Abstract: A haptic transmission system includes a master device and a slave device. The master device controls position and force in an operation of the master device based on information acquired from the operation of the master device and information relating to a response of the slave device, and compensates for a communication delay in a communication path with respect to the control of force. The slave device controls speed and force in an operation of the slave device based on information acquired from the operation of the slave device and information relating to control from the master device.
Type:
Grant
Filed:
March 7, 2019
Date of Patent:
June 25, 2024
Assignees:
KANAGAWA INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGY, KEIO UNIVERSITY
Abstract: Sample preparation system and method which enable electron microscope observation of a sample slice with simple structure and process are provided. The sample preparation system includes at least one of a plasma treatment apparatus and a sputtering apparatus, as well as a slice collecting apparatus. The plasma treatment apparatus is configured to feed a resin tape in a plasma irradiation area to irradiate the resin tape with plasma, thereby continuously hydrophilizing the resin tape. The sputtering apparatus is configured to feed the resin tape in a sputtering area to continuously perform sputtering on the resin tape, thereby imparting conductivity to the resin tape. The slice collecting apparatus is configured to serially collect slices cut out from a sample onto the resin tape having been subjected to plasma treatment or sputtering.
Type:
Grant
Filed:
December 26, 2019
Date of Patent:
May 21, 2024
Assignees:
SANYU ELECTRON CO., LTD., KEIO UNIVERSITY
Abstract: Provided is a method of differentiating a pluripotent stem cell of mammalian origin into a desired cell type by predicting the direction of cell differentiation to be caused by induction of expression of a transcription factor. A human gene expression correlation matrix using human cells has been newly created, and further, it has been confirmed that human pluripotent stem cells can be differentiated into a desired cell type by introducing, into the human pluripotent stem cells, a transcription factor cocktail selected from the matrix.
Abstract: A passive wireless tag to identify a given command which has been received, even while responding to a wireless tag communication device. In this wireless tag, radio waves serving as a predetermined command are received from a wireless tag communication device via an antenna and an RF switch. Signal components are detected from the received radio waves by the detection circuit. The detected signal components are sampled by the sampling circuit in accordance with the timing when the RF switch is controlled to its ON state by a predetermined control signal. The time interval of the ON state is set to be sufficiently shorter than a transfer cycle of the received radio waves. The control circuit thus identifies the foregoing predetermined command according to the sampling results obtained from the sampling circuit.
Abstract: A symptom determination apparatus according to the present embodiment includes an EEG feature detection section and a symptom determination section. The EEG feature detection section detects one or a plurality of frequency components of an EEG signal in a certain brain area of a subject. The symptom determination section determines a depressive symptom in the subject based on the intensity of the one or plurality of frequency components of the EEG signal detected by the EEG feature detection section.
Abstract: A biometric information processing device (1) includes a brain wave detecting unit (10), a control unit (20), and a movement assisting unit (30). The brain wave detecting unit (10) detects biometric information in at least one brain region from among a plurality of brain regions that are selectable in accordance with a body part that is a target of function recovery or function improvement. The control unit (20) determines, based on the detected biometric information, at least one activity state in the brain including the location of the brain region(s) that is (are) activated in a subject while attempting to move the body part, and an activation level of such activated brain region(s). When the control unit (20) determines that the at least one activated state of the brain satisfies a predetermined condition, the movement assisting unit (30) executes a predetermined motion to assist movement of the body part.
Abstract: A module and system are provided for reducing or suppressing ringing occurring in a digital signal to be transmitted. A transmission module Ma includes a transmitter 200a configured to transmit a digital signal, a transmission antenna 100a constituted by a metal plate, or by a conductor formed on an insulator, the transmission antenna 100a being configured to be electromagnetically or magnetically coupled to a reception antenna 100b of a non-contact reception module Mb for digital communication, and a resistor 400a connected in series between the transmitter 200a and the transmission antenna 100a. The resistor 400a has such a resistance value that the resistor 400a entirely blunts a waveform of the digital signal outputted from the transmitter 200a so as to reduce or suppress ringing occurring in the digital signal. The blunted digital signal is to be inputted into the transmission antenna 100a.
Abstract: A non-transitory computer-readable storage medium storing therein an information management program for causing a computer to execute a process comprises: receiving property information indicating a reliability of a post uploaded on the Internet and a digital signature generated from the property information; and storing the property information, to which identification information of the post and the digital signature are added, in a storage.
Abstract: The purpose of the present invention is to provide an agent for restoring a visual function or an agent for preventing the deterioration in a visual function, which has an excellent visual function restoring ability. The agent for regenerating a visual function or the agent for preventing the deterioration in a visual function according to the present invention contains, as an active ingredient, a chimeric protein having both an amino acid sequence for a microorganism-origin ion-transporting receptor rhodopsin and an amino acid sequence for an animal-origin G-protein-coupled receptor rhodopsin. The chimeric protein is preferably one in which an amino acid sequence for a cytoplasm-side second loop and/or a cytoplasm-side third loop in the amino acid sequence for the microorganism-origin ion-transporting receptor rhodopsin is substituted by an amino acid sequence for a cytoplasm-side second loop and/or a cytoplasm-side third loop in the G-protein-coupled receptor rhodopsin.
