Patents Assigned to Johnson & Johnson
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Patent number: 12364679Abstract: The present invention relates to ophthalmic compositions and methods for the treatment of dry eye and other inflammatory ocular conditions. In particular, the present invention relates to a composition comprising an esterified anti-inflammatory lipid mediator, which is an ester of an anti-inflammatory lipid mediator that is a reaction product of the anti-inflammatory lipid mediator and a monohydric alcohol or an amide wherein the majority of the anti-inflammatory lipid mediator is present in an ester form. In this way, the compositions are substantially free of an acid form of the anti-inflammatory lipid mediators. Anti-inflammatory lipid mediators can be selected from the group consisting of polyunsaturated fatty acids (e.g.Type: GrantFiled: August 20, 2021Date of Patent: July 22, 2025Assignee: Johnson & Johnson Vision Care, Inc.Inventors: Annabelle Gallois-Bernos, Frank F. Molock, Jr., Carrie L. Davis, Kathrine Osborn Lorenz, James K. Young, Kristy L. Canavan, Fang Lu
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Patent number: 12366767Abstract: Described herein are systems and/or methods for designing a system of contact lenses with interocular refractive disparity (i.e. anisometropia) for presbyopes. An example method may comprise a step of determining a plurality of lenses for inclusion in a system of contact lenses for treating presbyopes. Each of the plurality of lenses may be configured for an optical correction and may have a power profile associated therewith. The plurality of lenses may be grouped based on the optical correction. Each of the lenses in a particular group may have a different power profile. The example method may comprise a step of creating, based at least on the plurality of lenses and an add need, a fit guide. The fit guide may provide an interocular disparity of effective add. The interocular disparity of effective add may be determined by optimizing cyclopean performance across a range accommodative demands and light levels.Type: GrantFiled: April 21, 2020Date of Patent: July 22, 2025Assignee: Johnson & Johnson Vision Care, Inc.Inventors: Derek Dean Nankivil, Benjamin Wooley
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Patent number: 12357505Abstract: In one embodiment, a phacoemulsification system includes a phacoemulsification probe configured to be inserted into an eye, and including a needle, a horn configured to support the needle, and an ultrasonic actuator connected to the horn and configured to vibrate the needle to emulsify a lens of the eye, an aspiration line partially disposed in the needle, a pumping sub-system connected to the aspiration line and configured to remove fluid and waste matter from the eye via the aspiration line, a valve disposed in the aspiration line and configured to control fluid connectivity in the aspiration line, a sensor configured to provide a signal indicative of a fluid metric in the aspiration line, and a controller configured to find an activation status of the ultrasonic actuator, and selectively control the valve responsively to the fluid metric and the activation status of the ultrasonic actuator.Type: GrantFiled: October 26, 2021Date of Patent: July 15, 2025Assignee: Johnson & Johnson Surgical Vision, Inc.Inventors: Vadim Gliner, Alon Boumendil
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Patent number: 12345964Abstract: Ophthalmic lenses are described herein. An example ophthalmic lens may comprise a first surface. The example ophthalmic lens may comprise a second surface disposed opposite the first surface and defining a volume of lens material therebetween. A thickness profile of the volume of lens material may be derived from one or more eyelid profiles such that a thickness gradient of the volume of lens material is oriented to be substantially orthogonal to a target eyelid margin shape.Type: GrantFiled: April 8, 2022Date of Patent: July 1, 2025Assignee: Johnson & Johnson Vision Care, Inc.Inventor: Benjamin Straker
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Patent number: 12338816Abstract: A system includes a pump, an inlet sensor, an outlet sensor, and a controller. The pump is configured for pumping fluid in a phacoemulsification system. The inlet sensor is coupled with an inlet port of the pump and is configured to sense an inlet temperature of the fluid at the inlet port. The outlet sensor is coupled with an outlet port of the pump and is configured to sense an outlet temperature of the fluid at the outlet port. The controller is configured to take a responsive action based a difference between the inlet temperature and the outlet temperature crossing a defined threshold.Type: GrantFiled: July 26, 2021Date of Patent: June 24, 2025Assignee: Johnson & Johnson Surgical Vision, Inc.Inventor: Assaf Govari
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Patent number: 12331146Abstract: Provided are polymer compositions made by a process comprising: (a) providing a first reactive composition containing: (i) a polymerization initiator that is capable, upon a first activation, of forming two or more free radical groups, at least one of which is further activatable by subsequent activation; (ii) one or more ethylenically unsaturated compounds; and (iii) a crosslinker; (b) subjecting the first reactive composition to a first activation step such that the first reactive composition polymerizes therein to form a crosslinked substrate network containing a covalently bound activatable free radical initiator, (c) combining the crosslinked substrate network with a second reactive composition containing one or more ethylenically unsaturated compounds; and (d) activating the covalently bound activatable free radical initiator of the crosslinked substrate network such that the second reactive composition polymerizes therein with the crosslinked substrate network to form a grafted polymeric network and aType: GrantFiled: October 12, 2023Date of Patent: June 17, 2025Assignee: Johnson & Johnson Vision Care, Inc.Inventors: Brian Aitken, Charles Scales, Scott Joslin, Yong Zhang, Dola Sinha, Shivkumar Mahadevan, Patricia Martin, Fang Lu, Donnie Duis, Stephen C. Arnold
