Patents Assigned to INSTITUTE
  • Patent number: 12235613
    Abstract: Provided is a wireless time servicing method, device and system. The wireless time servicing method includes: obtaining absolute time information sent by an external clock source; correcting a system time of a master station according to the absolute time information; broadcasting path information to a slave station; receiving feedback from the slave station in response to the path information, calculating a transmission path delay between the master station and the slave station, and storing the transmission path delay in the time information; and sending the time information to the slave station.
    Type: Grant
    Filed: November 18, 2021
    Date of Patent: February 25, 2025
    Assignee: INSTITUTE OF GEOLOGY AND GEOPHYSICS, THE CHINESE ACADEMY OF SCIENCES
    Inventors: Xiqiang Xu, Tianyao Hao, Yaoxing Hu
  • Patent number: 12233060
    Abstract: The present invention relates to Ataxia-Telangiectasia Mutated and Rad3-related protein kinase (ATR) inhibitors for use in methods of treating BAF-complex deficient cancer. The present invention further provides methods for identifying ATR inhibitors for use in the treatment of BAF complex gene mutant or deficient cancers. Medical uses and methods relating to the treatment of synovial sarcoma using ATR inhibitors are also provided.
    Type: Grant
    Filed: January 6, 2017
    Date of Patent: February 25, 2025
    Assignees: THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL, BREAST CANCER NOW
    Inventors: Christopher James Lord, Chris Williamson, Samuel Jones
  • Patent number: 12235193
    Abstract: Embodiments of the present disclosure provide a physical test system of large-scale three-dimensional multi-functional landslide-prevention and control structure. The system comprises a model test tank, a bidirectional servo loading system, a multi-scale model transformation system, a sliding surface evolution visualization system, a positive pressure monitoring system, an artificial rainfall system, and a control system. The bidirectional servo loading system applies a horizontal load and a vertical load, and the multi-scale model transformation system includes a plurality of retractable counterforce brackets, configured to change a width of the model test tank; and the sliding surface evolution visualization system includes a plurality of filming devices, configured to record a whole evolution process of a landslide sliding surface evolution.
    Type: Grant
    Filed: September 4, 2024
    Date of Patent: February 25, 2025
    Assignees: RAILWAY ENGINEERING RESEARCH INSTITUTE, CHINA ACADEMY OF RAILWAY SCIENCES CO., LTD., CHINA ACADEMY OF RAILWAY SCIENCES CO., LTD.
    Inventors: Yufang Zhang, Jian Li, Kun Yuan, Zhenhua Yin, Zheyuan Xing, Wenjiao Zhou, Mengjia Liu, Zhongmin Yang, Guozhuang Song, Xu Gao, Jiawei Fan, Jian Cui, Bo Liu, Yunni Yang
  • Patent number: 12233830
    Abstract: A brake caliper diagnostic device for railway vehicles according to an embodiment of the present disclosure includes an internal pressure sensor located between a brake hose for delivering brake oil or compressed air to the brake caliper and an inlet of the brake caliper, internal temperature sensors respectively installed in the air breathers respectively located above and below the brake caliper, an assembly plate temperature sensor located adjacent to a brake pad assembly, a piston temperature sensor located on a surface of a brake caliper body adjacent to a piston, and a brake caliper monitoring device configured to determine whether or not the brake caliper is abnormal, based on data received from the internal pressure sensor, the internal temperature sensors, the assembly plate temperature sensor, and the piston temperature sensor.
    Type: Grant
    Filed: September 27, 2022
    Date of Patent: February 25, 2025
    Assignee: KOREA RAILROAD RESEARCH INSTITUTE
    Inventors: Yeon Su Kim, Sung Hyuk Park
  • Patent number: 12235498
    Abstract: A manufacturing method and application of an optical interconnection module are disclosed. According to example embodiments, by providing the method of manufacturing the optical interconnection module in which an optical fiber optical coupler is disposed at its lower portion by using the FOWLP process, it is possible to provide advantages such as lightness, thinness and compactness of the optical interconnection module, guarantee of signal integrity, and high yield in mass production. Further, it is possible to provide a structure providing an electrical ground to an electronic chip by mounting the electronic chip on ETB and capable of being used as a heat dissipation path.
