Abstract: Esophageal intubation assemblies, esophageal cardiac stimulation and gastric decompression assemblies, and methods for using and making the same are provided.

Abstract: In an embodiment, an electronic device includes a display screen, a memory circuit, and computing circuitry, which is coupled to the display screen and to the memory circuit, and which is configured to cause the display screen to display icons that are each related to respective data regarding a patient at a medical facility, to retrieve, from the memory, the respective data in response to a user of the electronic device selecting, via the display screen, a corresponding one of the displayed icons, and to cause the display screen to display the retrieved respective data.

Abstract: An implantable medical product and method of use for substantially reducing or eliminating harsh biological responses associated with conventionally implanted medical devices, including inflammation, infection and thrombogenesis, when implanted in in a body of a warm blooded mammal. The bioremodelable pouch structure is configured and sized to receive, encase and retain an electrical medical device therein and to allow such device to be inserted into the internal region or cavity of the pouch structure; with the pouch structure formed from either: (a) first and second sheets, or (b) a single sheet having first and second sheet portions. After receiving the electrical device, the edges around the opening are closed by suturing or stapling. The medical device encased by the bioremodelable pouch structure effectively improves biological functions by promoting tissue regeneration, modulated healing of adjacent tissue or growth of new tissue when implanted in the body of the mammal.

Abstract: This invention describes a wound dressing product for active continuous debridement of devitalized tissues in non-healing wounds including diabetic ulcers, pressure ulcers, burn injuries and other etiologies. The present invention pertains to the principle of continuous wound debridement which makes necrotic tissue more susceptible for removal and hence enhances progressive wound healing. The dressing contains an active ingredient, such as collagenase which serves to debride wounds in-situ. In the present invention purified Collagenase (90% pure) was deposited onto several wound dressing materials. A key feature of this invention is that the activity level of the Collagenase used was substantially preserved.

Abstract: This invention describes a wound dressing product for active continuous debridement of devitalized tissues in non-healing wounds including diabetic ulcers, pressure ulcers, burn injuries and other etiologies. The present invention pertains to the principle of continuous wound debridement which makes necrotic tissue more susceptible for removal and hence enhances progressive wound healing. The dressing contains an active ingredient, such as collagenase which serves to debride wounds in-situ. In the present invention purified Collagenase (90% pure) was deposited onto several wound dressing materials. A key feature of this invention is that the activity level of the Collagenase used was substantially preserved.

Abstract: A medical ablation catheter, an ablation system, and an ablation method. The medical ablation catheter comprises a first catheter (1); a second catheter (2), comprising an inner catheter (21) and an outer catheter (22); a conductive part (3), connected to the first catheter (1) and the inner catheter (21), the distal end of the conductive part (3) being fixed within the first catheter (1), the proximal end of the conductive part (3) being fixed on the inner catheter (21); an adjustment part (4), the distal end thereof being fixed within the first catheter (1), the proximal end thereof being movably arranged within the inner catheter (21) in a penetrating manner. The conductive part (3) can be switched between a linear state and an expanded state, and ablation is performed when the conductive part (3) is in the expanded state.

Abstract: A head stabilization device useable for stabilizing a head of a patient during a medical procedure includes a modular design where stabilization assemblies of various configurations are interchangeable at receiving portions along a frame. The device includes a tensioning feature positioned away from the stabilization assembly but still operable to increase or decrease an amount of force the stabilization assembly applies to the patient's head. The device includes a locking feature for a stabilization assembly having a rotatable member having one or more stabilization features connected thereto. The device includes an adjustment feature to adjust a spacing between frame members with the adjustment feature providing a continuous range of adjustment rather than finite adjustment increments.

