Patents Assigned to INSTITUTE
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Patent number: 11517615Abstract: Recurrent tonsillitis disease (RT) is a common indication for pediatric tonsillectomy, the most frequent childhood surgery. It is unknown why some children develop RT. The present disclosure demonstrates that RT tonsils exhibit significantly smaller germinal centers than non-RT tonsils, concomitant with a bias against Group A Streptococcus (GAS)-specific germinal center follicular helper CD4+ T cells (GC Tfh), and significantly reduced antibodies to the GAS virulence factor SpeA. The present disclosure also shows a significant immunogenetic component to this disease, with the identification of ‘at risk’ and ‘protective’ HLA alleles for RT. Finally, the present disclosure identifies a new cell type, granzyme B+GC Tfh cells, which are activated by SpeA, are significantly more abundant in RT GC Tfh cells, and have the capacity to kill B cells, thus, providing a window into the immunology and genetics of a classic childhood disease and identifies a new type of pathogenic T cell.Type: GrantFiled: May 3, 2018Date of Patent: December 6, 2022Assignee: LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGYInventors: Shane Crotty, Jennifer Dan
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Patent number: 11523352Abstract: A transmit power indication method, a transmit power receiving method, a network device and an access device are provided. The transmit power indication method is applied to a network device, and includes transmitting indication information on a first link of the network device, wherein the indication information is used to indicate current transmit power of the first link of the network device, or to indicate a transmit power offset of the first link, wherein the transmit power offset is a difference between the current transmit power of the first link and transmit power of the network device before the network device transmits the indication information.Type: GrantFiled: June 27, 2019Date of Patent: December 6, 2022Assignees: China Mobile Communication Co., Ltd Research Institute, China Mobile Communications Group Co., Ltd.Inventors: Yi Zheng, Dan Wu, Jing Dong, Xueying Hou
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Patent number: 11523389Abstract: An operation method of a first distributed terminal, in a synchronized wireless distributed communication system which has a plurality of communication resources configured with a plurality of channels having different center frequencies and includes the first distributed terminal and a second distributed terminal, may comprise receiving slots mapped to the communication resources in a resource allocation channel having a center frequency independent from the plurality of channels; measuring communication environments of the communication resources by using a mapping relationship between the received slots of the resource allocation channel and the communication resources; selecting a first communication resource to be allocated using the measured communication environments of the communication resources; allocating the selected first communication resource; and continuously occupying the allocated first communication resource.Type: GrantFiled: September 25, 2020Date of Patent: December 6, 2022Assignee: Electronics and Telecommunications Research InstituteInventor: Hyun Gu Hwang
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Patent number: 11518980Abstract: Disclosed are compositions and methods for ex vivo expansion of tumor-infiltrating lymphocytes for use in adoptive cell therapy (ACT). Also disclosed are compositions and method for identifying an agent for ex vivo expansion of tumor-infiltrating lymphocytes for use in ACT. Also disclosed are methods for treating cancer using tumor-infiltrating lymphocytes expanded by the disclosed methods.Type: GrantFiled: February 11, 2019Date of Patent: December 6, 2022Assignees: H. Lee Moffitt Cancer Center and Research Institute, Inc., University of South FloridaInventors: Amod A. Sarnaik, Shari Pilon-Thomas, Mark McLaughlin, Hao Liu
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Patent number: 11517886Abstract: A modified Y-type molecular sieve has a modifying metal content of about 0.5-6.3 wt % calculated on the basis of an oxide of the modifying metal and a sodium content of no more than about 0.5 wt % calculated on the basis of sodium oxide. The modifying metal is magnesium and/or calcium. The modified Y-type molecular sieve has a proportion of non-framework aluminum content to the total aluminum content of no more than about 20%, a total pore volume of about 0.33-0.39 ml/g, a proportion of the pore volume of secondary pores having a pore size of 2-100 nm to the total pore volume of about 10-25%, a lattice constant of about 2.440-2.455 nm, a lattice collapse temperature of not lower than about 1040° C., and a ratio of B acid to L acid in the total acid content of no less than about 2.30.Type: GrantFiled: June 27, 2019Date of Patent: December 6, 2022Assignees: CHINA PETROLEUM & CHEMICAL CORPORATION, RESEARCH INSTITUTE OF PETROLEUM PROCESSING, SINOPECInventors: Shuai Yuan, Lingping Zhou, Huiping Tian, Zhenyu Chen, Weilin Zhang, Hao Sha
