Abstract: Provided is a novel compound which can germinate seeds of root parasitic plants, more specifically, a compound represented by the formula: wherein R1, R2, R3, R4, and R5 are the same or different and each represents a hydrogen atom, a halogen atom, a lower alkyl group, or a lower alkoxy group, or R1 and R2 are linked together to form a lower alkylenedioxy group, or R1 and R2 together with the adjacent carbon atoms form a benzene ring, or R2 and R3 are linked together to form a lower alkylenedioxy group, or R2 and R3 together with the adjacent carbon atoms form a benzene ring, R6 represents a hydrogen atom or a lower alkyl group, X and Y are the same or different and each represents an oxygen atom and a sulfur atom, and n represents an integer of 0, 1 or 2, and a method for controlling root parasitic plants.

Abstract: The present invention provides an anticancer drug having a Ras function inhibitory action. The present invention provides a Ras function inhibitor comprising a compound represented by the formula (I?): wherein each symbol is as defined in the present specification, or a salt thereof.

Abstract: An embodiment with a dual-stage reflectron is as follows: (1) On the assumption that a reflector has a base potential XA(U) created by uniform electric fields, its design parameters are adjusted so as to cancel the first and second order derivatives at energy E=E0 of a total time of flight T(E), and a second-order focusing position on a central axis at which the potential value becomes zero is determined (Mamyrin solution). (2) A correcting potential XC(U) to be superposed on XA(U), beginning from the second-order focusing position, is calculated so that T(E) of ions reflected in a region deeper than the second-order focusing position will be constant. (3) Voltage values of the reflector electrodes are determined so that a real potential XR(U)=XA(U)+XC(U) is created on the central axis.

Abstract: The present invention provides a prophylactic or therapeutic agent for fracture and bone diseases as well as a bone growth promoting agent containing carbon dioxide as an active ingredient. Further, according to the present invention, an additive or synergistic effect for preventing or treating fracture and bone diseases as well as for promoting bone growth by combining the therapeutic agent of the present invention and a bone absorption inhibitor and/or a bone formation promoter is obtained.

Abstract: Provided is a novel method of producing ethanol by using a cellulose-based biomass as a raw material. In particular, provided is a novel method of producing ethanol by which ethanol can be effectively produced in the presence of a substance having an inhibitory action on fermentation of ethanol. Ethanol can be effectively produced by using a microorganism engineered to suppress the expression of at least one kind of phosphatase among the phosphatases intrinsically possessed by the microorganism, even under a condition where a substance that has heretofore been believed to have a fermentation inhibitory action, specifically, a weakly acidic substance and/or a furan compound are/is incorporated.

Abstract: Provided is an information encoding method and a holographic memory device which increase the amount of information per page of a holographic memory and reduce the bit error rate to ensure a larger multiplexing number. The holographic memory information encoding method expresses information of signal page data in a holographic memory as a multi-stage data using different resolution by block coding, and superimposes each data on a single page of signal page data. The multi-stage data using different resolution is realized by light amplitude data and phase data. The amplitude data is divided by area through block coding. When n odd-numbered ON bits exist in a divided area of the phase data, a phase of 2?s/n (where n and s are natural numbers) is imparted as s-th phase information to one value of binary data, and the same phase is imparted to the other value of binary data.

Abstract: A preparation process for a cyclic conjugated polymer, includes the steps of deprotonating a monohalogenated cyclic conjugated compound of a 5- to 7-membered ring using a deprotonation catalyst comprising secondary amine represented by R1NHR2 (R1 and R2 are the same or different and are each a branched or cyclic alkyl group of 1 to 15 carbon atoms or a phenyl group) and a Grignard reagent represented by R3MgX (X is a halogen atom selected from chlorine, bromine and iodine, and R3 is a straight-chain or branched alkyl group of 1 to 6 carbon atoms) and polymerizing the deprotonated monohalogenated cyclic conjugated compound.

Abstract: An image diagnostic processing device includes peripheral region specifying means which specifies a peripheral region connecting to an abnormal candidate region included in an image representing the inside of a subject, and judging means which judges whether the abnormal candidate region is an anatomic abnormal region or not, based on a first feature quantity of the abnormal candidate region and a second feature quantity of the peripheral region.

Abstract: A distribution analysis device analyzes a distribution of a field having a property satisfying the Laplace equation, and includes: an obtainment unit that obtains measurement data indicating the distribution of the field measured through a sensor sensing area, the sensor sensing area being an area that moves in a measurement area where the distribution of the field is measured and being an area in which the field is sensed as an aggregate; and a calculation unit that calculates analysis data indicating the distribution of the field with a higher resolution than the measurement data, using an arithmetic expression that is obtained by deriving a solution of the Laplace equation using a boundary condition that an integral of the solution of the Laplace equation in a finite interval corresponding to a size of the sensor sensing area matches the measurement data.

Abstract: Provided is a screening method for a more effective Ras inhibitor. Further provided are amino acid residues at a site important for an interaction with a Ras inhibitor in a Ras polypeptide. By confirming a difference between structural information on the Ras polypeptide by NMR and structural information between a complex of the Ras polypeptide and a seed compound by NMR, a more effective lead compound than the seed compound can be selected. As a result of analysis based on the structural information on the Ras polypeptide by NMR, the amino acid residues capable of interacting with a Ras inhibitor candidate (a) are K5, E37, D38, S39, L56, E63, Y64, A66, M67, Q70, Y71, R73, and T74 with reference to an amino acid sequence set forth in SEQ ID NO: 1.