    Type: Grant
    Filed: January 14, 2022
    Date of Patent: February 25, 2025
    Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Sae-Kyoung Kang, Joon Young Huh, Joon Ki Lee
  • Patent number: 12234161
    Abstract: A kitchen waste wastewater treatment equipment includes a reaction kettle, a discharging mechanism and a pressurizing mechanism. In the process of high-temperature and high-pressure thermal hydrolysis of wastewater in the present disclosure, the pressurizing disk in the pressurizing mechanism continuously moves downwards in a vacuum state in the reaction kettle, reducing the volume in the reaction kettle and thus increasing the pressure. The secondary pressurization of wastewater is achieved while using heating for high-temperature and high-pressure, and the high-temperature and high-pressure environment greatly improves the reaction rate of thermal hydrolysis. The thermal hydrolysis reaction also generates gas for further pressurization, which greatly improves the treatment efficiency of wastewater. Moreover, the pressurizing mechanism and the exhaust annular groove can separate the gas generated after thermal hydrolysis.
    Type: Grant
    Filed: September 4, 2024
    Date of Patent: February 25, 2025
    Assignee: Zhongcheng Institute (Beijing) Environmental Technology Co., Ltd.
    Inventors: Xiaoqing Hu, Tao Liu, Fengming Yue, Xingyu Zhang, Rufei Liu, Chao Ji, Feng Zhang, Liyu Liu, Zhongtao Sun, Miao Guo
  • Patent number: 12235230
    Abstract: This application relates to an optical sensor element. In one aspect, the optical sensor element includes a graphite column including one or more graphite rods. The optical sensor element may also include one or more first graphene layers partly or entirely covering each of both ends of the graphite column. The optical sensor element may further include one or more second graphene layers partly or entirely covering the outer circumferential surface of the graphite column. This application also relates to an optical sensor for measuring the concentration of a greenhouse gas and the optical sensor includes the optical sensor element.
    Type: Grant
    Filed: April 13, 2022
    Date of Patent: February 25, 2025
    Assignee: National Institute of Meteorological Sciences
    Inventors: Young Suk Oh, Su Ryon Shin, Hyun Young Jung, Sang Won Joo, Hae Young Lee, Chang Kee Lee, Yeon Hee Kim, Chu Yong Chung
  • Patent number: 12234361
    Abstract: The present disclosure relates to a combined treatment method for surface modification of fumed silica, which comprises the following steps: (1) two sets of modification devices are used to jointly treat fumed silica; the fumed silica is modified with a modifier in the reaction furnace of each set of modification devices to obtain two groups of modified fumed silica and exhaust gas respectively; (2) the exhaust gas obtained in step (1) is separated respectively to obtain unreacted modifier and by-products, and the obtained by-products are input into the reaction furnace of the other set of modification devices as reaction assistants to participate in the modification reaction; and the obtained unreacted modifiers are returned to the reaction furnace of the original modification device for repeated use.
    Type: Grant
    Filed: August 9, 2022
    Date of Patent: February 25, 2025
    Assignees: GUANGZHOU HUIFU RESEARCH INSTITUTE CO., LTD., HUBEI HUIFU NANOMATERIAL CO., LTD.
    Inventors: Xianjian Duan, Chunlei Wu, Yuelin Wang, Shiyu Xu, Chenggang Wang
  • Patent number: 12235231
    Abstract: The present invention discloses a laser heating single-sensor fast scanning calorimeter, which comprises an FSC sample chamber, a chip sensor positioned in the FSC sample chamber and used for loading a sample, a laser heater for heating the sample, an infrared camera for shooting a sample image, a communication terminal and a control electronic element, wherein a perspective window serving as a light path channel is arranged in a center of the FSC sample chamber, and the laser heater and the infrared camera are positioned at the top of the perspective window; the infrared camera is connected with the communication terminal; one end of the control electronic element is connected with the communication terminal, and the other end of the control electronic element is connected with the laser heater and the chip sensor.
    Type: Grant
    Filed: December 5, 2019
    Date of Patent: February 25, 2025
    Assignees: SHEYANG RESEARCH INSTITUTE OF NANJING UNIVERSITY, NANJING UNIVERSITY
    Inventors: Dongshan Zhou, Evgeny Zhuravlev, Jing Jiang, Qi Xue, Shaochuan Luo, Xiaoliang Wang, Wei Jiang, Qing Ji
  • Patent number: 12233994
    Abstract: Objects of the present invention are provide an evaluation method of ship propulsive performance in actual seas, an evaluation program of ship propulsive performance in actual seas and an evaluation system of ship propulsive performance in actual seas capable of precisely evaluating ship propulsive performance in actual seas on the same scale also before the ship sails for example. As solving means of the objects, a standard sailing model 2 of the ship in actual seas is set, a sailing condition of the ship and a ship condition of the ship are input to the standard sailing model 2, the standard sailing model 2 into which the sailing condition and the ship condition are input and the ship condition are applied to a previously verified calculating method 1 of ship performance in actual seas, and ship propulsive performance in actual seas is evaluated.
