Abstract: A speech extraction method based on the supervised learning auditory attention includes: converting an original overlapping speech signal into a two-dimensional time-frequency signal representation by a short-time Fourier transform to obtain a first overlapping speech signal; performing a first sparsification on the first overlapping speech signal, mapping intensity information of a time-frequency unit of the first overlapping speech signal to preset D intensity levels, and performing a second sparsification on the first overlapping speech signal based on information of the preset D intensity levels to obtain a second overlapping speech signal; converting the second overlapping speech signal into a pulse signal by a time coding method; extracting a target pulse from the pulse signal by a trained target pulse extraction network; converting the target pulse into a time-frequency representation of the target speech to obtain the target speech by an inverse short-time Fourier transform.

Abstract: A high voltage logic circuit for high voltage system application comprises a first device layer formed from a first semiconductor material and comprises a low voltage logic circuit; and a second device layer formed from a second different semiconductor material and comprising one or more components of an additional circuit for generating a high voltage logic output from a low voltage logic input from the low voltage logic circuit; wherein the first and second device layers are integrally formed.

Abstract: Disclosed are a composition for clearing spheroids, a method for clearing spheroids using same, and a kit comprising same. The composition for clearing spheroids can clear the spheroids in a convenient and rapid manner and thus may be usefully used for imaging of spheroids and in identifying the causes of various diseases, treating the diseases, and predicting the therapeutic effects and toxicity of drugs. In addition, the composition may be used in combination with various medical devices, and in particular, can be prepared as a kit and usefully used as an in vitro medical diagnostic device.

Abstract: A three-dimensional object detection method includes: extracting a target in a two-dimensional image by a pre-trained deep convolutional neural network to obtain a plurality of target objects; determining a point cloud frustum in a corresponding three-dimensional point cloud space based on each target object; segmenting the point cloud in the frustum based on a point cloud segmentation network to obtain a point cloud of interest; and estimating parameters of a 3D box in the point cloud of interest based on a network with the weighted channel features to obtain the parameters of the 3D box for three-dimensional object detection. According to the present invention, the features of the image can be learned more accurately by the deep convolutional neural network and the parameters of the 3D box in the point cloud of interest are estimated based on the network with the weighted channel features.

Abstract: A fracturing method, to cause a crack in bedrock, includes installing a depressurizing device in a well in the bedrock, and depressurizing the inside of the well with the installed depressurizing device. The installing step includes installing, in the well, a connecting pipe, which is connected to the depressurizing device, and a packer, which is attached to the connecting pipe, and the depressurizing step includes shutting off a gap between the well and the connecting pipe, with the packer, and depressurizing a region in the well below the packer, with the depressurizing device.

Abstract: The present invention relates to compounds, compositions and methods for treating diseases or conditions mediated by proteins of the SWI/SNF chromatin-remodeling complex, including PB1.

Abstract: Disclosed are a communication system and an operating method thereof. A plurality of electronic devices for forming a group may be configured to share a homomorphic encryption (HE) key. A server may be configured to generate a Boolean circuit for performing an operation based on input values corresponding to the number of electronic devices. Each of the electronic devices may be configured to transmit an encrypted session ephmeral key to the server through HE. The server may be configured to calculate an HE-evaluated value by applying the encrypted session ephmeral keys as the input values of the Boolean circuit. The server may be configured to transmit the HE-evaluated value and a given random number to each electronic device. Each electronic device may be configured to generate a common session key for the group based on the HE key, the HE-evaluated value and the given random number through homomorphic decryption.

Abstract: An electronic heating/cooling garment includes: a neck part, a collar (neckband), or an underarm part where a Peltier device (31) is placed; and a front body or a back body where a heating medium circulation path (35) and a battery (35) are placed, the battery (35) being configured to supply electric power to a pump (341) and the Peltier device (31). The heating medium circulation path (35) is composed of a flexible thermally conductive material having a tubular shape and holds a heating medium therein in an airtight manner. The heating medium circulation path has a first electrode and a second electrode on its outer surface. The first and second electrodes are configured to supply the electric power from the battery (35) to the Peltier device (31) and the pump (341).

Abstract: The present invention provides methods for retaining and expressing physiologically active substances in a target tissue-specific-manner, by administering the physiologically active substances to target submucous tissue. Specifically, the present inventors demonstrated that, when physiologically active substances were directly administered into submucous tissues without using a carrier, the physiologically active substances were effectively and safely retained at the administration sites over long periods without loss and diffusion, and produced the effect acting in a reservoir-like fashion. The physiologically active substances administered as described above were demonstrated to produce the therapeutic effect without having an influence on organs other than the administered organ.

Abstract: The present invention relates to a culture vessel for three-dimensional cell cultivation and a three-dimensional cell co-cultivation method using the same. The culture vessel comprises a well formed by a column positioned thereon and at least one support protruding from the column within the well. In contrast to conventional techniques, the present invention allows cells to be cultured at a position spaced from a culture vessel, thus enjoying the advantage of smoothly supplying oxygen necessary for three-dimensional cell culture structures.

