Abstract: An apparatus and method to detect disease-specific antigens assists in disease diagnosis. Point-of-care (POC) micro biochip incorporates at least one hydrophilic microchannel for controlled and self-driven flow of body fluid. Metallic nano-interdigitated electrodes disposed within the channels give enhanced sensitivity detection. Microchannel controls flow and amplifies a capillary effect. Electrodes are fabricated on microchannel surface to detect biomolecular interactions. When a sample flows through microchannel, disease-specific antigens from the sample form antigen-antibody complex with antibodies immobilized on electrodes. Antigen-antibody interaction is detected via an electrical change in the biochip's nano circuit. Each electrode may include a different antibody to detect different antigens. Capacitance during antigen-antibody interaction without microfluidic flow is higher than with microfluidic flow due to immobilized antibodies instability on sensing surface caused by shear stress.

Abstract: Provided is a method of preparing composite nanoparticles, which includes: a) preparing a metal nanocore having a nano-star shape from a first reaction solution in which a first metal precursor is mixed with a first buffer solution; b) fixing a Raman reporter in the metal nanocore; and c) forming a metal shell, which surrounds the nanocore in which the Raman reporter is fixed, from a second reaction solution in which the nanocore in which the Raman reporter is fixed, and a second metal precursor are mixed with a second buffer solution.

Abstract: An image recognition device includes: an image processing device that acquires a feature amount from an image; and an identification device that determines whether a prescribed identification object is present in the image, and identifies the identification object. The identification device includes a BNN that has learned the identification object in advance, and performs identification processing by performing a binary calculation with the BNN on the feature amount acquired by the image processing device. Then, the identification device selects a portion effective for identification from among high-dimensional feature amounts output by the image processing device to reduce the dimensions used in identification processing, and copies low-dimensional feature amounts output by the image processing device to increase dimensions.

Abstract: A Static Random Access Memory (SRAM) cell that may include a first pull-up transistor, a second pull-up transistor, a first pull-down transistor, a second pull-down transistor, a first pass-gate transistor and a second pass-gate transistor provided at two levels on a substrate. The respective transistors may be vertical transistors. The first pull-up transistor and the second pull-up transistor may be provided at a first level, and the first pull-down transistor, the second pull-down transistor, the first pass-gate transistor and the second pass-gate transistor may be provided at a second level different from the first level. A region where the first pull-up transistor and the second pull-up transistor are located and a region where the first pull-down transistor, the second pull-down transistor, the first pass-gate transistor and the second pass-gate transistor are located may at least partially overlap in a vertical direction with respect to an upper surface of the substrate.

Abstract: A method of decoding an image with a decoding apparatus includes receiving a bitstream in which the image is encoded; and dividing a first coding block in the image into a plurality of second coding blocks. The tree structure-based block division includes a binary-tree division and a triple-tree division, and the binary-tree division is representative of a division type to divide one coding block into two coding blocks and the triple-tree division is representative of a division type to divide one coding block into three coding blocks. The method also includes decoding each of the second coding blocks with reference to syntax information acquired from the bitstream. The syntax information includes most probable mode (MPM) information.

Abstract: The subject matter of this invention relates to hydrogel compositions and, more particularly, to hydrogel compositions comprising block copolymers (BCPs) capable of self-assembly into nanoparticles for the delivery and controlled release of therapeutic cargos.

Abstract: A project generating method comprises extracting a keyword from a plurality of text files with a specified category, determining whether the keyword is a theme, extracting a geographical name from the text files corresponding to the theme, determining whether to keep the theme according to an internet volume of the theme, filtering a plurality of review files from a review website according to the geographical name, calculating a first ratio therein to determining whether to keep the theme, and generating a project including the geographical name and the theme serving as a recommendation row.

Abstract: A distributed deep learning network may prevent an attacker from reconstructing raw data from activation outputs of an intermediate layer of the network. To achieve this, the loss function of the network may tend to reduce distance correlation between raw data and the activation outputs. For instance, the loss function may be the sum of two terms, where the first term is weighted distance correlation between raw data and activation outputs of a split layer of the network, and the second term is weighted categorical cross entropy of actual labels and label predictions. Distance correlation with the entire raw data may be minimized. Alternatively, distance correlation with only with certain features of the raw data may be minimized, in order to ensure attribute-level privacy. In some cases, a client computer calculates decorrelated representations of raw data before sharing information about the data with external computers.

Abstract: The present invention relates to macrocyclic indole derivatives of general formula (I): in which R1, R2, R3, R4, R5, R6, A and L are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds, and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative disorders, as a sole agent or in combination with other active ingredients.

Abstract: The present disclosure provides an anti-fogging material and a manufacturing method thereof. The anti-fogging material includes a crosslinked polymer obtained by curing an anti-fogging composition, wherein the anti-fogging composition includes an ionic compound, a hard compound with two or more acrylate functional groups at the terminus thereof, and a surface active compound.

