Patents Assigned to Med
  • Polymers for additive manufacturing
    Patent number: 11578204
    Abstract: Porous and microporous parts prepared by additive manufacturing as disclosed herein are useful in medical and non-medical applications. The parts are prepared from a composition containing both a solvent soluble component and a solvent insoluble component. After a part is printed by an additive manufacturing process it is exposed to solvent to extract solvent soluble component away from the printed part, resulting in a part having surface cavities.
    Type: Grant
    Filed: August 31, 2018
    Date of Patent: February 14, 2023
    Assignee: POLY-MED, INC.
    Inventors: Michael Scott Taylor, James Hyde, Brian Gaerke, Brad Johns, Michael Aaron Vaughn, Seth Dylan McCullen, David Gravett
  • METHOD FOR TREATING DIABETES AND NONALCOHOLIC FATTY LIVER DISEASE, ASSOCIATED CONDITION OR DISORDER THEREOF, OR SYMPTOMS THEREOF
    Publication number: 20230037676
    Abstract: The present invention provides a method for treating diabetes and nonalcoholic fatty liver disease (NAFLD), associated condition or disorder thereof, or symptoms thereof suffered by a subject such as a mammal (e.g. a human patient or a pet), comprising (1) placing one or more electrodes within a target blood vessel of the subject and against the target blood vessel wall, wherein the target blood vessel includes the celiac artery and/or a segment of the abdominal aorta terminated at its junction with the celiac artery; (2) adhering a surface electrode on an external surface such as skin of the subject; and (3) releasing a therapeutically effective amount of radiofrequency energy through the one or more electrodes to nearby tissues, so as to increase the temperature of the nearby tissues and induce a thermal alteration of the nearby tissues.
    Type: Application
    Filed: October 2, 2022
    Publication date: February 9, 2023
    Applicant: SHANGHAI GOLDEN LEAF MED TEC CO., LTD.
    Inventors: Hongguang CAO, Haidong CHEN, Jiulin GUO, Meijun SHEN
  • EXTRACELLULAR MATRIX STRUCTURES
    Publication number: 20230026971
    Abstract: A sheet structure comprising two joined extracellular matrix (ECM) tissue or sheet layers and a physiological sensor disposed therebetween; the ECM tissue being derived from a mammalian tissue source that includes small intestine submucosa (SIS), urinary bladder submucosa (UBS), stomach submucosa (SS), urinary basement membrane (UBM), liver basement membrane (LBM), amniotic membrane, mesothelial tissue, placental tissue and cardiac tissue.
    Type: Application
    Filed: March 31, 2022
    Publication date: January 26, 2023
    Applicant: Aziyo Med, LLC
    Inventor: Robert G. Matheny
  • Warming device and infusion system
    Patent number: 11559636
    Abstract: Provided is a warming device which can efficiently warm a blood product and inhibit a liquid in a warming flow path from exceeding an upper limit temperature thereof when liquid delivery of the blood product is stopped. The warming device includes the warming flow path in which the blood product flows and a heat plate which is in contact with the warming flow path to supply heat to the warming flow path. On the heat plate, a heater in a predetermined pattern corresponding to the warming flow path is disposed. The heater is disposed such that an amount of heat generation toward the warming flow path decreases in stages from an upstream side toward a downstream side in the warming flow path and that a decrease rate of the amount of heat generation at each of the stages decreases from the upstream side toward the downstream side.
    Type: Grant
    Filed: September 27, 2017
    Date of Patent: January 24, 2023
    Assignee: MED-TECH INC.
    Inventors: Noriaki Yoshioka, Taisuke Funamoto
  • Synthetic implant device replicating natural tissue structure and methods of making same
    Patent number: 11549197
    Abstract: A composite implant device for use in a medical application, comprising a synthetically-derived mesh that mimics particular critical aspects of a biologically-derived mesh. The composite implant device can be used for the reinforcement and reconstruction of tissues within the body and can be comprised of a majority of synthetic components and minority of naturally-derived components which mimic the structure and function of a naturally-derived mesh.
