Abstract: The invention relates to a packaging for planiform objects/products such as susceptors, wafers, chewing gum, TTS, TDDS, TDS, stamps, microchips or like. Said packaging consists of a support card (1) with one or more cavities (2) for receiving the object(s). The upper side of said support card is covered by a cover film (3) which occludes the cavities and which is sealed with th support card at sealing lines (4) at least in the marginal area around the cavities in such a manner that sad film can be torn open. Said sealing lines are surrounded by a weakened line (c) the cover film which merges into the contour of a tab (3a) for grasping and manually tearing open the cover film above the respective cavity.
Type:
Grant
Filed:
August 17, 2001
Date of Patent:
February 18, 2003
Assignees:
LTS Lohmann Thapie-Systeme AG, Carl Edelmann GmbH & Co. KG
Inventors:
Michael Fuchs, G{overscore (u)}nter Simon, Notger Weber
Abstract: An adhesive insect trap with a carrier layer, an attractant-containing pressure-sensitive adhesive layer suitable for trapping insects, and a protective layer contains attractant-loaded microparticles in the pressure-sensitive adhesive layer.
Abstract: A transdermal or topical plaster system with a backing layer, with an active ingredient-containing and self-adhesive matrix based on crosslinkable polyacrylate as base polymer and with a removable protecting film is characterized by an at least two-layer matrix with a degree of crosslinking of the layer facing the skin which is appropriate for adequate adhesion to the skin thereof and is lower than the degree of crosslinking of the layer or layers on top thereof.
Abstract: In a process for recovering medicinal substances or active substances from preparations, their initial products or waste, a flat-shaped starting material in the form of a film with adhesive and an active substance-containing material is provided with one edge length of from 0.1 to 5 cm and a second edge length of 50 cm. A starting material having an active substance is placed in an aqueous extraction liquor. The extraction liquor then takes effect until the active substance is dissolved in the aqueous extraction liquor forming an active substance-containing solution. The active substance is isolated from the active substance-containing solution be means of precipitation.
Abstract: The invention relates to a process for cutting laminates intended for application to the skin, including the following steps. (1) a laminate having at least one film and at least one further layer is supplied, (2) the laminate is transported to a cutting area of a laser beam cutting arrangement, whereby it is kept flat in the cutting area under a tension of between 0.1 N/m and 1×104 N/m by tightening the laminate synchronously in all four directions to the tightening plane, and (3) the laminate is cut into or cut through by laser beams.
Abstract: A device and a process for drying thin layers or films which are manufactured by applying a coating mass, which is produced on an aqueous basis, to a support, the said layer or film being transported through a drying device having at least one drying zone, is characterized in that in at least one drying zone, designated as moisture-compensation zone, air is supplied which has a moisture content corresponding to the constant moisture content of the film to be prepared or the layer to be prepared.
Type:
Application
Filed:
September 14, 2001
Publication date:
May 16, 2002
Applicant:
LTS Lohmann Therapie-Systeme AG
Inventors:
Wolfgang Schafer, Peter Schwarz, Rudi Brathuhn, Michael Hoffmann
Abstract: A therapeutic preparation for the transdermal application of active substances through the skin comprising additives causing an increase in the percutaneous absorption rate of active substances which can normally only insufficiently be absorbed transdermally is characterized by the fact that the additives are HMG-CoA-reductase-inhibitors.
Type:
Grant
Filed:
May 5, 1998
Date of Patent:
April 30, 2002
Assignee:
LTS Lohmann Therapie-System Gmbh
Inventors:
Bodo Asmussen, Andreas Koch, Rudolf Matusch
Abstract: A pharmaceutical product for the release of medicinal agents to the skin having absorption-increasing auxiliary agents is characterized in that the auxiliary material forms subcooled melts.
Abstract: The subject matter of the present invention concerns a process for the isolation of the alkaloid galanthamine; the galanthamine itself which has been produced according to this process; the use of the galanthamine thus produced in galenic preparations; and the galanthamine thus produced for treating narrow-angle glaucoma, Alzheimer's disease, as well as alcohol and nicotine dependence.
Type:
Grant
Filed:
December 21, 2000
Date of Patent:
January 1, 2002
Assignee:
LTS Lohmann Therapie-Systeme GmbH
Inventors:
Thomas Hille, Hans-Rainer Hoffmann, Mirko Kreh, Rudolf Matusch
Abstract: Pharmaceutical composition comprising (S)-N-ethyl-3-[1-dimethylamino)ethyl]-N-methyl-phenyl-carbamate in free base or acid addition salt form and an anti-oxidant. Said pharmaceutical compositions may be delivered to a patient using a transdermal delivery device.
Type:
Grant
Filed:
April 14, 1999
Date of Patent:
January 1, 2002
Assignees:
Novartis AG, LTS Lohmann Therapie-Systeme GmbH Co. KG
Inventors:
Bodo Asmussen, Michael Horstmann, Kai Köpke, Henricus L. G. M. Tiemessen, Steven Minh Dinh, Paul M. Gargiulo
Abstract: In a solid medicament form for the peroral application of active agents containing a uniform distribution of active agent in a polymer material, the polymer material is in the form of flat fragments.
