Abstract: A method for producing a diffraction grating is provided. First, a mixture including nematic liquid crystal, dopant, and polymerizable precursor is introduced between two electrically conductive substrates having alignment layers for inducing orientation of the liquid crystal director. A potential difference is applied across the liquid crystal to cause a spontaneous self-assembly of the liquid crystal into an array of convective rolls. Thereafter, the roll structure is stabilized by the creation of a polymeric network through polymerization and/or cross-linking of the polymerizable precursor. The convective roll structure serves as a template for the formation of the polymeric network.

Abstract: A unique class of chiral additive materials is disclosed for use in cholesteric displays that possess a helical twist power substantially independent of temperature. The additives have a solubility and a helical twist power large enough to be used as a single chiral component with little dilution of the physical properties of the nematic liquid crystal host mixture. The chiral additives may be used in combination with non-chiral additives to provide a helical twisting power substantially independent of temperature suitable for cholesteric displays.

Abstract: An optical compensation film for a liquid crystal display is provided wherein the film is a polymer that is capable of producing light induced anisotropy. The film is irradiated with light to form an optical axis or axes.

Abstract: Devices and systems for the detection of ligands comprising at least one receptor and an amplification mechanism comprising a liquid crystalline, where an amplified signal is produced as a result of receptor binding to a ligand are provided. Also provided are methods for the automatic detection of ligands.

Abstract: The present invention provides a compound and process for manufacturing thickened sheet-molding compounds wherein a thermoset molding resin is partially crosslinked by irradiation with high-energy electrons. In this process, the structure of the resin is changed from a viscous liquid to a viscoelastic gel, which acts like a thickened molding compound.

Abstract: A new light modulating material using unidirectionally oriented micro-domains of liquid crystal separated by polymer chains is provided. Liquid crystal/polymer films are produced by a one step production process involving a photopolymerizable monomer mixed with a liquid crystal then exposed to UV light. In one embodiment, force deformations are applied to the films resulting in diffraction efficiencies of more than 95%. In another embodiment, applying a planar force to a thick film that produced a 2 &mgr;m shift of phase retardation in several hundred microseconds when an appropriate field is applied. Use of this invention provides fast response time and a low required driving voltage. The new cell can be used as spatial light modulators for manufacturing information displays, electro-optical devices, telecommunications system, optical data processing, adaptive optics applications, color projection displays and switchable micro-lens optics.

Abstract: A broad class of lyotropic liquid crystals of a non-surfactant nature, the so-called lyotropic chromonic liquid crystals (LCLCs), are alignable with the techniques, in particular, LCLCs can be aligned at a surface as one monomolecular layer as a stack of monomolecular layers. The method for monolayer alignment is based on alternate layer-by-layer adsorption of polyions and dyes from aqueous solutions that have liquid crystalline structure. Using this method, one is able to stack alternate monolayers of dye and polyion while controlling the long-range in-plane orientation of the dye molecules within the plane of each layer. The feature of controlling the alignment of LCLCs enables one to create practical devices from them. For example, alignment of multilayered stacks allows one to use the resulting dried LCLC films in optical devices, for example, as internal polarizers, color filters, optical compensators, band-gap filters, and the like.

Abstract: A polymerizable liquid crystalline monomer is described comprising a polymerizable first terminal group, a central portion, and a second terminal group, wherein the monomer is capable of filament formation. Filaments can form as a result of an isotropic to smectic phase transition and can subsequently be polymerized by photoinitiation, for example.

Abstract: The present invention provides a method of inhibiting the formation of infectious herpes virus particles, particularly infectious herpes simplex virus (HSV) particles, in a host cell. The method involves administering an effective amount of a hydroxylated tolan, particularly a polyhydroxylated tolan, to a herpes virus infected host cell. The present invention also provides a method of treating a herpes virus infection, particularly an HSV infection. The method comprises administering a topical composition comprising a therapeutically effective amount of a hydroxylated tolan to a herpes virus-infected site. The present invention also relates to a topical composition for treating a herpes virus infection selected from the group consisting of an HSV infection, a cytomegalovirus infection, and a varicella zoster virus infection. The present invention also provides a method of treating a subject infected with Neisseria gonorrhea.

Abstract: A liquid crystal display device including a polyimide alignment layer, having a bistable liquid crystal material and a polymer stabilizer in an amount effective to stabilize the liquid crystal the liquid crystal preferably having a low or medium pretilt angle to eliminate undesired states and stripe tendency and to increase hysteresis. The device has a low driving voltage, low power consumption and fast switching.

Abstract: A broad class of lyotropic liquid crystals of a non-surfactant nature, the so-called lyotropic chromonic liquid crystals (LCLCs), are alignable in bulk. LCLCs can be aligned in bulk as a uniform liquid crystalline monodomain within a closed cell. The method for bulk alignment of LCLCs is based on a unidirectional treatment of the aligning substrate such as a polymer layer. The feature of controlling the alignment of LCLCs enables one to create practical devices from them. For example, bulk alignment of LCLCs allows one to use them in detection and amplification of ligands.