Type:
Grant
Filed:
September 1, 2017
Date of Patent:
March 19, 2024
Assignees:
Keio University, Nagoya Institute of Technology
Abstract: Provided is a method of culturing a human hepatic parenchymal cell, including culturing a human hepatic parenchymal cell in a medium containing: a culture supernatant of a human hepatic nonparenchymal cell; a Wnt signaling promoter; and a mitogenic growth factor.
Abstract: Provided is a method of differentiating a pluripotent stem cell of mammalian origin into a desired cell type by predicting the direction of cell differentiation to be caused by induction of expression of a transcription factor. A human gene expression correlation matrix using human cells has been newly created, and further, it has been confirmed that human pluripotent stem cells can be differentiated into a desired cell type by introducing, into the human pluripotent stem cells, a transcription factor cocktail selected from the matrix.
Abstract: Provided herein are compositions and methods for the induction and/or proliferation of CD8+ T-cells. The disclosure also provides methods of treatment of diseases that can be treated by the induction and/or proliferation of CD8+ T-cells.
Type:
Application
Filed:
March 10, 2023
Publication date:
February 1, 2024
Applicants:
Keio University, The University of Tokyo
Inventors:
Kenya Honda, Takeshi Tanoue, Masahira Hattori, Yutaka Kawakami
Abstract: Provided are a spintronics device, a magnetic memory, and an electronics device capable of generating a large spin current without depending on a specific material. A spintronics device includes a first conductive layer, a second conductive layer having carrier mobility or electrical conductivity lower than that of the first conductive layer, and a boundary region between the conductive layers. The boundary region has a gradient of carrier mobility or electrical conductivity, and a spin current is generated by rotation of a velocity field of an electron caused by the gradient.
Abstract: A method for producing a two-dimensional small intestinal organoid having a villus structure, the method including a step 1 of culturing a cell derived from a small intestinal epithelium in an extracellular matrix to obtain a three-dimensional small intestinal organoid, a step 2 of dispersing the three-dimensional small intestinal organoid and monolayer culturing on the extracellular matrix to obtain a two-dimensional small intestinal organoid, and a step 3 of further culturing the two-dimensional small intestinal organoid while letting a culture medium of the two-dimensional small intestinal organoid to flow so that the two-dimensional small intestinal organoid forms a villus structure.
Abstract: A pancreatic cancer detection method is provided, including: (a) bringing extracellular vesicles, which are in a body fluid sample derived from a subject into contact with one or more kinds of lectins; (b) measuring an amount of the extracellular vesicles bound to the one or more kinds of lectins after (a); and (c) evaluating the presence of pancreatic cancer in the subject based on the amount of the extracellular vesicles measured in (b). In addition, a pancreatic cancer detection kit is provided, including: a solid-phase carrier on which one or more kinds of lectins are immobilized; and an antibody specifically binding to a pan-extracellular vesicle membrane protein or an antigen-binding fragment thereof.
Type:
Grant
Filed:
August 17, 2021
Date of Patent:
January 9, 2024
Assignees:
JVCKENWOOD CORPORATION, KEIO UNIVERSITY
Abstract: To identify a microorganism causing the development of primary sclerosing cholangitis associated with ulcerative colitis. A Klebsiella pneumoniae strain inducing inflammation in the liver.
Abstract: An information processing device (10) includes: a first acquisition section (12) that acquires input data; a generation section that generates, from the input data, reservoir input data which is to be input to a quantum reservoir (20) having a plurality of layers of sub-reservoirs; a second acquisition section (12) that acquires an output result of the quantum reservoir to which the reservoir input data has been input; and an output data generation section (14) that generates output data with reference to the output result.
Type:
Application
Filed:
September 8, 2023
Publication date:
December 28, 2023
Applicants:
MITSUBISHI CHEMICAL CORPORATION, KEIO UNIVERSITY
Inventors:
Qi GAO, Ken PRADEL, Naoki YAMAMOTO, Yudai SUZUKI
Abstract: To identify a microorganism causing the development of primary sclerosing cholangitis associated with ulcerative colitis. A Klebsiella pneumoniae strain inducing inflammation in the liver.
Abstract: A method for determining a risk of urothelial carcinoma may be based on the methylation level of DNA. A method for determining a risk of canceration of a urothelial tissue may involve detecting the DNA methylation level of a CpG site of at least one gene selected from TENM3, HOXC4, TLR1, CPVL and PRDM16 in genomic DNA preferably derived from a urothelial cell or a tissue containing the urothelial cell; and determining a risk of canceration of the urothelial tissue from the detected DNA methylation level.
Abstract: The present invention relates to an axon bundle obtained by a method of culturing a nerve cell aggregation having one spheroid and an axon bundle extending from the spheroid wherein the nerve cell aggregation consisting of a plurality of neurons having a cell body and an axon obtained by a method comprising the following step: supplying a culture medium to one first chamber, one second chamber and one channel having the length of at least 1 mm, the width of 100 to 150 ?m and the height of 100 to 200 ?m, which connecting said first chamber and second chamber, wherein said first chamber, second chamber, and channel are contained in one of the modules disposed in a culture plate, seeding the first chamber with a nerve cell derived from a stem cell or a spheroid of primary cultured nerve cells; and culturing said nerve cell, thereby growing an axon bundle from said spheroid and extending them into said channel, wherein the length of the axon bundle obtained is 1 mm or more, and the diameter of the axon bundles
Type:
Application
Filed:
October 28, 2021
Publication date:
December 7, 2023
Applicants:
KEIO UNIVERSITY, Jiksak Bioengineering Inc.