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Patent number: 11519023Abstract: There is provided a paper-based colorimetric sensor kit for quickly and simply diagnosing mercury in situ with a naked eye. The paper-based colorimetric sensor kit includes: a circular template for rolling circle amplification (RCA); a primer that does not hybridize to the circular template when a mercury ion is bonded to a primer that hybridizes to the circular template; a DNA polymerase; a sensing material kit including a nanoparticle probe labeled to a DNA coil formed in the circular template for RCA; and a radial chromatography paper.Type: GrantFiled: December 27, 2018Date of Patent: December 6, 2022Assignee: KOREA FOOD RESEARCH INSTITUTEInventors: Min-Ah Woo, Min-Cheol Lim, Sung-Wook Choi, Tai-Yong Kim
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Patent number: 11518949Abstract: A process for producing propylene and a low-sulfur fuel oil component, comprising the steps of contacting a heavy feedstock oil with a solvent for extraction separation to obtain a deasphalted oil and a deoiled asphalt; contacting the deasphalted oil and optionally a light feedstock oil with a catalytic conversion catalyst for reaction to obtain a reaction product comprising propylene; separating the reaction product to obtain a catalytic cracking distillate oil, and subjecting the catalytic cracking distillate oil to hydrodesulfurization to obtain a low-sulfur hydrogenated distillate oil, wherein the low-sulfur hydrogenated distillate oil and/or the deoiled asphalt is suitable for use as a fuel oil component. The process allows the conversion of saturated hydrocarbons in the heavy feedstock into propylene, eliminates the use of saturated hydrocarbons in the fuel oil component, and thus has better economic and social benefits.Type: GrantFiled: October 26, 2020Date of Patent: December 6, 2022Assignees: CHINA PETROLEUM & CHEMICAL CORPORATION, RESEARCH INSTITUTE OF PETROLEUM PROCESSING, SINOPECInventors: Youhao Xu, Xuhui Bai, Xinyu Xie, Shouye Cui, Xin Wang, Yanfen Zuo
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Patent number: 11519952Abstract: An embodiment of the present disclosure provides an arc detection method, in which an apparatus detects arcs, comprising the steps of: obtaining time series data for measured values of an electric current flowing in a wire; calculating first statistical values indicating dispersion degrees with time of the measured values or dispersion degrees with time of variances of the measured values from the time series data; and determining that an arc occurs in the wire or that the possibility of arc occurrence in the wire is high in a case when at least one of the first statistical values is out of a predefined range.Type: GrantFiled: October 14, 2021Date of Patent: December 6, 2022Assignee: KOREA INSTITUTE OF ENERGY RESEARCHInventors: Su Yong Chae, Mo Se Kang, Kuk Yeol Bae, Suk In Park, Hak Geun Jeong, Gi Hwan Yoon
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Patent number: 11518408Abstract: A driver monitor system and method for predicting impairment of a user of a vehicle. The system includes video cameras, an input device for inputting a list of medications being taken by the driver. Processing circuitry predicts side effects of the medications based on the half-life of the medication, detecting eye gaze movement, eye lid position, and facial expression of the user using images from the video camera, predicting whether the user is transitioning into an impaired physical state that is a side effect of the medications, verifying the side effect of the medications, determining whether the user is fit to drive using the verified side effects of the medications, and outputting to the vehicle an instruction to operate the vehicle in a level of automation that makes up for the at least one side effect or to perform a safe pull over operation of the vehicle.Type: GrantFiled: November 13, 2020Date of Patent: December 6, 2022Assignee: TOYOTA RESEARCH INSTITUTE, INC.Inventors: Nikos Arechiga-Gonzalez, Soonho Kong, Jonathan Decastro, Frank Permenter, Dennis Park
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Patent number: 11521048Abstract: The present invention relates to a weight management method and system for neural network processing. The method includes two stages, i.e., off-chip encryption stage and on-chip decryption stage: encrypting trained neural network weight data in advance, inputting the encrypted weight into a neural network processor chip, and decrypting the weight in real time by a decryption unit inside the neural network processor chip to perform related neural network calculation. The method and system realizes the protection of weight data without affecting the normal operation of a neural network processor.Type: GrantFiled: March 22, 2018Date of Patent: December 6, 2022Assignee: Institute of Computing Technology, Chinese Academy of SciencesInventors: Yinhe Han, Haobo Xu, Ying Wang
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Patent number: 11521066Abstract: A processor partitions a deep neural network having a plurality of exit points and at least one partition point in a branch corresponding to each of the exit points, for distributed processing in an edge device and a cloud. The processor sets environmental variables and training variables for training, selects an action to move at least one of an exit point and a partition point from a combination of the exit point and the partition point corresponding to a current state, performs the training by accumulating experience data using a reward according to the selected action and then moves to a next state, and outputs a combination of an optimal exit point and a partition point as a result of the training.Type: GrantFiled: March 25, 2020Date of Patent: December 6, 2022Assignee: Electronics and Telecommunications Research InstituteInventors: Chang Sik Lee, Sung Back Hong, Seungwoo Hong, Ho Yong Ryu
