Patents Assigned to Japan Advanced Institute of Science and Technology
  • Patent number: 11812739
    Abstract: Provided are a vitrification stabilizer for an animal cell cryopreservation fluid, and an animal cell cryopreservation fluid which exhibits superior vitrification capabilities due to the animal cell cryopreservation fluid containing the vitrification stabilizer for an animal cell cryopreservation fluid. The vitrification stabilizer for an animal cell cryopreservation fluid contains: an amphoteric polymer compound selected from the group consisting of (a) a carboxylated amphoteric polymer compound obtained by reacting ?-poly-L-lysine with butyl succinic anhydride, (b) a carboxylated amphoteric polymer compound obtained by reacting ?-poly-L-lysine with butyl succinic anhydride and succinic anhydride, or (c) a carboxylated amphoteric polymer compound obtained by reacting ?-poly-L-lysine with a compound represented by formula I; and (d) a sucrose polymer macromolecule to which epichlorohydrin has been crosslinked.
    Type: Grant
    Filed: February 15, 2017
    Date of Patent: November 14, 2023
    Assignee: JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Kazuaki Matsumura, Toshiaki Naka
  • Publication number: 20230277604
    Abstract: It is an object of the present invention to provide a therapeutic agent or a diagnostic agent for cancer, which has high selectivity to cancer and also has low toxicity or little side effects. According to the present invention, provided is a therapeutic agent or a diagnostic agent for cancer, comprising photosynthetic bacteria.
    Type: Application
    Filed: July 27, 2021
    Publication date: September 7, 2023
    Applicant: JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventor: Eijiro MIYAKO
  • Publication number: 20230212178
    Abstract: In the present invention, a method for producing a compound of formula I comprises a step for causing a compound of formula III to undergo a Pechmann condensation reaction with respect to a compound of formula II in the presence of an organic solvent and an acid catalyst to obtain a compound of formula IV, and due to such method, provided are a novel photoreactive compound and a method for producing same that can be used for nucleic acid photoreaction technology.
    Type: Application
    Filed: January 27, 2020
    Publication date: July 6, 2023
    Applicant: JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventor: Kenzo FUJIMOTO
  • Publication number: 20220411853
    Abstract: This transistor sensor includes a substrate, a channel layer provided over one surface of the substrate, and a solid electrolyte layer provided between the substrate and the channel layer or over a surface of the channel layer on an opposite side to the substrate side, in which the channel layer includes an inorganic semiconductor, the solid electrolyte layer includes an inorganic solid electrolyte, and at least a portion of either one or both of the channel layer and the solid electrolyte layer includes an exposed portion exposed to outside.
    Type: Application
    Filed: December 18, 2020
    Publication date: December 29, 2022
    Applicants: MITSUBISHI MATERIALS CORPORATION, JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Hiromi Nakazawa, Nobuyuki Soyama, Keiji Shirata, Toshihiro Doi, Tue Trong Phan, Yuzuru Takamura, Tatsuya Shimoda, Daisuke Hirose
  • Patent number: 11530286
    Abstract: The present invention provides a protein aggregation inhibitor for use in preventing aggregation of a protein, containing a crosslinked polymer obtained by polymerizing polymerizable polymer components containing a sulfobetaine polymer obtained by polymerizing monomer components containing a sulfobetaine monomer, the sulfobetaine monomer, and a crosslinkable monomer.
    Type: Grant
    Filed: May 30, 2017
    Date of Patent: December 20, 2022
    Assignees: OSAKA ORGANIC CHEMICAL INDUSTRY LTD., JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Kazuaki Matsumura, Rajan Robin, Yoko Taniyama, Yoshiyuki Saruwatari
  • Patent number: 11502235
    Abstract: A thermoelectric material includes a parent phase in which an MgSiSn alloy is a main component, a void formed in the parent phase, and a silicon layer that is formed on at least a wall surface of the void and that includes silicon as a main component. The thermoelectric material further includes MgO in an amount of 1.0 wt. % or more and 20.0 wt. % or less. The silicon layer includes amorphous Si, or amorphous Si and nanosized Si crystals, and the parent phase includes a region in which the composition ratio of the Si of the chemical composition of the MgSiSn alloy is higher than in the other regions and a region in which the composition ratio of the Sn of the chemical composition of the MgSiSn alloy is higher than in the other regions. With these configurations, the thermoelectric material realizes both lower thermal conductivity and lower electrical resistivity.
