, Shintaro YASUI, Yasuharu SHIRAISHI, Kengo SAITO, Kenta WATANABE, Akihiro TAKAHASHI
  • Publication number: 20250092250
    Abstract: A resin composition contains a thermoplastic resin and cellulose fibers, in which a raw material of a main component of the cellulose fibers is a low basis weight paper that has been subjected to a drying step and that has a basis weight of 100 g/m2 or less.
    Type: Application
    Filed: May 11, 2023
    Publication date: March 20, 2025
    Applicants: NIPPON PAPER INDUSTRIES CO., LTD., KYOTO MUNICIPAL INSTITUTE OF INDUSTRIAL TECHNOLOGY AND CULTURE
    Inventors: Yujiroh FUKUDA, Io KAKUTA, Takashi DATE, Fuminari NONOMURA, Takeshi SEMBA, Akihiro ITO, Hiroki NOGUCHI, Kazuo KITAGAWA
  • Publication number: 20250093320
    Abstract: The present application provides a method for estimating abundance and distribution features of antibiotic resistance genes (ARGs) in surfacial sediments of lake and reservoir, including step 1 of obtaining an annual input total of nitrogen and phosphorus pollutants of each tributary flowing into the lake and reservoir; step 2 of constructing a linear regression equation between the abundance of each type of ARGs and the nitrogen and phosphorus discharge; and step 3 of calculating annual input total of nitrogen and phosphorus pollutants to be estimated for each geographical location of the lake and reservoir using inverse distance weighting interpolation analysis based on the annual input total of the nitrogen and phosphorus pollutants obtained in step 1, and substituting the calculated annual input total into the linear regression equation to estimate the abundance of each type of ARGs and analyze a distribution feature of the ARGs.
    Type: Application
    Filed: December 28, 2022
    Publication date: March 20, 2025
    Applicant: CHANGJIANG RIVER SCIENTIFIC RESEARCH INSTITUTE
    Inventors: Li LIN, Xiong PAN, Lei DONG, Huan LI
  • Publication number: 20250098218
    Abstract: A thin film transistor includes a first gate electrode on a substrate, a gate insulating film on the first gate electrode, a first active layer on the gate insulating film, a drain electrode on one side of the first active layer, a sidewall spacer on a side wall of the drain electrode, and a first source electrode provided on the other side of the first active layer and a sidewall of the sidewall spacer.
    Type: Application
    Filed: July 2, 2024
    Publication date: March 20, 2025
    Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Jae-Eun PI, Seung Youl KANG, Yong Hae KIM, Joo Yeon KIM, Hee-ok KIM, Jaehyun MOON, Jong-Heon YANG, Himchan OH, Seong-Mok CHO, Ji Hun CHOI, Chi-Sun HWANG
  • Publication number: 20250092070
    Abstract: The present disclosure provides cyclic silyl ethers of the formula: and salts thereof. The cyclic silyl ethers may be useful as monomers for preparing polymers. Also described herein are polymers prepared by polymerizing a cyclic silyl ether and optionally one or more additional monomers. The polymers may be degradable (e.g., biodegradable). One or more O—Si bonds of the polymers may be the degradation sites. Also described herein are compositions and kits including the cyclic silyl ethers or polymers; methods of preparing the polymers; and methods of using the polymers, compositions, and kits.
    Type: Application
    Filed: January 2, 2024
    Publication date: March 20, 2025
    Applicant: Massachusetts Institute of Technology
    Inventors: Jeremiah A. Johnson, Peyton Shieh, Wenxu Zhang
  • Publication number: 20250094003
    Abstract: The present disclosure provides a method for recognizing a material, an interactive board, and a storage medium, which is applied to an interactive board, and the interactive board includes an operation panel, an infrared touch sensor, and an elastic wave sensor. The infrared touch sensor is arranged on at least one edge of the operation panel to form a touch detection region of the interactive board, and the elastic wave sensor is configured to detect vibration of the operation panel and generate an electrical signal.
    Type: Application
    Filed: December 5, 2024
    Publication date: March 20, 2025
    Applicants: GUANGZHOU SHIYUAN ELECTRONIC TECHNOLOGY COMPANY LIMITED, GUANGZHOU SHIYUAN ARTIFICIAL INTELLIGENCE INNOVATION RESEARCH INSTITUTE CO., LTD.
    Inventors: Fei WANG, Cai CHEN, Jianxin LIN
  • Publication number: 20250097593
    Abstract: This application provides a chip, a dynamic vision sensor, and a method for outputting pixel information. The chip includes a pixel array and a processing circuit, and each pixel row in the pixel array includes at least two pixel groups. In the processing circuit, based on a change of a light intensity value of at least one pixel in a first pixel group, a first signal including row location information of the first pixel group in the pixel array is generated, and a second signal including column location information of a pixel row in which the first pixel group is located is generated. The first signal and the second signal are sent to a pixel output circuit, to enable the pixel output circuit to accurately output location information of the first pixel group whose light intensity value changes in the pixel array.
