Abstract: Described herein are peptides, compositions, and methods for diagnosing, detecting, imaging, monitoring, preventing, treating, or ameliorating diseases or disorders including cancer, inflammatory disorder, and autoimmune disease.

Abstract: In some aspects, the disclosure provides methods for modulating mitochondrial transport of serine in a cell, the methods comprising modulating expression or activity of one or more sideroflexins. In some aspects, methods of identifying agents that modulate sideroflexin expression or activity are provided. In some aspects, methods of treating cancer are provided.

Abstract: A water filtration membrane is provided, capable of removing heavy metal ions, filtering out particulates, filtering out bacteria, as well as removing herbicides and volatile organic compounds (VOCs) from water. The membrane is composed of a mat of randomly oriented nanoparticle-coated nanofibers. The nanofibers are covalently bonded to a plurality of substantially uniformly-distributed ceramic nanoparticles embedded in or adhered on the surface of the polymer nanofibers through reactive functional groups. The ceramic nanoparticles have a pattern of deep grooves formed on the nanoparticle surfaces. The bonding of the nanoparticles to the nanofibers is sufficient to retain the nanoparticles on the nanofiber surfaces when water flows through the water filtration membrane. The diameter of the nanofibers is 50-200 nm. The size of the nanoparticles is <40 nm, with a zeta potential of ?40 to ?45 mV in a dispersion medium. The nanoparticle deep grooves have an average size of approximately 1.2 nm or less.

Abstract: A high-entropy alloy having ultra-high strength and high hydrogen embrittlement resistance due to formation of a microstructure at a low strain may be produced without a severe plastic deformation. A method for producing the high-entropy alloy includes (a) annealing and homogenizing an initial alloy material at 1000 to 1200° C. for 1 to 24 hours; and (b) rolling the annealed and homogenized initial alloy material into a rod, at a cryogenic temperature of ?100 to ?200° C. while pressing the initial alloy material in multi-axial directions at a strain of 0.4 to 1.2, thereby to produce the high-entropy alloy having intersecting twins as a microstructure, and secondary fine twins formed in the intersecting twins, wherein the initial alloy material contains Co of 5 to 35%, Cr of 5 to 35%, Fe of 5 to 35%, Mn of 5 to 35%, and Ni of 5 to 35%, based on weight %.

Abstract: There is provided a cloud management method and apparatus for performing load balancing so as to make a service in a cluster that is geographically close in an associative container environment and has a good resource current status. The cloud management method according to an embodiment includes: monitoring, by a cloud management apparatus, available resource current statuses of a plurality of clusters, and selecting a cluster that owns a first service supported by a first cluster an available resource rate of which is less than a threshold value; calculating, by the cloud management apparatus, scores regarding an available resource current status and geographical proximity of each cluster; and performing, by the cloud management apparatus, load balancing of the first service, based on a result of calculating the scores.

Abstract: Provided herein are methods for evaluating tumor cell spheroids in a three-dimensional microfluidic device by determining changes in the relative levels of live cells and dead cells in aliquots cultured under different conditions. Methods described herein allow ex vivo recapitulation of the tumor microenvironment such that the in vivo effectiveness of a test compound in treating tumor tissue may be predicted.

Abstract: A credibility evaluation device for evaluating a credibility of a user who uses a service provided by a communicable structure includes a processor including hardware. The processor is configured to: acquire structure information on the structure during and after use of the service by the user and third-party evaluation information including evaluation about the structure made by a third party other than the user after use of the service by the user; and calculate the credibility of the user, based on at least one of the structure information and the third-party evaluation information.

Abstract: This invention discloses a practical method for landslide detection in large space, which comprises the following steps: image synthesis, ice and snow detection, removal of non-potential landslide area, detection of potential landslide area, feature calculation, landslide detection model construction and precision validation; this invention avoids radiometric correction and outlier by detecting landslide from synthetic image. That guarantees practical applicability of the proposal. Firstly, detecting potential landslides can avoid the imbalanced sample distribution issue between background objects and landslides when training the landslide detection model. The landslide is further detected by building a random forest model based on the spectral features and textural features of potential landslide pixels in different neighboring time domains. It fully considers the changes of objects in different time domains, and lays a foundation for efficient landslide extraction.

Abstract: A composition for targeting low-density lipoprotein receptor-related protein 6 (LRP6)-overexpressed cells. The composition includes a peptide including at least one of SEQ ID NO: 1 and SEQ ID NO: 3.

Abstract: The systems and methods described herein determine metrics of cardiac or vascular performance, such as cardiac output, and can use the metrics to determine appropriate levels of mechanical circulatory support to be provided to the patient. The systems and methods described determine cardiac performance by determining aortic pressure measurements (or other physiologic measurements) within a single heartbeat or across multiple heartbeats and using such measurements in conjunction with flow estimations or flow measurements made during the single heartbeat or multiple heartbeats to determine the cardiac performance, including determining the cardiac output. By utilizing a mechanical circulatory support system placed within the vasculature, the need to place a separate measurement device within a patient is reduced or eliminated. The system and methods described herein may characterize cardiac performance without altering the operation of the heart pump (e.g., without increasing or decreasing pump speed).