    Type: Grant
    Filed: November 12, 2020
    Date of Patent: January 10, 2023
    Assignee: Poly-Med, Inc.
    Inventors: Seth Dylan McCullen, Clayton Joseph Culbreath, Michael Aaron Vaughn, Michael Scott Taylor
  • METHOD OF CORRECTING AMPLIFICATION BIAS IN AMPLICON SEQUENCING
    Publication number: 20230005568
    Abstract: A method to correct amplification bias in amplicon sequencing is disclosed. Amplification efficiency is not constant among different loci in a sample, nor for the same locus in different samples. Differences in 3?-end stability, primer Tm, amplicon length, amplicon GC content, and GC content of amplicon flanking regions all may contribute to amplification bias. Such bias interferes with accurate calculation of copy number for a genomic region of interest and hinders the application of amplicon sequencing for detection of minor copy number variation. The methods of the invention allow correction of amplification bias and enable detection of minor copy number variation using amplicon sequence data.
    Type: Application
    Filed: September 12, 2022
    Publication date: January 5, 2023
    Applicant: CELULA CHINA MED-TECHNOLOGY CO., LTD.
    Inventors: Di Wu, Haichuan Zhang
  • Treatment of cancer cells overexpressing somatostatin receptors using ocreotide derivatives chelated to radioisotopes
    Patent number: 11541133
    Abstract: A cancer targeting composition, kit, and method for treatment of cancer cells overexpressing somatostatin receptors is disclosed. The composition includes a radioisotope, a chelator, and a targeting moiety. The chelator includes a nitrogen ring structure including a tetraazacyclododecane, a triazacyclononane, and/or a tetraazabicyclo [6.6.2] hexadecane derivative. The targeting moiety includes a somatostatin receptor targeting peptide. The somatostatin receptor targeting peptide includes an octreotide derivative. The targeting moiety is chelated to the radioisotope by the chelator whereby the cancer cells are targeted for elimination.
    Type: Grant
    Filed: January 12, 2018
    Date of Patent: January 3, 2023
    Assignees: RADIOMEDIXINC., ORANO MED
    Inventors: Izabela Tworowska, Nilesh Wagh, Ebrahim S. Delpassand, Federico Rojas-Quijano, Paul Jurek, Garry E. Kiefer, Tania A. Stallons, Amal Saidi, Julien Torgue
  • Internal pedicle insulator
    Patent number: 11540920
    Abstract: A pedicle insulator implant is designed to protect the nerves and surrounding tissue from injury by pedicle screws or other surgical devices and instruments. The implant is configured to shield a fixture, reduce nerve root irritation, and diminish loosening of the fixture, when the fixture is implanted into the void of a target site. The implant includes features for stabilizing and securing the implant within the void at the target site. For example, in one embodiment, the implant includes one or more ridges and one or more teeth sections that stabilize the implant against rotational and extractive forces that could disturb the implant.
    Type: Grant
    Filed: October 17, 2019
    Date of Patent: January 3, 2023
    Assignee: CHAP-MED, INC.
    Inventor: James L. Chappuis
  • INSTALLATION FOR THE THREE-DIMENSIONAL PRINTING OF A MEDICAL DEVICE
    Publication number: 20220413463
    Abstract: The invention relates to an installation (1) for the three-dimensional printing of a medical device directly at a location where the medical device is to be used. According to the invention, the installation comprises a container (2) comprising inside it: a production module (3) comprising a 3D printer (6); a clean room (4) comprising means (12) for washing and disinfection of the printed medical device, and a machine (13) for packaging the washed and disinfected medical device.
