Patents Assigned to INSTITUTE
  • Patent number: 12258605
    Abstract: This invention relates to modified hydroxylases. The invention further relates to cells expressing such modified hydroxylases and methods of producing hydroxylated alkanes by contacting a suitable substrate with such cells.
    Type: Grant
    Filed: December 23, 2021
    Date of Patent: March 25, 2025
    Assignee: California Institute of Technology
    Inventors: Frances Arnold, Peter Meinhold, Matthew W. Peters, Rudi Fasan, Mike M. Y. Chen
  • Patent number: 12259344
    Abstract: Provided is a living cell microbeam directional and quantitative irradiation imaging apparatus. The problem that qualitative analysis of the mechanism of action of biological cells irradiated cannot accurately study the mechanism of action of different irradiation doses on biological cells as the cell irradiation technology can be only used to perform qualitative irradiation on living biological cells is solved. The apparatus includes a vertical microbeam terminal, a living cell directional irradiation module, a wide-field microscopic module, a mode switching module, and a single-proton counting and radiation synchronous control module.
    Type: Grant
    Filed: August 20, 2024
    Date of Patent: March 25, 2025
    Assignee: Harbin Institute of Technology
    Inventors: Chenguang Liu, Jian Liu, Zhao Chen
  • Patent number: 12258361
    Abstract: Provided are a directionally assembled flexible MOF hydrogel, a preparation method and a proton conduction application thereof. The prepared method includes: mixing a transition metal salt and L-Glu to prepare a mixed aqueous solution; putting the mixed aqueous solution into a reaction kettle to react at a constant reaction temperature in a range from 80° C. to 200° C. for a reaction period of 1-5 hours, to thereby obtain a reacted aqueous solution; cooling the reacted aqueous solution to room temperature; and washing the reacted aqueous solution after the cooling with deionized water and absolute ethanol, to thereby obtain the directionally assembled flexible MOF hydrogel, L-Glu-M (M?Zr, Fe, or Co), for sealing and storing. The preparation method is simpler and easier to operate, and the directionally assembled flexible MOF hydrogel has great prospects in the field of proton conducting technologies.
    Type: Grant
    Filed: May 3, 2024
    Date of Patent: March 25, 2025
    Assignees: Zhejiang University of Technology, Eco-Environmental Science Research & Design Institute of Zhejiang Province
    Inventors: Lei Qin, Xiaoyan Mao, Yingyu Tan, Fei Huang, Liang Zhang, Yu Zhang, Xingwei Xiang
  • Patent number: 12257565
    Abstract: [OBJECT] To provide an activated carbon for adsorbing per- and polyfluoroalkyl compounds in a water sample, the activated carbon having a high collection rate of per- and polyfluoroalkyl compounds in a water sample, and a filter body using the same. [ACHIEVING MEANS] An activated carbon for adsorbing per- and polyfluoroalkyl compounds in a water sample to desorbably adsorb per- and polyfluoroalkyl compounds in a water sample, wherein the activated carbon is composed of an activated carbon adsorbent having a BET specific surface area of 800 m2/g or more or a surface oxide amount of 0.20 meq/g or less, or alternatively, a BET specific surface area of 800 m2/g or more and a surface oxide amount of 0.50 meq/g or less, and wherein a sum (Vmic) of a volume of micropores of 1 nm or less of the activated carbon adsorbent is 0.30 cm3/g or more.
    Type: Grant
    Filed: August 11, 2020
    Date of Patent: March 25, 2025
    Assignees: FUTAMURA KAGAKU KABUSHIKI KAISHA, NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY
    Inventors: Nobuyoshi Yamashita, Sachi Taniyasu, Tsutomu Kousaka, Makoto Yokoi, Chiharu Hori, Kodai Shimamura, Takuya Asano
  • Patent number: 12259473
    Abstract: An optical measurement device and an optical measurement method that can accurately measure a distance and a velocity by removing an influence of a nonlinear chirp of a laser in FMCW LiDAR. The optical measurement device includes a laser that outputs light of which a frequency is modulated; a photodetector; a heterodyne optical system that splits output light of the laser into two components, uses one as probe light, uses the other as reference light, adds a frequency shift to one of the probe light and the reference light, applies the probe light to an object, combines scattered light from the object and the reference light, and causes the combined light to be incident on the photodetector; an IQ detector; and an arithmetic operation processor.