Abstract: An anode includes a mixed ionic-electronic conductor (MIEC) with an open pore structure. The open pore structure includes open pores to facilitate motion of an alkali metal into and/or out of the MIEC. The open pore structure thus provides open space to relieve the stresses generated by the alkali metal when charging/discharging a battery. The MIEC is formed from a material that is thermodynamically and electrochemically stable against the alkali metal to prevent the formation of solid-electrolyte interphase (SEI) debris and the formation of dead alkali metal. The MIEC may also be passive (the MIEC does not store or release alkali metal). In one example, the open pore structure may be an array of substantially aligned tubules with a width less than about 300 nm, a wall thickness between about 1 nm to about 30 nm, and a height of at least 10 um arranged as a honeycomb.

Abstract: An access method, a network device, and a mobile communication terminal are provided. The access method applied to the network device includes transmitting frequency information of a downlink frequency range and at least two uplink frequency ranges and a physical random access channel parameter.

Abstract: A C-shaped active area semiconductor device and a method of manufacturing the same and electronic device including the semiconductor device are provided. According to embodiments, the semiconductor device includes: a channel portion extending vertically on a substrate; source/drain portions located at upper and lower ends of the channel portion relative to the substrate and along the channel portion, wherein the source/drain portion extends toward a side of the channel portion in a lateral direction relative to the substrate, so that the source/drain portions and the channel portion constitute a C-shaped structure; and a gate stack that overlaps the channel portion on an inner sidewall of the C-shaped structure, wherein the gate stack has a portion surrounded by the C-shaped structure.

Abstract: A data storage system includes a host configured to provide a read request; a plurality of storage devices constituting a redundant array of independent disks (RAID); and a RAID controller configured to a plurality of read commands in response to the read request, the read commands being provided to the plurality of storage devices according to a RAID setting, wherein one data storage device of the plurality of data storage devices includes a nonvolatile memory device; an error handling information storage circuit to store error handling information; and an error detection and correction circuit configured to detect an error in data output from the nonvolatile memory device according to a read command and to selectively correct the error according to the error handling information.

Abstract: A method for separating a calcite-rich low-grade fluorite barite paragenic ore, includes the following steps: S1, crushing; S2, performing classification on a crushed ore to obtain a fine-grained ore, a medium-grained ore and a coarse-grained ore; S3, performing jigging gravity separation on the medium-grained ore and the coarse-grained ore to obtain first barite concentrates and jigging tailings; S4, performing color sorting on the jigging tailings to obtain calcite minerals and color sorting tailings; S5, combining the fine-grained ore and the color sorting tailings, and then performing ore grinding to obtain feeding materials in flotation; S6, performing flotation on the feeding materials in flotation to obtain fluorite concentrates and flotation tailings; S7, performing chute gravity separation on the flotation tailings to obtain second barite concentrates and chute tailings. The method achieves an effect of obtaining high-quality acid-grade fluorite concentrates (CaF2?98%).

Abstract: A rotational structure is configured such that a hollow portion, in which a base member is opposed to a rotational member, is formed around a shaft member. An encoder provided in the hollow portion includes a detection target member rotated together with one of the rotational member and the base member and having a physical quantity changing in a circumferential direction, and a detector capable of detecting the physical quantity of the detection target element and rotated together with the other of the rotational member and the base member.

Abstract: Disclosed herein is a nano-magnetic-particle-imaging apparatus, including a measurement head including excitation and detection coils and accommodating a sample bed for a sample including nano magnetic particles; a gradient magnetic field generation unit for generating a magnetic field having a strength equal to or greater than that of the saturation magnetic field of the nano magnetic particles in a spacing area between identical magnetic poles facing each other and forming a field-free region in a portion thereof; a first driving unit for linearly moving the sample bed; a second driving unit for rotating the gradient magnetic field generation unit in a plane; a third driving unit for linearly reciprocating the gradient magnetic field generation unit; and a control unit for applying a signal to the excitation coil, controlling the driving units, and imaging 3D distribution of the nano magnetic particles based on a detection signal output from the detection coil.

Abstract: Provided herein are methods and compositions related to the selection T cells and/or subjects for adoptive immunotherapy based on the expression of one or more biomarkers.

Abstract: Disclosed is a method of providing a sign language video reflecting an appearance of a conversation partner. The method includes recognizing a speech language sentence from speech information, and recognizing an appearance image and a background image from video information. The method further comprises acquiring multiple pieces of word-joint information corresponding to the speech language sentence from joint information database, sequentially inputting the word-joint information to a deep learning neural network to generate sentence-joint information, generating a motion model on the basis of the sentence-joint information, and generating a sign language video in which the background image and the appearance image are synthesized with the motion model. The method provides a natural communication environment between a sign language user and a speech language user.

Abstract: The invention provides amides that inhibit cellular necrosis and/or human receptor interacting protein 1 kinase (RIP1), including corresponding sulfonamides, and pharmaceutically acceptable salts, hydrates and stereoisomers thereof. The compounds are employed in pharmaceutical compositions, and methods of making and use, including treating a person in need thereof with an effective amount of the compound or composition, and detecting a resultant improvement in the person's health or condition.