Abstract: A dispersion of formononetin solid lipid nanoparticles and process for its preparation, namely having (i) a core system comprising formononetin, a lipid base, and a fluid medium, and (ii) an emulsifier system comprising an emulsifier, and water. The dispersion of formononetin solid lipid nanoparticles of the present disclosure can be used for treating cancer, osteoporosis, diabetes, and inflammation. The dispersion of formononetin solid lipid nanoparticles of the present disclosure are biocompatible, biodegradable, has improved solubility, has enhanced controlled drug release profile and are stable.

Abstract: In a biomimetic artificial muscle module, a biomimetic artificial muscle assembly having the biomimetic artificial muscle module, and a method of controlling the biomimetic artificial muscle module, the biomimetic artificial muscle module includes an operating part, an elastic part, a driving part, a locking part and first and second sensors. The operating part contracts or relaxes along a longitudinal direction. The elastic part is connected to a first end of the operating part, and behaves elastically behave according to an external force. The driving part is connected to a second end of the operating part, and drives the operating part to be contracted or relaxed. The locking part selectively blocks a length of the operating part from being changed. The first and second sensors respectively sense the elastic part and the operating part.

Abstract: The present invention discloses an acoustic sensor for rock crack detection including an acoustic emission probe, a probe installation mechanism and a transmission mechanism which transmits a combination of the probe installation mechanism and the acoustic emission probe to a setting position inside a borehole in the monitored rock mass. The acoustic emission probe installation mechanism essentially includes a sleeve component, a guide component, an end cap and springs. The guide component is in pluggable connection with the sleeve component or the end cap. The assembled probe installation mechanism locks the acoustic emission probe in a probe sleeve of the sleeve component. The springs inside the elastic sleeve of the sleeve component are in a compressed state.

Abstract: An all-quadrant measurement method for a middle-large magnetic field includes the steps of placing four orthogonally configured magnetic resistances in an external magnetic field; determining two magnetic resistances with the minimum resistance values, thereby determining that the other two magnetic resistances are in an S1 status, and making resistance values of the two magnetic resistances which are in the S1 status be R1 and R2, and at the same time taking an initial reference layer magnetization direction of the two magnetic resistances as a given reference layer magnetization direction when there is no magnetic field; respectively calculating an included angle between a free layer magnetization direction and the reference layer magnetization direction of the two magnetic resistances; respectively calculating the free layer magnetization direction of the two magnetic resistances; and solving a magnetic field amplitude and direction of the external magnetic field.

Abstract: An optical interferometer includes a beam splitter module and an optical sensor. The beam splitter module includes a lens assembly and a splitter cube. A light incident surface of the splitter cube is substantially orthogonal to an optical axis of the lens assembly. An acute angle is between the light incident surface and a light splitting surface of the splitter cube. A sampling surface of the splitter cube is substantially parallel to the light incident surface. A light reflecting surface of the splitter cube is substantially orthogonal to the light incident surface. The light incident surface is closer to the lens assembly than the sampling surface. A reference arm is defined between a splitter position on the light splitting surface and the light reflecting surface, a sample arm is defined between the splitter position and the sampling surface, and the reference arm is longer than the sample arm.

Abstract: Disclosed are a pincer-type ligand having a structurally rigid acridane structure and a metal complex consisting of the pincer-type ligand and a metal bound to each other, and exhibiting high reactivity and stability during a variety of bonding activation reactions. T-shaped complexes can be prepared from acriPNP(4,5-bis(diisopropylphosphino)-2,7,9,9-tetramethyl-9H-acrid in-10-ide), which is a pincer-type PNP ligand having an acridane structure, and metal complexes, which can be structurally rigid and thus exhibit excellent reactivity and stability based on minimized structural change thereof, can be prepared by introducing an acridane structure into the backbone thereof. The PNP ligand is structurally stable and has novel chemical properties, as compared to conventional similar ligands, and thus can be utilized in a wide range of catalytic reactions and material chemistry.