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Patent number: 11521073Abstract: A method is provided for hyperspectral inversion of a phosphorus content of rubber tree leaves. The method includes: acquiring hyperspectral data of to-be-detected rubber tree leaves; extracting key wavelengths of the rubber tree leaves according to the hyperspectral data and a pre-established wavelength extraction model, where the key wavelengths are related to the phosphorus content of the rubber tree leaves, and the pre-established wavelength extraction model is obtained by learning and training hyperspectral sample data and sample phosphorus content data pairs in a pre-established sample database by adopting a competitive adaptive reweighted sampling (CARS) algorithm and a successive projection algorithm (SPA); and inputting the key wavelengths into a pre-established phosphorus content prediction model to calculate the phosphorus content of the to-be-detected rubber tree leaves.Type: GrantFiled: April 1, 2020Date of Patent: December 6, 2022Assignees: RUBBER RESEARCH INSTITUTE, CHINESE ACADEMY OF TROPICAL AGRICULTURAL SCIENCES, INSTITUTE OF SCIENTIFIC AND TECHNICAL INFORMATION, CHINESE ACADEMY OF TROPICAL AGRICULTURAL SCIENCESInventors: Pengtao Guo, Maofen Li, Zhengzao Cha, Hongzhu Yang, Meirong Bei, Peisong Zhang, Wei Luo, Wei Yao
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Patent number: 11520951Abstract: The present invention relates to a method for evaluating an ecological environmental impact of a channel project and countermeasures thereof based on mechanism analysis, belonging to the field of ecological environmental impact evaluation technologies. In view of limitations of an existing evaluation method and the void of related technologies, the method includes: a project construction verification and change analysis method, a method for analyzing a fine classification impact mechanism and countermeasures thereof, a method for establishing a multi-level comprehensive index system of ecological environmental impacts, a method for establishing a compliance evaluation index system of an ecological channel, a method for tracking, monitoring and evaluation based on long-term time series satellite remote sensing and a method for analyzing and evaluating a superimposed and cumulative impact model.Type: GrantFiled: March 18, 2020Date of Patent: December 6, 2022Assignee: China Waterborne Transport Research InstituteInventors: Bing Qiao, Chunling Liu, Xuan Wu, Jinpeng Li, Xueyuan Ji, Mingbo Chen, Shiyue Wang, Yue Li
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Patent number: 11522117Abstract: A hybrid quantum system performs high-fidelity quantum state transduction between a superconducting (SC) microwave qubit and the ground state spin system of a solid-state artificial atom. This transduction is mediated via an acoustic bus connected by piezoelectric transducers to the SC microwave qubit. For SC circuit qubits and diamond silicon vacancy centers in an optimized phononic cavity, the system can achieve quantum state transduction with fidelity exceeding 99% at a MHz-scale bandwidth. By combining the complementary strengths of SC circuit quantum computing and artificial atoms, the hybrid quantum system provides high-fidelity qubit gates with long-lived quantum memory, high-fidelity measurement, large qubit number, reconfigurable qubit connectivity, and high-fidelity state and gate teleportation through optical quantum networks.Type: GrantFiled: January 19, 2021Date of Patent: December 6, 2022Assignees: Massachusetts Institute of Technology, President and Fellows of Harvard College, National Tech. & Eng. Solutions of Sandia, LLCInventors: Dirk Robert Englund, Matthew Edwin Trusheim, Matt Eichenfield, Tomas Neuman, Prineha Narang
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Patent number: 11516979Abstract: The present invention relates to a method for conducting high-throughput and directed mutagenesis for sugarcane resistance to glyphosate by plasma. The method is as follows: sugarcane embryonic calli are irradiated by a plasma instrument under a sterile condition for mutagenesis, wherein the mutagenesis power is 140˜200 W, the discharging distance is 35˜45 mm, the mutagenesis time is 110˜140 s and the protective gas is nitrogen; buffering culture, moderate/high concentration of glyphosate stress screening, differentiation into seedlings, glyphosate stress screening of bottle seedlings and stress screening via spraying glyphosate on the leave surfaces of potted plants are conducted for the treated calli. The present invention has the advantages of safe operation, simplicity, practicability, high handling capacity, low contamination, and due to implementation of directed stress screening, high screening efficiency, decreased subsequent screening workload and visual identification of resistant mutant strains.Type: GrantFiled: October 27, 2017Date of Patent: December 6, 2022Assignee: INSTITUTE OF NANFAN & SEED INDUSTRY, GUANGDONG ACADEMY OF SCIENCESInventors: Zhongxing Huang, Donglei Sun, Yuanxian Xu, Huiyi He, Lina Fan, Fangye Lao, Qiuping Ling, Yuxing An
