Patents Assigned to Kyoto Daiichi Kagaku Co., Ltd.
  • Patent number: 7393502
    Abstract: A test device 1 for analyzing a specific component in a test solution with a reagent by allowing the solution introduced via a feed opening 4 to react with the reagent maintained in a predetermined position in a capillary tube 3 having the opening 4 and an air outlet 5. The tube is provided with two hydrophilic regions 31, 33 and a hydrophobic region 32. The region 31 transfers the solution from the opening 4 to the reagent. The region 33 is delimited to a predetermined area maintaining the reagent. The region 32 separates the region 31 from the region 33. The reagent and the solution are applied in predetermined amounts to the region 33. A measuring device need not previously measure the solution. The device is useful as an analytical device for rapid and easy analysis, and can be produced in a less number of steps because the reagent can be fixed by merely applying it onto a predetermined position.
    Type: Grant
    Filed: August 1, 2002
    Date of Patent: July 1, 2008
    Assignee: Kyoto Daiichi Kagaku Co., Ltd.
    Inventors: Akio Okubo, Atsuko Katayama, Yoshiyuki Tanaka, Yoshihiko Higuchi, Masufumi Koike
  • Patent number: 6827829
    Abstract: The present invention is to provide a concentration measuring apparatus, a test strip for the concentration measuring apparatus, a biosensor system and a method for forming terminals of the test strip, whereby a component to be measured can be measured by the test strip fit to the target component to be measured. A type judgement electrode is provided separately from a positive electrode and a negative electrode in a measuring apparatus so as to judge the type of a set test strip with the measuring apparatus. Thus only when a test strip matching the measuring apparatus is set, the type judgement electrode is electrically connected to a terminal of the set test strip, enabling the measuring apparatus to measure a component to be measured in a liquid test sample.
    Type: Grant
    Filed: March 6, 2003
    Date of Patent: December 7, 2004
    Assignees: Kyoto Daiichi Kagaku Co., Ltd., Matsushita Electric Industrial Co., Ltd.
    Inventors: Shoji Kawanaka, Yoshinobu Tokuno, Kohei Ishida
  • Patent number: 6797520
    Abstract: A composition capable of showing a color change sufficient for indicating the presence and/or concentration of a protein in a protein-containing liquid sample by contacting with the sample, comprising: indium or an indium compound, and a dye or pigment capable of forming a complex with indium.
    Type: Grant
    Filed: October 2, 2001
    Date of Patent: September 28, 2004
    Assignee: Kyoto Daiichi Kagaku Co., Ltd.
    Inventor: Hideko Kosaka
  • Patent number: 6673632
    Abstract: The present invention provides a method by which UTI concentration can be measured easily with high precision and good reproducibility. The measurement is performed by adding free anti-UTI antibodies to a sample and measuring the degree of the resulting agglutination, for example, from the change in absorbance. As shown in FIG. 3, the UTI concentration and the degree of the agglutination (i.e. the change in absorbance) are correlated. The absorbance can be measured by using a general spectrophotometer, preferably at a wavelength of 300 to 400 nm. Polyethylene glycol is preferably added to the reaction solution as an agglutination accelerator. The polyethylene glycol preferably has an average molecular weight of 2,000 to 20,000, and the concentration of polyethylene glycol in the reaction solution is preferably in the range of 2 to 10 weight %.
    Type: Grant
    Filed: August 14, 1998
    Date of Patent: January 6, 2004
    Assignee: Kyoto Daiichi Kagaku Co., Ltd.
    Inventor: Kyouichi Ohshiro
  • Patent number: 6612986
    Abstract: A dispersed-type testing/measuring system provides for example a simplified terminal unit to be installed at a patient's home. The dispersed-type testing/measuring system has a central controlling unit 20 and a plurality of terminal units 30 each accessible to the central controlling unit via a communication line 15. Each terminal unit 30 includes a crude data collecting portion 40, and a data transmitting means 45 for sending the data collected by the crude data collecting portion 40 to the central controlling unit 20. The central controlling unit 20 includes a measurement data calculating means 210 for generating measurement data by making calculation on the crude data sent from each terminal unit 30.
