Abstract: A culture medium for inducing a pluripotent stem cell into a differentiation-promoted pluripotent stem cell, the medium including a Glycogen synthase kinase 3? (GSK3?) inhibitor, a Bone morphogenic protein (BMP) signaling inhibitor, and a Transforming growth factor (TGF)-? inhibitor as active ingredients.

Abstract: A mobile body control device includes: an observation trajectory acquisition unit that acquires, a trajectory along which the subject walks; a basic trajectory acquisition unit that acquires, a basic trajectory that matches the observation trajectory; a subject predicted trajectory acquisition unit that acquires a trajectory along which the subject walks after the current time point based on the specific basic trajectory; a prediction reliability calculation unit that calculates a prediction reliability based on uncertainty added along the subject predicted trajectory; a target trajectory acquisition unit that acquires, a trajectory formed by a target position of a mobile body set ahead of the subject in a traveling direction of the subject; and a control-command-sequence-generating unit that generates a control command sequence using an evaluation function that uses as input the subject predicted trajectory, prediction reliability, target trajectory, and a control trajectory.

Abstract: Disclosed is a method for evaluating cell differentiation state, including inducing pluripotent stem cells to differentiate into mesodermal cells in a liquid medium by a first differentiation treatment for inducing pluripotent stem cells to differentiate into mesodermal cells and a second differentiation treatment for inducing the mesodermal cells to differentiate into cardiomyocytes; collecting a supernatant of the liquid medium comprising cells induced to differentiate by the second differentiation treatment; and measuring miRNA-3p in miR-1/133a cluster in the supernatant, where the miRNA-3p is at least one selected from a group consisting of miR-1-3p and miR-133a-3p, and the measured value of miRNA-3p is an index of differentiation into cardiomyocytes.

Abstract: An object of the present invention is to provide further assistance in addition to assistance by tactile force transmission. An information presentation system includes a master device to which an operation by an operator is input and a slave device that operates in accordance with the operation input to the master device. Furthermore, the information presentation system includes a tactile force transmission unit, a calculation unit, and a presentation unit. The tactile force transmission unit controls tactile force transmission in the master device and the slave device. The calculation unit calculates physical characteristics of a substance in contact with the slave device on the basis of an external force input from the environment to the slave device while the slave device maintains a predetermined motion state. The presentation unit presents the physical characteristics of the substance calculated by the calculation unit.

Abstract: An object of the present invention is to make control for friction compensation executed in a master-slave system more appropriate. A control system includes a master device, a slave device, and a control device. Furthermore, the control device includes a friction compensation control unit and a tactile force transmission unit. The friction compensation control unit calculates a force for assisting an operation in the master device with respect to friction generated in the slave device on the basis of a moving average of velocity of a movable portion in the slave device. The tactile force transmission unit assists the operation in the master device with a force calculated by the friction compensation control unit and controls tactile force transmission in the master device and the slave device.

Abstract: [Problem to be solved by the invention] The purpose of the present invention is to provide a competitive immunochromatographic analysis method and immunochromatographic sensor using said analysis method capable of intuitively displaying a molecular concentration of a substance to be measured and facilitating visual judgement of the molecular concentration.

Abstract: Provided is a pharmaceutical composition effective for anti-cancer immunostimulating therapies.

Abstract: There are many options in cancer evaluation and treatment, and it is desired to ascertain the characteristics and conditions of individual patients and improve treatment efficacy and cost performance. Provided is a method for providing information pertaining to a cancer in a subject using an indicator based on the amount of D-amino acid in a biological sample from the subject, wherein the information is selected from the group consisting of: a verification result of the validity of a test or diagnosis result of the cancer in the subject; a classification of the degree of progression of the cancer in the subject; a result of a prognosis prediction for the cancer in the subject; and information for selecting a treatment means for the cancer in the subject. Also provided is a system for providing information pertaining to a cancer in a subject.

Abstract: A vibration-driven energy harvesting device includes a vibration-driven energy harvesting element that generates power according to vibrations of an electrode; an output unit that, when connected to a load resistor, extracts power generated by the vibration-driven energy harvesting element; a judgment unit that judges whether or not a power value of the power is greater than a predetermined threshold value; a determination unit that determines an input impedance of the output unit based on a judgment result obtained by the judgment unit; and an adjustment unit that adjusts the input impedance of the output unit according to a determination made by the determination unit.

Abstract: A feature amount extractor extracts a feature amount representing the feature of a brain wave from the brain wave of a subject, the brain wave being measured when a magnetic stimulation is applied to the brain of the subject. A mental disorder determiner determines whether or not the subject has a predetermined mental disorder on the basis of a feature amount variation that is a differential value between a feature amount extracted from a brain wave measured immediately before the magnetic stimulation and a feature amount extracted from a brain wave measured immediately after the magnetic stimulation.

