Abstract: The present disclosure provides compounds of Formula (I) and Formula (II), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, and prodrugs thereof. The provided compounds may be kinase (e.g., Janus kinase (JAK) (e.g., Janus kinase 2 (JAK2)) and/or cyclin-dependent kinase (CDK) (e.g., cyclin-dependent kinase 11 (CDK11)) inhibitors. Also provided are pharmaceutical compositions and kits including the provided compounds. Further provided are methods of using the provided compounds, pharmaceutical compositions, and kits (e.g., for treating a disease (e.g., proliferative disease) in a subject in need thereof).

Abstract: A method for vehicle prediction, planning, and control is described. The method includes separately encoding traffic state information at an intersection into corresponding traffic state latent spaces. The method also includes aggregating the corresponding traffic state latent spaces to form a generalized traffic geometry latent space. The method further includes interpreting the generalized traffic geometry latent space to form a traffic flow map including current and future vehicle trajectories. The method also includes decoding the generalized traffic geometry latent space to predict a vehicle behavior according to the traffic flow map based on the current and future vehicle trajectories.

Abstract: Disclosed are methods and apparatuses for image data encoding/decoding. A method of decoding an image includes receiving a bitstream in which the image is encoded; obtaining index information for specifying a block division type of a current block in the image; and determining the block division type of the current block from a candidate group pre-defined in the decoding apparatus. The candidate group includes a plurality of candidate division types, including at least one of a non-division, a first quad-division, a second quad-division, a binary-division or a triple-division. The method also includes dividing the current block into a plurality of sub-blocks; and decoding each of the sub-blocks with reference to syntax information obtained from the bitstream.

Abstract: A catalyst for an oxygen reduction reaction containing catalyst particles having a shell-core structure containing a PtCo alloy or a PtCoMn alloy as a core, and platinum as a shell layer. A specific plane of a face-centered cubic lattice is formed by a plurality of platinum atoms contained in the shell layer, and a lattice constant of the plane of the face-centered cubic lattice on the catalyst particle surface is 3.70 ? or more and 4.05 ? or less (in a PtCo alloy), or 3.870 ? or more and 4.10 ? or less (in a PtCoMn alloy). A catalyst design method includes a step of calculating, with respect to an orientation plane such as the plane formed by platinum atoms of the shell layer, adsorption energies for an oxygen molecule, an OH group and a water molecule by first-principles calculation based on density functional theory.

Abstract: Proposed is a system and method for simulations of marine pollution dispersion using a numerical tracer technique, wherein modeling is faster than conventional diffusion modeling methods by reducing computational volume and load and thereby a simulation of marine pollution dispersion with respect to the long-term continuous discharge may be performed through the numerical tracer technique by configuring to simulate the marine dispersion of suspended sediments (SS) and COD using the Quick Dispersion (Q-DISP) model, which is a diffusion model using the Monte Carlo method, in order to solve the problems of conventional marine pollution dispersion modeling systems and methods using numerical tracer techniques which have the disadvantage of requiring a high-performance computer and a large amount of memory due to the increased computation.

Abstract: Systems and methods for altering the geometry of a fluid channel to prevent upstream mobility of bacteria, using angled obstacles on the interior of the channel that among other things creates vortices that restrict the mobility. An optimized geometry can be realized by an artificial intelligence algorithm or similar methods based on performance of various configurations of obstacle parameters.

Abstract: The disclosure relates to a micro component structure and a manufacturing method thereof, and a transfer method for a light-emitting diode (LED) chip. The micro component structure includes a substrate (300), multiple stacked adhesive layer structures spaced on a first surface (300a) of the substrate (300), and multiple LED chips (20) correspondingly disposed on the multiple stacked adhesive layer structures. Each of the multiple LED chips (20) has two extraction electrodes (21) at a surface facing toward the multiple stacked adhesive layer structures. Each of the multiple stacked adhesive layer structures includes a photolysis adhesive layer (31?) and a pyrolysis adhesive layer (32?) that are stacked. The photolysis adhesive layer (31?) is in contact with the first surface (300a). The pyrolysis adhesive layer (32?) is located between the two extraction electrodes (21) and has a thickness greater than a height of each of the two extraction electrodes (21).

Abstract: A method of predicting fabric features is disclosed herein, and the method includes following operations. Inputting first fabric information of a first fabric. Generating first fabric feature values of the first fabric. Performing a first calculation on the first fabric information and the first fabric feature values. Generating feature parameters and first predicted feature values of the first fabric by the first calculation. Inputting second fabric information of a second fabric. Generating second fabric feature values of the second fabric according to the second fabric information and the feature parameters. A system of predicting fabric features is also disclosed herein.

Abstract: A biosensor using an exceptional point is disclosed. A biosensor according to one embodiment of the present disclosure includes: a biosensing unit configured to output wavelength-separated optical signals from destruction of an exceptional point resulting from attachment of biomolecules; a detection unit configured to convert the wavelength-separated optical signals into wavelength-separated electrical signals; an analysis unit configured to measure a beat frequency resulting from the wavelength-separated electrical signals; and a determination unit configured to determine a wavelength difference resulting from the beat frequency, thereby determining the amount of the biomolecules therefrom.

