Abstract: An automated craniotomy opening apparatus includes a drilling apparatus with a drilling tip, at least one drilling apparatus positioning device, a detection device, and a computer processor that automatically controls the drilling apparatus, the positioning device, and the detection device. A method for automated opening of craniotomies includes, under automatic control of a computer processor, drilling into a skull for a predetermined distance and determining when there is a conductance drop near the drilling tip that indicates skull breakthrough. If the conductance is not below a predetermined threshold, drilling continues iteratively manner until conductance is below the threshold. A craniotomy pattern may be predetermined and automatically drilled under control of the processor. A cranial window may be created by drilling along a path that interpolates between holes to form the circumference of the window. Determining conductance may include use of an impedance detection circuit.

Abstract: The application discloses an AI real-time microseism monitoring node, which includes a processor and a data acquisition device, an AI calculation device, and a communication device connected to the processor, wherein the AI calculation device is provided with pre-trained microseism data analysis Device, and the processor is configured to perform the following operations: controlling the data acquisition equipment to acquire microseism data; turning on the AI calculation device to calculate the acquired microseism data by means of the microseism data analysis device to determine the valid event data associated with the microseism; and sending the valid event data to the remote data center through the communication device.

Abstract: The disclosure provides methods and compositions that are useful to lessen and/or cure bacterial biofilms and treat diseases or disorders associated with biofilms using one or more novel polypeptide vaccines, antibodies, antibody fragments and compositions. Bacteria that cannot form functional biofilms are more readily cleared by the remainder of the host's immune system and/or traditional antibiotics.

Abstract: The present invention relates to a catalyst composition comprising a gold nanoparticle superlattice embedded in hierarchical porous silica and a method for manufacturing the same. The catalyst composition comprising a gold nanoparticle superlattice embedded in hierarchical porous silica according to the present invention comprises micropores and mesopores in the superlattice, so that these pores are channelized to allow the rapid access of reactants to surfaces of gold nanoparticles, and the catalyst composition is very structurally stable and has excellent catalytic activity, and thus has an effect of exhibiting a CO conversion rate of 100% at room temperature.

Abstract: This disclosure relates to methods and systems for processing of sequencing data streams. The system receives sequences from a sequencer and stores them as data records on a database. The sequences are associated with a counter indicative of a number of times the associated sequence has been sequenced. The system progressively receives a further sequence as streaming data from the sequence. While receiving the further sequence, the system matches the streaming data against the stored sequences to determine a matching score. Upon the matching score exceeding a matching threshold for one of the multiple sequences in the database, the system selects the one of the sequences in the database based on the matching score and stores the further sequence on non-volatile memory where the counter value associated with the selected sequence is below a saturation threshold. The system also terminates the receiving where the counter value is above the saturation threshold.

Abstract: The present invention provides soluble single wall nanotube (SWNT) constructs functionalized with a plurality of a targeting moiety and a plurality of one or more payload molecules attached thereto. The targeting moiety and the payload molecules may be attached to the soluble SWNT via a DNA or other oligomer platform attached to the SWNT. These soluble SWNT constructs may comprise a radionuclide or contrast agent and as such are effective as diagnostic and therapeutic agents. Methods provided herein are to diagnosing or locating a cancer, treating a cancer, eliciting an immune response against a cancer or delivering an anticancer drug in situ via an enzymatic nanofactory using the soluble SWNT constructs.

Abstract: Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients, are provided. Certain of the systems and methods described herein are capable of manufacturing multiple chemical products without the need to fluidically connect or disconnect unit operations when switching from one making chemical product to making another chemical product.

Abstract: A method and apparatus for sound enhancement are provided in this invention. The method comprises: obtaining sound signals and converting the sound signals into digital signals; decomposing the digital signals to obtain a plurality of IMFs or pseudo-IMFs; selectively amplifying the amplitudes of the IMFs and pseudo-IMFs; reconstituting the selectively amplified IMFs or pseudo-IMFs to obtain reconstituted signals and converting the reconstituted signals into analog signals. The present invention is based on the Hilbert-Huang transform. Through the present invention, the sound can be selectively amplified, and only the high-frequency consonants in the sound are amplified without vowel, which effectively improves the clarity of the enhanced sound. The present invention overcomes the problems in the current sound enhancement method which makes the sound louder without increasing the clarity.

Abstract: The present disclosure relates to a polymer electrolyte membrane for medium and high temperature, a preparation method thereof and a high-temperature polymer electrolyte membrane fuel cell including the same, more particularly to a technology of preparing a composite membrane including an inorganic phosphate nanofiber incorporated into a phosphoric acid-doped polybenzimidazole (PBI) polymer membrane by adding an inorganic precursor capable of forming a nanofiber in a phosphoric acid solution when preparing phosphoric acid-doped polybenzimidazole and using the same as a high-temperature polymer electrolyte membrane which is thermally stable even at high temperatures of 200-300° C. without degradation of phosphoric acid and has high ion conductivity.

Abstract: The present invention relates to a composition comprising as an active ingredient a strain having excellent ability to produce formic acid for preventing or treating obesity or metabolic syndromes caused by obesity; and to a food composition and a health functional food each comprising the active ingredient. The strain having excellent ability to produce formic acid according to the present invention not only has effects of reducing body weight and inhibiting fat accumulation in organs, but also has activity to effectively lower blood triglyceride and cholesterol levels, and therefore, the composition comprising the strain as an active ingredient can be favorably used as a composition capable of preventing/alleviating or treating obesity or metabolic syndromes caused by obesity. Therefore, the strain having excellent ability to produce formic acid according to the present invention can be favorably used as a material for a medical product or health food.