    Type: Application
    Filed: May 21, 2020
    Publication date: December 29, 2022
    Applicant: MED IN TOWN
    Inventor: Jérôme PRECHEUR
  • Navigatable implantable electrode and collapsing lubricant reservoir
    Patent number: 11524154
    Abstract: An implantable electrode arrangement for a cochlear implant system includes an elongated electrode array for insertion into a patient cochlea. A fluid delivery channel is located within the electrode array parallel to a central longitudinal axis with at least one fluid delivery port for delivering lubricant fluid from the fluid delivery channel to the outer surface of the electrode array. The fluid delivery port and the lubricant fluid are configured to produce a lubrication region close to the outer surface of the electrode array proximal to the fluid delivery port during insertion of the electrode array into the patient cochlea so as to reduce insertion resistance at an adjacent section of lateral wall of the patient cochlea.
    Type: Grant
    Filed: November 9, 2018
    Date of Patent: December 13, 2022
    Assignee: MED-EL Elektromedizinische Geraete GmbH
    Inventor: Anandhan Dhanasingh
  • PYRIDOPYRIMIDINONE COMPOUNDS AND APPLICATIONS THEREOF
    Publication number: 20220389013
    Abstract: The present disclosure provides the Pyridopyrimidinone compounds having the structure represented by the general Formula (II) and applications thereof. Studies have shown that the compounds provided by the present disclosure can effectively inhibit the KRAS G12C mutation. KRAS mutation accounts for a large proportion of tumors, and currently there is no approved drug for its treatment. The compounds provided by the present disclosure have the potential to become a therapeutic medicine for malignant tumors (especially non-small cell lung cancer (NSCLC) and colorectal cancer) haboring KRAS G12C mutation, and have great application value.
    Type: Application
    Filed: July 20, 2022
    Publication date: December 8, 2022
    Applicant: BeBetter Med Inc.
    Inventors: Xiong CAI, Yunwo WENG, Yuanhui QING, Mingsheng LIN, Bin LIU, Qijie HE, Yiting LIU, Qiao FENG, Fushun FAN, Changgeng QIAN
  • Atrial appendage clip
    Patent number: 11504133
    Abstract: Disclosed is an atrial appendage clip, including a first clip arm and a second clip arm that are symmetrically arranged; a first cavity and a second cavity are correspondingly provided in the first clip arm and the second clip arm along an axial direction thereof; a first spring and a second spring are correspondingly provided in the first cavity and the second cavity; the first spring is connected with the second clip arm via a first pull wire, and the second spring is connected with the first clip arm via a second pull wire, so as to form a closed loop structure; and as the first spring and the second spring are stretched or compressed, the first clip arm and the second clip arm are opened or closed therebetween.
    Type: Grant
    Filed: December 29, 2016
    Date of Patent: November 22, 2022
    Assignee: BEIJING MED ZENITH MEDICAL SCIENTIFIC CO., LTD.
    Inventors: Qingliang Zhou, Danian Ke, Jian Meng, Xiaofang Liu
  • Non-pneumatic surgical tourniquet
    Patent number: 11504134
    Abstract: A non-pneumatic tourniquet including a tourniquet ring configured to resiliently constrict around a body part of a subject. The tourniquet ring defines a plurality of openings. A handle moves the tourniquet ring onto the body part and includes a first strap having a first end secured to the tourniquet ring at one of the openings and a second end secured to the tourniquet ring at one of the openings. A second strap has a first end secured to the tourniquet ring at one of the openings and a second end secured to the tourniquet ring at one of the openings.
    Type: Grant
    Filed: September 28, 2017
    Date of Patent: November 22, 2022
    Assignee: MAR-MED INC.
    Inventor: Jerry Paul Marogil
  • SUCTION VALVE OF ENDOSCOPE
    Publication number: 20220361734
    Abstract: Disclosed is a suction valve for an endoscope, the endoscope including a first conduit and a second conduit, the suction valve including a shaft, a pressing unit, and a holding seat; wherein a first opening and a second opening are provided at a bottom and a sidewall of the shaft, respectively; the holding seat is sleeved in the shaft, and a middle portion of the shaft projects outward to form a ridge, the pressing unit including a bump, a first slot being provided at a sidewall of the holding seat, the bump being snap-fitted with the first slot.