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Patent number: 12329681Abstract: A handpiece for ocular surgery that includes a handle having at least inlets for irrigation and aspiration; a sleeve extending distally from a first end of the handle, wherein the sleeve comprises a bore extending a length of the sleeve along a central axis of the sleeve, and includes at least one port suitable to deliver irrigation from the irrigation inlet substantially distal from the first end of the handle; the aspiration being provided between an aspiration inlet and a distal bore port; a motor coupled with a second end of the handle and having a shaft; and an auger associated with the shaft, and extending at least partially through an interior portion of the handle between the second and the first ends and extending along the length of the sleeve, wherein a tip of the auger distal to the shaft is advanced by actuation of the motor.Type: GrantFiled: July 17, 2019Date of Patent: June 17, 2025Assignee: Johnson & Johnson Surgical Vision, Inc.Inventor: Lauren M. Hickey
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Patent number: 12329680Abstract: A system and method for provided a phacoemulsification surgery handpiece including a convertible sleeve for phacoemulsification surgery and irrigation/aspiration procedures. In a retracted state, the sleeve is in a desired relationship with the exposed portion of a phaco tip of the handpiece to support normal phacoemulsification surgery. In an extended state, the sleeve features a distally placed aspiration hole located forward from the distal end of a phaco tip to allow typical irrigation/aspiration procedures. A distal tip segment of the hand piece is overmolded by polyimide materials having a split feature to allow egress of a phaco tip.Type: GrantFiled: July 8, 2021Date of Patent: June 17, 2025Assignee: Johnson & Johnson Surgical Vision, Inc.Inventors: Harkirat S. Jandu, Mark W. Ross
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Patent number: 12324770Abstract: A method for calibrating a probe includes applying respective harmonic electrical signals having respective amplitudes and respective phases to multiple piezoelectric crystals coupled with a tip of the probe so as to cause the tip to vibrate, observing a motion of the tip while applying the respective harmonic electrical signals, adjusting the respective amplitudes and the respective phases of the signals so as to cause the observed motion of the tip to conform to a predefined trajectory, and recording an indication of the respective, adjusted amplitudes and phases in a memory contained in the probe.Type: GrantFiled: April 15, 2021Date of Patent: June 10, 2025Assignee: Johnson & Johnson Surgical Vision, Inc.Inventor: Vadim Gliner
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Patent number: 12321044Abstract: Described herein are systems and/or methods for forming an ophthalmic lens. An example method may comprise a step of determining a power profile based on a power profile function defined by a base optical power, an amount of spherical aberration at a radial distance from a geometric center of the lens, and a bump function. The example method may comprise a step of adjusting the power profile based at least on minimizing a shape metric of a through-focus curve.Type: GrantFiled: October 17, 2023Date of Patent: June 3, 2025Assignee: Johnson & Johnson Vision Care, Inc.Inventors: Xin Wei, Philippe F. Jubin, Derek Nankivil, Minghan Chen, Gregory Williby
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Patent number: 12318532Abstract: A pressure and vacuum pump including at least two diaphragm pump heads for providing vacuum and pressure simultaneously. The dual function pump reduces number of required pumps, is traditionally quieter, and enables the system to run at a lower duty cycle. A drive in the pump housing causes a connecting rod to oscillate a diaphragm to move up and down thereby causing air to be either drawn into an inlet or forced out via an exhaust.Type: GrantFiled: December 16, 2020Date of Patent: June 3, 2025Assignee: Johnson & Johnson Surgical Vision, Inc.Inventors: Nader Nazarifar, Justin Lin, Deep Mehta
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Patent number: 12299783Abstract: A phacoemulsification system having an imaging device configured to capture images of an eye and a phacoemulsification probe, a display, and a processor configured to receive an eye scan result providing a two-dimensional array of cataract thicknesses of the eye, find cutlines through which to cut the cataract into sections responsively to the two-dimensional array of cataract thicknesses, and render the images of the eye and the phacoemulsification probe with representations of the found cutlines through which to cut the cataract into sections to the display.Type: GrantFiled: May 10, 2022Date of Patent: May 13, 2025Assignee: Johnson & Johnson Surgical Vision, Inc.Inventors: Yael Buchnik, Vadim Gliner
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Patent number: 12293832Abstract: Risk prediction models are trained and deployed to analyze images, such as computed tomography scans, for predicting risk of lung cancer (e.g., current or future risk of lung cancer) for one or more subjects. Individual risk prediction models are trained on nodule-specific and non-nodule specific features, including longitudinal nodule specific and longitudinal non-nodule specific features, such that each risk prediction model can predict risk of lung cancer across different time horizons. Such risk prediction models are useful for developing preventive therapies for lung cancer by enabling clinical trial enrichment.Type: GrantFiled: July 13, 2022Date of Patent: May 6, 2025Assignee: Johnson & Johnson Enterprise Innovation Inc.Inventors: George R. Washko, Jr., Christopher Scott Stevenson, Samuel Yoffe Ash, Raul San Jose Estepar, Matthew David Mailman