    Type: Application
    Filed: November 27, 2024
    Publication date: March 20, 2025
    Applicants: HUAWEI TECHNOLOGIES CO., LTD., Institute of Semiconductors,Chinese Academy of Sciences
    Inventors: Ziyang Zhang, Yaoyuan Wang, Liyuan Liu, Lei Kang, Jianxing Liao, Ying Wang, Heming Huang
  • Publication number: 20250097586
    Abstract: A method of decoding an image, includes obtaining at least one offset for a picture, deriving a variable for scaling for the picture based on the at least one offset, and performing inter prediction based on the variable for scaling for the picture. The at least one offset is defined with a direction of scaling.
    Type: Application
    Filed: November 29, 2024
    Publication date: March 20, 2025
    Applicant: B1 INSTITUTE OF IMAGE TECHNOLOGY, INC.
    Inventor: Ki Baek KIM
  • Publication number: 20250098414
    Abstract: An all-oxide transistor structure includes a substrate having an upper surface and a first transistor disposed on the upper surface of the substrate. The first transistor includes a first drain, a first dielectric layer, a first source, at least one first opening and a first channel layer. The first drain, the first dielectric layer and the first source are disposed on the substrate along a first direction, and the first direction is parallel to a normal direction of the upper surface. The first opening passes through the first drain, the first dielectric layer and the first source along the first direction. The first channel layer, the first gate dielectric layer and the first gate are disposed in the first opening. The first gate dielectric layer is disposed on the first channel layer. The first gate is disposed on the first gate dielectric layer.
    Type: Application
    Filed: December 27, 2023
    Publication date: March 20, 2025
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Haw-Tyng HUANG, Po-Chun YEH, Hsien-Yi LIAO, Yao-Cing HAN
  • Publication number: 20250097587
    Abstract: A method of decoding an image, includes obtaining at least one offset for a picture, deriving a variable for scaling for the picture based on the at least one offset, and performing inter prediction based on the variable for scaling for the picture. The at least one offset is defined with a direction of scaling.
    Type: Application
    Filed: November 29, 2024
    Publication date: March 20, 2025
    Applicant: B1 INSTITUTE OF IMAGE TECHNOLOGY, INC.
    Inventor: Ki Baek KIM
  • Publication number: 20250092114
    Abstract: Methods for cancer immunotherapy are provided. The methods involve the use of a chimeric molecule (e.g., fusion protein) comprising an NKG2D portion and an Fc portion, which binds one or more NKG2D ligands. The methods disclosed herein are useful for the treatment of cancer that is associated with abnormal expression of one or more NKG2D ligands.
    Type: Application
    Filed: April 11, 2024
    Publication date: March 20, 2025
    Applicant: Dana-Farber Cancer Institute, Inc.
    Inventors: Glenn Dranoff, Matthew Vanneman, Gordon Freeman
  • Publication number: 20250093548
    Abstract: A sand shale formation lithology evaluation method and system for precise deep oil and gas navigation aims to solve the problem in the prior art, that is, the accuracy of the logging-while-drilling (LWD) azimuthal resistivity is insufficient due to an equipment or technology deficiency. The method includes: acquiring density distribution data, gamma distribution data, and resistivity distribution data of a target location; amplifying the data to acquire amplified logging distribution data; clustering the data to acquire clustered logging data; adding stratigraphic information to the clustered data; performing dimensionality reduction by a principal component analysis (PCA) method, and taking dimensionality-reduced data as a weight of azimuthal logging data to acquire an LWD feature dataset; predicting missing LWD photoelectric data through the LWD feature dataset; and acquiring a formation lithology evaluation result based on an LWD photoelectric data prediction curve.
    Type: Application
    Filed: September 9, 2024
    Publication date: March 20, 2025
    Applicant: INSTITUTE OF GEOLOGY AND GEOPHYSICS, CHINESE ACADEMY OF SCIENCES
    Inventors: Fei TIAN, Wenhao ZHENG, Qingyun DI, Yongyou YANG, Wenjing CAO
  • Publication number: 20250092161
    Abstract: The present disclosure belongs to a promotion system for cellular protein synthesis and use thereof, and specifically relates to the technical fields of cell metabolic engineering and synthetic biology. In the present disclosure, a RNA-binding protein (RBP) AbrP is provided. On one hand, the AbrP binds to translation-promoting factors FusA, LepA, and Era separately; on the other hand, the AbrP binds to a characteristic sequence of an sRNA. A complex resulting from the combination of the AbrP and the promoting factor reaches a translation system of a target mRNA under a guidance of the sRNA, thus releasing the translation-promoting factors FusA, LepA, and Era to stimulate and promote the translation. The present disclosure can solve the current urgent need and practical application for a regulatory element or regulatory system in a positive regulatory mode in the cell metabolic engineering or synthetic biology.
    Type: Application
    Filed: December 7, 2023
    Publication date: March 20, 2025
    Applicant: THIRD INSTITUTE OF OCEANOGRAPHY, MNR
    Inventors: Wanpeng WANG, Zongze SHAO, Zining WANG, Bin ZHI, Xiyan ZHANG