    Type: Application
    Filed: April 21, 2022
    Publication date: November 17, 2022
    Applicant: SML Med-Tech Solutions Limited
    Inventor: Tsz Hang Ko
  • Systems and methods for treating a vessel using focused force
    Patent number: 11497901
    Abstract: A device for introduction into a body vessel includes a main elongated element, a balloon positioned at the main elongated element distal end, a distal connecting element positioned at the distal end of the balloon to receive a guidewire during use, and a longitudinally movable sheath positioned external to the main elongated element, a position of the sheath distal end with respect to the balloon defining an exposed portion of the balloon that expands when fluid is delivered to the balloon through the inflation lumen.
    Type: Grant
    Filed: July 22, 2019
    Date of Patent: November 15, 2022
    Assignee: Y-MED, INC.
    Inventors: Ronald J. Solar, Yoav Shaked
  • RADIO FREQUENCY ABLATION CATHETER HAVING FUNCTION OF MOVING GUIDE WIRE
    Publication number: 20220346868
    Abstract: A radio frequency ablation catheter having the function of a movable guide wire, comparing an electric support, a catheter body and a control handle which are sequentially provided. The catheter body is provided there with a cavity for the sliding of the movable guide wire. The distal end of the movable guide wire passes through the catheter body and protects from the distal end of the electric support, a soft guide wire provided at the distal end of the movable guide wire is always kept outside the electric support. The proximal end of the movable guide wire protects from the proximal end of the catheter body and enters the control handle, then, the proximal end of the movable guide wire is fixed to a controlling member provided on the control handle or is fixed to a controlling member provided outside the control handle.
    Type: Application
    Filed: July 18, 2022
    Publication date: November 3, 2022
    Applicant: SHANGHAI GOLDEN LEAF MED TEC CO., LTD.
    Inventors: Hongguang CAO, Meijun SHEN
  • Thermally and dimensionally stabilized compositions and methods of making same
    Patent number: 11486058
    Abstract: Thermally stable absorbable fiber populations, i.e. fiber populations that do not undergo thermally induced crystallization, can be intermixed with thermally unstable fibers to yield a stabilizing effect without altering morphological properties of a fiber system. Via this, one may minimize thermally induced shrinkage and maintain physical properties of electrospun materials in the as-formed state.
    Type: Grant
    Filed: March 19, 2020
    Date of Patent: November 1, 2022
    Assignee: Poly-Med, Inc.
    Inventors: Michael Scott Taylor, Seth Dylan McCullen
  • Medical implants having managed biodegradation
    Patent number: 11478348
    Abstract: Medical implants that include a containment layer surrounding, or surrounded by, a biodegradable medical device provide the benefit that pieces formed during degradation of the medical device are held within a constrained place and thus do not causes injury to a hosts.
    Type: Grant
    Filed: June 23, 2017
    Date of Patent: October 25, 2022
    Assignee: POLY-MED, INC.
    Inventors: Michael Scott Taylor, Jennifer Cartledge, Kenneth David Gray, Jr.
  • CONTAINER DEVICE FOR BREAST PROSTHESIS FOR RECONSTRUCTIVE BREAST SURGERY
    Publication number: 20220331091
    Abstract: Medical device for breast reconstruction for containing or integrating a breast implant, the device being designed for placement between the skin and the pectoralis major muscle and is configured to be sutured to the pectoralis major muscle. The device includes a container body having a half shell and a flat appendage joined continuously to a portion of the base of the half shell.
    Type: Application
    Filed: July 28, 2020
    Publication date: October 20, 2022
    Applicant: DECO MED SRL
    Inventor: Giovanni BERTOLI
  • Digital tourniquet
    Patent number: D973874
    Type: Grant
    Filed: July 29, 2021
    Date of Patent: December 27, 2022
    Assignee: MAR-MED INC.
    Inventor: Jerry Paul Marogil