    Type: Grant
    Filed: August 10, 2018
    Date of Patent: November 15, 2022
    Assignees: HAKUSAN, INC., JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY, ISHIKAWA PREFECTURE
    Inventors: Shigeyuki Tsurumi, Kazumasa Yasuda, Takeshi Sotome, Mikio Koyano, Takeshi Toyoda, Akinari Matoba, Toshiharu Minamikawa
  • Patent number: 11214590
    Abstract: Provided are a compound represented by formula I that can be used in nucleic acid photoreaction techniques, and a photoreactive crosslinking agent comprising the compound.
    Type: Grant
    Filed: July 25, 2018
    Date of Patent: January 4, 2022
    Assignees: JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY, NICCA CHEMICAL CO., LTD.
    Inventors: Kenzo Fujimoto, Shigetaka Nakamura
  • Patent number: 11197473
    Abstract: Provided are a vitrification stabilizer for animal cell cryopreservation fluid, and an animal cell cryopreservation fluid that exhibits superior vitrification capacity due to containing said vitrification stabilizer for animal cell cryopreservation fluid. The vitrification stabilizer for animal cell cryopreservation fluid contains an amphoteric polymer compound selected from the group consisting of: (a) an amphoteric polymer compound obtained by reacting ?-poly-L-lysine with butyl succinic acid anhydride and performing carboxylation; (b) an amphoteric polymer compound obtained by reacting ?-poly-L-lysine with butyl succinic acid anhydride and succinic acid anhydride, and performing carboxylation; and (c) an amphoteric polymer compound obtained by reacting ?-poly-L-lysine with a compound represented by formula (I) and performing carboxylation.
    Type: Grant
    Filed: July 19, 2016
    Date of Patent: December 14, 2021
    Assignee: JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Kazuaki Matsumura, Manato Suzuki
  • Publication number: 20210322944
    Abstract: A hydrogel of which the degradation is accurately controlled can be provided by a photodegradable hydrogel production method, the method comprising the steps of: reacting ?-glucan having a weight average molecular weight of 2000 to 200,000 with a compound represented by formula I to introduce a group represented by formula II into the ?-glucan; oxidizing the ?-glucan having, introduced therein, the group represented by formula II with periodic acid or a periodate salt to introduce an aldehyde group into the ?-glucan; and adding aminated carrageenan gel beads having polydopamine particles embedded therein to a gelling agent which has been prepared by introducing a group represented by formula II and an aldehyde group into ?-glucan, and then causing the crosslinking reaction of the resultant product with a polythiol-type reducing agent to form the hydrogel.
    Type: Application
    Filed: July 19, 2019
    Publication date: October 21, 2021
    Applicant: JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Kazuaki MATSUMURA, Punnida NONSUWAN
  • Patent number: 11133191
    Abstract: The etching mask 80 for screen printing according to one embodiment of the present invention includes aliphatic polycarbonate. Further, the method of producing an oxide layer (the channel 44) according to one embodiment of the present invention includes: an etching-mask forming step of forming a pattern of the etching mask 80 including aliphatic polycarbonate; a contact step of, after the etching-mask forming step, contacting the oxide layer with a solution for dissolving a portion of the oxide layer (the channel 44) which is not protected by the etching mask 80; and a heating step of, after the contact step, heating the oxide layer (the channel 44) and the etching mask 80 to or above a temperature at which the etching mask 80 is decomposed.
    Type: Grant
    Filed: September 27, 2019
    Date of Patent: September 28, 2021
    Assignees: JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY, SUMITOMO SEIKA CHEMICALS CO., LTD.
