Patents Assigned to INSTITUTE
  • Patent number: 10874735
    Abstract: The present invention is directed to a method of manufacturing a polyepitopic protein comprising the steps of cloning a blunt-ended DNA sequence by encoding the epitope that is to be cloned into a DNA vector recognized by the endonuclease SmaI or the endonuclease SapI and isolating the polyepitopic protein by transforming a bacterial host cell with such vector.
    Type: Grant
    Filed: April 21, 2015
    Date of Patent: December 29, 2020
    Assignee: BIOVENTURES INSTITUTE SP. Z O. O.
    Inventors: Piotr Skowron, Agnieszka Zylicz-Stachula, Olga Zolnierkiewicz, Malgorzata Skowron, Lukasz Janus, Joanna Jezewska-Frackowiak, Daria Krefft, Dawid Nidzworski, Kasjan Szemiako, Natalia Maciejewska, Marta Nowak, Aneta Szymanska
  • Patent number: 10880475
    Abstract: Disclosed are a video conversion apparatus and a system for generating a 360-degree VR video in real time. The video conversion apparatus includes an input unit and a controller. The input unit receives a plurality of pieces of video information having continuity from a video recording apparatus including a plurality of cameras. The controller captures the plurality of pieces of video information received from the input unit, encodes the captured pieces of video information in a parallel structure, and stitches the encoded pieces of video information to generate a 360-degree VR video.
    Type: Grant
    Filed: December 13, 2019
    Date of Patent: December 29, 2020
    Assignee: KOREA ELECTRONICS TECHNOLOGY INSTITUTE
    Inventors: Junhwan Jang, Woochool Park, Youngwha Kim, Jinwook Yang, Sangpil Yoon, Hyunwook Kim, Eunkyung Cho, Minsu Choi, Junsuk Lee, Jaeyoung Yang
  • Publication number: 20200398245
    Abstract: Described are a low temperature plasma reaction device and a hydrogen sulfide decomposition method. The reaction device includes: a first cavity; a second cavity, the second cavity being embedded inside or outside the first cavity; an inner electrode, the inner electrode being arranged in the first cavity; an outer electrode; and a barrier dielectric arranged between the outer electrode and the inner electrode. The hydrogen sulfide decomposition method includes: implementing dielectric barrier discharge at the outer electrode and the inner electrode of the low temperature plasma reaction device, introducing a raw material gas containing hydrogen sulfide into the first cavity to implement a hydrogen sulfide decomposition method, and continuously introducing a thermally conductive medium into the second cavity in order to control the temperature of the first cavity of the low temperature plasma reaction device.
    Type: Application
    Filed: January 31, 2019
    Publication date: December 24, 2020
    Applicants: CHINA PETROLEUM & CHEMICAL CORPORATION, CHINA PETROLEUM & CHEMICAL CORPORATION QINGDAO RESEARCH INSTITUTE OF SAFEY ENGENEERING
    Inventors: Jing ZHANG, Shanjun MU, Wei XU, Ning SHI, Shucai ZHANG, Guosheng DONG, Tie ZHANG, Lin WANG, Junpeng REN, Feng SUN
  • Publication number: 20200398873
    Abstract: The present invention relates to a bogie structure for a mountain railway car. The bogie structure is configured as follows: a traction motor for driving an axle of mountain railway car is installed on a car body to simplify the bogie structure and to minimized interference between the traction motor and other components constituting the bogie, and a first and a second bearing are respectively inserted and installed between a first and a second axle and a first and a second wheel, so that a first and a second wheel located in one side close to a turning center are rotated less than a first and a second wheel located in the other side opposite thereof and a traveling distance of the wheels located in the turning-centered side is generated corresponding to a length of a turning-centered side railway, whereby the mountain railway car is improved in traveling stability.