Abstract: A read-out circuit and a read-out method for a three-dimensional memory, comprises a read reference circuit and a sensitive amplifier, the read reference circuit produces read reference current capable of quickly distinguishing reading low-resistance state unit current and reading high-resistance state unit current. The read reference circuit comprises a reference unit, a bit line matching module, a word line matching module and a transmission gate parasitic parameter matching module. With respect to the parasitic effect and electric leakage of the three-dimensional memory in the plane and vertical directions, the present invention introduces the matching of bit line parasite parameters, leakage current and transmission gate parasitic parameters into the read reference current, and introduces the matching of parasitic parameters of current mirror into the read current, thereby eliminating the phenomenon of pseudo reading and reducing the read-out time.

Abstract: Disclosed is a multifunctional continuous hydrothermal oxidation experiment system, comprising a reactor (12), wherein an inlet of the reactor (12) is connected in parallel with an oxidant pipeline and a material pipeline; the oxidant pipeline comprises a gas oxidant delivery pipe and a liquid oxidant delivery pipe connected in parallel, and the gas oxidant pipe comprises an air oxidant delivery pipe and an oxygen delivery pipe connected in parallel; and a heat exchanger and a preheater are sequentially connected in series on the oxidant pipeline and the material pipeline, the oxidant pipeline and the material pipeline are in communication with an inner pipe of the heat exchanger; and the outlet of the reactor (12) is sequentially in communication, by means of piping, with a corrosion experiment device (14), an outer pipe of the heat exchanger, a cooler (16) and a gas-liquid separator (17).

Abstract: A method for manufacturing an aluminum circuit board including a step of spraying a heated metal powder containing aluminum particles and/or aluminum alloy particles to a ceramic base material, and of forming a metal layer on a surface of the ceramic base material. A temperature of at least a part of the metal powder is higher than or equal to a softening temperature of the metal powder and lower than or equal to a melting point of the metal powder at a time point of reaching the surface of the ceramic base material. A velocity of at least a part of the metal powder is greater than or equal to 450 m/s and less than or equal to 1000 m/s at the time point of reaching the surface of the ceramic base material.

Abstract: The present invention relates to a flexible pressure sensor using a multi-material 3D-printed microchannel mold, and a method for manufacturing the same. An object of the present invention is to provide a flexible pressure sensor using a multi-material 3D-printed microchannel mold, the flexible pressure sensor being formed by using a conductive liquid and an elastomer, having a microchannel formed therein, and having improved flexibility, sensitivity, and stability in comparison to the related art. Another object of the present invention is to provide a method for manufacturing a flexible pressure sensor using a multi-material 3D-printed microchannel mold, in which the flexible pressure sensor is manufactured by using the microchannel mold including microbumps, the microchannel mold being multi-material 3D-printed by using a sacrificial material and a hard material.

Abstract: The invention relates to a modular integrated construction joint which includes a first building module, a second building module or a structural wall and a joint between the first building module and the second building module or structural wall. The joint includes a flexible seamless stitching system, which provides a long-term firestop, smokestop and waterproof for the joint cavity in-between modules in modular integrated construction (MiC).

Abstract: The present disclosure provides new and innovative systems and methods for filtering encrypted messages. In an example, a computer-implemented method includes obtaining a message, determining sender profiling features of the message, determining enterprise graph features of the message, determining header features of the message, determining a message flag based on the sender profiling features, the enterprise graph features, and the header features, and processing the message based on the message flag.

Abstract: A highly integrated pattern-variable multi-antenna array, including a ground conductor structure, a first antenna array, a second antenna array, and an array conjoined grounding structure, is provided. A first inverted L-shaped resonant structure has a first feeding point, and the others respectively have a first switch and are electrically connected or coupled to the ground conductor structure. A second inverted L-shaped resonant structure has a second feeding point, and the others respectively have a second switch and are electrically connected or coupled to the ground conductor structure. The first and second antenna arrays respectively generate first and second resonance modes. The second and first resonance modes cover at least one same first communication frequency band.

Abstract: A system and method for monitoring characteristics of an electric energy device includes generating an external short from the electric energy device. The external short occurs at a known distance from a sensor and has at least one known external resistance. The received signal representing change in electromagnetic field due to the applied external short may be analyzed to determine a signal parameter that is then analyzed in comparison to a lookup table, based on the known conditions including distance, temperature and the external resistance. The output of this analyses in comparison with expected values may be utilized to identify a characteristic of the energy device.

Abstract: The invention relates to a scintillation material of rare earth orthosilicate doped with a strong electron-affinitive element and its preparation method and application thereof. The chemical formula of the scintillation material of rare earth orthosilicate doped with the strong electron-affinitive element is: RE2(1?x?y+?/2)Ce2xM(2y??)Si(1??)M?O5. In the formula, RE is rare earth ions and M is strong electron-affinitive doping elements; the value of x is 0<x?0.05, the value of y is 0<y?0.015, and the value of ? is 0???10?4; and M is selected from at least one of tungsten, lead, molybdenum, tellurium, antimony, bismuth, mercury, silver, nickel, indium, thallium, niobium, titanium, tantalum, tin, cadmium, technetium, zirconium, rhenium, and gallium Ga.

Abstract: A method of forming dialkyl carbonate is provided, which includes introducing carbon dioxide into a catalyst to form dialkyl carbonate, wherein the catalyst is formed by activating a catalyst precursor using alcohol, wherein alcohol is R3—OH, and R3 is C1-12 alkyl group or C5-12 aryl or heteroaryl group. The catalyst precursor is formed by reacting Sn(R1)2(L)2 and Ti(OR2)4, and Sn(R1)2(L)2 and Ti(OR2)4 have a molar ratio of 1:2 to 2:1. R1 is C1-10 alkyl group, R2 is H or C1-12 alkyl group, and L is O—(C?O)—R5, and R5 is C1-12 alkyl group.