Abstract: The present disclosure is directed to inhibitors of Formula (0), or a stereoisomer thereof, or pharmaceutically acceptable salt thereof, of the interaction of menin with MLL and MLL fusion proteins, pharmaceutical compositions containing the same, and their use in the treatment of cancer and other diseases mediated by the menin-MLL interaction,

Abstract: A device may obtain a first image depicting contents included in a secure storage container at a first point in time and first user account data associated with the secure storage container. The device may store the first image in a data structure associated with the first user account data. In addition, the device may receive data indicating that an individual associated with a second user account accessed the secure storage container, and receive a second image depicting contents included in the secure storage container at a second point in time. The second image may be stored in the data structure. The device may further receive, from a user device associated with the first user account data, a request to access the data structure, and the device may provide, to the user device, data that causes display of the second image.

Abstract: The invention relates to the soybean variety designated 01083684. Provided by the invention are the seeds, plants and derivatives of the soybean variety 01083684. Also provided by the invention are tissue cultures of the soybean variety 01083684 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety 01083684 with itself or another soybean variety and plants produced by such methods.

Abstract: A method for additively manufacturing a microstructure from a caloric material includes providing a geometry of the microstructure to a processor of an additive manufacturing device, the geometry defining a plurality of microfeatures of the microstructure. The method also includes generating, via the processor, a three-dimensional (3D) model representative of the geometry of the microstructure, wherein one or more of the plurality of microfeatures are represented in the 3D model by a non-arcuate profile. Further, the method includes printing, via the additive manufacturing device, the microstructure from the caloric material according to the 3D model. As such, the non-arcuate profile reduces a file size of the 3D model as compared to an arcuate profile.

Abstract: A test system includes a testing base including a plurality of testing base containers, and a plurality of electrodes integrated into the plurality of testing base containers. The test system further includes a plurality of drive-sense circuits coupled to the plurality of electrodes, where, when enabled, the plurality of drive-sense circuits detect changes in electrical characteristics of the plurality of electrodes. The test system further includes a processing module operably coupled to receive, from the drive-sense circuits, changes in the electrical characteristics of the plurality of electrodes, and interpret the changes in the electrical characteristics of the plurality of electrodes as impedance values representative of electrical characteristics of biological material present in the test container. The test system further includes a communication module operably coupled to communicate the electrical characteristics of the biological material.

Abstract: Implementations are directed to enabling a representative associated with an entity to quickly and efficiently modify a voice bot associated with the entity. The voice bot can be previously trained to communicate with user(s) on behalf of the entity through various communication channels (e.g., a telephone communication channel, a software application communication channel, a messaging communication channel, etc.). Processor(s) of a computing device can receive, from the representative, representative input to modify behavior(s) and/or parameter(s) that the voice bot utilizes in communicating with the plurality of users via the communication channels, determine whether the representative is authorized to cause the behavior(s) and/or parameter(s) to be modified, and cause the behavior(s) and/or parameter(s) to be modified in response to determining that the representative is authorized.

Abstract: The present invention relates to method for producing LED by one step film lamination. The method comprises: laminating two or more LEDs with two or more colored phosphor films by one step film lamination; wherein each of the colored phosphor film comprises each other different colored phosphor composition which has a Maximum tan ?; and the difference of each Maximum tan ? varies within a range of 0-30%. In the present invention, the method for producing a LED may greatly improve production efficiency (i.e., dual and multi-color LEDs in one step) and lower cost of ownership. Further, it may improve uniformity of phosphor dispersion, thereby improve color quality of LEDs.

Abstract: Methods and apparatus to determine engagement levels of audience members are disclosed. An example apparatus includes means for detecting whether an environment associated with a first device includes a second device with a display that is illuminated. The example apparatus also includes means for calculating an engagement of a user with respect to the first device based on a proximity between the user and the illuminated display.

Abstract: Exemplary embodiments are directed to a method and system for transferring a user session between a source device and a target device. The method may include receiving a request to transfer a user session from a source device to the target device, the user session corresponds to a running session between the source device and a session end point device, receiving session data corresponding to the user session transfer request, determining, at the target device, a corresponding launch application for the user session using the session data, launching the corresponding launch application to initiate a transfer of the user session; and replacing the source device in the running session by establishing a communication channel with the session end point device upon the launch of the corresponding launch application using the session data and terminating the user session at the source device.