    Inventors: Satoshi Inoue, Tatsuya Shimoda, Kazuhiro Fukada, Kiyoshi Nishioka, Nobutaka Fujimoto, Masahiro Suzuki
  • Patent number: 11078211
    Abstract: Provided are a compound represented by the following formula I; a novel photoreactive compound that can be used in nucleic acid photoreaction techniques by a photoreactive crosslinking agent comprising the compound; and a photoreactive crosslinking agent in which the photoreactive compound is used.
    Type: Grant
    Filed: July 19, 2018
    Date of Patent: August 3, 2021
    Assignees: JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY, NICCA CHEMICAL CO., LTD.
    Inventors: Takahiro Inatsugi, Ayako Koto, Isao Ishimaru, Masahiko Takamura, Kenzo Fujimoto
  • Patent number: 10995160
    Abstract: The present invention provides a protein aggregation inhibitor for use in preventing aggregation of a protein, which contains a terminal sulfanyl group-containing sulfobetaine polymer having a repeat unit derived from a sulfobetaine monomer represented by the formula (II), and a noble metal particle, and in which the terminal sulfanyl group-containing sulfobetaine polymer is chemisorbed on the noble metal particle by the sulfanyl group (the groups in the following formula are as defined in the DESCRIPTION).
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: May 4, 2021
    Assignees: OSAKA ORGANIC CHEMICAL INDUSTRY LTD., JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Kazuaki Matsumura, Rajan Robin, Yoko Taniyama, Yoshiyuki Saruwatari
  • Publication number: 20210084891
    Abstract: Provided are a vitrification stabilizer for an animal cell cryopreservation fluid, and an animal cell cryopreservation fluid which exhibits superior vitrification capabilities due to the animal cell cryopreservation fluid containing the vitrification stabilizer for an animal cell cryopreservation fluid. The vitrification stabilizer for an animal cell cryopreservation fluid contains: an amphoteric polymer compound selected from the group consisting of (a) a carboxylated amphoteric polymer compound obtained by reacting ?-poly-L-lysine with butyl succinic anhydride, (b) a carboxylated amphoteric polymer compound obtained by reacting ?-poly-L-lysine with butyl succinic anhydride and succinic anhydride, or (c) a carboxylated amphoteric polymer compound obtained by reacting ?-poly-L-lysine with a compound represented by formula I; and (d) a sucrose polymer macromolecule to which epichlorohydrin has been crosslinked.
    Type: Application
    Filed: February 15, 2017
    Publication date: March 25, 2021
    Applicant: JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Kazuaki Matsumura, Toshiaki Naka
  • Publication number: 20200332044
    Abstract: The present invention provides a protein aggregation inhibitor for use in preventing aggregation of a protein, containing a crosslinked polymer obtained by polymerizing polymerizable polymer components containing a sulfobetaine polymer obtained by polymerizing monomer components containing a sulfobetaine monomer, the sulfobetaine monomer, and a crosslinkable monomer.
    Type: Application
    Filed: May 30, 2017
    Publication date: October 22, 2020
    Applicants: OSAKA ORGANIC CHEMICAL INDUSTRY LTD., JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Kazuaki MATSUMURA, Rajan ROBIN, Yoko TANIYAMA, Yoshiyuki SARUWATARI
  • Publication number: 20200317685
    Abstract: Provided are a compound represented by the following formula I; a novel photoreactive compound that can be used in nucleic acid photoreaction techniques by a photoreactive crosslinking agent comprising the compound; and a photoreactive crosslinking agent in which the photoreactive compound is used.
    Type: Application
    Filed: July 19, 2018
    Publication date: October 8, 2020
    Applicants: JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY, NICCA CHEMICAL CO., LTD.