Abstract: A binocular device for visualizing optical radiation including a support structure, a left and right camera coupled to the support structure. The left camera comprising left optics and a left image sensor, the right camera comprising right input optics and a right image sensor, the left image sensor and the right image sensor being configured to create left and right video signals from detected optical radiation received from the corresponding left and right input optics about a same field of view along respective left and right input optical axes. A light source coupled to the structure, for generating radiation in the invisible wavelength band and visible light, wherein the light is configured to intermittently emit the invisible light while keeping the visible light intensity constant, wherein the left or right camera captures an image with the emitted invisible light and an image without the emitted invisible light.

Abstract: The present invention relates to a drug aerosol supply apparatus for a respirator, and the objective of the present invention is to prevent secondary respiratory infection due to condensation water. The drug aerosol supply apparatus according to the present invention comprises a T tube, a drug particulate generation unit and a heater. The T tube includes a straight tube having a first end portion to which air provided from a respirator is provided and having a second end portion connected to a mask or a mouthpiece, and a branch tube attached to the straight tube so as to allow communication with the straight tube. The drug particulate generation unit is installed at the branch tube and sprays a drug in a particulate state. The heater for heats the T tube.

Abstract: The invention relates to the compound urolithin A and its compositions for topical use in inflammatory skin conditions of various etiologies. Anti-inflammatory activity has been demonstrated in vivo in a model of inflammation of the ear caused by infiltration with dinitrochlorobenzene in rats. Topical application of an ointment containing 0.2 and 1.0% urolithin A resulted in a decrease in ear edema and scratching frequency, which was associated with a decrease in the number of immune cells responsible for the progression of inflammation. The results obtained indicate the possibility of using a composition containing urolithin A in local therapy of skin inflammations, in treatment of which hydrocortisone or other steroids are currently used.

Abstract: It is provided a method for manufacturing viruses in an in vitro cell culture. The method comprising the following steps: providing a cell culture of avian epithelial cells chosen from at least one of the cell cultures deposited under deposition numbers DSM ACC3345, DSM ACC3346, DSM ACC3347, DSM ACC3348, DSM ACC3349 at Leibniz-Institut DSMZ-Deutsche Sammlung von Mikroorganismen and Zellkulturen GmbH on Dec. 12, 2018; infecting at least some of the cells in the cell culture with virus particles; incubating the cells for a first period of time; and recovering viruses produced by the cell culture from a supernatant of the cell culture.

Abstract: A lead assembly for insertion into a body passage such as the lumen of a vein is particularly applicable for assembly of a cardiac pacemaker. In one version the lead has a distal end with an end portion of a flexible sheath attached with the sheath initially extending outwardly from the distal end and subsequently folded in an annular U-fold over the lead to provide a sheath along the length. By applying tensile force to the proximal end of the lead, the annular fold causes the material of the sheath to peel away from any surrounding scar tissue as the lead is pulled out towards the proximal end and provides for easy nondestructive extraction of the lead. In another version, a single layer flexible sheath is attached at the distal end of a lead, and, upon application of a tensile force to the stretchable sheath, the lead can be extracted.

Abstract: A system and method for sealing openings in a body of a patient made by a medical procedure or non-medical event. The opening may be formed in soft tissue, internal organs, or hard tissue. A coaxial needle is inserted into a patient and a coagulating agent is inserted into the patient via the coaxial needle. The coagulating agent is discharged adjacent to the opening and the coaxial needle is inserted to a surgical depth. Following the procedure, the coaxial needle is retracted to a plug discharging depth. A bioabsorbable plug in at least a partially dehydrated state is then discharged from the coaxial needle and the coaxial needle is removed. The plug resides at least partially within the opening in the organ or tissue created by the coaxial needle. The combination of the coagulating agent and the expandable plug seals the opening created by the coaxial needle.