Abstract: Provided are a coherent optical receiver and a fabrication method thereof, the coherent optical receiver including a substrate, signal and local input waveguides extending in a first direction parallel to a top surface of the substrate and configured to receive an optical signal, a first optical circuit element including a first optical waveguide connected to the signal input waveguide and a trench provided in one side of the first optical waveguide in parallel to the first direction, a second optical circuit element including a second optical waveguide connected to the first optical waveguide, a slit crossing the second optical waveguide, and a wavelength plate inserted to the slit, and third optical circuit elements connected to the second optical circuit element, wherein the first to third optical circuit elements are monolithically integrated in the substrate.

Abstract: Disclosed is a carbon dioxide absorbent and a carbon dioxide separation method using the same that greatly reduces energy consumption due to a small amount of latent heat required in regeneration of absorbents, enhances CO2 absorption rate, undergoes almost no thermal denaturation even at high temperatures while absorbing carbon dioxide, and results in a considerable reduction of the cost associated with absorption of carbon dioxide.

Abstract: Provided are a user interface device and a control method thereof for supporting easy and accurate selection of overlapped objects. The user interface device is a device for providing a user interface applied to a three-dimensional (3D) virtual space in which a plurality of virtual objects is created, and includes a gaze sensor unit to sense a user's gaze, an interaction sensor unit to sense the user's body motion for interaction with the virtual object in the 3D virtual space, a display unit to display the 3D virtual space, and a control unit to, when the user's gaze overlaps at least two virtual objects, generate projection objects corresponding to the overlapped virtual objects, wherein when an interaction between the projection object and the user is sensed, the control unit processes the interaction as an interaction between the virtual object corresponding to the projection object and the user.

Abstract: The present disclosure relates to ocular mucoadhesive pharmaceutical compositions comprising fluoroquinolone antibiotic, chitosan, polyvinyl alcohol and polyvinylpyrrolidone, their uses and methods of using such compositions.

Abstract: Disclosed are a method and an apparatus for providing low-latency services in a communication system. A downlink communication method may comprise receiving downlink control information (DCI) including resource allocation information from a base station through a control channel of a subframe #n; receiving downlink data from the base station through a data channel of a subframe #n+k indicated by the resource allocation information included in the DCI; and transmitting a first hybrid automatic repeat request (HARQ) response for the downlink data to the base station through a control channel of a subframe #n+k+l. Thus, the performance of the communication system can be improved.

Abstract: The present application provides bifunctional compounds of Formula (Ia) or (Ib): or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, stereoisomer, or tautomer thereof, which act as protein degradation inducing moieties for cyclin-dependent kinase 8 (CDK8). The present application also relates to methods for the targeted degradation of CDK8 through the use of the bifunctional compounds that link a ubiquitin ligase-binding moiety to a ligand that is capable of binding to CDK8 which can be utilized in the treatment of disorders modulated by CDK8.

Abstract: The present invention relates to a method of enhancing heat transfer of metallic surfaces by (1) fabricating hierarchical micro-nanostructured surfaces using etching processes, and (2) fabricating hydrophobic and hydrophilic regions, using a printing or a coating technique, followed by etching. The said method enhances the density of condensation sites over a metallic surface and additionally facilitates the departure of condensed droplets from the surface. Such a surface also enhances the sensible heat transfer characteristics, and improves the coefficient of performance (COP) of refrigeration systems for applications like atmospheric water generators, dehumidifiers, air conditioners, etc.

Abstract: A detector based on a gallium nitride-based enhancement-mode device and a manufacturing method thereof. The detector is a gas or solution detector. When the detector is used in electrolyte solution detection, electrolyte solution is located in the gate opening region and directly contacts the thin barrier layer to form a contact interface. The electrolyte solution affects interface charges at the contact interface, leading to a change in a concentration of the two-dimensional electron gas, and further a change in a current between the source and the drain. When the detector is used in a hydrogen-containing gas detection, the H concentration of the hydrogen-containing gas affects interface charges at the contact interface between the gate and the thin barrier layer, leading to a change in a concentration of the two-dimensional electron gas, and further a change in the current between the source and the drain.

Abstract: A method of detecting the likelihood of a seizure event in a patient includes at successive expirations of a first time interval, determining a first likelihood that the patient is experiencing a seizure based on electrodermal activity and a movement of a limb of the patient. The method also includes at successive expirations of a second time interval, determining whether the patient experienced a seizure in a second time period preceding the determining based on a heart rate of the patient. In response to determining that the third comparison result satisfies at least a third detection criterion, the method compares electrodermal activity and the movement of a limb of the patient to determine a second likelihood. In response to determining that the second likelihood satisfies a second detection criterion, the method triggers presentation of a second alert regarding a potential seizure.

Abstract: The present invention provides a composition that controls pharmacokinetics. Specifically, the present invention provides: a composition for controlling pharmacokinetics, the composition containing a polyvalent cation as an active ingredient; and a method for controlling pharmacokinetics using the polyvalent cation.