Abstract: Provided herein are methods for enhancing infection, growth, spread, or titer of an oncolytic RNA virus in a cancer or tumor cell; enhancing the oncolytic activity, cytokine-induced cell death activity, and/or cytotoxic activity of an oncolytic RNA virus in a cancer or tumor cell; upregulating cytokine response to, and/or enhancing the immunotherapeutic activity of an oncolytic RNA virus in a cancer or tumor cell; and/or treating a tumor or cancer in a subject in need thereof. Such methods employ a vanadium-containing compound, administered to the cancer or tumor cells before, after, or concurrently with infection of the cancer or tumor cells with the oncolytic RNA virus. Related compositions, uses, and kits therefor are also provided. Methods for producing RNA viruses, RNA virus-based cancer vaccines, and RNA virus-based cancer gene therapy vectors are also provided.

Abstract: One or more embodiments of the disclosure include systems and methods that use meta-learning to learn how to optimally find a new neural network architecture for a task using past architectures that were optimized for other tasks, including for example tasks associated with autonomous, semi-autonomous, assisted, or other driving applications. A computer implemented method of the disclosure includes configuring a search space lattice comprising nodes representing operator choices, edges, and a maximum depth. The method includes defining an objective function. The method further includes configuring a graph network over the search space lattice to predict edge weights over the search space lattice.

Abstract: A fiber spreading apparatus which is configured to spread a carbon fiber bundle, and includes a feeding roll, a winding roll, a vibrating roller, and a first nozzle. The vibrating roller is disposed between the feeding roll and the winding roll, and is in contact with the carbon fiber bundle. The vibrating roller is rotated according to an axis of rotation, and is vibrated along a vibrating direction perpendicular to the axis of rotation. The first nozzle is disposed between the vibrating roller and the winding roll, and blows the carbon fiber bundle.

Abstract: Network materials which exhibit both shear thinning and self-healing properties are disclosed. The networks contain particles and gel-forming compounds. The networks are useful for a variety of biomedical uses, including drug delivery.

Abstract: Methods and devices are described for performing an all-phase measurement of an ultra-fast laser pulse having a spectral range of greater than one octave. The ultra-fast laser pulse may be split into a first beam comprising a fundamental light with a wavelength ?0 and a second beam comprising a light with a wavelength 2?0. The light with the wavelength 2?0 may be frequency doubled to a light with a wavelength ?0 to generate an interference with the fundamental light. Fourier transform may be performed on an interference spectrum of the interference, and a relative envelope delay (RED) between the fundamental light and the frequency doubled light and a carrier envelope phase (CEP) may be acquired based on a result of the Fourier transform.

Abstract: Disclosed is a digital audio tampering forensics method based on phase offset detection, comprising: multiplying a signal to be identified with a time label to obtain a modulation signal of the signal to be identified; then, performing a short-time Fourier transform on the signal to be identified and the modulation signal to obtain a signal power spectrum and a modulation signal power spectrum; computing group delay characteristics by using the signal power spectrum and the modulation signal power spectrum; computing a mean value of the group delay characteristics, and then using the mean value results for smoothing computation to obtain phase information of a current frame signal; computing a dynamic threshold by using the phase information of the current frame signal, and then deciding whether the signal is tampered by using the dynamic threshold and the phase information of the current frame signal.

Abstract: This invention relates to methods comprising administering a FAK inhibitor (e.g., VS-6063) in combination with a dual RAF/MEK inhibitor (e.g., CHS 126766) that are useful in the treatment of abnormal cell growth, such as cancer, in a subject such as humans.

Abstract: The present application relates to compounds of Formula I or pharmaceutically acceptable salts, solvates and/or prodrugs thereof, to compositions comprising these compounds or pharmaceutically acceptable salts, solvates and/or prodrugs thereof, and various uses in the treatment of diseases, disorders or conditions that are treatable by inhibiting interactions with BCL6 BTB, such as cancer.

Abstract: An electrode for electroporation comprising a plurality of electrode needles, wherein first polarity electrode needles, an electrode needle holding portion, and a syringe holding portion are provided; two or more first polarity electrode needles project from a bottom surface of a lower structural body of an outer frame support of the electrode needle holding portion toward an electroporation target side; the bottom surface of the lower structural body of the outer frame support is provided with a hole for syringe needle insertion and removal communicating with a syringe holding portion side; the syringe holding portion is provided on a side opposite to the electroporation target side of the electrode needle holding portion; and the syringe holding portion has a path for syringe needle insertion and removal, at least a portion of the path for syringe needle insertion and removal being provided with an electro-conductive portion for a second polarity.

Abstract: Methods and systems for the electrochemical conversion of halogenated compounds are provided. In some embodiments, a method comprises converting a halogenated compound (e.g., fluorinated gas) to relatively non-hazardous products via one or more electrochemical reactions. The electrochemical reaction(s) may occur under relatively mild conditions (e.g., low temperature) and/or without the aid of a catalyst. In some embodiments, the electrochemical reaction may produce a relatively large amount of energy. In some such cases, systems, described herein, may be designed to facilitate the conversion of the halogenated compound (e.g., SF6, NF3) while harnessing (e.g., storing, converting) the energy associated with the electrochemical reaction. System and methods described herein may be used in a wide variety of applications, including waste management (e.g., environmental remediation, greenhouse gas mitigation), energy recovery (e.g., industrial energy recovery), and primary batteries (e.g., metal-gas batteries).

