Abstract: Design and development of an affordable, user-friendly, and portable POCT hand tremor detection device has been reported. This device is composed of a detection unit, a flexible pressure sensor, a signal processing unit, and a power supply. The detection unit is composed of the sensor and press-knob. The flexible pressure sensor is a combination of usually spaced apart flexible polymer preferably polydimethylsiloxane, flexible substrate preferably paper, and a conductive coating preferably reduced graphene oxide (RGO). When the users put pressure on the press-knob through the fingers, the flexible pressure sensor actuates and bends so that conductive RGO layers on the flexible substrates come in contact with each other to generate an output current.

Abstract: An apparatus and method for abnormal situation detection are disclosed. An abnormal situation detection apparatus can map first sensor data among sensor data transmitted from a plurality of sensors into a vector value, convert it into first situation information in the form of an image pattern, and generate a learning model using the first situation information and an abnormal situation reference range. In addition, the abnormal situation detection apparatus can convert second sensor data among sensor data transmitted from a plurality of sensors into a form that can be input to the learning model, and determine whether an abnormal situation occurs by applying the converted second data to the learning model.

Abstract: Provided herein is a composition comprising a deliverable substance in a matrix for controlled delivery. The composition comprises cellulose micro fibers (“CMF”), an inert particle substance, and a deliverable substance. This general formula may be applied to a wide range of products, as discussed in detail below. For example, described herein are dog treat compositions comprising cellulose micro fibers which are a substitute for rawhide dog chews. Dog treats made as described herein are very durable and have a wide spectrum of possible sizes, flavors and properties.

Abstract: A shear box for testing cyclic shear characteristics of a rock mass discontinuity includes: an upper shear box including an upper semi-open cavity composed of an upper left side plate, an upper right side plate, an upper front side plate, an upper rear side plate and an upper top plate; and a lower shear box including a lower semi-open cavity composed of a lower left side plate, a lower right side plate, a lower front side plate, a lower rear side plate and a lower bottom plate; the upper shear box includes at least one first adjusting device for adjusting a space size of the upper semi-open cavity; the lower shear box includes at least one second adjusting device for adjusting a space size of the lower semi-open cavity; and the upper shear box and the lower shear box are placed opposite to each other.

Abstract: A computing in-memory system and computing in-memory method based on a skyrmion race memory are provided. The system comprises a circuit architecture of SRM-CIM. The circuit architecture of the SRM-CIM comprises a row decoder, a column decoder, a voltage-driven, a storage array, a modified sensor circuit, a counter Bit-counter and a mode controller. The voltage-driven includes two NMOSs, and the two NMOSs are respectively connected with a selector MUX. The modified sensor circuit compares the resistance between a first node to a second node and a third node to a fourth node by using a pre-charge sense amplifier. The storage array is composed of the skyrmion racetrack memories. The computing in-memory architecture is designed by utilizing the skyrmion racetrack memory, so that storage is realized in the memory, and computing operation can be carried out in the memory.

Abstract: Provided is a compound that thickens a fluid organic material to a desired viscosity and uniformly stabilizes composition thereof. A compound of the present invention is represented by Formula (1): where R1 represents a monovalent linear aliphatic hydrocarbon group having from 10 to 25 carbons; R2 and R3 are the same or different, representing a divalent aliphatic hydrocarbon group having 2, 4, 6, or 8 carbons, a divalent alicyclic hydrocarbon group having 6 carbons, or a divalent aromatic hydrocarbon group; R4 represents a divalent aliphatic hydrocarbon group having from 1 to 8 carbon(s); R5 and R6 are the same or different, representing a monovalent aliphatic hydrocarbon group having from 1 to 3 carbon(s) or a hydroxyalkylether group L1 to L3 represent an amide bond; in a case where L1 and L3 are —CONH—, L2 is —NHCO—, and in a case where L1 and L3 are —NHCO—, L2 is —CONH—.

Abstract: A system and method of nanoparticle deposition for achieving an acetone sensitive response based on ruthenium decorated CuO nanowires at temperatures of 200° C. and 250° C. is disclosed. This method is useful for building sensors. The method used to build the sensor is easily integrable into silicon technology broadly, and into a CMOX compatible device specifically. Additionally, it is expected that this method of nanoparticle deposition can be transferred to other MOx nanowire sensors, such as but not limited to zinc oxide nanowire.

Abstract: Provided is an optical module comprising a substrate, a holder, and a spacer. An optical waveguide is formed in/on the substrate and end parts thereof are protruding from one surface of the substrate. The holder holds an optical fiber and exposes one end part of the optical fiber in such a manner that the one end part of the optical fiber can be optically connected to the end parts of the optical waveguide at a side of one surface of the holder. The spacer is held the one surface of the substrate and the one surface of the holder.

Abstract: This disclosure relates to generating interactive graphical visualisations of clinical and data. A processor calculates phenotype-to-phenotype similarity value indicative of a similarity between observed phenotypes and each phenotype in a set of stored phenotypes based on an ontology of phenotypes. The processor then determines an assignment of stored phenotypes to observed phenotypes based on the similarity values and further aggregates the similarity values into a set-to-set similarity value indicative of a similarity between the observed phenotypes and the set of stored phenotypes. The processor then repeats these steps to calculate a set-to-set similarity measure for each of the multiple sets. Finally, the processor selects one or more of the multiple sets based on the set-to-set similarity value and generates a graphical user interface comprising a graphical indication of the selected one or more of the multiple sets in relation to the multiple observed phenotypes.

