Abstract: Described is a silicone hydrogel contact lens having non-uniform morphology. The contact lens may be made from a reactive mixture comprising: a silicone-containing component; a hydrophilic component; a non-reactive polymeric internal wetting agent; and a polymerization initiator, the contact lens having an oxygen permeability of at least about 60 barrers, and wherein the molar ratio in the lens of the polymeric non-reactive internal wetting agent to silicone, without a surface treatment, is greater in the lens's surface than in its bulk.

Abstract: A molded contact lens comprising a stiffer optic zone relative to the peripheral zone of the contact lens provides an optical element for correcting astigmatism without the need for or substantially minimizing the need for the correction of rotational misalignment. The higher elastic modulus optic zone vaults over the cornea thereby allowing a tear lens to form. The tear lens follows or assumes the shape of the back surface of the contact lens. The combination of the tear lens and the optical zone provide an optical element for correction of refractive error.

Abstract: Described are polymerizable high energy light absorbing compounds. The compounds absorb various wavelengths of ultraviolet and/or high energy visible light and are suitable for incorporation in various products, such as biomedical devices and ophthalmic devices.

Abstract: Described herein are systems and/or methods for forming an ophthalmic lens. An example method may comprise a step of determining a power profile based on a power profile function defined by a base optical power, an amount of spherical aberration at a radial distance from a geometric center of the lens, and a bump function. The example method may comprise a step of adjusting the power profile based at least on minimizing a shape metric of a through-focus curve.

Abstract: The present invention is directed to a flowable hemostatic paste comprising a crosslinked carboxymethyl cellulose and at least one non-toxic dispersant. More specifically the present invention relates to a hemostatic paste containing citric acid cross-linked CMC, which is suspended or dispersed as a powder in a mixture of a first non-toxic glycerol-containing hygroscopic dispersant and a second non-toxic alcohol functionalized dispersant comprising propylene glycol or 1,3-butanediol.

Abstract: Provided are compounds described by the Formula I: wherein: R1 is a linear or branched, saturated or unsaturated aliphatic group having from 5 to 22 carbon atoms; R2 is selected from the group consisting of the functional groups: —NH2; and salts thereof; n is from 0 to 4; and R3 is a linear or branched, saturated or unsaturated aliphatic group having from 1 to 6 carbon atoms. Also provided are compositions comprising, and methods of use of, the compounds of the present invention.

Abstract: Provided are polymer compositions made by a process comprising: (a) providing a first reactive composition containing: (i) a polymerization initiator that is capable, upon a first activation, of forming two or more free radical groups, at least one of which is further activatable by subsequent activation; (ii) one or more ethylenically unsaturated compounds; and (iii) a crosslinker; (b) subjecting the first reactive composition to a first activation step such that the first reactive composition polymerizes therein to form a crosslinked substrate network containing a covalently bound activatable free radical initiator, (c) combining the crosslinked substrate network with a second reactive composition containing one or more ethylenically unsaturated compounds; and (d) activating the covalently bound activatable free radical initiator of the crosslinked substrate network such that the second reactive composition polymerizes therein with the crosslinked substrate network to form a grafted polymeric network and a

Abstract: In one embodiment, an irrigated medical system includes a medical tool, an irrigation line configured to fluidically connect an irrigation reservoir storing irrigation fluid to the medical tool, and provide at least some of the irrigation fluid to the medical tool, a force sensor configured to be coupled with the irrigation reservoir, and provide a signal responsively to a force exerted by the irrigation reservoir on the force sensor over time as irrigation fluid in the irrigation reservoir is depleted, and a controller configured to find an irrigation rate of the irrigation fluid flowing in the irrigation line responsively to the signal.

Abstract: The present invention relates to compositions comprising one or more extracts and/or compounds having retinol-like activity and properties and methods of using the compositions to treat the eye.

Abstract: An ocular surgical apparatus is provided, including a processor configured to receive ocular surgical data and a graphical user interface configured to display the ocular surgical data to a user. The processor configured to filter the ocular surgical data and the graphical user interface configured to display filtered ocular surgical data. The processor is configured to receive a number of ocular surgical data samples, discard selected ocular surgical data samples thereby yielding a number of emphasized samples, and perform an operation on the number of emphasized samples to produce filtered ocular surgical data.

Abstract: Disclosed are co-polymers which are produced from reactive monomer mixtures and which have both high refractive index and a high Abbe number. These materials are well suited for use as implantable ophthalmic devices and have a refractive index which may be edited through application of energy. When used for an intraocular lens, the high refractive index allows for a thin lens which compresses to allow a small incision size.

Abstract: A packaged elongate sanitary protection product includes a folded sanitary protection product enveloped in a substantially circular package and having first and second arcuate end portions comprising first and second ends, respectively, separated by a central portion. The topsheet and backsheet are joined in a flange surrounding the absorbent structure, and the absorbent structure comprises at least three intersecting, substantially circular sections aligned along a longitudinal axis. A first circular section is associated with the first arcuate end portion, and a second section is associated with the second arcuate end portion, and a central portion is associated with at least one intervening substantially circular portion. The intersections define folding axes perpendicular to the longitudinal axis and enlarged flange sections of the topsheet and backsheet. The product is folded at the fold lines and the enlarged flange sections are folded inwardly to give the product a generally circular form.