    Type: Application
    Filed: June 22, 2017
    Publication date: December 24, 2020
    Applicant: KOREA RAILROAD RESEARCH INSTITUTE
    Inventors: SUNG-IL SEO, Hyung-Suk MUN
  • Publication number: 20200402526
    Abstract: A speech extraction method based on the supervised learning auditory attention includes: converting an original overlapping speech signal into a two-dimensional time-frequency signal representation by a short-time Fourier transform to obtain a first overlapping speech signal; performing a first sparsification on the first overlapping speech signal, mapping intensity information of a time-frequency unit of the first overlapping speech signal to preset D intensity levels, and performing a second sparsification on the first overlapping speech signal based on information of the preset D intensity levels to obtain a second overlapping speech signal; converting the second overlapping speech signal into a pulse signal by a time coding method; extracting a target pulse from the pulse signal by a trained target pulse extraction network; converting the target pulse into a time-frequency representation of the target speech to obtain the target speech by an inverse short-time Fourier transform.
    Type: Application
    Filed: April 19, 2019
    Publication date: December 24, 2020
    Applicant: INSTITUTE OF AUTOMATION, CHINESE ACADEMY OF SCIENCES
    Inventors: Jiaming XU, Yating HUANG, Bo XU
  • Publication number: 20200403531
    Abstract: The present disclosure provides a biomimetic mobile legged robot, which includes a body formed to extend in one direction and having a piezoelectric element, and a leg connected to intersect the body and having a piezoelectric element. Here, a power is supplied to the body and the leg, respectively, and the piezoelectric elements of the body and the leg are operated with the supplied power to cause a full body motion so that the legged robot moves.
    Type: Application
    Filed: December 12, 2019
    Publication date: December 24, 2020
    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventor: Youngsu CHA
  • Publication number: 20200399488
    Abstract: A particle composition according to the present invention contains: hydraulic alumina particles; and a water-absorbing polymer.
    Type: Application
    Filed: February 25, 2019
    Publication date: December 24, 2020
    Applicants: SUMITOMO CHEMICAL COMPANY, LIMITED, TOKYO INSTITUTE OF TECHNOLOGY
    Inventors: Toshiyuki IKOMA, Ryohei HAMANO, Satoshi YOKOI, Norifumi AZUMA, Kousuke UOE
  • Publication number: 20200397719
    Abstract: This application describes a compound represented by Formula (I): wherein: Y is a biologically active organic core group comprising one or more of an aryl group, a heteroaryl aryl group, a nonaromatic hydrocarbyl group, and a nonaromatic heterocyclic group, to which Z is covalently bonded; n is 1, 2, 3, 4 or 5; m is 1 or 2; Z is O, NR, or N; X1 is a covalent bond or —CH2CH2—, X2 is O or NR; and R comprises H or a substituted or unsubstituted group selected from an aryl group, a heteroaryl aryl group, a nonaromatic hydrocarbyl group, and a nonaromatic heterocyclic group. Methods of preparing the compounds, methods of using the compounds, and pharmaceutical compositions comprising the compounds are described as well.
    Type: Application
    Filed: September 4, 2020
    Publication date: December 24, 2020
    Applicant: THE SCRIPPS RESEARCH INSTITUTE
    Inventors: Jiajia DONG, K. Barry SHARPLESS, Jeffery W. KELLY, Aleksandra BARANCZAK, Wentao CHEN
  • Publication number: 20200399276
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of malaria.
    Type: Application
    Filed: June 29, 2020
    Publication date: December 24, 2020
    Applicant: THE BROAD INSTITUTE, INC.
    Inventors: EAMON COMER, NOBUTAKA KATO, CHRISTINA SCHERER, JESSICA BASTIEN, JEREMY DUVALL, TIMOTHY LEWIS, MORGANE SAYES, MATTHEW LEIGHTY, JUN PU, JENNIFER BEAUDOIN, BERTRAND BRAIBANT, BENITO MUNOZ
  • Publication number: 20200399390
    Abstract: The invention relates to a method for producing a lymphocyte progenitor, the method comprising culturing a pluripotent stem cell (PSC)-derived CD34+ cell at an air-liquid interface (ALI). The invention also relates to a method for producing a B-cell progenitor, the method comprising co-culturing a PSC-derived CD34+ cell and a stromal cell in a medium comprising a CD117 activator and a NOTCH1 inhibitor. The invention further relates to a T-cell progenitor and a B-cell progenitor when produced by the methods of the invention and to use of the T-cell progenitor in the manufacture of T cell with defined antigen specificity, optionally a chimeric antigen receptor (CAR) T cell, and use of the B-cell progenitor in the manufacture of an antibody.