Abstract: A broad class of lyotropic liquid crystals of a non-surfactant nature, the so-called lyotropic chromonic liquid crystals (LCLCs), are alignable with the techniques, in particular, LCLCs can be aligned at a surface as one monomolecular layer as a stack of monomolecular layers. The method for monolayer alignment is based on alternate layer-by-layer adsorption of polyions and dyes from aqueous solutions that have liquid crystalline structure. Using this method, one is able to stack alternate monolayers of dye and polyion while controlling the long-range in-plane orientation of the dye molecules within the plane of each layer. The feature of controlling the alignment of LCLCs enables one to create practical devices from them. For example, alignment of multilayered stacks allows one to use the resulting dried LCLC films in optical devices, for example, as internal polarizers, color filters, optical compensators, band-gap filters, and the like.

Abstract: A broad class of lyotropic liquid crystals of a non-surfactant nature, the so-called lyotropic chromonic liquid crystals (LCLCs), are alignable in bulk. LCLCs can be aligned in bulk as a uniform liquid crystalline monodomain within a closed cell. The method for bulk alignment of LCLCs is based on a unidirectional treatment of the aligning substrate such as a polymer layer. The feature of controlling the alignment of LCLCs enables one to create practical devices from them. For example, bulk alignment of LCLCs allows one to use them in detection and amplification of ligands.

Abstract: A broad class of lyotropic liquid crystals of a non-surfactant nature, the so-called lyotropic chromonic liquid crystals (LCLCs), are alignable in bulk. LCLCs can be aligned in bulk as a uniform liquid crystalline monodomain within a closed cell. The method for bulk alignment of LCLCs is based on a unidirectional treatment of the aligning substrate such as a polymer layer. The feature of controlling the alignment of LCLCs enables one to create practical devices from them. For example, bulk alignment of LCLCs allows one to use them in detection and amplification of ligands.

Abstract: A site-specific antibiotic delivery system and related method comprising a fibrin sealant and an antibiotic releasably bound to the fibrin sealant, wherein the antibiotic is delivered in situ and wherein the dose of antibiotic delivered to the organism is sufficient to kill substantially all antibiotic-resistant bacteria present in an infectious focus.

Abstract: A method for generating random numbers includes the steps of providing a liquid crystal cell containing a liquid crystal material, wherein a potential difference is applied across said liquid crystal material to cause a chaotic turbulent flow. The resulting flow or physical result of the liquid crystal material is measured to generate a baseline measurement, and subsequently the at least one physical property is measured again to generate a plurality of reading measurements. Determining the difference between each of the reading measurements and the baseline measurement, and setting bits based on the differences generates a sequence of random numbers. An apparatus for generating random numbers is also disclosed. These truly random numbers may then be used to encrypt data prior to transmission.

Abstract: A dual frequency cholesteric display includes a pair of opposed substrates, wherein one of the substrates has a first plurality of electrodes facing a second plurality of electrodes on the other substrate. A dual frequency bistable cholesteric liquid crystal material is disposed between the substrates, wherein the material and the intersection of the first and second plurality of electrodes forms a plurality of pixels. By selectively applying high and low frequency voltages to the plurality of pixels, the high frequency voltage causes the material to exhibit one texture and the low frequency voltage causes the material to exhibit another texture. By adjusting a voltage amplitude value for each high and low frequency causes each pixel to exhibit a desired reflectance.

Abstract: A driving circuit for a reflective bistable cholesteric liquid crystal display which includes one substrate having a plurality of column or segment electrodes opposed by another substrate having a plurality of row or common electrodes. The intersecting column and row electrodes with the cholesteric material therebetween form a plurality of pixels. The driving circuit selectively applies a voltage to the row and column electrodes to control the appearance of the cholesteric material. In particular, the driving circuit includes at least one common driver coupled to respective common electrodes with each common driver having a first and a second common frame switch with corresponding high or low inputs. The first and second common frame switches are linked to one another by a common frame line.

Abstract: A series of drive schemes are used to apply a single phase of at least one voltage pulse to drive a display with a bistable cholesteric liquid crystal material to a gray scale reflectance. Each drive scheme takes into consideration the initial texture of the cholesteric material and the range of voltages that may be applied between maximum and minimum reflectance of the material. Application of the single phase can be implemented by either time modulation or amplitude modulation.

Abstract: Bistable cholesteric liquid crystal material is disposed between opposed substrates, wherein one of the substrates has a first plurality of electrodes facing a second plurality of electrodes on the other substrate, wherein the intersection of the first and the second plurality of electrodes forms a plurality of pixels. The material is addressed by applying a preparation voltage across the first and second plurality of electrodes and then subsequently applying a selection voltage across the first and second plurality of electrodes. The material is then allowed to relax for a period of time, whereupon the preparation and selection voltages are reapplied. These steps are repeated until the liquid crystal material obtains the desired reflectance.