Type:
Grant
Filed:
July 10, 1997
Date of Patent:
December 25, 2001
Assignee:
LTS Lohmann Therapie-Systeme GmbH
Inventors:
Bodo Asmussen, Walter Müller, Karsten Cremer
Abstract: Pharmaceutical composition comprising (S)-N-ethyl-3-[1-dimethylamino)ethyl]-N-methyl-phenyl-carbamate in free base or acid addition salt form and an antioxidant. Said pharmaceutical compositions may be delivered to a patient using a transdermal delivery device.
Abstract: A process for continuously manufacturing transdermal therapeutic patches having a backing layer, a pressure-sensitive adhesive drug reservoir layer, and a removable protective layer, whereby loss of active substances during fabrication of the patches is minimized, said process being characterized in that, in a tape-like laminate having a pressure-sensitive adhesive backing layer (1) and a removable protective layer (3), single quadrangular pressure-sensitive adhesive drug reservoir sections (2) are inserted one after the other in the longitudinal direction between the layers (2,3); the clearance between said drug reservoir sections remains constant in the longitudinal direction; their width is calculated such that the backing layer (1) and the removable protective layer (3) project beyond both sides of said sections; the pressure-sensitive adhesive backing layer (1) is first cut by punching in such a way that the punching line (1a) surrounds the individual drug reservoir sections (2) at an evident distance fr
Type:
Grant
Filed:
September 22, 1995
Date of Patent:
November 13, 2001
Assignee:
LTS Lohmann Therapie-Systeme GmbH & Co. KG
Inventors:
Dieter Anhauser, Lothar Deurer, Thomas Hille, Peter Steinborn
Abstract: A process for the production of an extremely flexible patch having a dermal or transdermal action and having an adhesive matrix layer which comprises the active compound and is provided with a detachable protective layer on a side facing the skin is characterized in that the matrix layer is not covered on the side facing away from the skin but is given a non-adhesive treatment on its open surface.
Abstract: The present invention describes a device for the controlled release of active compounds in the gastrointestinal tract with delayed pyloric passage, having a component expandable on contact with gastric juice, which is surrounded by a polymer covering which is permeable to gastric juice and active compounds. The device contains at least one active compound which is present in a multiparticulate preparation which releases the active compound into the gastric juice with a delay. Compared with conventional pharmaceutical forms with delayed pyloric passage, the release of active compound from a device according to the invention can be better controlled; likewise the device can be easily rolled or folded and can be introduced into capsules without problems.
Type:
Grant
Filed:
August 31, 1999
Date of Patent:
September 18, 2001
Assignee:
LTS Lohmann Therapie-Systeme AG
Inventors:
Bodo Asmussen, Karsten Cremer, Hans-Rainer Hoffmann, Karin Ludwig, Michael Roreger
Abstract: A composition containing therapeutic agents and/or breath freshening agents for use in the oral cavity is disclosed. The carrier comprises water-soluble polymers in combination with certain ingredients and provides a therapeutic and/or cosmetic effect. The film is coated and dried utilizing existing coating technology and exhibits instant wettability followed by rapid dissolution/disintegration upon administration in the oral cavity.
Type:
Grant
Filed:
August 2, 2000
Date of Patent:
September 4, 2001
Assignee:
LTS Lohmann Therapie-Systeme GmbH
Inventors:
Horst Georg Zerbe, Jian-Hwa Guo, Anthony Serino
Abstract: An active ingredient-containing transdermal therapeutic system with a nonadhesive backing layer, with an active ingredient-containing reservoir layer and with a self-adhesive surface facing the skin, where appropriate with redetachable protecting layer, is characterized by an elastic or plastically extensible diffusible backing layer with a metal layer which acts as permeability barrier for auxiliaries and active ingredients in the reservoir layer and is formed by film growth, in particular a metallization layer.
Type:
Grant
Filed:
October 1, 1999
Date of Patent:
August 21, 2001
Assignee:
LTS Lohmann Therapie-Systeme AG
Inventors:
Michael Horstmann, Walter Müller, Wolfgang Laux
Abstract: An active compound-containing patch for the controlled delivery of oestradiol or its pharmaceutically acceptable derivatives, alone or in combination with gestagens, to human or animal skin, having an active compound-containing reservoir based on ethylcellulose and contact adhesives comprising adhesive resins is characterized by a contact adhesive having a high plasticizer content.
Abstract: A pharmaceutical lozenge for the modified release of active compounds in the gastrointestinal tract is described, with active-compound-containing particles which have a first coating controlling the release and a further, outer coating with saliva-resistant properties. The first coating, which controls the release of active compound, can have release-delaying or enteric properties.
Abstract: A therapeutic system for supplying active substances to the skin consists of a backing layer remote from the skin, with at least one active substance depot. The depot may consist of a fluid active substance or a fluid composition comprising an active substance delivery control matrix. There is also included an adhesive fixing device for fixing the therapeutic system on the skin. The therapeutic system is characterized in that the active substance depots (14) consist of at least one adjuvant having a supporting and distributing function by being provided with a planar textile material completely surrounded by matrix (12).