Abstract: Footwear scanning systems and associated methods are described. According to one aspect, a footwear scanning system includes a base, a shuttle configured to rotate beneath the base, wherein the shuttle comprises an antenna array configured to transmit electromagnetic waves through the base into footwear above the base during the rotation of the shuttle and to receive electromagnetic waves reflected from the footwear during the rotation of the shuttle, a transceiver coupled with the antenna array and configured to apply electrical signals to the antenna array to generate the transmitted electromagnetic waves and to receive electrical signals from the antenna array corresponding to the received electromagnetic waves, and processing circuitry configured to process an output of the transceiver corresponding to the received electromagnetic waves to provide information regarding contents within the footwear.

Abstract: Various embodiments of a two-stage on-board battery charger that can generate a wide range of output voltages is described herein. Generally, the battery charger employs a first stage buck and boost Power Factor Correction (PFC) converter, and a second stage DC-DC converter. The buck and boost PFC converter is capable of generating variable intermediate DC-link voltages which allow the on-board battery charger to efficiently generate the wider range of output voltages.

Abstract: The present disclosure relates to a method of sequencing nascent RNA in a cell. In some embodiments, the nascent RNA is conjugated to DNA using copper-catalyzed azide-alkyne cycloaddition (CuAAC). Methods of the present disclosure can be used to generate genomic libraries of a cell and measure gene expression and enhancer and/or super-enhancer activity.

Abstract: A NaY molecular sieve with an aluminum-rich surface is prepared using a process that includes the steps of: a. mixing a directing agent and a first silicon source to obtain a first mixture, wherein the directing agent has a molar composition of Na2O:Al2O3:SiO2:H2O=(6-25):1:(6-25):(200-400); b. mixing the first mixture obtained in the step a with a second silicon source, an aluminum source and water to obtain a second mixture; c. carrying out hydrothermal crystallization on the second mixture obtained in the step b, and collecting a solid product. Calculated as SiO2, the weight ratio of the first silicon source to the second silicon source is 1:(0.01-12). The NaY molecular sieve has larger aluminum distribution gradient from the surface to the center of the particle than the conventional molecular sieve.

Abstract: A shear assisted extrusion process for producing cladded materials wherein a cladding material and a material to be cladded are placed in sequence with the cladded material positioned to contact a rotating scroll face first and the material to be cladded second. The two materials are fed through a shear assisted extrusion device at a preselected feed rate and impacted by a rotating scroll face to generate a cladded extrusion product. This process allows for increased through wall strength and decreases the brittleness in formed structures as compared to the prior art.

Abstract: Process heaters and associated methods of processing with ultra-low pollutant emissions are provided. The process heaters and methods utilize a heat exchange tube having disposed therein a radiant permeable matrix burner at a first end of the tube. The tube further includes a thermally insulated insert disposed adjacent the radiant burner opposite an oxidant-fuel mixer that feeds the burner. The process heaters and methods act to reduce emissions of CO and NOx.

Abstract: A method and device for generating synthetic vortex sound field (SVSF) with more mode number includes the following steps: (1) a transducer array composed of N transducer units is constructed, and each transducer unit emits a sound field to generate an initial sound field; (2) at the same time, the position of the transducer unit and the phase of the sound field emitted by each transducer unit are changed, and each change produces a sound field, and thus changings times produces of sound fields, wherein the way to change the position of the transducer unit is to rotate the transducer array as a whole; (3) the initial sound field is superimposed with s of sound fields generated in step (2), to obtain SVSF with more mode number. The method and device for generating vortex sound field (VSF) can be used for underwater communication or acoustic imaging.

Abstract: Disclosed are a quantum information transmitter, a quantum communication system including the same, and an operating method of the quantum information transmitter. The quantum information transmitter includes a light source driver, a light source, and a light modulator. The light source driver generates a first light source driving signal having a first level and a second light source driving signal having a second level. The light source generates a first light signal having a first average number of photons in response to the first light source driving signal, and generates a second light signal having a second average number of photons in response to the second light source driving signal. The optical modulator modulates the first light signal to generate a target signal, and modulates the second light signal to generate a decoy signal.

Abstract: Devices and methods for performing dielectrophoresis are described. The devices contain sample channel which is separated by physical barriers from electrode channels which receive electrodes. The devices and methods may be used for the separation and analysis of particles in solution, including the separation and isolation of cells of a specific type. As the electrodes do not make contact with the sample, electrode fouling is avoided and sample integrity is better maintained.

Abstract: A wireless communication method and apparatus in a wireless local area network (WLAN) system are disclosed. A wireless communication method according to one embodiment may include generating a high-efficiency Wi-Fi (HEW) frame including at least one of an HEW-SIG-A field and an HEW-SIG-B field which include channel information for communications according to an Orthogonal Frequency-Division Multiple Access (OFDMA) mode, and transmitting the generated HEW frame to a reception apparatus.