Abstract: The organic EL device of the present invention includes an anode, a cathode (e.g., an Al layer (15)), and an organic layer 20 that is disposed between the anode and the cathode and that includes a light emitting layer 14. At least one side of the anode nearer to the organic layer (20) is formed of a transparent oxide semiconductor layer (e.g., an ITO layer (12)). The molybdenum oxide layer is disposed between the oxide semiconductor layer and the organic layer (20). The thickness of the molybdenum oxide layer is less than 2 nm when the molybdenum oxide layer is assumed to have a uniform thickness.

Abstract: A vortex extraction apparatus includes: a first numerical data calculation section calculating, for each vertex of each of voxels into which the inside of a fluid space is split, first numerical data indicating whether the vertex is located inside or outside a vortex region in a fluid; and a text data creation section determining the size of the vortex region around a center line of the vortex based on the first numerical data, and creating text data indicating the center line and the size. The apparatus further includes a polygon count reduction processing section counting the number of polygons defining a surface of the vortex region and each including an isosurface of the first numerical data, and integrating the voxels with new voxels into which the fluid space is roughly split until the number of polygons is not more than a set value, to decimate the first numerical data.

Abstract: The present invention provides a photoreactive crosslinking agent that is capable of crosslinking a sequence which cannot be photo-crosslinked by psoralen, and is capable of photo-crosslinking using a light having a longer wavelength, as compared with psoralen. The present invention also provides a compound having a group represented by formula (I) coupled with a group represented by formula (II).

Abstract: This invention provides a method for concentrating and collecting small quantities of fetal nucleated red blood cells contained in the maternal blood. The method for concentrating and collecting nucleated red blood cells from the maternal blood comprises: (i) subjecting the maternal blood to a first density-gradient centrifugation and collecting a cell fraction containing nucleated red blood cells; (ii) treating the cell fraction containing nucleated red blood cells so as to selectively changes the density of the nucleated red blood cells from that of the white blood cells; and (iii) subjecting the treated cell fraction containing the nucleated red blood cells to a second density-gradient centrifugation so as to collect a fraction containing nucleated red blood cells.

Abstract: Provided is a chip or the like having a particulate concentrating mechanism such as a mechanism that can selectively concentrate nucleated red blood cells contained in maternal blood and derived from a fetus and can collect the concentrated liquid rich in nucleated red blood cells, and also provided is a nucleated red blood cell concentrating/collecting method. A micro-channel chip for concentrating nucleated red blood cells has an inlet-side channel, an outlet-side channel, and a separation narrow channel provided between the inlet-side channel and the outlet-side channel. The separation narrow channel has an inner wall having a dimension through which non-nucleated red blood cells easily pass and nucleated red blood cells hardly pass, and has a means for deforming or moving part of the inner wall of the channel to have a dimension through which nucleated red blood cells easily pass.

Abstract: [PROBLEMS] To reduce the amount of, for example, a capturing antibody to be employed without lowering detection sensitivity. At the same time, to enable the achievement of intense color development or light emission in a determination area even in the case where only a small amount of a labeled antibody is accumulated. To lower the detection limit in the sandwich method. To enlarge the dynamic range in the competition method. [MEANS FOR SOLVING PROBLEMS] A method of analyzing a test substance by an immunological analysis method by using the test substance, a support having a determination area, on which one member selected from a capturing antibody capable of binding specifically to the test substance and a capturing antigen capable of binding specifically to the test substance has been immobilized, and a labeled antibody capable of binding specifically to the test substance, wherein a label having a sensitizing effect has been immobilized on the determination area of the support.

Abstract: A speech processing apparatus includes a spectrum envelope extracting unit which extracts the spectrum envelope of an input speech signal, a spectrum envelope deforming unit which applies deformation to the spectrum envelope to generate a deformed spectrum envelope, a spectrum fine structure extracting unit which extracts the spectrum fine structure of the input speech signal, a deformed spectrum generating unit which generates a deformed spectrum by combining the deformed spectrum envelope with the spectrum fine structure, and a speech generating unit which generates an output speech signal on the basis of the deformed spectrum. This apparatus emits a disrupting sound based on the output speech signal to prevent a third party from eavesdropping on a conversation.

Abstract: A method for evaluating the quality of a blood sample, comprising the steps of: mixing labeled anti-cortisol antibodies with a blood sample to be subjected, to conduct the antigen-antibody reaction of the labeled anti-cortisol antibody with cortisol contained in the blood sample, developing a mixture obtained in the above step on an immunochromatographic test strip having a substrate on which cortisol is immobilized to cause the antigen-antibody reaction of the labeled anti-cortisol antibodies which are free in the mixture with the cortisol immobilized on the substrate, thereby bonding the antibody to the cortisol, determining the amount of the labeled anti-cortisol antibodies bonded to the cortisol in the above step, and evaluating whether or not the blood sample has a quality suitable for suprarenal vein sampling test on the basis of the amount of the labeled anti-cortisol antibodies determined in the above step.

Abstract: An object of the present invention is to provide an effective method for measuring by NMR in real time, an NMR-detecting cell for measurement of NMR, and an NMR-measuring apparatus, and specifically, there has been found out a method for measuring NMR wherein a measurement sample is immobilized in a medium in an NMR-detecting cell that is an NMR detection part within an NMR-measuring magnet, and then measured by solution NMR in real time under the condition that the external environment around the immobilized measurement sample is consecutively changing.

Abstract: A cantilever heating mechanism, and a cantilever holder and cantilever heating method that use the same, which make high-efficiency heating possible in air or in a high or low vacuum even for a general cantilever where no heating wiring pattern is provided, and further that enable localized heating and localized high-pressure/high-temperature treatment of specimens. Provided are a holder (1), which can detachably hold a cantilever (L) with a probe tip, and at least a first electrode (2a) and a second electrode (2b), which are in electric contact with the cantilever (L) held by the holder (1). The holder (1) is equipped with a stationary base (11) and a fixing part (12), which fulfills the function of an electrode.