Abstract: The present disclosure relates to an IrO2 electrodeposited porous titanium composite layer of a polymer electrolyte membrane water electrolysis apparatus serving as both a diffusion layer and an oxygen electrode, the apparatus including: a porous titanium (Ti) layer; and an electrodeposited iridium oxide (IrO2) layer on the porous Ti layer. The IrO2 layer may be uniformly deposited on a porous Ti layer through an electrolysis process, and the electrodeposited IrO2 layer may play multiple roles as not only a catalyst layer toward oxygen evolution reaction (OER) on the surface of the Ti layer, but also a corrosion-protection layer which prevents an inner Ti layer from corrosion.

Abstract: A computer-implemented method of building a database of pulse sequences for parallel-transmission magnetic resonance imaging, includes a) for each of a plurality of subjects, determining an optimal sequence for the subject; b) for each subject, computing the values of the or of a different cost or merit function obtained by playing the optimal sequences for all the subjects; c) aggregating the subjects into a plurality of clusters using a clustering algorithm taking the values, or functions thereof, as metrics; d) for each cluster, determining an averaged optimal sequence for the cluster; e) receiving, as input, a set of features characterizing an imaging subject, comprising at least a morphological feature of the subject; f) associating the subject to one pulse sequence of the database based on the set of features using the computer-implemented classifier algorithm; and g) performing magnetic resonance imaging using the pulse sequence.

Abstract: The memory device includes multiple stacked layers of memory cells. Each of the layers includes a first array of first memory cells and a second array of second memory cells, which are nested with each other. The first memory cells and the second memory cells in the respective layers are substantially aligned to each other in a stacking direction of the memory cell layers. Each of the first memory cells is a vertical device based on a first source/drain layer, a channel layer, and a second source/drain layer stacked. Each of the second memory cells is a vertical device based on an active semiconductor layer extending in the stacking direction. The first and second memory cells include respective storage gate stacks, which share a common gate conductor layer. Gate conductor layers in the same memory cell layer are integral with each other.

Abstract: The present invention relates to a method for producing a 3- to 3.5-valent vanadium solution from a 4-valent vanadium solution by a catalytic reaction in the presence of a reducing agent, which generates a gas product during oxidation; a method for producing an electrolyte for a vanadium redox flow battery; and an apparatus for producing a liquid electrolyte for a vanadium redox flow battery. The present invention is characterized in that when a 3- to 3.5-valent vanadium electrolyte is produced from a 4-valent vanadium electrolyte by a catalytic reaction in the presence of a reducing agent, which generates a gas product during oxidation, the gas product produced in the catalytic reaction is captured with inert gas bubbles, which are carrier gases, and is removed from the reaction solution of the catalytic reaction by gas-liquid phase separation, thereby accelerating the catalytic reaction towards the forward reaction.

Abstract: A genetically modified microorganism includes: an exogenous nucleic acid sequence encoding naphthalene dioxygenase (NDO), wherein the endogenous icd gene of the genetically modified microorganism is knocked out, in which the endogenous icd gene encodes isocitrate dehydrogenase (IDH), and wherein the genetically modified microorganism is capable of using glutamic acid and/or a salt thereof as a nitrogen source to grow and producing indigo dye.

Abstract: Synthetically-derived and previously inaccessible modifications of 20?-hydroxy-vinca derivative compounds such as vinblastine, vincristine or vindesine are disclosed that are a stunning 100-fold more active than the natural product (IC50's 50-75 pM vs 7 nM, HCT116), and are now accessible as a result of advances in the total synthesis of the natural product. Illustrative new ultra-potent vinblastines bind tubulin with much higher affinity and likely further disrupt the tubulin head-to-tail ?/? dimer-dimer interaction by virtue of the strategic placement of an added conformationally well-defined, rigid and extended C20?-urea along the adjacent protein-protein interface. Added molecular complexity was used to markedly enhance target binding and functional biological activity, and represents a general approach to improving the properties of other natural products targeting a protein-protein interaction.

