Abstract: A biosensor which electrochemically detects a material which relates to a reaction of a specific compound in a liquid sample with a biologically active substance or its related substance, in which the biologically active material or an optionally used mediator is placed at a part which is remote from a position of an electrode which acts as electrochemical detector means, and optionally the biological active material or the mediator is covered with a polymer layer.

Abstract: A multilayer analytical element for assaying fructosamine, having a liquid-impermeable support, a buffer-containing layer which contains a buffer having pH of 8 to 12 formed on the support, a tetrazolium salt containing layer which is formed on the buffer-containing layer and, optionally, an intermediate layer interposed between the buffer-containing layer and the tetrazolium salt-containing layer to prevent contact of these two layers, which element assays fructosamine in a short time with good accuracy.

Abstract: A biosensor for electrochemically detecting an electrochemically active material generated by a reaction of a compound to be analyzed in a liquid sample and at least one compound which specifically reacts with the compound to be analyzed, in which a working electrode has at least two electrode parts and the supplied liquid sample contacts the electrode parts successively at an interval, and with which, the electrochemically active material and the compound to be analyzed are quantitatively analyzed separately.

Abstract: A biosensor which electrochemically detects a material which relates to a reaction of a specific compound in a liquid sample with a biologically active substance or its related substance, in which the biologically active material or an optionally used mediator is placed at a part which is remote from a position of an electrode which acts as electrochemical detector means, and optionally the biological active material or the mediator is covered with a polymer layer.

Abstract: A color test strip for detecting predetermined substances which carries on a support at least one coloring pad and at least one pad for. The correction pad having a pH which is adjusted in relation to pH of the coloring pad. The color test strip can avoid false positive and false negative results.

Abstract: A device for colorimetric assay of at least one component in a liquid sample, which device comprises a support, a reagent layer formed on a part of one surface of the support and a sample-receiving layer which covers at least a part of the reagent layer and at least a part of the support surface, with which the timing of application of a sample on the device is automatically detected with accuracy.

Abstract: There is provided a method for the determination of a glucose concentration in a whole blood utilizing a biosensor. A correction of the measured glucose concentration for dilution error introduced by the solid component of blood cells is calculated based on the change in glucose concentration measured before and after significant glucose has diffused from blood cells into the buffer used to dilute the sample. Thus, the need to centrifuge blood samples to obtain a cell-free serum sample for glucose determination is eliminated.

Abstract: An automatic sample analyzer comprising, a plurality of sticks which have a plurality of reagent portions corresponding to different examination items so as to be divided into a plurality of groups of sticks by combinations of the examination items, a plurality of cassettes each having an outlet and a discriminatory mark, the discriminatory mark corresponding to one of the group of the sticks so as to accommodate the one of the group of the sticks, a removal device for automatically taking a desired one of the sticks of the cassettes by using a single removal mechanism.

Abstract: A sensor 13 is inserted into a connector 14. A constant voltage required to obtain a response current is applied across the connector 14 by a voltage applying source 15 at timings required. A response current of the sensor 13 inserted into the connector 14 is converted into a voltage by a current-to-voltage converter 16, and the amount thereof is determined by a microcomputer, the analysis results being displayed onto a display unit.

Abstract: A device for colorimetric assay of at least one component in a liquid sample, which device comprises a support having a through hole with an area of from 3 to 80 mm.sup.2, a transparent porous film which is provided on the support to cover the hole, a reagent layer provided on a surface of the porous film which is not contacted to the support, and a sample-holding layer which covers the reagent layer and a part of a surface of the support, whereby an amount or concentration of at least one component in the liquid sample may be easily and accurately measured.

Abstract: An agent composition for detecting a redox reaction comprising a redox reagent system, iodic acid or an iodate, and a monovalent thallium compound, which suppresses adverse influence of liberated iodine and provides accurate diagnosis results.

Abstract: There is provided a method for the determination of a glucose concentration in a whole blood utilizing a biosensor. A correction of the measured glucose concentration for dilution error introduced by the solid component of blood cells is calculated based on the change in glucose concentration measured before and after significant glucose has diffused from blood cells into the buffer used to dilute the sample. Thus, the need to centrifuge blood samples to obtain a cell-free serum sample for glucose determination is eliminated.

Abstract: An analyzng device comprises a plate holding table, a shifting mechanism for shifting the plate holding table, bar code reading sensors, and a detecting unit for detecting the signals based on the drops of the solutions in the plate set on the plate holding table located in the plate measurement position. When the data of the bar code read by the bar code reading sensor is not fit for a predetermined measurement condition, the plate holding table is shifted to the plate exhausting position. On the other hand, when the data of the bar code is fit for the predetermined measurement condition, the plate holding table is shifted to the solution pipetting position and when the pipetting of the solutions is finished, the plate holding table is further shifted to the mesurement position. When the concentration of substance in the test solution is completed by the detecting unit, the plate holding table is shifted to the plate exhausting position.