Patents Assigned to Lexicon
  • Human thymosin protein and polynucleotides encoding the same
    Patent number: 6887685
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: July 24, 2001
    Date of Patent: May 3, 2005
    Assignee: Lexicon Genetics Incorporated
    Inventors: D. Wade Walke, John Scoville
  • Human proteases and polynucleotides encoding the same
    Patent number: 6881563
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: January 28, 2004
    Date of Patent: April 19, 2005
    Assignee: Lexicon Genetics Incorporated
    Inventors: Gregory Donoho, John Scoville, C. Alexander Turner, Jr., Glenn Friedrich, Alejandro Abuin, Brian Zambrowicz, Arthur T. Sands
  • Human protease inhibitor and polynucleotides encoding the same
    Patent number: 6875587
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications
    Type: Grant
    Filed: April 17, 2003
    Date of Patent: April 5, 2005
    Assignee: Lexicon Genetics Incorporated
    Inventors: Yi Hu, Boris Nepomnichy, D. Wade Walke
  • Human hydroxylases and polynucleotides encoding the same
    Patent number: 6867025
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in industrial, therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: May 23, 2002
    Date of Patent: March 15, 2005
    Assignee: Lexicon Genetics Incorporated
    Inventors: Xuanchuan Yu, Maricar Miranda, Yi Hu
  • Human hemicentin proteins and polynucleotides encoding the same
    Patent number: 6867291
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: September 14, 2001
    Date of Patent: March 15, 2005
    Assignee: Lexicon Genetics Incorporated
    Inventors: C. Alexander Turner, Jr., Brian Mathur, Gregory Donoho
  • Human kinase and polynucleotides encoding the same
    Patent number: 6864079
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: April 4, 2002
    Date of Patent: March 8, 2005
    Assignee: Lexicon Genetics Incorporated
    Inventors: Xuanchuan Yu, Maricar Miranda, Carl Johan Friddle
  • Human kinases and polynucleotides encoding the same
    Patent number: 6861240
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: March 18, 2004
    Date of Patent: March 1, 2005
    Assignee: Lexicon Genetics Incorporated
    Inventors: D. Wade Walke, John Scoville, Carl Johan Friddle
  • Human kinase and polynucleotides encoding the same
    Patent number: 6861241
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: May 11, 2004
    Date of Patent: March 1, 2005
    Assignee: Lexicon Genetics Incorporated
    Inventors: Xuanchuan Yu, Maricar Miranda, Carl Johan Friddle
  • Human kinases and polynucleotides encoding the same, and uses thereof
    Patent number: 6858419
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: November 13, 2001
    Date of Patent: February 22, 2005
    Assignee: Lexicon Genetics Incorporated
    Inventors: D. Wade Walke, Erin Hilbun, Gregory Donoho, C. Alexander Turner, Jr., Gwenn Hansen, Hector BeltrandelRio, Isaac Van Sligtenhorst
  • Indexed library of cells containing genomic modifications and methods of making and utilizing the same
    Patent number: 6855545
    Abstract: Methods and vectors (both DNA and retroviral) are provided for the construction of a Library of mutated cells. The Library will preferably contain mutations in essentially all genes present in the gene of the cells. The nature of the Library and the vectors allow for methods of screening for mutations in specific genes, and for gathering nucleotide sequence data from each mutated gene to provide a database of tagged gene sequences. Such a database provides a means to access the individual mutant cell clones contained in the Library. The invention includes the described Library, methods of making the same, and vectors used to construct the Library. Methods are also provided for accessing individual parts of the Library either by sequence or by pooling and screening. The invention also provides for the generation of non-human transgenic animals which are mutant for specific genes as isolated and generated from the cells of the Library.
    Type: Grant
    Filed: August 15, 2000
    Date of Patent: February 15, 2005
    Assignee: Lexicon Genetics Inc.