    Type: Application
    Filed: March 8, 2018
    Publication date: December 24, 2020
    Applicant: MURDOCH CHILDRENS RESEARCH INSTITUTE
    Inventors: Edouard Guy STANLEY, Andrew ELEFANTY, Ali MOTAZEDIAN
  • Publication number: 20200403269
    Abstract: A method of manufacturing a lithium solid electrolyte, the method including: providing a composition including a lithium precursor, a lanthanum precursor, and a zirconium precursor; disposing the composition on a substrate having a temperature of 270° C. to 500° C. to form a film; and heat-treating the film at 300° C. to less than 750° C. for 1 hour to 100 hours to manufacture the lithium solid electrolyte.
    Type: Application
    Filed: April 28, 2020
    Publication date: December 24, 2020
    Applicants: SAMSUNG ELECTRONICS CO., LTD., MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Yuntong Zhu, Won Seok Chang, Jennifer Rupp, Lincoln Miara
  • Publication number: 20200404594
    Abstract: An operation method of a first terminal, performed in a communication system, may comprise receiving sidelink resource allocation information from a base station; receiving a first sidelink signal from a second terminal based on the sidelink resource allocation information; calculating a path loss experienced by the first sidelink signal based on the first sidelink signal; transmitting a second sidelink signal including information on the path loss experienced by the first sidelink signal to the second terminal; and receiving, from the second terminal, a third sidelink signal to which a sidelink transmit power determined based on the path loss is allocated.
    Type: Application
    Filed: June 17, 2020
    Publication date: December 24, 2020
    Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Go San NOH, Seon Ae KIM, IL GYU KIM, Jun Hyeong KIM, Hee Sang CHUNG, Dae Soon CHO, Sung Woo CHOI, Seung Nam CHOI, Jung Pil CHOI
  • Publication number: 20200401223
    Abstract: Provided is a bidirectional neural interface having excellent elasticity and electrical conductivity improved by deformation, and further having self-healability and a method of manufacturing the same. The bidirectional neural interface includes a first elastic substrate, a neural electrode disposed on the first elastic substrate and including a conductive polymer composite, and a second elastic substrate disposed on the neural electrode, wherein the conductive polymer composite includes a matrix formed of a self-healing polymer material, and a plurality of electrical conductor clusters distributed in the matrix, wherein each of the electrical conductor clusters includes particles of a first electrical conductor, and a plurality of particles of a second electrical conductor formed of the same material as that of the first electrical conductor, distributed around each of the particles of the first electrical conductor and having smaller sizes than sizes of the particles of the first electrical conductor.
    Type: Application
    Filed: June 15, 2020
    Publication date: December 24, 2020
    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Hyunseon SEO, Inchan YOUN, Hyojin LEE, Kang-Il SONG, Donghee SON
  • Publication number: 20200402686
    Abstract: The present invention provides a superconducting block, comprising, a pair of cores with materials that are electrically conductive in their normal states. The pair of cores are embedded in the shell with an intervening centroidal distance, with a material that is electrically conductive in its normal state. The embedded pair of cores and the shell are configured to be superconductive. The present invention also provides a superconducting nanocrystal with at least the superconducting block. The present invention also provides a superconductive device with at least the superconducting block and the superconducting nanocrystal. The present invention further provides a process for fabricating the superconducting block and superconducting crystal. The present invention provides superconductors (superconducting block, superconducting nanocrystals) that can be employed to attain superconductivity at high temperatures, corresponding to temperatures existing in the terrestrial ambient and even higher.