Abstract: Provided is a method for manufacturing a three-dimensional molded model that can reproduce the feel of an organ. A three-dimensional shape of a body site subject to molding is extracted from brightness information of two-dimensional data obtained from medical diagnostic devices, and three-dimensional molding data of the body site and the internal structure site thereof is created. The three-dimensional shape data is edited using a modeling function. Respective touch equivalent parameter tables are created. The material type and the formulation ratio of the modeling material used for molding each body site and internal structural site are defined, and added to the touch equivalent parameter tables. Primitive shape data is generated from the parameters of the touch equivalent parameter tables, and a Boolean operation is performed on the body site data and internal structure site data as well as on the primitive shape data. Molding is performed using the defined materials.

Abstract: An antitumor agent comprising carbon dioxide as an active ingredient of the present invention can reduce the tumor volume or eradicate the tumor of a patient who is difficult to take a surgical therapy, a chemotherapy, a radiation therapy or an immunotherapy. The antitumor agent comprising carbon dioxide as an active ingredient of the present invention is useful because the agent enables (1) the reduction in size or elimination of a tumor, (2) the suppression of tumor metastasis and also (3) the reduction in volume or elimination of a tumor at a part different from the part where carbon dioxide is transdermally absorbed by the transdermal absorption of carbon dioxide through the skin near the tumor or the skin far from the tumor.

Abstract: Provided is a radiotherapeutic agent, including a composite particle, which is obtained by binding a molecule that specifically recognizes a target to a substrate particle including titanium peroxide, and which generates reactive oxygen through irradiation with a radiation. Further, because the radiotherapeutic agent contains the molecule that specifically recognizes a target, the radiotherapeutic agent has a function of accumulating in the target. The radiotherapeutic agent is capable of enhancing effects of radiotherapy, and is capable of reducing side effects on a living body to efficiently attack the target.

Abstract: Disclosed are method for treating diabetes, a protein for treatment of diabetes, and pharmaceutical composition comprising the same. The protein is human mature chemerin, which can be used to treat diabetes, in particular type 2 diabetes, inter alia to treat diabetes in a patient who is concurrently administered with insulin.

Abstract: The present invention provides a method for producing a cellulose degradable yeast, comprising the step of co-introducing genes coding for at least two cellulose-degrading enzymes into a yeast host via integration with a yeast ? sequence. According to the invention, a yeast having an improved cellulose degradation ability are provided.

Abstract: A surface analyzer 1 includes: a sample stage 6 for placing a sample 5; a source for generating multicharged ions 3 for irradiating a beam 4 of multicharged ions having a valence of 15 or higher to the sample 5 placed on the sample stage 6; a mass analyzer 8 for detecting secondary ions 7 generated as a result of irradiating the beam of multicharged ions 4 to the sample 5; a secondary electron detector 10 for detecting secondary electrons 9 generated as a result of irradiating the beam of multicharged ions 4 to the sample 5; and a controller of mass analyzer 12 for generating analysis start signals in response to the secondary electron signals received, and transmitting the start signals to the mass analyzer. The surface analyzer 1 enables high-quality analysis of the surface of the sample in short time by using the multicharged ions.

Abstract: For minimally-invasive therapy for spinal canal stenosis, a therapeutic device capable of stationing an interspinous process spacer without the need of large skin incision or ligamentous tissue incision and also without the need of detaching of the paraspinal muscle from the spine. The interspinous process spacer includes a conoid screw region (2) to be screwed into a processus spinosus interspace; a spacer region (3) in the longitudinal direction of the screw region (2); head region (4) capable of free interlocking with a tool arbitrarily; and through-hole (5) passing through the axial centers of screw region (2), spacer region (3) and head region (4). The processus spinosus interspace is enlarged by screwing of the screw region (2) into the processus spinosus interspace. The spacer region (3) is pinched upon passing of the screw region (2) through the processus spinosus interspace to attain enlarging and fixing of adjacent processus spinosus interspaces.

Abstract: An apparatus is provided for classifying targets into a known-object group and an unknown-object group. The apparatus includes a speech/image data storage unit configured to store a spoken sound of a name of an object and an image of the object; a unit configured to calculate a speech confidence level of a speech for the name of the object with reference to a spoken sound of a name of a known object; a unit configured to calculate an image confidence level of an image of an object with respect to an image of a known object; and a unit configured to compare an evaluation value, which is obtained by combining the speech confidence level and image confidence level, with a threshold value, and classify a target object into an object group determined according to whether the spoken sound of the name and the image are known or unknown.

Abstract: Provided is a semi-permeable composite membrane which exhibits both high durability and high solute-removal and water-permeation performances. The semi-permeable composite membrane is formed from a porous support membrane and a polymer membrane. The polymer membrane is formed of at least one type of polymer (a) with a positive charge in the repeating unit and at least one type of polymer (b) with a negative charge in the repeating unit and has a crosslinked structure formed by siloxane bonds between the polymer (a) and the polymer (a), between the polymer (a) and the polymer (b), and/or between the polymer (b) and the polymer (b).

Abstract: Provided is a novel compound which can germinate seeds of root parasitic plants, more specifically, a compound represented by the formula: wherein R1, R2, R3, R4, and R5 are the same or different and each represents a hydrogen atom, a halogen atom, a lower alkyl group, or a lower alkoxy group, or R1 and R2 are linked together to form a lower alkylenedioxy group, or R1 and R2 together with the adjacent carbon atoms form a benzene ring, or R2 and R3 are linked together to form a lower alkylenedioxy group, or R2 and R3 together with the adjacent carbon atoms form a benzene ring, R6 represents a hydrogen atom or a lower alkyl group, X and Y are the same or different and each represents an oxygen atom and a sulfur atom, and n represents an integer of 0, 1 or 2, and a method for controlling root parasitic plants.