Patents Assigned to Lexicon
  • Novel lipoxygenase proteins and polynucleotides encoding the same
    Publication number: 20030172391
    Abstract: The nucleotide and corresponding amino acid sequences are reported for a novel class of mammalian lipoxygenase proteins. The novel lipoxygenase encoding polynucleotides were obtained from human gene trap clones and human cDNA libraries.
    Type: Application
    Filed: April 23, 2003
    Publication date: September 11, 2003
    Applicant: Lexicon Genetics Incorporated
    Inventors: C. Alexander Turner, Brian Zambrowicz, Michael Nehls, Glenn Friedrich, Arthur T. Sands
  • Human kinase proteins and polynucleotides encoding the same
    Patent number: 6617147
    Abstract: Novel human kinase polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: April 24, 2001
    Date of Patent: September 9, 2003
    Assignee: Lexicon Genetics Incorporated
    Inventors: Yi Hu, Boris Nepomnichy, Xiaoming Wang, Gregory Donoho
  • Human kinases and polynucleotides encoding the same
    Patent number: 6610537
    Abstract: Human polynucleotide and polypeptide sequences for novel protein kinases are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: August 9, 2002
    Date of Patent: August 26, 2003
    Assignee: Lexicon Genetics Incorporated
    Inventors: C. Alexander Turner, Jr., Brian Mathur
  • Human adenylsuccinate synthetase and polynucleotides encoding the same
    Patent number: 6607895
    Abstract: Disclosed are a human polynucleotide and the encoded adenylsuccinate synthethase which, can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: April 16, 2002
    Date of Patent: August 19, 2003
    Assignee: Lexicon Genetics Incorporated
    Inventors: Xuanchuan Yu, Maricar Miranda, Emily B. Cullinan
  • Human kinase proteins and polynucleotides encoding the same
    Patent number: 6602698
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: December 7, 2000
    Date of Patent: August 5, 2003
    Assignee: Lexicon Genetics Incorporated
    Inventors: Gregory Donoho, John Scoville, C. Alexander Turner, Jr., Glenn Friedrich, Brian Zambrowicz, Alejandro Abuin, Arthur T. Sands
  • Human kinase and polynucleotides encoding the same
    Patent number: 6593126
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: December 11, 2001
    Date of Patent: July 15, 2003
    Assignee: Lexicon Genetics Incorporated
    Inventors: Yi Hu, James Alvin Kieke, Gregory Donoho
  • Human kinases and polynucleotides encoding the same
    Patent number: 6593125
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: November 19, 2001
    Date of Patent: July 15, 2003
    Assignee: Lexicon Genetics Incorporated
    Inventors: Carl Johan Friddle, Erin Hilbun, Brian Mathur, C. Alexander Turner, Jr.
  • Human kinase and polynucleotides encoding the same
    Patent number: 6586230
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: October 23, 2001
    Date of Patent: July 1, 2003
    Assignee: Lexicon Genetics Incorporated
    Inventors: Yi Hu, Boris Nepomnichy, Brenda Gerhardt, D. Wade Walke, Carl Johan Friddle
  • Human GABA receptor proteins and polynucleotides encoding the same
    Patent number: 6586582
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: January 18, 2001
    Date of Patent: July 1, 2003
    Assignee: Lexicon Genetics Incorporated
    Inventors: C. Alexander Turner, Jr., Brian Mathur, Glenn Friedrich, Brian Zambrowicz, Arthur T. Sands
  • Lipoxygenase proteins and polynucleotides encoding the same
    Patent number: 6582957
    Abstract: The nucleotide and corresponding amino acid sequences are reported for a novel class of mammalian lipoxygenase proteins. The novel lipoxygenase encoding polynucleotides were obtained from human gene trap clones and human cDNA libraries.