    Type: Grant
    Filed: March 7, 2001
    Date of Patent: September 2, 2003
    Assignee: Kyoto Daiichi Kagaku Co., Ltd.
    Inventors: Shigeru Doi, Harumi Uenoyama, Yoshinori Yamaguchi
  • Publication number: 20030150724
    Abstract: The present invention is to provide a concentration measuring apparatus, a test strip for the concentration measuring apparatus, a biosensor system and a method for forming terminals of the test strip, whereby a component to be measured can be measured by the test strip fit to the target component to be measured.
    Type: Application
    Filed: March 6, 2003
    Publication date: August 14, 2003
    Applicant: Kyoto Daiichi Kagaku Co., Ltd.
    Inventors: Shoji Kawanaka, Yoshinobu Tokuno, Kohei Ishida
  • Patent number: 6599406
    Abstract: The present invention is to provide a concentration measuring apparatus, a test strip for the concentration measuring apparatus, a biosensor system and a method for forming terminals of the test strip, whereby a component to be measured can be measured by the test strip fit to the target component to be measured. A type judgement electrode is provided separately from a positive electrode and a negative electrode in a measuring apparatus so as to judge the type of a set test strip with the measuring apparatus. Thus only when a test strip matching the measuring apparatus is set, the type judgement electrode is electrically connected to a terminal of the set test strip, enabling the measuring apparatus to measure a component to be measured in a liquid test sample.
    Type: Grant
    Filed: January 21, 2000
    Date of Patent: July 29, 2003
    Assignees: Kyoto Daiichi Kagaku Co., Ltd., Matsushita Electric Industrial Co., Ltd.
    Inventors: Shoji Kawanaka, Yoshinobu Tokuno, Kohei Ishida
  • Patent number: 6582659
    Abstract: A clinical test apparatus includes a reaction table (1) for placing a test piece thereon for reaction of the test piece with an analyte at a predetermined temperature to perform analysis. The clinical test apparatus includes a primary coil (3) fixed, as molded and sealed in resin, on a base facing the reverse surface of the reaction table (1) and supplied with alternating power, a secondary coil (4) mounted, as molded and sealed in resin, on the reverse surface of the reaction table (1) in facing relation to the primary coil (3) for inducing an electromotive force due to the alternating power supplied to the primary coil and a heater (5) built in the reaction table (1) for generating heat due to the electromotive force induced in the secondary coil.
    Type: Grant
    Filed: December 10, 1999
    Date of Patent: June 24, 2003
    Assignee: Kyoto Daiichi Kagaku Co., Ltd.
    Inventor: Yasuhito Murata
  • Patent number: 6540962
    Abstract: A test device 1 for analyzing a specific component in a test solution with a reagent by allowing the solution introduced via a feed opening 4 to react with the reagent maintained in a predetermined position in a capillary tube 3 having the opening 4 and an air outlet 5. The tube is provided with two hydrophilic regions 31,33 and a hydrophobic region 32. The region 31 transfers the solution from the opening 4 to the reagent. The region 33 is delimited to a predetermined area maintaining the reagent. The region 32 separates the region 31 from the region 33. The reagent and the solution are applied in predetermined amounts to the region 33. A measuring device need not previously measure the solution. The device is useful as an analytical device for rapid and easy analysis, and can be produced in a less number of steps because the reagent can be fixed by merely applying it onto a predetermined position.
    Type: Grant
    Filed: December 9, 1999
    Date of Patent: April 1, 2003
    Assignee: Kyoto Daiichi Kagaku Co., Ltd.
    Inventors: Akio Okubo, Atsuko Katayama, Yoshiyuki Tanaka, Yoshihiko Higuchi, Masufumi Koike
  • Publication number: 20030031593
    Abstract: A test device 1 for analyzing a specific component in a test solution with a reagent by allowing the solution introduced via a feed opening 4 to react with the reagent maintained in a predetermined position in a capillary tube 3 having the opening 4 and an air outlet 5. The tube is provided with two hydrophilic regions 31, 33 and a hydrophobic region 32. The region 31 transfers the solution from the opening 4 to the reagent. The region 33 is delimited to a predetermined area maintaining the reagent. The region 32 separates the region 31 from the region 33. The reagent and the solution are applied in predetermined amounts to the region 33. A measuring device need not previously measure the solution. The device is useful as an analytical device for rapid and easy analysis, and can be produced in a less number of steps because the reagent can be fixed by merely applying it onto a predetermined position.