    Type: Grant
    Filed: November 15, 2019
    Date of Patent: March 25, 2025
    Assignee: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY
    Inventor: Hidemi Tsuchida
  • Patent number: 12259513
    Abstract: A sand shale formation lithology evaluation method and system for precise deep oil and gas navigation aims to solve the problem in the prior art, that is, the accuracy of the logging-while-drilling (LWD) azimuthal resistivity is insufficient due to an equipment or technology deficiency. The method includes: acquiring density distribution data, gamma distribution data, and resistivity distribution data of a target location; amplifying the data to acquire amplified logging distribution data; clustering the data to acquire clustered logging data; adding stratigraphic information to the clustered data; performing dimensionality reduction by a principal component analysis (PCA) method, and taking dimensionality-reduced data as a weight of azimuthal logging data to acquire an LWD feature dataset; predicting missing LWD photoelectric data through the LWD feature dataset; and acquiring a formation lithology evaluation result based on an LWD photoelectric data prediction curve.
    Type: Grant
    Filed: September 9, 2024
    Date of Patent: March 25, 2025
    Assignee: INSTITUTE OF GEOLOGY AND GEOPHYSICS, CHINESE ACADEMY OF SCIENCES
    Inventors: Fei Tian, Wenhao Zheng, Qingyun Di, Yongyou Yang, Wenjing Cao
  • Patent number: 12259421
    Abstract: The present application proposes an airborne electromagnetic signal observation device and a system carried by an unmanned aerial vehicle (UAV). The device includes an inner frame, an outer frame and a flexible support that are connected to each other. The device and the system can enhance the stability of the sensor in flight and greatly suppress motion noise.
    Type: Grant
    Filed: February 23, 2023
    Date of Patent: March 25, 2025
    Assignee: INSTITUTE OF GEOLOGY AND GEOPHYSICS, CHINESE ACADEMY OF SCIENCES
    Inventors: Xin Wu, Guoqiang Xue
  • Patent number: 12260162
    Abstract: A method and apparatus for printing an electric circuit directly on a target surface having a three-dimensional shape are provided. In this method, a 3D printing apparatus that can be attached to a target surface is used. In this printing method, two-dimensional information about the shape of the electric circuit to be printed and information about the three-dimensional shape of the target surface are input. Two-dimensional information about the shape of the electric circuit to be printed is adjusted based on the information about the three-dimensional shape of the target surface to generate three-dimensional information about the electric circuit to be printed. Based on this, a tool path for controlling the 3D printing apparatus is generated. An electric circuit can be directly fabricated on a target surface having a three-dimensional shape by the method and apparatus.
    Type: Grant
    Filed: January 17, 2022
    Date of Patent: March 25, 2025
    Assignee: KAIST (KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY)
    Inventors: Bianchi Andrea, Neung Ryu, Youngkyung Choi, Myung Jin Kim, Artem Dementyev
  • Patent number: 12258560
    Abstract: The present invention provides circularized RNA and methods of making and using same.
    Type: Grant
    Filed: April 8, 2021
    Date of Patent: March 25, 2025
    Assignee: DANA-FARBER CANCER INSTITUTE, INC.
    Inventors: Michael Goldberg, Ellese Carmona
  • Patent number: 12258651
    Abstract: A method for extracting germanium based on acid decomposition is provided, including acid decomposition and post-treatment steps, and specifically including: adding an acid to a coal ash for conditioning to obtain a material a; heating the material a to 350° C. to 800° C., and keeping the material a at this temperature for 10 min to 10 h to obtain an acid-decomposed material b; milling the acid-decomposed material b until more than 60% of a milled material has a particle size of less than 200 mesh to obtain a material c; subjecting the material c to distillation to obtain a residual slurry d and a distillation fraction e; and hydrolyzing the distillation fraction e with a dilute hydrochloric acid solution, and then oven-drying to obtain GeO2.
    Type: Grant
    Filed: September 27, 2024
    Date of Patent: March 25, 2025
    Assignee: KUNMING METALLURGICAL RESEARCH INSTITUTE CO., LTD.
