Abstract: A circular resonator, and an optical modulator and an optical element comprising same. The circular resonator includes a first material, formed in a circular shape, including a plurality of nano holes and having a thermo-optic coefficient varying at a predetermined ratio according to temperature, and a second material having a thermo-optic coefficient varying in a direction opposite to the direction of change of the thermo-optic coefficient of the first material depending on temperature, the second material being filled in the plurality of nano holes, wherein an interval between the plurality of nano holes is formed at a pitch shorter than the wavelength of incident light.

Abstract: The present disclosure relates to an optoelectronic device based on a dual micro-cavity structure, and more particularly, to a technology that simultaneously realizes the high Q factors of the three primary colors in an optoelectronic device based on a dual micro-cavity structure. The optoelectronic device according to one embodiment of the present disclosure is applied to a self-emissive device, and includes a first reflector layer, an active cavity layer formed on the first reflector layer, a second reflector layer formed on the active cavity layer, an external cavity layer formed on the second reflector layer, a third reflector layer formed on the external cavity layer, and a passivation layer formed on the third reflector layer, wherein a first micro-cavity corresponding to the first and second reflector layers and a second micro-cavity corresponding to the second and third reflector layers may be generated.

Abstract: The present invention relates to a polysubstituted imidazolo[4,5-c][1,2]thiazine derivative and a use of an agent comprising same as an active agent, which is useful for infectious diseases associated with vascular inflammation caused by HMGB1 protein activity. It has been found that the polysubstituted imidazolo[4,5-c][1,2]thiazine derivative of the present invention increases the sepsis survival rate as a result of searching for antiseptic effects through CLP-induced sepsis animal experiments. Accordingly, the agent comprising the polysubstituted imidazolo[4,5-c][1,2]thiazine derivative or a pharmaceutically acceptable salt thereof as an active agent may be advantageously used as a therapeutic agent for infectious diseases and vascular inflammatory diseases including sepsis caused by HMGB1 protein activity.

Abstract: The present invention relates to a composition, for prevention or treatment of cancer diseases, comprising CD8+ T cells activated by CD4+ T cell-derived extracellular vesicles as an active ingredient. It was found that the secretion of extracellular vesicles from cytokine-activated CD4+ T cells increases and the extracellular vesicles enhance proliferation and activity of CD8+ T cells to induce the death of cancer cells, thereby augmenting an anticancer effect. Thus, the present invention provides the CD8+ T cells activated by CD4+ T cell-derived extracellular vesicles as a pharmaceutical agent or an immunotherapeutic agent for cancer diseases, and a method for activating CD8+ T cells by using CD4+ T cell-derived extracellular vesicles to prepare CD8+ T cells showing excellent anticancer activity as described above.

Abstract: The present invention relates to a composition containing IL-2 or an expression promoter or activator thereof as an active ingredient for prevention or treatment of cancer disease. In the present invention, it was discovered that when treating cancer cells with IL-2, an anticancer effect was enhanced by inhibiting the secretion of cancer cell-derived exosomes and the expression of PD-L1 inducing immune escape of T cells. IL-2 was also discovered to effectuate the anticancer effect directly on cancer cells compared to conventional techniques exhibiting an immune anticancer effect by activating cytotoxic T cells. Thus, IL-2 or an expression promoter or activator thereof can be advantageously used in a composition for prevention or treatment of cancer diseases.

Abstract: The present invention relates to a wild-type-derived introgression line of a tomato in which the expression of BC2.1 is inhibited and the amount of beta-carotene or lutein is increased; and a transgenic tomato.

Abstract: Disclosed is a ZnO/carbon allotrope composite for a formaldehyde sensor. The ZnO/carbon allotrope composite for a formaldehyde sensor comprising a substrate, a conductive metal coating layer formed on the substrate, a ZnO seed layer formed on the coating layer, ZnO nanorods grown from the ZnO seed layer, and a carbon allotrope layer formed on and overlapping with the nanorods. Also disclosed is a method for preparing a ZnO/carbon allotrope composite for a formaldehyde sensor. The method includes depositing a conductive metal coating layer on a substrate, sputtering Zn on the conductive metal coating layer to form a ZnO layer, followed by annealing to form ZnO seeds in the ZnO layer, growing ZnO nanorods from the ZnO seeds; and coating a carbon allotrope on the ZnO nanorods to form a carbon allotrope layer overlapping with the nanorods.

Abstract: The present invention relates to a multi-band image capturing apparatus and method for capturing multi-band images, including visible and infrared images, by using a light adjustment filter, the apparatus comprising: a camera unit for acquiring multi-band images including visible and infrared images; a lighting unit for emitting infrared rays; an optical filter unit which includes a hot mirror filter region and an infrared transmission filter region, and which selectively transmits visible light therethrough by moving and arranging the hot mirror filter region onto an optical path or transmits infrared rays therethrough by moving and arranging the infrared transmission filter region onto the optical path; and a light adjustment control unit for controlling the camera unit, the lighting unit and the optical filter unit, wherein the light adjustment control unit determines a light level on the basis of the light intensity of infrared rays in an photography environment so as to control the lighting unit so that

Abstract: The present invention relates to a pharmaceutical composition for preventing or treating neurodegenerative diseases comprising a COX2 acetylating agent as an active ingredient and, more particularly, to a pharmaceutical composition for preventing or treating neurodegenerative diseases comprising, as an active ingredient, a COX2 acetylating agent which exhibits an effect of inhibiting the deposition of amyloid-? in brain neurons, reducing excessive neuroinflammatory responses, and increasing the phagocytosis of amyloid-? in microglial cells. The pharmaceutical composition for preventing or treating neurodegenerative diseases comprising the COX2 acetylating agent as an active ingredient has the effects of alleviating neuroinflammation by promoting COX2 acetylation in neurons and secreting specialized pro-resolving mediators (SPMs) and thus, can be very useful in the development of a preventive or therapeutic agent for neurodegenerative diseases.