Abstract: A fiber masterbatch including a polyetherimide, a polyethylene terephthalate, and a polyimide is provided. A glass transition temperature of the polyimide is between 140° C. and 170° C., a 10% thermogravimetric loss temperature of the polyimide is between 500° C. and 550° C., and when the polyimide is dissolved in N-methyl-2-pyrrolidone and a solid content of the polyimide is 15 wt %, a viscosity of the polyimide is between 80 cP and 230 cP. A melt spun fiber obtained by using the fiber masterbatch is also provided.

Abstract: A video signal decoding device comprises a processor, wherein: the processor decodes a sequence parameter set (SPS) raw byte sequence payload (RBSP) syntax included in a bitstream of a video signal, and decodes the bitstream on the basis of the decoding result of the SPS RBSP syntax; the SPS RBSP syntax includes a first syntax element related to the number of one or more sub-pictures configuring one picture, and a second syntax element indicating whether to process a boundary of the one or more sub-pictures as a boundary of the one picture on the basis of the first syntax element; and the second syntax element is parsed only when the number of the one or more sub-pictures is two or more.

Abstract: A building envelope, in particular a wall, a floor, or a roof of a building with at least two shells spaced some distance apart from one another, which encloses an intermediate space, said space being essentially empty with the exception of weight-bearing and/or construction-engineering elements or being filled at least in sections with porous, open-celled material and sealed from the interior and exterior of the building, wherein controllable sealing means are provided for sealing the intermediate space from the interior and exterior and optionally separated building envelope sections from one other.

Abstract: A non-transitory, computer-readable recording medium stores a program of reinforcement learning by a state-value function. The program causes a computer to execute a process including calculating a temporal difference (TD) error based on an estimated state-value function, the TD error being calculated by giving a perturbation to each component of a feedback coefficient matrix that provides a policy; calculating based on the TD error and the perturbation, an estimated gradient function matrix acquired by estimating a gradient function matrix of the state-value function with respect to the feedback coefficient matrix for a state of a controlled object, when state variation of the controlled object in the reinforcement learning is described by a linear difference equation and an immediate cost or an immediate reward of the controlled object is described in a quadratic form of the state and an input; and updating the feedback coefficient matrix using the estimated gradient function matrix.

Abstract: The present invention provides a method of detecting Staphylococcus aureus in a subject, by contacting a sample obtained from the subject with at least one detectably labeled probe of the invention or detecting in the sample identity to a sequence of the invention. The invention is also directed to kits, microarrays and detectable Staphylococcus aureus polynucleotide probes useful in detecting the presence of Staphylococcus aureus.

Abstract: An electromagnetic property measuring device includes a magnetic conductive structure, a coil, and a scattering parameter measuring unit. The magnetic conductive structure includes a first side facing a sample to be tested and a second side opposite to the first side, and the first side has a magnetic gap. The coil surrounds the magnetic conductive structure to generate a magnetic field with the magnetic conductive structure. The scattering parameter measuring unit is disposed at the first side and located within a range of the magnetic field.

Abstract: Disclosed herein are methods for inhibiting or activating the transcription of a gene of interest, or inhibiting or activating the transcription of specific mRNA isoforms of a gene by using antisense oligonucleotides and/or small molecules. Also described herein are methods for activating transcription from a promoter and increasing overall gene expression by creating of a new splice site in a gene of a cell.

Abstract: The present invention relates to a method for identifying a chemical structure of a wide variety of low molecular weight compounds using mass-to-charge ratio and collision cross section of fragment ions of an analyte compound. The analyte compound is ionized and fragmented, and the fragment ions are measured by a mass spectrometer with an ion mobility spectrometry measurement device. According to the present method, it does not depend on any compound class-specific characteristics or structural features, therefore enabling determinations of any classes of low molecular weight compounds, which does not limit to a specific compound class. The present invention comprises three methods which share a common data structure and s data processing method.

Abstract: Disclosed are a photoelectrochemical electrode and a method of manufacturing the same, which enable mass production at low cost. The photoelectrochemical electrode manufactured by forming a transition metal dichalcogenide layer on all or part of the surface of a porous substrate includes a porous substrate and a metal dichalcogenide layer on all or part of the surface of the porous substrate, thus improving photoelectrode characteristics and photocatalytic efficiency.

Abstract: Disclosed herein are an apparatus and method for detecting a keypoint based on deep learning robust to scale changes based on information change across receptive fields. The apparatus for detecting a keypoint based on deep learning robust to scale changes based on information change across receptive fields includes a feature extractor for extracting a feature from an input image based on a pre-trained deep learning neural network, an information accumulation pyramid module for outputting, from the feature, at least two filter responses corresponding to receptive fields having different scales, an information change detection module for calculating an information change between the at least two filter responses, a keypoint detection module for creating a score map having a keypoint probability of each pixel based on the information change, and a continuous scale estimation module for estimating a scale of a receptive field having a biggest information change for each pixel.