Abstract: Processes capable of producing bulk materials suitable for use by the horticulture industry, resulting bulk materials produced thereby, and applications for these processes and materials. Preferred bulk materials have physical properties similar to peat moss and comprise individual materials, each at least partially having a twisted, curled, clumped and rolled structure. The individual materials may further comprise small granular particles dispersed throughout the twisted, curled, clumped and rolled structure. The individual materials may be rolled fibers such that the bulk material has physical properties similar to sphagnum peat moss so as to be particularly suitable as, for example, a soil conditioner, an absorbent material, a chemical carrier, or a filtering material. Alternatively, the individual materials may be rolled particles such that the bulk material has physical properties similar to milled peat moss so as to be particularly suitable as propagation media.

Abstract: Some embodiments support embedding of a notebooks software component in a surrounding host application, thereby promoting consistency of notebook user interfaces and user experiences between different kinds of applications. For instance, the notebook access added to an integrated development environment (IDE) may be aesthetically consistent with the notebook access added to a business analytics tool from the same vendor as the IDE. Departures from the aesthetic are still supported, e.g., a notebook access provided in a video gaming environment to teach gamers programming skills may have the same aesthetic as the simulated world of the video game, rather than an IDE aesthetic or an enterprise software aesthetic. Direct integration or proxied integration architectures may be used. Efficiencies may be gained by distinguishing between notebook viewing, editing, and executing operations, and providing more computationally expensive resources only as needed for the notebook access being performed.

Abstract: Systems, methods, and computer-readable media are disclosed for an enhanced valet mode for vehicles. An example method may include receiving a request for a temporary valet passcode. The example method may also include generating a temporary valet passcode. The example method may also include displaying a request for entry of the temporary valet passcode. The example method may also include determining that an input has been received. The example method may also include determining that a mobile device is located within the vehicle or within a threshold distance from the vehicle. The example method may also include preventing the vehicle from starting based on authorization of the mobile device for a period of time subsequent to the input being received.

Abstract: An asset management system is disclosed where a plurality of financial databases may connect with and be in communication with an asset management tool. The asset management tool is able to create an individual spending plan (scheduled distributions) and matching fixed income investment portfolio for a user based on inputted parameters with automatic distributions from the portfolio consistent with the individual spending plan occurring with a high degree of certainty. The asset management tool may communicate with the plurality of financial databases to put the individual spending plan and matching portfolio into action and is able to calculate and communicate an optimized surplus investment as a means of self-insuring so that the predefined schedule of distributions is met with the effective certainty one would expect from an insured/guaranteed income product.

Abstract: Methods and systems for a content server to select sets of video streams having different encoding parameters for transmitting the sets of video streams to a media device are disclosed herein. In some embodiments, a method for transmitting video streams for a media program from a server to a media device includes: selecting, by the server, first encoding parameters including a first bitrate for a first set of video streams for the media program based on a first estimated bandwidth capacity for a network linking the server and the media device, transmitting the first set of video streams from the server to the media device, determining, by the server, second encoding parameters including a second bitrate for a second set of video streams for the media program, and transmitting the second set of video streams from the server to the media device.

Abstract: A surgical tissue connector system for moving a first internal body tissue to a position away from a second internal body tissue and then holding the first internal body tissue in the position. Tissue connectors are secured to cords such that the length of cord between the tissue connectors can be easily adjusted in a laparoscopic work space.

Abstract: Methods, apparatuses, and systems for performing robotic surgery in an extended-reality (XR) surgical simulation environment are disclosed. A patient anatomical model is generated. An XR surgical simulation environment is generated that includes the patient anatomical model. The XR surgical simulation environment is configured to enable the user to virtually perform surgical steps on the patient anatomical model. Anatomical mapping input is received from a user viewing the patient anatomical model. Confidence-score augmented-reality (AR) mapping is performed to meet a confidence threshold for a procedure to be performed on the patient. A portion of the received anatomical mapping data is selected for AR mapping to an anatomy of the patient. The selected anatomical mapping data is mapped to corresponding anatomical features. An AR environment is displayed to the user, wherein the AR environment includes the mapping of the selected anatomical mapping data to the corresponding anatomical features.

Abstract: A firewall intelligence system, includes a data storage storing a set of firewall rules for a network; a recommendation engine that receives, from a log service, traffic logs detailing traffic for the network and firewall logs detailing the usage of firewall rules in response to the traffic for the network, accesses, from the data storage, the set of firewall rules for the network; processes the set of firewall rules to evaluate the firewall rules against a set of quantitative evaluation rules to determine one or more firewall rule recommendations, wherein each firewall rule recommendation is a recommendation to change at least one of the firewall rules in the set of firewall rules; and a front end API that provides data describing the one or more firewall rule recommendations to a user device.