Abstract: Disclosed is a method for the purification and collection of a nucleic acid comprising a specific nucleotide sequence, which can be carried out within an extremely short period and can achieve both high sequence-specificity and a high collection rate. Specifically disclosed is a method for the purification of a target nucleic acid comprising a specific nucleotide sequence and contained in a nucleic acid mixture. The method comprises the steps of: hybridizing a photo-ligating nucleic acid having a group represented by formula (I) as abase moiety with the target nucleic acid to form a hybrid; irradiating the hybrid of the photo-ligating nucleic acid and the target nucleic acid with light to cause the photo-ligation of the hybrid; removing any un-photo-ligated nucleic acid by washing; and irradiating the hybrid of the photo-ligating nucleic acid and the target nucleic acid with light to cause the photo-cleavage of the hybrid.

Abstract: The present invention provides a method for detecting methylcytosine in DNA rapidly, conveniently, and with high sensitivity. The present invention relates to a method for detecting methylcytosine by using a methylcytosine photocoupling agent (a photoresponsive probe) consisting of nucleic acids having a group represented by the Formula (I), (II), (III) or (IV) as a base moiety.

Abstract: Disclosed is a method for the purification and collection of a nucleic acid comprising a specific nucleotide sequence, which can be carried out within an extremely short period and can achieve both high sequence-specificity and a high collection rate. Specifically disclosed is a method for the purification of a target nucleic acid comprising a specific nucleotide sequence and contained in a nucleic acid mixture. The method comprises the steps of: hybridizing a photo-ligating nucleic acid having a group represented by formula (I) as abase moiety with the target nucleic acid to form a hybrid; irradiating the hybrid of the photo-ligating nucleic acid and the target nucleic acid with light to cause the photo-ligation of the hybrid; removing any un-photo-ligated nucleic acid by washing; and irradiating the hybrid of the photo-ligating nucleic acid and the target nucleic acid with light to cause the photo-cleavage of the hybrid.

Abstract: A method for generating plasma and a method for elemental analysis, each comprising the steps of providing a narrow portion in a flow channel made of an insulation material, the narrow portion having a cross-sectional area markedly smaller than a cross-sectional area of the flow channel; filling the flow channel and the narrow portion with a conductive liquid, and thereafter applying an electric field to the narrow portion, to conduct the electric field through the narrow portion, thereby generating plasma at the narrow portion.

Abstract: A cell-sheet releasing agent of the present invention contains an aminated polyrotaxane. The polyrotaxane constituting the skeleton of the cell-releasing agent of the present invention has a structure in which cavities of a plurality of cyclic molecules are threaded onto a linear molecule and both terminals of the linear molecule have a bulky cap bonded thereto so that the cyclic molecules are not dethreaded from the linear molecule. Furthermore, the aminated polyrotaxane contained in the cell-releasing agent of the present invention is a compound in which at least some of hydroxy groups in the cyclodextrin structure contained in the polyrotaxane are each substituted with a substituent having an amino group. According to this cell-sheet releasing agent, cultured cells anchored to the surface of a container can be released without damaging the cells and without controlling the temperature.

Abstract: The present invention provides a photoreactive crosslinking agent that is capable of crosslinking a sequence which cannot be photo-crosslinked by psoralen, and is capable of photo-crosslinking using a light having a longer wavelength, as compared with psoralen. The present invention also provides a compound having a group represented by formula (I) coupled with a group represented by formula (II).

Abstract: The organic EL device of the present invention includes an anode, a cathode (e.g., an Al layer (15)), and an organic layer 20 that is disposed between the anode and the cathode and that includes a light emitting layer 14. At least one side of the anode nearer to the organic layer (20) is formed of a transparent oxide semiconductor layer (e.g., an ITO layer (12)). The molybdenum oxide layer is disposed between the oxide semiconductor layer and the organic layer (20). The thickness of the molybdenum oxide layer is less than 2 nm when the molybdenum oxide layer is assumed to have a uniform thickness.

Abstract: An object of the present invention is to provide an effective method for measuring by NMR in real time, an NMR-detecting cell for measurement of NMR, and an NMR-measuring apparatus. Specifically, there has been found out a method for measuring NMR wherein a measurement sample is immobilized in a medium in an NMR-detecting cell that is an NMR detection part within an NMR-measuring magnet, and then measured by solution NMR in real time under the condition that the external environment around the immobilized measurement sample is consecutively changing. This finding completes the present invention.

Abstract: An end point detection method in the case where a catalyst arranged in a treatment chamber of a gas phase reaction processing apparatus is heated at high temperature by supplying electric power thereto and the treatment is carried out by cracking a reaction gas by the catalyst heated at high temperature, comprises the steps of supplying the electric power to the catalyst from a constant current source, detecting electric potential difference between both ends of the catalyst, performing primary differentiation of the detected electric potential difference, and determining an end point of the treatment based on obtained primary differential value.

Abstract: A hard foam formed from a carboxylic acid ester-based polymer having a ring structure, the hard foam being obtained by heating the carboxylic acid ester-based polymer having a ring structure to generate a gaseous organic acid from the carboxylic acid ester-based polymer, and foaming the heated carboxylic acid ester-based polymer with the gaseous organic acid, and a method for producing the same. The hard foam can be used as various heat insulating materials, various vibration isolators, various acoustic materials, various soundproof materials and the like. Therefore, the hard foam is expected to be used for automobile component materials, materials for airplanes, materials for the space field, materials for industries, materials for medical assistance, and the like.