Abstract: A sublingual phentermine spray composition for daytime use comprises phentermine in a pharmaceutically-acceptable carrier and a sublingual phentermine spray composition for nighttime use comprises phentermine and a sleep aid in a pharmaceutically-acceptable carrier. Sublingual administration of sublingual phentermine spray compositions in accordance with the present disclosure provides an alternative to oral administration, avoiding such side effects as daytime drowsiness and intestinal disturbances. Nighttime use compositions comprising a sleep aid such as melatonin help manage the usual insomnia experienced when using phentermine. These compositions find use in suppressing appetite, for losing weight, and for maintaining a desired personal appearance.

Abstract: A sublingual phentermine spray composition for daytime use comprises phentermine in a pharmaceutically-acceptable carrier and a sublingual phentermine spray composition for nighttime use comprises phentermine and a sleep aid in a pharmaceutically-acceptable carrier. Sublingual administration of sublingual phentermine spray compositions in accordance with the present disclosure provides an alternative to oral administration, avoiding such side effects as daytime drowsiness and intestinal disturbances. Nighttime use compositions comprising a sleep aid such as melatonin help manage the usual insomnia experienced when using phentermine. These compositions find use in suppressing appetite, for losing weight, and for maintaining a desired personal appearance.

Abstract: Provided is a composition for promoting hair growth, which comprises a mixture comprising an extract of Polygonum multiflorum Thunb and silver nanoparticles; and Copper Tripeptide-1, wherein the weight/volume ratio of the Copper Tripeptide-1 to the composition for promoting hair growth is from 0.1 mg/mL to 0.2 mg/mL; wherein the mixture comprising the extract of Polygonum multiflorum Thunb and silver nanoparticles comprises the silver nanoparticles, extract of Polygonum multiflorum Thunb, a stabilizer, and a diluent. The present invention further provides a pharmaceutical composition for promoting hair growth comprising the composition and a pharmaceutically acceptable excipient, and a method for promoting hair growth by administering the pharmaceutical composition to a subject. The composition for promoting hair growth of the present invention can increase hair growth and stimulate the growth of new hair follicles.

Abstract: An autoloading screwdriver apparatus is provided which includes a base; a screw cartridge received by the base; a driver supported within the base that is selectively engageable with a screw of the screw cartridge by manually displacing the driver toward a working end of the autoloading screwdriver apparatus; and a handle grip movably coupled to the base and configured to be manually displaced in a longitudinal direction toward the working end of the autoloading screwdriver apparatus to move the driver into engagement with the screw and to displace the screw to the working end of the autoloading screwdriver apparatus for presenting the screw to be screwed into a target substrate. The autoloading screwdriver apparatus may further include a control element manipulable by a user to activate rotational movement of the driver to drive the screw into the target substrate.

Abstract: A fabric or mesh construct, and process for making same, which allows for early wound stability and then transitions to a more compliant state exhibiting a substantially constant macro-porous pore structure through the life of the implant to promote good tissue incorporation without bridging.

Abstract: The present disclosure discloses compositions comprising a hyper-concentrated hyaluronidase, devices comprising such compositions, as well as methods and uses employing such compositions and devices to reduce or eliminate a hyaluronic acid-induced blockage of one or more blood vessels supplying blood to an area of tissue of an individual; methods and uses for employing such compositions and devices to reduce or inhibit a vascular occlusion in an area of tissue of an individual; and methods and uses for employing such compositions and devices to reduce or inhibit a hyaluronic acid-induced loss of tissue of an individual.

Abstract: Provided is a glycated hemoglobin measuring apparatus. The apparatus for measuring glycated hemoglobin includes a cartridge for receiving blood and a plurality of chemicals, a rotating tray for rotating the cartridge, wherein the cartridge is disposed inside the rotating tray, a driver having a nozzle disposed above the cartridge and movable in a vertical direction, and a measurement unit located above the cartridge and measuring glycated hemoglobin of the blood, wherein the driver sucks at least one of the blood, the plurality of chemicals, and mixed solution of the blood and the plurality of chemicals into the nozzle or discharges the sucked at least one into the cartridge such that the blood is chemically treated through the plurality of chemicals.