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Patent number: 11521777Abstract: A demagnetization method for a multilayer shielding apparatus is provided. In the demagnetization method, the demagnetization is realized on the basis of a demagnetization coil system. The demagnetization coil system includes a plurality of turns of demagnetization coils (2), a plurality of connection wires and a power supply module. The multilayer shielding apparatus includes at least two layers of shielding bodies (1); all the layers of shielding bodies (1) are sleeved layer by layer from inside to outside; a plurality of turns of demagnetization coils (2) are wound on each layer of shielding bodies (1) at intervals; and one half of each turn of demagnetization coils (2) is located inside the wound shielding bodies (1), and the other half is located outside the wound shielding bodies (1). Each demagnetization coil (2) is connected to the power supply module through the corresponding connection wire.Type: GrantFiled: March 21, 2022Date of Patent: December 6, 2022Assignee: HARBIN INSTITUTE OF TECHNOLOGYInventors: Zhiyin Sun, Liyi Li, Donghua Pan, Kai Song, Yuxi Liu, Yinxi Jin, Zhilong Zou
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Patent number: 11523429Abstract: Embodiments herein provide a method and system for managing Grant-free data transmission in a radio communication network. The proposed method includes composing, by a Base Station (BS), a Select Signal (SS) for a transceiver device, where the SS is configured to control a grant-free data transmission from the transceiver device. Further, the proposed method includes transmitting, by the BS, the SS to the transceiver device. Further, the proposed method includes receiving, by a transceiver device, the SS from the BS. Further, the proposed method includes decoding, by the transceiver device, the SS and furthermore, the proposed method includes controlling, by the transceiver device, a data transmission by one of activating the grant-free data transmission from the transceiver device in response to successful decoding of the SS, and deactivating the grant-free data transmission from the transceiver device in response to unsuccessful decoding of the SS.Type: GrantFiled: January 6, 2018Date of Patent: December 6, 2022Assignees: CENTRE OF EXCELLENCE IN WIRELESS TECHNOLOGY CEWIT, INDIAN INSTITUTE OF TECHNOLOGY MADRASInventors: Nithin Srinivasan, Dhivagar Baskaran, Chandrasekaran Mohandoss, Sunil Kaimalettu, Jeniston Deviraj Klutto Milleth, Bhaskar Ramamurthi
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Patent number: 11522200Abstract: The present disclosure is a method for manufacturing a catalyst for a fuel cell using the blood of slaughtered livestock. The method for manufacturing a catalyst for a fuel cell using the blood of slaughtered livestock of the present disclosure allows preparation of a catalyst for a fuel cell exhibiting high redox reaction activity and very superior durability as compared to a commercially available platinum catalyst through a very simple process of purification of the blood of slaughtered livestock and hydrothermal synthesis. In addition, the method is very economical in that a catalyst is prepared using the pure blood of livestock only without an artificial additive, waste disposal cost can be reduced by recycling the blood of livestock and a high-performance catalyst capable of replacing the expensive platinum catalyst can be prepared.Type: GrantFiled: December 11, 2019Date of Patent: December 6, 2022Assignee: Korea Institute of Science and TechnologyInventors: Sung Jong Yoo, Hee-Young Park, So Young Lee, Hyun Seo Park, Jin Young Kim, Jong Hyun Jang, Hyoung-Juhn Kim, Pil Kim, Yeonsun Sohn, Jiho Lee
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Patent number: 11518744Abstract: The present invention relates to a benzamide compound and a preparation method, use and pharmaceutical composition thereof. The benzamide compound represented by formula (I) is a STAT3 inhibitor, and can be used to prevent and/or treat a disease related to STAT3 activity, such as a tumor, autoimmune disease, renal disease, cardiovascular disease, inflammation, metabolic/endocrine dysfunction, and neurological disease.Type: GrantFiled: January 30, 2019Date of Patent: December 6, 2022Assignee: INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCESInventors: Heng Xu, Xiaoguang Chen, Songwen Lin, Ming Ji, Nina Xue, Deyu Wu, Jing Jin
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Patent number: 11522115Abstract: Conventional readout of a superconducting nanowire single-photon detector (SNSPD) sets an upper bound on the output voltage to be the product of the bias current and the load impedance, IB×Zload, where Zload is limited to 50? in standard RF electronics. This limit is broken/exceeded by interfacing the 50? load and the SNSPD using an integrated superconducting transmission line taper. The taper is a transformer that effectively loads the SNSPD with high impedance without latching. The taper increases the amplitude of the detector output while preserving the fast rising edge. Using a taper with a starting width of 500 nm, a 3.6× higher pulse amplitude, 3.7× faster slew rate, and 25.1 ps smaller timing jitter was observed. The taper also makes the detector's output voltage sensitive to the number of photon-induced hotspots and enables photon number resolution.Type: GrantFiled: March 4, 2020Date of Patent: December 6, 2022Assignees: Massachusetts Institute of Technology, California Institute of TechnologyInventors: Di Zhu, Marco Colangelo, Boris Korzh, Matthew Shaw, Karl K. Berggren