    Type: Grant
    Filed: April 12, 2000
    Date of Patent: June 24, 2003
    Assignee: Lexicon Genetics Incorporated
    Inventors: C. Alexander Turner, Jr., Brian Zambrowicz, Michael Nehls, Glenn Friedrich, Arthur T. Sands
  • Human protease inhibitor and polynucleotides encoding the same
    Patent number: 6583269
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: December 18, 2001
    Date of Patent: June 24, 2003
    Assignee: Lexicon Genetics Incorporated
    Inventors: Yi Hu, Boris Nepomnichy, D. Wade Walke
  • Human kinases and polynucleotides encoding the same
    Patent number: 6579710
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: December 12, 2001
    Date of Patent: June 17, 2003
    Assignee: Lexicon Genetics Incorporated
    Inventors: C. Alexander Turner, Jr., Brian Mathur, Carl Johan Friddle
  • Mammalian cortexin-like proteins and polynucleotides encoding the same
    Patent number: 6579715
    Abstract: The human and murine homologues of a novel cortexin-like protein are described.
    Type: Grant
    Filed: January 18, 2000
    Date of Patent: June 17, 2003
    Assignee: Lexicon Genetics Incorporated
    Inventors: Glenn Friedrich, Michael C. Nehls
  • Amide library formation using a “by-product-free” activation/coupling sequence
    Patent number: 6562944
    Abstract: Disclosed is an improved method for preparing an activated carboxylic acid in the form of a pentafluorophenyl ester, an improved method for making a carboxamide from a pentaflourophenyl ester, and a carboxamide and carboxamide library prepared using both of these methods.
    Type: Grant
    Filed: March 22, 2000
    Date of Patent: May 13, 2003
    Assignee: Lexicon Pharmaceuticals
    Inventors: Hartmuth C. Kolb, Qun Sun
  • Human transferase proteins and polynucleotides encoding the same
    Patent number: 6555669
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: February 28, 2001
    Date of Patent: April 29, 2003
    Assignee: Lexicon Genetics Incorporated
    Inventors: Gregory Donoho, Erin Hilbun, C. Alexander Turner, Jr., Glenn Friedrich, Alejandro Abuin, Brian Zambrowicz, Arthur T. Sands, D. Wade Walke, Nathaniel L. Wilganowski, Yi Hu, James Alvin Kieke, David George Potter
  • Novel human LDL receptor family proteins and polynucleotides encoding the same
    Publication number: 20030078383
    Abstract: The present invention relates to LDLPs, nucleotides encoding the same, and methods and compositions for the treatment of biological disorders regulatable by the controlled expression, binding, and/or inhibition of the described LDLPs.
    Type: Application
    Filed: November 12, 2002
    Publication date: April 24, 2003
    Applicant: Lexicon Genetics Incorporated
    Inventors: C. Alexander Turner, Brian Zambrowicz, Glenn Friedrich, Arthur T. Sands
  • Nucleic acids encoding human transporter proteins
    Patent number: 6548271
    Abstract: The present invention provides two novel families of novel human transporter proteins (NTPs). The invention additionally provides for agonists, antagonists, antibodies, antisense molecules that are specific for the NTPs, and further provides genetically engineered expression vectors for the NTPs and host comprising the same. The invention further provides for processes for identifying/producing molecules that effect NTP activity which comprise the use of the disclosed NTPs or genes encoding the same.
    Type: Grant
    Filed: April 21, 2000
    Date of Patent: April 15, 2003
    Assignee: Lexicon Genetics Incorporated
    Inventors: Alex Turner, Brian Zambrowicz, Michael Nehls, Glenn A. Friedrich, Arthur T. Sands
  • Human kinases and polynucleotides encoding the same
    Patent number: 6541252
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: May 14, 2001
    Date of Patent: April 1, 2003
    Assignee: Lexicon Genetics Incorporated
    Inventors: D. Wade Walke, Erin Hilbun, Gregory Donoho, C. Alexander Turner, Jr.
  • Human transporter proteins and polynucleotides encoding the same
    Patent number: 6531309
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: February 28, 2001
    Date of Patent: March 11, 2003
    Assignee: Lexicon Genetics Incorporated
    Inventors: Yi Hu, James Alvin Kieke, Brian Zambrowicz, Jean-Pierre Revelli
  • Human endothelin converting enzyme-like proteins and polynucleotides encoding the same
    Patent number: 6524840
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharamacogenomic applications.
    Type: Grant
    Filed: September 22, 2000
    Date of Patent: February 25, 2003
    Assignee: Lexicon Genetics Incorporated
    Inventors: Gregory Donoho, C. Alexander Turner, Jr., Michael C. Nehls, Glenn Friedrich, Brian Zambrowicz, Arthur T. Sands