    Type: Grant
    Filed: March 28, 2024
    Date of Patent: February 25, 2025
    Assignee: NATIONAL INSTITUTE OF MARITIME, PORT AND AVIATION TECHNOLOGY
    Inventor: Masaru Tsujimoto
  • Patent number: 12235268
    Abstract: Compositions and methods for detection of anti-citrullinated protein antibodies (ACPAs) in rheumatoid arthritis (RA) patients. Patient samples known or suspected of containing ACPAs were probed against citrullinated proteins, and antibody responses to 190 citrullinated proteins in 20 RA patients were investigated. Unique antibody reactivity patterns in both clinical anti-cyclic citrullinated peptide assay positive (CCP+) and negative (CCP?) RA patients were observed. At individual antigen levels, six novel antibody/antigen complexes were discovered and validated against specific citrullinated antigens (Myelin Basic Protein (MBP), osteopontin (SPP1), flap endonuclease (FENI), insulin like growth factor binding protein 6 (IGFBP6), insulin like growth factor I (IGF1) and stanniocalcin-2 (STC2)) in RA patients. Identification of immune-dominant epitope(s) for citrullinated MBP was also performed. The identified biomarkers have high specificity, especially MBP.
    Type: Grant
    Filed: June 14, 2017
    Date of Patent: February 25, 2025
    Assignees: SCOTTSDALEARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY, BENAROYA RESEARCH INSTITUTE AT VIRGINIA MASON
    Inventors: Joshua LaBaer, Ji Qiu, Kailash Karthikeyan, Jane Buckner, Gerald Nepom
  • Patent number: 12234005
    Abstract: Provided is a system for controlling an RPM of a propeller and a rotor of a flight vehicle having multiple power units including: a collective pitch angle command generating unit generating a collective pitch angle command upon receiving a thrust control command from a pilot or an automatic controller; a disturbance factor compensating unit for generating an RPM compensation electronic speed control (ESC) command for compensating for an RPM error, and an electronic speed adjustment command generating unit generating a final ESC command upon receiving a collective command input or derived in the process of generating the collective pitch angle command by the collective pitch angle command generating unit and the RPM compensation ESC command generated by the disturbance factor compensating unit. RPMs of motors of a flight vehicle having a plurality of propellers and rotors may be maintained to be the same.
    Type: Grant
    Filed: November 26, 2020
    Date of Patent: February 25, 2025
    Assignee: KOREA AEROSPACE RESEARCH INSTITUTE
    Inventors: Youngshin Kang, Am Cho, Bumjin Park, Seongwook Choi, Sam Ok Koo, Chang Sun Yoo, Yushin Kim
  • Patent number: 12235327
    Abstract: A method for calculating state of health of battery, performed by a processing control circuit, includes: charging a battery under test to an upper voltage with a first constant current through a charging circuit and an electrical measuring circuit, discharging the battery under test to a lower voltage with a second constant current through the charging circuit and the electrical measuring circuit, obtaining an accumulated discharge capacity from the upper voltage to the lower voltage through the electrical measuring circuit, and calculating a state of health of the battery under test at least according to the accumulated discharge capacity and a design capacity.
    Type: Grant
    Filed: January 26, 2023
    Date of Patent: February 25, 2025
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Yu-Hong Shen, Po-Wei Chen, Tsan-Huang Chen
  • Patent number: 12234543
    Abstract: A method for preparing bismuth oxide nanowire films by heating in an upside down position includes: washing a substrate, and fixing the substrate to a substrate support in a magnetron sputtering system in a position where an electrically conductive surface of the substrate faces downwards; placing a bismuth target, which is adhered to a copper backing plate, on a sputtering head in the magnetron sputtering system; performing direct current magnetron sputtering to form a bismuth film on the electrically conductive surface of the substrate; and regulating a heating temperature to maintain the bismuth film in a semi-molten state, and providing a predetermined oxygen gas concentration to form the bismuth oxide nanowire film.