Abstract: The present invention relates to a method for preparing a solid-state photonic crystal IPN composite functionalized with an enzyme, a photonic crystal IPN composite prepared by the method, and a biosensor using the photonic crystal IPN composite. The method of the present invention includes (1) mixing a nonreactive chiral dopant with a reactive nematic mesogen, curing the mixture, and removing the chiral dopant while maintaining a helical structure, to form a solid-state helical photonic crystal structure, (2) infiltrating a PAA hydrogel into the internal space of the photonic crystal structure, followed by curing to form an IPN-structured composite, and (3) immobilizing an enzyme in the IPN-structured composite. The PAA hydrogel is infiltrated into the solid-state helical photonic crystal structure and the enzyme is immobilized such that a pH change caused by the enzymatic reaction induces shrinkage and expansion of the PAA hydrogel, leading to a color change.

Abstract: The present invention relates to a photo-charging energy storage device, and has been made in an effort to provide a photo-charging energy storage device which is capable of self-charging by combining a solar cell and a supercapacitor and used as a power source of an IoTs sensor. The resulting photo-charging energy storage device according to the present invention includes: a solar cell; a conductive connector electrically connected to the solar cell, and combined with the solar cell; and a supercapacitor combined with the conductive connector, and charged with the solar cell via an electrical connection with the solar cell through the conductive connector.

Abstract: A holographic printing system according to an embodiment of the present disclosure is disclosed. The system may include: a light source; a geometrical phase holographic element having a phase retardation of ?/4; and an optical member for copying and printing a wavefront through self-interference of light transmitted through the geometrical phase holographic element. According to an embodiment, the light source, the geometrical phase holographic element, and the optical member may be disposed in a line. According to an embodiment, the geometrical phase holographic element and the optical member may be disposed with a predetermined distance therebetween, and the predetermined distance may be a distance that enables self-interference of light transmitted through the geometrical phase holographic element.

Abstract: Disclosed are a system and method for analyzing a stool image, which derive the state of the large intestine of a user by analyzing a stool image by using a pre-trained deep learning model. The system for analyzing a stool image may include an input unit configured to receive stool images of a user, a data set generation unit configured to generate a data set by grouping the stool images in chronological order, an analysis unit configured to derive information on a stool state of the user or information on a state of the large intestine of the user by analyzing the data set, and an output unit configured to output the information on the stool state or the information on the state of the large intestine. The endoscopic activity of ulcerative colitis can be predicted from a camera image of stool even without performing a colonoscopy.

Abstract: The present disclosure is a pharmaceutical composition for the prevention or treatment of sepsis containing a thiamine derivative or a pharmaceutically acceptable salt thereof, wherein the pharmaceutical composition of the present disclosure can be used for the prevention, alleviation, or treatment of sepsis by containing fursultiamine or allithiamine to inhibit the expressions of CD40, CD86, and TNF?.

Abstract: The present invention relates to a ferritin nanocage fused with PD-L1-binding peptide 1 and a use thereof as an anticancer immunotherapy agent. Prepared in the present invention were nanocages that are formed by fusing a human ferritin monomer with a peptide 1 (PD-L1pep1: CLQKTPKQC (SEQ ID NO: 2)) binding to the immune checkpoint receptor PD-L1 overexpressed in many cancers such as breast cancer, colorectal cancer, renal cancer, glioblastoma, etc. and which display 24 Pd-L1prep1.

Abstract: A photosensor includes a vacuum tube having an inner space in which a photoelectron moves, a photocathode unit positioned at an upper portion of the vacuum tube to convert incident light incident from an outside into a photoelectron, a scintillator unit to react with the photoelectron to generate scintillation light, and a photomultiplier to convert the scintillation light into a photoelectron, and multiply the converted photoelectron to generate an electrical signal.

Abstract: The present invention relates to a modified siloxane resin, a crosslinked modified siloxane resin, and a method for preparing the crosslinked resin. More specifically, the present invention relates to a modified siloxane resin, a crosslinked modified siloxane resin with excellent superhydrophobicity obtained by dual curing of the resin, and a method for preparing the crosslinked resin. The use of the modified siloxane resin according to the present invention allows the crosslinked modified siloxane resin to have excellent superhydrophobicity and high hardness. The water repellency of the crosslinked resin can be appropriately controlled by varying the amount of the siloxane resin mixed.

Abstract: Disclosed is a solar energy management method using deep reinforcement learning including receiving, by at least one processor, at least one or more pieces of energy information data for deep reinforcement learning of a deep neural network, calculating, by the at least one processor, a reward value for controlling a solar energy management algorithm constituting the deep neural network using the at least one or more pieces of energy information data and performing the deep reinforcement learning, and determining, by the at least one processor, a schedule for storing, discharging, consuming or selling solar energy by inputting the at least one or more pieces of energy information data as input data of the solar energy management algorithm.

Abstract: The present disclosure relates to magnetic resonance imaging technology for simultaneously measuring a plurality of magnetic resonance imaging parameters.

Abstract: A signal compression method and apparatus and a signal restoration method and apparatus are provided. The signal compression method includes outputting an input signal, obtained by processing an audio signal, which is input, based on a human auditory perception characteristic, using an auditory perception model, extracting a feature vector from the input signal using a feature extraction module, and outputting a code obtained by compressing the feature vector using a trained signal compression model.