Abstract: The invention relates to a process of converting methanol in a fluidized bed reactor comprising feeding a methanol-containing feedstock into a fluidized bed reactor, contacting the feedstock with a catalyst, to produce a product comprising ethylene and propylene under effective conditions; the fluidized bed reactor comprises a diluent-phase zone and a dense-phase zone, wherein the diluent-phase temperature difference between any regions of the diluent-phase zone having a methanol concentration of more than 0.1 wt % (preferably more than 0.01 wt %) in the fluidized bed reactor is controlled to be less than 20° C., and the dense-phase temperature difference between any regions in the dense-phase zone having a methanol concentration of more than 0.1 wt % (preferably more than 0.01 wt %) in the fluidized bed reactor is controlled to be less than 10° C.

Abstract: A system and method for measuring a hydration level in human tissue. The system includes a coaxial probe have a first end configured to be in contract with human tissue and configured to be emit and receive signals associated with a spectroscopic technique and having a second end adapted to be coupled to transmit and receive circuitry. The system further includes a patch or other means coupled to the coaxial probe and configured to be adhered to human tissue so as to provide a force upon at least a portion of the coaxial probe configured to be in contact with human tissue. In embodiments, the system may further include means coupled to receive signals from the coaxial probe, for determining an amount of liquid within a portion of human tissue in contact with the first end of the probe.

Abstract: Provided is a transmissive display apparatus capable of naturally combining a projection image on a real space scene. A beam splitter splits a light incident from a real space scene into first and second portions. An image sensor generates a real space image according to the second portion of the incident light. A light modulator passes at least a part of the first portion of the incident light according to a masking image. A control and projection image generation unit selects a target object and generates the masking image based on a target object area to cause a light modulator to block a foreground of the real space scene and pass a background of the real space scene. A projection unit generates a projection image light corresponding to the projection image combines the projection image light with a part of the first portion of the incident light.

Abstract: A cluster-supporting catalyst including porous carrier particles having acid sites, and catalyst metal clusters supported within the pores of the porous carrier particles. The catalyst metal clusters are obtained by supporting catalyst metal clusters having a positive charge, which is formed in a dispersion liquid containing a dispersion medium and the porous carrier particles dispersed in the dispersion medium, on the acid sites within the pores of the porous carrier particles through an electrostatic interaction.

Abstract: A multi-phase electrolyte film includes a first phase comprising a metal oxide, wherein the metal oxide is amorphous, crystalline, or a glass; and a second phase comprising a lithium salt having a decomposition temperature in air of greater than 200° C. or a lithium halide. The first phase is dispersed in the second phase and has an average particle size of 5 to 200 nanometers. Methods for the manufacture of the electrolyte film are also disclosed.

Abstract: Embodiments of the present disclosure provide a method for lane changing decision for vehicles on expressways considering safety risks in a networked environment, which is applicable to a multi-lane expressway. The method includes collecting a demand for lane change of a target vehicle; collecting a roadway and a lane where the target vehicle is located; collecting intervals between the target vehicle and a front vehicle and a rear vehicle on a lane that is switching into; determining a lane change direction of the vehicle; and executing a lane change operation by the target vehicle. A lane changing decision model provided in the embodiments of the present disclosure helps to improve the efficiency of lane change and the safety of lane change in expressways and provides a support for changing lanes in a multi-lane expressway.

Abstract: The present disclosure discloses a thermal management system. The thermal management system includes a refrigerant system and a coolant system. The thermal management system also includes a fourth heat exchanger. The fourth heat exchanger is disposed in the coolant system. The fourth heat exchanger can absorb heat from the air and release heat to the air, which is beneficial to improve the performance of the thermal management system.

Abstract: A downhole blowout preventer has a blowout preventer tubing string containing a circulation unit, a packer unit and a pressure-building unit connected in sequence from top to bottom. The pressure-building unit is configured to be activated in response to a command, so as to build up pressure in a space inside the blowout preventer tubing string. The packer unit is configured to be activated when a pressure in said space reaches a first predetermined value, so as to seal an annulus between said blowout preventer tubing string and an external casing or borehole. The circulation unit is configured to be activated when the pressure in said space reaches a second predetermined value, thereby creating a circulation path between an interior and an exterior of the blowout preventer tubing string. The first predetermined value is less than the second predetermined value.

Abstract: By providing propellers for vertical ascent and descent and for horizontal flight, and a blade for horizontal flight, it is possible to obtain an aerial vehicle capable of high-speed horizontal flight and capable of flying a long distance.

Abstract: An embodiment of the present invention provides a single-particle dispensing device, including: a first syringe containing particles and fluid therein; a particle separating body connected to an outlet end of the first syringe and separating the particles from the fluid; and a container connected to the particle separating body and containing the fluid separated in the particle separating body, wherein the particle separating body includes a rotating body provided with a particle collector collecting the particle and a fluid flow path formed therein, and a fixing body provided with a nozzle discharging the particle and rotatably accommodating the rotating body therein.

Abstract: Disclosed is a method and apparatus for measuring magnetic field and/or temperature using a diamond nitrogen-vacancy center sensor, and a measuring apparatus based on a diamond nitrogen-vacancy center (DNV) sensor may include: a diamond nitrogen-vacancy center sensor; a frequency synthesizer for generating a first reference signal and a second reference signal; a first microwave generator for generating a first microwave that is frequency modulated according to the first reference signal and causes a first spin transition in the diamond nitrogen-vacancy center sensor; a second microwave generator for generating a second microwave that is frequency modulated according to the second reference signal and causes a second spin transition in the diamond nitrogen-vacancy center sensor; a laser irradiator for applying a laser to excite the spin state of the diamond nitrogen-vacancy center sensor; a power amplifier for combining and amplifying the first microwave and the second microwave to apply to the diamond nitrog