Abstract: A method for detecting glutathione includes mixing a sample including glutathione, 9-bromomethyl acridine (Br-MA) and a derivatization solvent to form a reaction solution. A derivative reaction occurs between Br-MA and glutathione to obtain a derivatization solution including a glutathione derivative with a thiol group being substituted with a tag. Excess Br-MA is removed by adding an interference removing solvent into the derivatization solution, followed by vortexing and centrifugation to obtain an aqueous layer solution. The aqueous layer solution is used as an analytic solution, and the glutathione derivative in the analytic solution is detected to obtain a glutathione value. The present invention also provides a kit for detecting glutathione which is adapted to carry out the method for detecting glutathione.

Abstract: The present disclosure discloses a ceramic material having a positive slow release effect and a method for manufacturing the same. The ceramic material comprises a hierarchically meso-macroporous structure which composition at least includes silicon and oxygen, wherein the hierarchically meso-macroporous structure includes a plurality of macropores and a wall having a plurality of arranged mesopores, and the plurality of macropores are separated by the wall; and nano-scale metal particles confined in at least one of the plurality of arranged mesopores. The nano-scale metal particles have a positive slow release effect from the at least one of the plurality of arranged mesopores. The ceramic material has a property of inhibiting growth of microorganisms or killing the microorganisms in an environment or a system containing a hydrophilic medium.

Abstract: A method for detecting whether glucose metabolism is abnormal comprises: detecting GPx2 gene expression, GPx2 protein expression or the activity of GPx2 protein in a test body, and making comparisons with GPx2 expression amount of a normal individual, when the GPx2 expression of the individual is significantly lower than that of the normal individual, indicating that the carbohydrate metabolism of the individual is in an abnormal state. Applications of GPx2 in the preparation of a medical composition for the treatment and prevention of type II diabetes.

Abstract: Disclosed herein is a bi-specific antibody that specifically directs a therapeutic agent to a cancer cell by targeting a tumor antigen of the cancer cell, and thereby suppressing the growth of the cancer or blocking the invasion or metastasis of the cancer. The bi-specific antibody of the present disclosure includes a first antigen binding site that binds to polyethylene glycol (PEG); and a second antigen binding site that binds to a target ligand, such as a tumor antigen.

Abstract: An automatic cell isolation and collection system for sorting out target cells from a sample includes a crush module, a centrifuge module, a transport module, and a control unit. The centrifuge module includes centrifuge tubes and a magnetic mechanism providing a magnetically attractive force to at least one of the centrifuge tubes. The control unit electrically communicates with the crush module, the centrifuge module, and the transport module, and controls operation of the crush module, transport of the sample via the transport module after the sample is crushed by the crush module, centrifugation of the centrifuge module, and operation of the magnetic mechanism for providing the magnetically attractive force.

Abstract: A method of treating a subject suffering from an angiogenesis-related disease, which is implemented by administering to the subject a pharmaceutical composition comprising a compound of formula I derived from Mitella formosana to inhibit the angiogenic function of endothelial progenitor cells.

Abstract: Disclosed herein are methods of detecting or making a risk evaluation of a cancer that has a mutated PREX2 expressed thereon. The cancer may be a primary cancer, a metastatic cancer or a recurrent cancer. According to the embodiment of the present disclosure, the mutation is G258V, S1113R, E1346D or K400fs. Also disclosed herein are methods of treating the subject in need thereof.

Abstract: The present disclosure discloses a ceramic material having a positive slow release effect and a method for manufacturing the same. The ceramic material comprises a hierarchically meso-macroporous structure which composition at least includes silicon and oxygen, wherein the hierarchically meso-macroporous structure includes a plurality of macropores and a wall having a plurality of arranged mesopores, and the plurality of macropores are separated by the wall; and nano-scale metal particles confined in at least one of the plurality of arranged mesopores. The nano-scale metal particles have a positive slow release effect from the at least one of the plurality of arranged mesopores. The ceramic material has a property of inhibiting growth of microorganisms or killing the microorganisms in an environment or a system containing a hydrophilic medium.

Abstract: The present invention relates to a use of Discoidin Domain Receptor 1 (DDR1) inhibitor in preparing a medicament for preventing or treating a joint disease. The present invention further relates to a use of DDR1 activator in preparing a medicament for preventing or treating abnormalities of endochondral ossification-related conditions.

Abstract: Provided is a device for rapidly isolating cells from tissue, comprising: a stirring and cutting member, having a rotary cutting tool, wherein same is driven by a motor so as to rotate to stir and cut tissue, and can inject digestive enzymes to accelerate decomposition of the tissue; and double-layered nested cups comprising an inner cup and an outer cup, used for accommodating and filtering solution of required cells, wherein a filter device of the inner cup screens out the required cells, and the outer cup collects the filtered solution.