Abstract: Provided is a precursor of a current-perpendicular-to-plane giant magnetoresistive element having a laminated structure of ferromagnetic metal layer/nonmagnetic metal layer/ferromagnetic metal layer, the precursor having a nonmagnetic intermediate layer containing a non-magnetic metal and an oxide in a predetermined ratio such that the distribution thereof is nearly uniform at the atomic level. Also provided is a current-perpendicular-to-plane giant magnetoresistive element having a current-confinement structure (CCP) which has: a current confinement structure region made of a conductive alloy and obtained by heat-treating a laminated structure of a ferromagnetic metal layer and a nonmagnetic intermediate layer at a predetermined temperature; and a high-resistance metal alloy region containing an oxide and surrounding the current confinement structure region.

Abstract: Selectively providing voltage-gated sodium channel function sufficient to rescue impaired Nav1.1 function to inhibitory neurons is described. Provided voltage-gated sodium channel function sufficient to rescue impaired Nav1.1 function in inhibitory neurons can be used to treat disorders such as epilepsy, and more particularly, Dravet Syndrome.

Abstract: The present invention provides a novel process for preparing an oligosaccharide C-glycoside derivative of formula I, comprising reacting a compound of formula II with compound of formula III in the presence of at least one primary or secondary amine and at least one additive [in the formulae, the substituents are as defined herein], and novel oligosaccharide C-glycoside derivatives that can be prepared using the process.

Abstract: A magnetically coupled ball drive system for actuation of spherical surfaces and wheels is disclosed. An internal support structure interacts with exterior drive wheels magnetically to produce rotational motion. A related improvement involving reduction of slip due to insufficient traction is also presented to establish a design for a more robust and versatile device that can be used in robotics or for producing vehicle locomotion.

Abstract: The present application provides bifunctional compounds which act as protein degradation inducing moieties. The present application also relates to methods for the targeted degradation of endogenous proteins through the use of the bifunctional compounds that link a cereblon-binding moiety to a ligand that is capable of binding to the targeted protein which can be utilized in the treatment of proliferative disorders. The present application also provides methods for making compounds of the application and intermediates thereof.

Abstract: The invention provides a dust repellant and anti-reflective inorganic coating and the method for preparing the coating. The dust repellant and anti-reflective inorganic coating includes nano-porous silica (SiO2) network of about 5 nm to about 35 nm and is characterized by cracks. The method of preparing the dust repellant and anti-reflective inorganic coating on a substrate includes mixing of aqueous SiO2 solution with a solvent. The aqueous SiO2 solution with the solvent is stirred to form a solution. The solution is coated on the substrate to form a film on the surface of the substrate. Thereafter, the film is annealed by heating the film to a temperature of about 500° C. to about 700° C. within a period of about 2 minutes to about 2 hours. Finally, the film is allowed to cool down.

Abstract: The present disclosure relates to a foot-and-mouth disease virus vaccine composition, especially a recombinant bivalent vaccine composition against type O and type A foot-and-mouth disease viruses. The present disclosure further relates to a method for preparing the foot-and-mouth disease virus vaccine composition, and a use of the foot-and-mouth disease virus vaccine composition in preparing medicines for preventing and/or controlling foot-and-mouth disease in animals.

Abstract: A method of inverse reinforcement learning for estimating cost and value functions of behaviors of a subject includes acquiring data representing changes in state variables that define the behaviors of the subject; applying a modified Bellman equation given by Eq. (1) to the acquired data: q(x)+gV(y)?V(x)=?ln{pi(y|x))/(p(y|x)} (1) where q(x) and V(x) denote a cost function and a value function, respectively, at state x, g represents a discount factor, and p(y|x) and pi(y|x) denote state transition probabilities before and after learning, respectively; estimating a density ratio pi(y|x)/p(y|x) in Eq. (1); estimating q(x) and V(x) in Eq. (1) using the least square method in accordance with the estimated density ratio pi(y|x)/p(y|x), and outputting the estimated q(x) and V(x).

Abstract: A surface-treated ceramic powder includes a plurality of ceramic particles and a surface-treating material. Each of the ceramic particles is at least partially coated by the surface-treating material, wherein the ceramic particles have an average particle diameter ranging from 10 micrometer (?m) to 100 ?m, and the surface-treating material is made of metal, metal oxide or the combination thereof.

Abstract: Provided is a sector discovery apparatus and method, the method including setting, by an AP in a WLAN system, an omni-beacon interval for transmitting an omnidirectional beacon and sector beacon intervals for transmitting a sector beacon with respect to one of a plurality of sectors which are spatially divided, transmitting the sector beacon to a current sector among the plurality of sectors, transmitting, to the current sector, a transmission frame indicating sectorized transmission or a transmission frame indicating omnidirectional transmission, in a sector interval between the sector beacon intervals, and receiving, from a terminal located in the current sector, a response frame indicating an association performed by receiving the transmission frame indicating the sectorized transmission.

Abstract: A method for generating a electro spun fiber medical implant including determining dimensions of a portion of anatomy of a patient corresponding to the electro spun fiber medical implant via medical imaging, generating a model of the portion of the anatomy based on the dimensions, the model including one or more solid areas and one or more void areas encompassed within the one or more solid areas, inverting the model to generate a mandrel model, the mandrel model generated based on the one or more void areas, generating the mandrel based on the mandrel model, the mandrel including at least one electrically conductive material therein, and applying an electro-spinning process to the mandrel to generate the electro spun fiber medical implant which circumscribes the mandrel, wherein the mandrel is removable from within the electro spun fiber medical implant after a disassembly process.