    Type: Grant
    Filed: August 18, 2020
    Date of Patent: February 25, 2025
    Assignee: Institute of Analysis. Guangdong Academy of Sciences (China National Analytical Center, Guangzhou)
    Inventors: Fuxian Wang, Liling Wei, Qiong Liu, Hui Cheng
  • Patent number: 12237213
    Abstract: A method for manufacturing a semiconductor device. A photolithographic coating, including a first film, a photolithographic film, and a second film, is formed on the to-be-connected structure. Refractive indexes of the first film and the second film are smaller than 1. The photolithographic coating is exposed to a light having a first wavelength, to image the to-be-connected structure to a first region of the photolithographic film. The photolithographic coating is exposed to a light having a second wavelength through a mask, to image the mask to a second region of the photolithographic film. A region in which the first region and the second region overlap serves as a connection region corresponding to the to-be-connected structure, and thereby self-alignment between a layer of the to-be-connected structure and a layer where a contact hole is arranged is implemented.
    Type: Grant
    Filed: November 12, 2021
    Date of Patent: February 25, 2025
    Assignee: Institute of Microelectronics, Chinese Academy of Sciences
    Inventors: Libin Zhang, Yayi Wei, Zhen Song
  • Patent number: 12234576
    Abstract: The present disclosure provides a photochromic thermal insulation fiber including a core layer and a sheath layer covering the core layer. The core layer includes about 99 parts by weight to 100 parts by weight of polypropylene and about 0.4 parts by weight to 0.6 parts by weight of a photochromic dye. The sheath layer includes about 98 parts by weight to 99 parts by weight of nylon and about 1 part by weight to 2 parts by weight of a near-infrared reflecting dye.
    Type: Grant
    Filed: March 17, 2022
    Date of Patent: February 25, 2025
    Assignee: TAIWAN TEXTILE RESEARCH INSTITUTE
    Inventors: Jo-Cheng Chiang, Chao-Huei Liu
  • Patent number: 12236573
    Abstract: Systems for determining an end-point of a delayering process using optical end-point detection are described. In embodiments, the systems include a controller with an optical end-pointing (OE) module that is configured to determine an end-point of a delayering process based at least in part on the color or thickness of a surface layer of an integrated circuit (IC). In embodiments, the OE module determines whether an end-point of the delayering process has been reached based at least in part on a comparison of a determined thickness of an IC surface layer to a target thickness. The thickness of the surface layer may be determined by the OE module using a machine learning model, such as a convolutional neural network. Methods of identifying an end-point of a delayering process are also described.
    Type: Grant
    Filed: December 1, 2021
    Date of Patent: February 25, 2025
    Assignee: Battelle Memorial Institute
    Inventors: Jonathan Scholl, Nicholas Darby, Joshua Baur
  • Patent number: 12234454
    Abstract: The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non-naturally occurring or engineered DNA or RNA-targeting systems comprising a novel DNA or RNA-targeting CRISPR effector protein and at least one targeting nucleic acid component like a guide RNA.
    Type: Grant
    Filed: October 21, 2016
    Date of Patent: February 25, 2025
    Assignees: THE BROAD INSTITUTE, INC., MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Aaron Andrew Smargon, Feng Zhang
  • Patent number: 12236457
    Abstract: A multidimensional knowledge transfer model for predicting CTR of a computational ad, the multidimensional knowledge transfer model comprises: a pre-processor for building an ad group node graph based on similarities among ad group nodes, an ad campaign node graph from merging the ad group node graph, and an ad account node graph from merging the ad campaign node graph. The multidimensional knowledge transfer model further comprises a multi-knowledge CTR prediction model for each of the ad account, ad campaign, and ad group layers. The multi-knowledge CTR prediction model predicts the respective node's CTR from the ad account node graph, ad campaign node graph, or ad group node graph, features of the audience group, and features of the node having its CTR predicted appended with the hidden vector of its parent node extracted from the upper layer multi-knowledge CTR prediction model.
    Type: Grant
    Filed: August 3, 2022
    Date of Patent: February 25, 2025
    Assignee: Hong Kong Applied Science and Technology Research Institute Company Limited
    Inventors: Qijun Zhu, Xin Zheng, Ming Ming Tan
  • Patent number: 12234482
    Abstract: Provided are a culture medium for expanding and cultivating human liver progenitor cells and an application thereof. The chemical components of the formula of the described culture medium are clear, no serum is present, and various components thereof cooperate with each other to synergize. The culture medium is used for the long-term expansion and cultivation of liver progenitor cells in vitro and is used for maintaining the dryness thereof, is beneficial in quickly and efficiently obtaining a large number of functional liver cells, and is suitable for clinical hepatocyte transplantation application as well as for the use of hepatocyte reactors in bioartificial livers.
    Type: Grant
    Filed: December 19, 2019
    Date of Patent: February 25, 2025
    Assignee: GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES
    Inventors: Yinxiong Li, Tingcai Pan, Yan Chen, Yuanqi Zhuang, Fan Yang