    Type: Application
    Filed: August 1, 2002
    Publication date: February 13, 2003
    Applicant: Kyoto Daiichi Kagaku Co., Ltd.
    Inventors: Akio Okubo, Atsuko Katayama, Yoshiyuki Tanaka, Yoshihiko Higuchi, Masufumi Koike
  • Patent number: 6514720
    Abstract: A highly reliable method of measuring an analyte in a sample using a redox reaction. In this method, a tetrazolium compound is added to a sample prior to the redox reaction so as to eliminate the influence of any reducing substance in the sample, then a reducing substance or an oxidizing substance derived from the analyte is formed, the quantity of the formed substance derived from the analyte is measured by the redox reaction, and the quantity of the analyte is determined from the quantity of the formed substance derived from the analyte. As the tetrazolium compound, for example, 2-(4-iodophenyl)-3-(2,4-dinitrophenyl)-5-(2,4-disulfophenyl)-2H-tetrazolium salt can be used.
    Type: Grant
    Filed: September 5, 2001
    Date of Patent: February 4, 2003
    Assignee: Kyoto Daiichi Kagaku Co., Ltd.
    Inventors: Tsuguki Komori, Satoshi Yonehara
  • Patent number: 6455865
    Abstract: A test piece analyzing apparatus is provided which includes a releasably fixed absorbent member, a horizontally reciprocative pinching mechanism for simultaneously transferring a plurality of test pieces in a transfer direction, and an optical analyzing assembly provided with a primary illuminator and a secondary illuminator. The second illuminator serves to illuminate the bottom surface of the test piece.
    Type: Grant
    Filed: April 30, 2001
    Date of Patent: September 24, 2002
    Assignee: Kyoto Daiichi Kagaku Co., Ltd.
    Inventor: Kouji Egawa
  • Patent number: 6423490
    Abstract: A method for measuring the presence of polynucleotide in a sample, comprising the steps of: (1) preparing a sample, an agglutinative agent and an agglutination promoter capable of binding to polynucleotide; (2) mixing said sample, said agent and said promoter; and (3) measuring the degree of agglutination of the agent.
    Type: Grant
    Filed: October 22, 1997
    Date of Patent: July 23, 2002
    Assignee: Kyoto Daiichi Kagaku Co., Ltd.
    Inventor: Toshio Takama
  • Patent number: 6407403
    Abstract: A test piece analyzing apparatus is provided which includes a releasably fixed absorbent member, a horizontally reciprocative pinching mechanism for simultaneously transferring a plurality of test pieces in a transfer direction, and an optical analyzing assembly provided with a primary illuminator and a secondary illuminator. The second illuminator serves to illuminate the bottom surface of the test piece.
    Type: Grant
    Filed: April 30, 2001
    Date of Patent: June 18, 2002
    Assignee: Kyoto Daiichi Kagaku Co., Ltd.
    Inventor: Atsushi Murakami
  • Patent number: 6404492
    Abstract: An acousto-optic tunable filter 4 including: an acousto-optic crystal 41; an acoustic wave driver 42; and a piezoelectric transducer 43, is provided in front of a light source section 2 including a plurality of light sources 2A, 2B, . . . 2N having different wavelength characteristics. The frequency of RF generated by the acoustic wave driver 42 is varied in accordance with a desired wavelength. Thus, the light having the desired wavelength is incident on a converging lens 5 as plus and minus first-order light beams, and the light having wavelengths other than the desired wavelength is incident on a converging lens 5 as a zero-order light beam. The converging lens 5 converges the plus and minus first-order light beams and the zero-order light beams at positions different from each other. A selector 6 having openings located at the positions onto which the plus and first-order light beams are converged is provided in front of the converging lens 5.
    Type: Grant
    Filed: July 7, 1998
    Date of Patent: June 11, 2002
    Assignee: Kyoto Daiichi Kagaku Co., Ltd.