Abstract: A multi-axis measurement device for loading force and center of gravity is provided comprising a first loading plate, and comprising: a first slidable element and a first piezoelectric pressure sensing element. A second loading plate comprising: a second slidable element and a second piezoelectric pressure sensing element. A connecting plate, respectively connects to the first slidable element, the first piezoelectric pressure sensing element, the second slidable element, and the second piezoelectric pressure sensing element. A plurality of third piezoelectric pressure sensing elements connects to the first loading plate. The first piezoelectric pressure sensing element measures the changes in force of the X-axis direction, the second piezoelectric pressure sensor element sensing element measures the changes in force of the Y-axis direction, and the third piezoelectric pressure sensor element sensing elements measure the changes in force of the Z-axis direction.

Abstract: A device is provided for opening mouth. The device is custom-made through 3-dimensional (3D) printing. The overall framework is printed out after 3D-scanning the oral cavity, which meets a patient's oral shape. The present invention practically and effectively fabricates a custom-made mouth-opening device. The mouth's structure changed after surgery is taken into consideration, so that the patient can easily open the mouth with one hand. Furthermore, because the weight overall is light, the whole single-hand operation feels no heavy. The prolonged work of dental rehabilitation required by the patient is met. The device is easy to be cleaned. The feature of high material strength yet with proper softness is achieved. The comfort of use is increased for the patient with life quality enhanced. The effectiveness of rehabilitation and intervention is improved. The cost of custom-made medical material is effectively reduced.

Abstract: A rotary shaver for tissue resection includes an elongated outer tubular member, an elongated inner cutting member disposed in and operatively rotatable relative to the outer tubular member for cutting a tissue, and an elongated jaw member disposed in the outer tubular member to surround the inner cutting member and operatively turnable to cooperate with an outer distal portion of the outer tubular member so as to clamp and electrocauterize the tissue for creating hemostasis during a surgical procedure.

Abstract: This invention is announcing a composition of flavonoid skeleton in the formula I or formula II compound, wherein each of the substituents is given the definition as set forth in the specification and claims. This composition has the capacity to treating or preventing a virus infection in a subject.

Abstract: This invention provides a guide for surgical purpose, comprising: a long column body, being in a hollow shape, an upper side thereof having a semi-cylinder, a bottom side thereof having a cuboid, and an inside thereof being provided with an elongated slot, in which an interior of the semi-cylinder is in communication with an interior of the cuboid; a wing-shaped part, being in a wing shape, and disposed at one end of the long column body and engaged with one side of the cuboid and extending from both ends of the one side of the cuboid, for grasping during surgery; a limiting piece, being in a ring shape and socketing the other end of the long column body and engaging with the other side of the cuboid, for withstanding the tissues during surgery; and a replaceable expander, being disposed in the elongated slot, for expanding and opening a surgical incision of tissues, wherein the replaceable expander is replaceable with another expander of different dimension in a stepwise manner via the one side of the cuboid

Abstract: A vestibular system examination device includes a platform unit and an examination unit. The platform unit includes abase, a driving mechanism mounted to the base, and a seat mounted to the driving mechanism and adapted for a user to sit thereon. The seat is driven movably and rotatably with six degrees of freedom by the driving mechanism. The examining unit includes a detector adapted for detecting eye movement or electrooculography of the user, a measuring module electrically connected to the platform unit for measuring location and displacement thereof, and a processing module electrically connected to the detector and the measuring module for receiving and processing data acquired from the detector and the measuring module.

Abstract: The present invention provides a method for determining a survival rate and prognosis state and providing care for a patient having esophageal carcinoma, comprising: (a) providing a tissue sample from the patient; (b) measuring an expression level of a plurality of target genes comprising peptidase inhibitor 3 (PI3) and CD14 in the tissue sample from the patient using reagents specific for a gene product of the plurality of target genes that are selected from the group consisting of probes, primers, antibodies, and antibody fragments, wherein the expression level is measured by RNA expression or protein expression; (c) comparing the expression level of the plurality of target genes to a predetermined threshold indicative of a survival rate and prognosis state for the patient; and (d) providing care for the patient when the survival rate and prognosis state is worse, wherein the care is advising the patent to reduce the time between return visit or to add adjuvant chemotherapy after surgery.

Abstract: A bone nail apparatus includes a bone nail, a light source unit and a focalizing unit. The bone nail has a tube wall and at least one through hole. The tube wall is enclosed to form a receiving space. The at least one through hole extends through the tube wall and communicates with the receiving space. The light source unit includes a light emitter and at least one light transmission tube. The at least one light transmission tube is connected to the light emitter and receives a light therefrom. The at least one light transmission tube is received in the receiving space of the bone nail. Each light transmission tube has a light-outputting end aligned with a respective one of the at least one through hole. The focalizing unit has a light-receiving face facing one of the at least one through hole.

Abstract: The present invention discloses a method to determine whether a warning sign will occur in a subject with the Flavivirus infectious illness, and a pharmaceutical composition. The method includes steps of measuring the level of serum hyaluronan of the subject, and determining that the warning sign will occur in his/her illness course when the level is higher than or equal to 70 ng/mL. It is identified in the invention that the level of the serum hyaluronan is an excellent predicator for the severity of the Flavivirus infectious illness.

Abstract: This invention is announcing a composition of flavonoid skeleton in the formula I or formula II compound, wherein each of the substituents is given the definition as set forth in the specification and claims. This composition have the capacity to treating or preventing a virus infection in a subject.