    Inventors: Arthur T. Sands, Glenn A. Friedrich, Brian Zambrowicz, Allan Bradley
  • Human protocadherin proteins and polynucleotides encoding the same
    Patent number: 6852844
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: December 19, 2001
    Date of Patent: February 8, 2005
    Assignee: Lexicon Genetics Incorporated
    Inventors: Xuanchuan (Sean) Yu, Maricar Miranda, C. Alexander Turner, Jr.
  • Human proteases and polynucleotides encoding the same
    Patent number: 6852521
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: April 17, 2003
    Date of Patent: February 8, 2005
    Assignee: Lexicon Genetics Incorporated
    Inventors: Gregory Donoho, C. Alexander Turner, Jr., Glenn Friedrich, John Scoville, Brian Zambrowicz, Arthur T. Sands
  • Human kielin-like proteins and polynucleotides encoding the same
    Patent number: 6852840
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: May 11, 2004
    Date of Patent: February 8, 2005
    Assignee: Lexicon Genetics Incorporated
    Inventors: Xuanchuan Yu, John Scoville, Nathaniel L. Wilganowski, Nghi D. Nguyen
  • Human kinases and polynucleotides encoding the same
    Patent number: 6849443
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: January 22, 2002
    Date of Patent: February 1, 2005
    Assignee: Lexicon Genetics Incorporated
    Inventors: C. Alexander Turner, Jr., Brian Mathur
  • Human kinase and polynucleotides encoding the same
    Patent number: 6841377
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenmic applications.
    Type: Grant
    Filed: June 13, 2002
    Date of Patent: January 11, 2005
    Assignee: Lexicon Genetics Incorporated
    Inventors: Yi Hu, Nathaniel L. Wilganowski, Carl Johan Friddle, D. Wade Walke
  • Human G-coupled protein receptor kinases and polynucleotides encoding the same
    Patent number: 6838275
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: August 12, 2002
    Date of Patent: January 4, 2005
    Assignee: Lexicon Genetics Incorporated
    Inventors: D. Wade Walke, Nathaniel L. Wilganowski, C. Alexander Turner, Jr.
  • Human endothelin converting enzyme-like proteins and polynucleotides encoding the same
    Patent number: 6835564
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: November 25, 2002
    Date of Patent: December 28, 2004
    Assignee: Lexicon Genetics Incorporated
    Inventors: Gregory Donoho, C. Alexander Turner, Jr., Michael C. Nehls, Glenn Friedrich, Brian Zambrowicz, Arthur T. Sands
  • Vectors for gene mutagenesis and gene discovery
    Publication number: 20040259253
    Abstract: Novel vectors are described that incorporate, inter alia, a novel 3′ gene trap cassette that does not encode a marker conferring antibiotic resistance and which can be used to efficiently trap, mutagenize, and identify previously unknown cellular genes. Vectors incorporating the presently described 3′ gene trap cassette find particular application in gene discovery, and the production of mutated cells and animals.
    Type: Application
    Filed: March 9, 2004
    Publication date: December 23, 2004
    Applicant: Lexicon Genetics Inc.
    Inventors: Brian Zambrowicz, Glenn A. Friedrich, Stan Lilleberg, Arthur T. Sands
  • Human kinases and polynucleotides encoding the same
    Patent number: 6815188
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: May 8, 2003
    Date of Patent: November 9, 2004
    Assignee: Lexicon Genetics Incorporated
    Inventors: Carl Johan Friddle, Erin Hilbun, Brian Mathur, C. Alexander Turner, Jr.
  • Human secreted proteins and polynucleotides encoding the same
    Patent number: 6815538
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: March 20, 2001
    Date of Patent: November 9, 2004
    Assignee: Lexicon Genetics Incorporated
    Inventors: D. Wade Walke, Nathaniel L. Wilganowski, C. Alexander Turner, Jr., Erin Hilbun, Xiaoming Wang, Gregory Donoho, John Scoville