    Inventors: Kexin Xu, Keiichi Fukada
  • Patent number: 6381489
    Abstract: A measurement condition setting fixture 2 is secured to a measurement site 1 of a living body prior to the measurement. At the time of measurement, a light irradiation section 3 and a light receiving section 5 of a measuring optical system are respectively attached and secured to a light irradiation section securing section 10 and a light receiving section securing section 11 of the measurement condition setting fixture 2. Thus, the measurement site 1 and the measuring optical system are secured to each other, and desirable measurement conditions can be realized. Moreover, the measurement conditions can be maintained throughout the measurement. After the measurement is completed, the measurement site 1 can be removed from the measuring optical system by detaching the light irradiation section 3 and the light receiving section 5 from the light irradiation section securing section 10 and the light receiving section securing section 11.
    Type: Grant
    Filed: July 7, 1998
    Date of Patent: April 30, 2002
    Assignee: Kyoto Daiichi Kagaku Co., Ltd.
    Inventor: Emi Ashibe
  • Patent number: 6377896
    Abstract: A measuring method for determination of the content of a substance in a specimen on the basis of the value of a physical property measured with the specimen in which the determination is influenced by another substance coexisting with the object substance in the specimen, characterized in that: the value of the physical property measured with the specimen with a known content Ht of the coexisting substance is corrected to a value Vc of the physical property calculated with a standard content value Hts as the content Ht of the coexisting substance on the basis of a correction table showing the relationship between the contents Ht of the coexisting substance and set values V of said physical property for the respective key contents of the object substance. The measuring method permits instantaneous determination with high precision of the content of a substance for which no calibration curve can be prepared because of the effects of a coexisting substance.
    Type: Grant
    Filed: January 5, 1999
    Date of Patent: April 23, 2002
    Assignee: Kyoto Daiichi Kagaku Co., Ltd.
    Inventors: Yoshiharu Sato, Hisashi Okuda
  • Publication number: 20020037591
    Abstract: A composition capable of showing a color change sufficient for indicating the presence and/or concentration of a protein in a protein-containing liquid sample by contacting with the sample, comprising: indium or an indium compound, and a dye or pigment capable of forming a complex with indium.
    Type: Application
    Filed: October 2, 2001
    Publication date: March 28, 2002
    Applicant: KYOTO DAIICHI KAGAKU CO., LTD.
    Inventor: Hideko Kosaka
  • Patent number: 6352835
    Abstract: A highly reliable method of measuring an analyte in a sample using a redox reaction. In this method, a tetrazolium compound is added to a sample prior to the redox reaction so as to eliminate the influence of any reducing substance in the sample, then a reducing substance or an oxidizing substance derived from the analyte is formed, the quantity of the formed substance derived from the analyte is measured by the redox reaction, and the quantity of the analyte is determined from the quantity of the formed substance derived from the analyte. As the tetrazolium compound, for example, 2-(4-iodophenyl)-3-(2,4-dinitrophenyl)-5-(2,4-disulfophenyl)-2H-tetrazolium salt can be used.
    Type: Grant
    Filed: November 15, 1999
    Date of Patent: March 5, 2002
    Assignee: Kyoto Daiichi Kagaku Co. Ltd.
    Inventors: Tsuguki Komori, Satoshi Yonehara
  • Publication number: 20020025546
    Abstract: A highly reliable method of measuring an analyte in a sample using a redox reaction. In this method, a tetrazolium compound is added to a sample prior to the redox reaction so as to eliminate the influence of any reducing substance in the sample, then a reducing substance or an oxidizing substance derived from the analyte is formed, the quantity of the formed substance derived from the analyte is measured by the redox reaction, and the quantity of the analyte is determined from the quantity of the formed substance derived from the analyte. As the tetrazolium compound, for example, 2-(4-iodophenyl)-3-(2,4-dinitrophenyl)-5-(2,4-disulfophenyl)-2H-tetrazolium salt can be used.
    Type: Application
    Filed: September 5, 2001
    Publication date: February 28, 2002
    Applicant: Kyoto Daiichi Kagaku Co., Ltd.
    Inventors: Tsuguki Komori, Satoshi Yonehara