    Inventors: Takahiro Inatsugi, Ayako Koto, Isao Ishimaru, Masahiko Takamura, Kenzo Fujimoto
  • Patent number: 10784120
    Abstract: A laminate by using a paste or solution containing aliphatic polycarbonates having an etching mask function is provided. A method of producing a laminate of the present invention includes a pattern forming step of forming a pattern 80 of a first oxide precursor layer in which a compound of metal to be oxidized into a metal oxide is dispersed in a solution containing a binder (possibly including inevitable impurities) made of aliphatic polycarbonates on an oxide layer 44 or on the second oxide precursor layer to be oxidized into the oxide layer 44; an etching step of, after the pattern forming step, etching the oxide layer 44 or the second oxide precursor layer that is not protected by the pattern 80; and a heating step of, after the etching step, heating the oxide layer 44 or the second oxide precursor layer, and the first oxide precursor layer to a temperature at which the binder is decomposed or higher.
    Type: Grant
    Filed: November 21, 2016
    Date of Patent: September 22, 2020
    Assignees: JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY, SUMITOMO SEIKA CHEMICALS CO., LTD.
    Inventors: Satoshi Inoue, Tatsuya Shimoda, Kazuhiro Fukada, Kiyoshi Nishioka
  • Patent number: 10749034
    Abstract: It is an object of the invention to provide a thin film transistor and a method for producing the same, which will easily achieve self-aligned formation of a source/drain region without through processes under a vacuum or a low pressure or with no use of expensive equipment.
    Type: Grant
    Filed: April 25, 2018
    Date of Patent: August 18, 2020
    Assignees: Japan Advanced Institute of Science and Technology, Sumitomo Seika Chemicals Co., Ltd.
    Inventors: Satoshi Inoue, Tatsuya Shimoda, Nobutaka Fujimoto, Kiyoshi Nishioka, Shuichi Karashima
  • Publication number: 20200172563
    Abstract: Provided are a compound represented by formula I that can be used in nucleic acid photoreaction techniques, and a photoreactive crosslinking agent comprising the compound.
    Type: Application
    Filed: July 25, 2018
    Publication date: June 4, 2020
    Applicant: JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Kenzo Fujimoto, Shigetaka Nakamura
  • Patent number: 10634996
    Abstract: [Problem] Provided is a composite member which can contribute to simple formation and/or increased quality of fine wiring. [Solution] A composite member 100 according to one embodiment of the present invention includes a base material, an aliphatic polycarbonate-containing layer with multiple island-shaped portions arranged on the base material, and a metal ink, wherein at least a surface of the aliphatic polycarbonate-containing layer with multiple island-shaped portions has a contact angle of 50° or more between pure water and the surface when exposed to ultraviolet light including a wavelength of 180 nm or more and 370 nm or less for 15 minutes, and the metal ink is arranged on the base material at at least a portion of a region sandwiched by the precursor layers.
    Type: Grant
    Filed: July 21, 2016
    Date of Patent: April 28, 2020
    Assignees: JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY, SUMITOMO SEIKA CHEMICALS CO., LTD.
    Inventors: Satoshi Inoue, Tatsuya Shimoda, Kazuhiro Fukada, Kiyoshi Nishioka, Masahiro Suzuki
  • Patent number: 10475580
    Abstract: There are provided an oxide dielectric having excellent properties and a solid state electronic device (e.g., a capacitor, a semiconductor device, or a small electromechanical system) having such an oxide dielectric. An oxide layer 30 includes an oxide dielectric (possibly including inevitable impurities) including bismuth (Bi) and niobium (Nb) and having a first crystal phase of a pyrochlore-type crystal structure and a second crystal phase of a ?-BiNbO4-type crystal structure. The oxide layer 30 has a controlled content of the first crystal phase and a controlled content of the second crystal phase, in which the first crystal phase has a dielectric constant that decreases with increasing temperature of the oxide layer 30 in a temperature range of 25° C. or more and 120° C. or less, and the second crystal phase has a dielectric constant that increases with increasing temperature of the oxide layer 30 in the temperature range.
    Type: Grant
    Filed: July 10, 2015
    Date of Patent: November 12, 2019
    Assignees: JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY, ADAMANT NAMIKI PRECISION JEWEL CO., LTD.
    Inventors: Tatsuya Shimoda, Satoshi Inoue, Tomoki Ariga