    Inventors: Xiaocai He, Huixian Shi, Jiuyang Ren, Na Xu, Ye Yuan, Qingxin Xu, Yina Li, Qiugu He, Ting Ren, Yuan Xu, Weizhi Diao, Sen Yan, Hui Zhang
  • Patent number: 12260656
    Abstract: According to an embodiment of the present disclosure, there may be provided an operation method of a server for estimating the size of damage in disaster affected areas. In this instance, the operation method of the server may include acquiring at least one first disaster image, deriving an affected area from each of the at least one first disaster image, acquiring affected area related information through labeling based on the derived affected area, and training a first learning model using the at least one first disaster image and the affected area related information.
    Type: Grant
    Filed: May 4, 2022
    Date of Patent: March 25, 2025
    Assignee: NATIONAL DISASTER MANAGEMENT RESEARCH INSTITUTE
    Inventors: Seong Sam Kim, Dong Yoon Shin, Cheol Kyu Lee
  • Patent number: 12258378
    Abstract: This invention is directed to engineered cells and methods for using the same. In embodiments, the engineered cell comprises a nucleic acid encoding a chimeric antigen receptor and a polypeptide, wherein the chimeric antigen receptor is specific for two or more antigens on the surface of a cancer cell, and wherein the polypeptide comprises an antibody or fragment thereof that can be secreted from the engineered cell.
    Type: Grant
    Filed: March 14, 2019
    Date of Patent: March 25, 2025
    Assignee: Dana-Farber Cancer Institute, Inc.
    Inventors: Wayne A. Marasco, Quan Karen Zhu, Emily Kuiper
  • Patent number: 12260160
    Abstract: In an integrated circuit (IC) assessment method, an artificial intelligence (AI) component comprising at least one artificial neural network (ANN) is trained to transform layout rendering tiles of a rendering of a reference IC into corresponding reference layout image tiles extracted from at least one layout image of the reference IC. Using the trained AI component, standard cell layout renderings of a library of GDSII or OASIS standard cell layout renderings are transformed into as-fabricated standard cell layout renderings forming a library of as fabricated standard cell layout renderings. Instantiated standard cells and their placements in the layout image of an IC-under-test are identified by matching the instantiated standard cells with corresponding as-fabricated standard cell layout renderings retrieved from the library of as fabricated standard cell layout renderings.
    Type: Grant
    Filed: January 9, 2024
    Date of Patent: March 25, 2025
    Assignee: BATTELLE MEMORIAL INSTITUTE
    Inventors: Adam Kimura, Rohan Prabhu, Noah Mun
  • Patent number: 12259521
    Abstract: Provided are a method and system of analyzing ingredients of an artificial rainfall for verification of a cloud seeding effect. As the method and system, which can verify an effect of the artificial rainfall in such a manner that a seeding material becomes different according to each temperature of clouds at a seeding altitude, water sampling from precipitation is performed before and after seeding, and thus the ingredients of a water sample are analyzed using each of a method of analyzing a heavy metal component and a method of analyzing a water-soluble ion component according to a cool cloud and a warm cloud so that whether or not there is a change in each concentration of the ingredients can be determined, are provided, an experiment for the artificial rainfall can more effectively be performed.
    Type: Grant
    Filed: February 28, 2022
    Date of Patent: March 25, 2025
    Assignee: National Institute of Meteorological Sciences
    Inventors: Hae Jung Koo, Ki Ho Chang, Joo Wan Cha, Hyunjun Hwang, Minhoo Kim, Woon Seon Jung, Jung Mo Ku, Ji Man Park, Miloslav Belorid, Sang Hee Chae, Ha-Young Yang, Chulkyu Lee, Ji Min Woo, Eun Hye Sim, Chang Hee Kang, Jung Min Song
  • Patent number: 12258989
    Abstract: A connection lock for prefabricated components includes an auxiliary part and a main part which are each provided with a fixing structure for connecting with a prefabricated component in an anchoring fit manner. The auxiliary part includes an auxiliary part body, an auxiliary part transmission structure, and a lock pin structure which is movably mounted to the auxiliary part body. The auxiliary part transmission structure is in transmission fit with the lock pin structure. The main part includes a main part body, a main part transmission structure, and a locking structure. An inserting channel fitted with the lock pin structure is formed in the main part body. The locking structure is adjustably mounted in the main part body. The main part transmission structure is in transmission fit with the locking structure. It is rapid and convenient to operate, and the construction efficiency is higher than traditional construction methods.