Abstract: A composition for decomposition of trypsin or TMPRSS2 containing, as an active ingredient, bacteria that have 00502 protein, or a protein having 30% or higher sequence identity with an amino acid sequence of the 00502 protein and having a trypsin-binding ability; or bacteria that have 00509 protein, or a protein having 30% or higher sequence identity with an amino acid sequence of the 00509 protein and having a trypsin-binding ability.

Abstract: An object of the present invention is to provide an anti-human norovirus agent which can inhibit infection with and proliferation of human norovirus. The present inventors have found that the object can be attained through provision of an anti-human norovirus agent comprising a fucose analog having an inhibitory action on glycosylation by fucosyltransferase (FUT) as an active ingredient. Examples of the active ingredient include a fucose analog represented by formula (III) or (IV) or a salt thereof: [In the formulas, each of formula (III) and formula (IV) represents an ?-anomer or a ?-anomer; each of R1, R3, and R4 is —OH or —OAc; R2 is a halogen atom, —OH, or —OAc; and R5 is —CH3, —C?CH, —C?CCH3, or —CH2C?CH.

Abstract: In related-art methods of differentiating pluripotent stem cells into a desired cell type, there has not been established a differentiation induction method using human ES/iPS cells and being highly efficient. Many attempts have been made, including a stepwise differentiation induction method based on the control of culture conditions or the addition of, for example, various cell growth factors/differentiation factors to a culture solution, but the use of complicated culture steps is a big problem. A method of inducing differentiation into a desired cell type within a short period of time and with high efficiency by use of a pluripotent stem cell that actively undergoes cell differentiation, which is obtained by reducing an undifferentiated state of the pluripotent stem cell, has been developed, and thus the present invention has been completed.

Abstract: A control system includes a master device, a slave device, and a control device. Furthermore, the control device includes a tactile force transmission unit and a mode setting unit. The tactile force transmission unit controls tactile force transmission in the master device and the slave device. The mode setting unit changes an amplification factor of force transmitted from the slave device to the master device in a specific section in which a moving element of the slave device moves on the basis of a physical quantity in the moving element of the slave device.

Abstract: A data generation device includes: a parameter generator; and a reaction force data generator. The parameter generator generates value data based on a signal having a correlation with a driving force. The parameter generator generates velocity data based on a signal representing a response of a member driven by the driving force. The reaction force data generator generates data of a reaction force received by the member from a predetermined object based on the value data and the velocity data.

Abstract: The present invention provides a prophylactic and/or therapeutic agent for inflammatory disease including a compound or a salt thereof, or a solvate thereof, the compound represented by a formula (1): [where each sign is defined as described in the description] as an active ingredient.

Abstract: A position/force control system includes a worn unit and a control unit. The worn unit is configured to be worn on a body of a user, and provides force tactile sensation by an actuator. The control unit acquires data of a position of the worn unit in a space, based on data of space in which a touching object exists. The worn unit includes a control unit that acquires the data of the position from the control unit and controls driving of the actuator based on impedance and contour information of the touching object in the space, and the data of the position, thereby providing force tactile sensation.

Abstract: The present inventors have found that the content ratios of isoalloLCA, 3-oxoLCA, alloLCA, and 3-oxoalloLCA in the feces of centenarians are higher than those of younger ones, and have also identified gut microbiomes peculiar to centenarians involved in the production of these bile acids. Furthermore, it has been found that these bile acids, enzymes involved in the production thereof, and bacteria producing the enzymes reduce the risk of infection with pathogens, prostate cancer, and the like, and are involved in longevity.

Abstract: In related-art methods of differentiating pluripotent stem cells into a desired cell type, there has not been established a differentiation induction method using human ES/iPS cells and being highly efficient. Many attempts have been made, including a stepwise differentiation induction method based on the control of culture conditions or the addition of, for example, various cell growth factors/differentiation factors to a culture solution, but the use of complicated culture steps is a big problem. A method of inducing differentiation into a desired cell type within a short period of time and with high efficiency by use of a pluripotent stem cell that actively undergoes cell differentiation, which is obtained by reducing an undifferentiated state of the pluripotent stem cell, has been developed, and thus the present invention has been completed.

Abstract: A cell preparation for treating brain tumors used in combination with a prodrug that is converted to 5-fluorouracil by cytosine deaminase, wherein the cell preparation comprises neural stem cells derived from pluripotent stem cells having a cytosine deaminase gene and a uracil phosphoribosyltransferase gene is provided to establish new means for treating brain tumors.