    Type: Application
    Filed: March 11, 2019
    Publication date: December 24, 2020
    Applicant: INDIAN INSTITUTE OF SCIENCE
    Inventors: Anshu PANDEY, Dev Kumar THAPA, Subham Kumar SAHA
  • Publication number: 20200401007
    Abstract: Provided is a display device. The display device includes a data line extending in a first direction, a reflective electrode on the data line, and a transistor formed between the data line and the reflective electrode. The transistor includes a first electrode connected to the data line, a second electrode spaced apart from the first electrode in the first direction and connected to the reflective electrode, and a semiconductor layer connecting the first electrode and the second electrode.
    Type: Application
    Filed: September 9, 2020
    Publication date: December 24, 2020
    Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventor: Ji Hun CHOI
  • Patent number: 10872131
    Abstract: A method of identifying insights related to the occurrence of an adverse health outcome of interest, comprises extracting electronic clinical data associated with historical healthcare encounters. The method also comprises defining patient groups based upon similar data patterns present in the extracted electronic clinical data wherein the patient groups have varying likelihood for the adverse health outcome. Still further, the method comprises deriving hypothesized etiological explanations for why one or more patient groups have higher likelihood when compared to other patient groups. Optionally, the method comprises identifying clinical interventions that are intended to reduce the likelihood of the adverse outcome for certain patient groups.
    Type: Grant
    Filed: October 26, 2018
    Date of Patent: December 22, 2020
    Assignee: BATTELLE MEMORIAL INSTITUTE
    Inventors: Steven W. Rust, Daniel Haber
  • Patent number: 10873117
    Abstract: A protective layer can be deposited on a surface of an porous polymer separator placing on a Li-metal electrode to protect against adverse electrochemical activity in a battery. The protective layer can be a multilayered structure including graphene oxide.
    Type: Grant
    Filed: December 30, 2013
    Date of Patent: December 22, 2020
    Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Paula T. Hammond, Sun Hwa Lee
  • Patent number: 10873031
    Abstract: Disclosed are a p-doped conjugated small molecular electrolyte containing a compound represented by Formula 1 and an organic electronic device using the same as a hole transport material. [Ar2—Ar1—Ar2]+??<Formula 1> wherein, in Formula 1, Ar1 is any one selected from the following Compound Group 1, Ar2 is any one selected from the following Compound Group 2a or the following Compound Group 2b, and superscript “+” in the square bracket indicates an oxidized portion of a main chain of the small molecule.
    Type: Grant
    Filed: December 23, 2015
    Date of Patent: December 22, 2020
    Assignee: GWANGJU INSTITUTE OE SCIENCE AND TECHNOLOGY
    Inventors: Kwanghee Lee, Seoung-Ho Lee, Jong-Hoon Lee, Song-Yi Jeong
  • Patent number: 10871429
    Abstract: The purpose of the present invention is to provide an injection apparatus and an injection method for a liquid sample for standard gas production, wherein the injection apparatus for injecting a liquid sample present in a liquid state at room temperature into a standard gas container has an improved structure that minimizes the area in which the liquid sample directly contacts the injection apparatus so as to prevent the problem in which the liquid sample is adsorbed into the injection apparatus. Furthermore, another purpose of the present invention is to provide an injection apparatus and an injection method for a liquid sample for standard gas production, in which a step of volatilizing the remaining liquid sample by heating is eliminated during the injection of the liquid sample, thereby preventing the apparatus from being damaged by heating to thereby improve the durability of the apparatus.
    Type: Grant
    Filed: July 13, 2018
    Date of Patent: December 22, 2020
    Assignee: KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE
    Inventors: Jihwan Kang, Yong-Doo Kim, Sangil Lee
  • Patent number: 10870636
    Abstract: The application relates to a compound having Formula (I): which modulates the activity of EGFR, a pharmaceutical composition comprising the compound, and a method of treating or preventing a disease in which EGFR plays a role.
    Type: Grant
    Filed: March 1, 2019
    Date of Patent: December 22, 2020
    Assignee: DANA-FARBER CANCER INSTITUTE, INC.
    Inventors: Nathanael S. Gray, Pasi Janne, Hwan Geun Choi, Jaebong Jang