    Type: Grant
    Filed: January 18, 2022
    Date of Patent: March 25, 2025
    Assignee: Guangzhou Metro Design & Research Institute Co., Ltd.
    Inventors: Xianli Ding, Zihui Zan, Xingzhong Nong, Juyang Wu, Haiou Shi, Bao Xiang, Ran Wang, Feiqi Ou, Qian Zhou, Hengyi Li, Chunjie Liu, Shengya He, Liang Ye
  • Patent number: 12259387
    Abstract: A system, method, apparatus and diagnostic test for Plasmodium vivax, to determine a likelihood of a specific timing of infection by P. vivax in a subject, and hence identify individuals with a high probability of being infected with otherwise undetectable liver-stage hypnozoites. The system, method, apparatus and diagnostic test relate to the identification of hypnozoites (“dormant” liver-stages), or at least of the likelihood of the subject being so infected. Optionally and preferably, the specific timing relates to recent infections, for example within the last 9 months.
    Type: Grant
    Filed: October 11, 2023
    Date of Patent: March 25, 2025
    Assignee: The Walter and Eliza Hall Institute of Medical Research
    Inventors: Ivo Mueller, Takafumi Tsuboi, Michael White, Rhea Longley
  • Patent number: 12259343
    Abstract: The present disclosure provides methods of collecting electron diffraction patterns from nanocrystals to obtain a three-dimensional structural model of a compound, as well as methods of identifying compounds and methods of determining polymorphic forms. In addition, the present disclosure provides methods of characterizing a first compound from a sample, as well as methods of screening compounds from a sample. The present disclosure also provides systems for characterizing a compound from a sample, which systems include modules for high-performance liquid chromatography, dispensing, and electron microscopy.
    Type: Grant
    Filed: September 10, 2020
    Date of Patent: March 25, 2025
    Assignees: The Regents of the University of California, California Institute of Technology
    Inventors: Hosea M. Nelson, Jose A. Rodriguez, Brian M. Stoltz, Tamir Gonen, Michael Martynowycz
  • Patent number: 12260865
    Abstract: Provided a method performed by an automatic interpretation server based on a zero user interface (UI), which communicates with a plurality of terminal devices having a microphone function, a speaker function, a communication function, and a wearable function. The method includes connecting terminal devices disposed within a designated automatic interpretation zone, receiving a voice signal of a first user from a first terminal device among the terminal devices within the automatic interpretation zone, matching a plurality of users placed within a speech-receivable distance of the first terminal device, and performing automatic interpretation on the voice signal and transmitting results of the automatic interpretation to a second terminal device of at least one second user corresponding to a result of the matching.
    Type: Grant
    Filed: July 19, 2022
    Date of Patent: March 25, 2025
    Assignee: Electronics and Telecommunications Research Institute
    Inventors: Seung Yun, Sang Hun Kim, Min Kyu Lee, Joon Gyu Maeng
  • Patent number: 12262122
    Abstract: A method of decoding an image, includes obtaining at least one offset for a picture, deriving a variable for scaling for the picture based on the at least one offset, and performing inter prediction based on the variable for scaling for the picture. The at least one offset is defined with a direction of scaling.
    Type: Grant
    Filed: November 6, 2023
    Date of Patent: March 25, 2025
    Assignee: B1 INSTITUTE OF IMAGE TECHNOLOGY, INC.
    Inventor: Ki Baek Kim
  • Patent number: 12262002
    Abstract: An image prediction method according to the present invention may comprise: identifying a reference pixel region designated for obtaining correlation information; determining a reference pixel processing configuration on the basis of determination of the availability of the reference pixel region; and performing intra prediction according to the determined reference pixel processing. As described above, performing intra prediction on the basis of the availability of a reference pixel according to the present invention can improve encoding performance.
    Type: Grant
    Filed: May 30, 2024
    Date of Patent: March 25, 2025
    Assignee: B1 INSTITUTE OF IMAGE TECHNOLOGY, INC.
    Inventor: Ki Baek Kim