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Patent number: 12285360Abstract: A phacoemulsification apparatus includes a phacoemulsification probe, an electromechanical valve, and an electromechanical mechanism. The probe having a fluid channel for exchanging fluid with a patient's eye. The electromechanical valve is coupled with the fluid channel and is configured to regulate a fluid flow through the fluid channel. The valve including a cylinder, a piston inside the cylinder, wherein the piston divides the cylinder into a first cavity that is in fluid communication with the fluid channel, and a second cavity, and one or more fluid communication links, which are formed between the first and second cavities. The piston is configured to move inside the cylinder to regulate the flow of the fluid, and the one or more fluid communication links are configured to allow the fluid to flow between the first and second cavities during motion of the piston. The electromechanical mechanism is configured to move the piston.Type: GrantFiled: December 22, 2020Date of Patent: April 29, 2025Assignee: Johnson & Johnson Surgical Vision, Inc.Inventors: Yehuda Algawi, Assaf Govari, Eran Aharon, Ilya Sitnitsky, Stanislav Katzir
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Patent number: 12263121Abstract: A system includes a needle, an actuator assembly and a generator. The needle is configured to be vibrated so as to emulsify a lens of an eye. The actuator assembly, includes a first actuator, a second actuator and a third actuator, which are distributed around a longitudinal axis of the needle and are configured to vibrate along the longitudinal axis in response to a first driving signal, a second driving signal and a third driving signal, respectively. The generator is configured to generate the first driving signal, the second driving signal and the third driving signal, so as to vibrate the needle in accordance with a predefined pattern.Type: GrantFiled: April 9, 2024Date of Patent: April 1, 2025Assignee: Johnson & Johnson Surgical Vision, Inc.Inventors: Assaf Govari, Vadim Gliner
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Patent number: 12257133Abstract: A doming tool for manufacturing absorbent tampon includes a plurality of stations made of devices for shaping a tampon pledget tip, and a hollow mandrel engaging with the stations. The stations are supported by at least one mounting plate.Type: GrantFiled: March 4, 2024Date of Patent: March 25, 2025Assignee: Johnson & Johnson GmbHInventors: Nick Brooks, Peter Morgan, James Stembridge, Trevor Whales
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Patent number: 12257134Abstract: A press for shaping an absorbent tampon blank into a shaped tampon pledget includes a central cavity arranged and configured to accommodate an absorbent tampon blank having a front portion and a back portion. The main longitudinal axis of the press passes in the middle of the central cavity and a plurality of penetrating dies are arranged radially around the said main longitudinal axis. Each penetrating die has a pressing face on at least a fragment of its side facing the central cavity. The said press comprises at least one cam to actuate the plurality of penetrating dies. Furthermore, the plurality of penetrating dies comprises at least one penetrating die having a pressing face with a first shaped longitudinal profile, and least one penetrating die having a pressing face with a second shaped longitudinal profile.Type: GrantFiled: March 14, 2024Date of Patent: March 25, 2025Assignee: Johnson & Johnson GmbHInventors: Nick Brooks, David L. Kimball, Peter Morgan, James Stembridge
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Patent number: 12256910Abstract: The present invention comprises a heel insert for use with a phacoemulsification foot pedal that may shift a surgeon's foot forward on the treadle of a foot pedal to reduce the force required to actuate the foot pedal. The present invention may be easily attachable and removable and may provide a less complicated and alternative foot position for surgeons preferring different treadle mechanics.Type: GrantFiled: May 25, 2021Date of Patent: March 25, 2025Assignee: Johnson & Johnson Surgical Vision, Inc.Inventors: Jourdan Colter, Brennen Wears, Stephen Christopher
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Patent number: 12257185Abstract: A system and method for provided a phacoemulsification surgery handpiece including a convertible sleeve for phacoemulsification surgery and irrigation/aspiration procedures. In a retracted state, the sleeve is in a desired relationship with the exposed portion of a phaco tip of the handpiece to support normal phacoemulsification surgery. In an extended state, the sleeve features a distally placed aspiration hole located forward from the distal end of a phaco tip to allow typical irrigation/aspiration procedures. A distal tip segment of the hand piece is overmoldedby polyimide materials having a split feature to allow egress of a phaco tip.Type: GrantFiled: July 8, 2021Date of Patent: March 25, 2025Assignee: Johnson & Johnson Surgical Vision, Inc.Inventors: Harkirat S. Jandu, Mark W. Ross
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Patent number: 12239730Abstract: The present disclosure relates to leave-on light oil hair compositions that comprise a blend of non-cyclic silicone and non-silicone ingredients. The leave-on light oil hair compositions, which do not contain D4, D5 or D6 silicones, are particularly useful in methods for imparting durable resistance to breaking, frizz control, shine and/or volume definition with a soft feel to hair.Type: GrantFiled: March 25, 2020Date of Patent: March 4, 2025Assignee: Johnson & Johnson Consumer Inc.Inventors: Euen Ekman-Gunn, Ana Carolina Nogueira