Abstract: A method for avoiding transmission of side information by a Partial Transmit Sequence, comprising the following steps: Step 1: determining an indication sequence of a data sub-carrier and a pilot sub-carrier; Step 2: grouping the frequency domain data blocks including data and pilots to reduce the peak-to-average power ratio (PAPR) of the OFDM signal by phase rotation according to the PTS method. Step 3: processing the pilot of the received signal through channel estimation based on fast Fourier transform interpolation to obtain a frequency domain channel response, and extracting a phase rotation sequence. Step 4: equalizing the received data through the obtained frequency domain channel response. Step 5: performing inverse rotation of phase on the equalized data through the phase rotation information extracted in Step 3 to obtain transmitted data symbols.

Abstract: The present application provides stable peptide-based Akt capture agents and methods of use as detection and diagnosis agents and in the treatment of diseases and disorders. The application further provides methods of manufacturing Akt capture agents using iterative on-bead in situ click chemistry.

Abstract: The invention is directed to isolated Tilapia Lake Virus or TiLV, and isolated nucleic acids sequences and polypeptides thereof. The invention also relates to probes and primers, and to antibodies against antigens from TiLV, and use of these reagents for detecting the presence or absence of TiLV in an animal. The invention also relates to iRNAs which target nucleic acid sequences of TiLV. The invention is also related to immunogenic compositions, including antibodies and vaccines, for inducing an immune response against TiLV in an animal. The invention is also related to gene constructs and cells comprising TiLV and isolated nucleic acids sequences and polypeptides thereof for use in developing prophylactic and therapeutic agents.

Abstract: A method of forming a core-shell composite material includes depositing a polysiloxane shell to wrap a ceramic core via chemical vapor deposition for forming a core-shell composite material, wherein the ceramic core is an oxide of metal and silicon, which includes 100 parts by weight of calcium, 50 to 95 parts by weight of iron, 15 to 40 parts by weight of silicon, 2 to 15 parts by weight of magnesium, 2 to 20 parts by weight of aluminum, and 2 to 10 parts by weight of manganese.

Abstract: The present subject matter describes system (100) for magnetic enrichment of magnetically marked analytes. The system has capture chip (102) comprising a sample chamber (104) for holding sample having magnetically marked analytes, and a recovery chamber (106) connected to the sample chamber by a channel (202). The volume of recovery chamber is smaller than volume of sample chamber (104). The system has magnetic arrangement (108) comprising a set of magnets (110) in which each two adjacent magnets have opposite polarities facing sample chamber. Set of magnets has dimensions that at least conform to coverage area of sample chamber. The magnetic arrangement also has at least one recovery magnet (112) having dimensions conforming to coverage area of recovery chamber and on alignment, the at least one recovery magnet (112) is at a distance farthest away from the recovery chamber. The system has a linear positioner (114) for moving the magnetic arrangement.

Abstract: The present disclosure relates to a Clostridium sp. JS66 strain producing metabolites having 4 to 6 carbon atoms in a high yield. The strain produces metabolites having 6 carbon atoms in a significantly high yield while reducing the production of acetic acid and ethanol as by-products.

Abstract: The invention relates to a molecular sieve SCM-15, a preparation process and use thereof. The molecular sieve comprises a schematic chemical composition of a formula of “SiO2.GeO2”, wherein the molar ratio of silicon and germanium satisfies SiO2/GeO2?1. The molecular sieve has unique XRD diffraction data and can be used as an adsorbent or a catalyst.

Abstract: A nanowire semiconductor device having a high-quality epitaxial layer. The semiconductor device may include: a substrate; one or more nanowires spaced apart from the substrate, wherein the nanowires each extend along a curved longitudinal extending direction; and one or more semiconductor layers formed around peripheries of the respective nanowires to at least partially surround the respective nanowires, wherein the respective semiconductor layers around the respective nanowires are spaced apart from each other.