Abstract: A wearable medical device, system and method are disclosed herein. The wearable medical device is placeable on a target site of a subject's body and includes a rotary coupling component and an electrode patch. When the electrode patch is attached to the rotary coupling component, electrodes of the patch's electrode array are electrically coupled to corresponding tracks of the conductive tracks. The wearable medical device also includes an ultrasound scanning and biomarker monitoring module having a set of conductive contacts. When the ultrasound scanning and biomarker monitoring module is attached to the rotary coupling component opposite the electrode patch, the set of conductive contacts are engaged with corresponding tracks of the conductive tracks. The ultrasound scanning and biomarker monitoring module is further configured to rotate about the rotary coupling component with the conductive contacts remaining engaged with the corresponding tracks during rotation.

Abstract: The present invention provides an anchor delivery device for repairing a heart valve, and relates to the technical field of medical instruments. The system comprises a bend adjustable tube assembly, an anchor delivery assembly, a suture locking mechanism, and a puncture assembly. The anchor delivery assembly is mounted in the bend adjustable tube assembly; the suture locking mechanism is connected to an anchor, and is provided with a guide portion located in the anchor; and the puncture assembly is mounted in an anchor delivery tube, and a puncture needle body of the puncture assembly penetrates the guide portion and is radially limited by the guide portion. According to the present invention, the puncture accuracy of the puncture needle body and the stability thereof after puncture can be ensured, and the accuracy and stability of the subsequent implantation of the anchor are improved.

Abstract: The present invention provides an implant delivery handle, an implant system, a delivery system and a method of operation thereof. The implant delivery handle includes two conveyance sub-systems both oriented along an axial direction of a catheter assembly, in which a distal one is coupled to a proximal portion of an outer tube in the catheter assembly, and a proximal one is coupled to a proximal portion of an inner tube in the catheter assembly. Each of the conveyance sub-systems comprises a synchronous conveying device and a ratchet device fixed to the synchronous conveying device. The ratchet device is configured to enable safe self-locking, transmission and guidance of the outer or inner tube through the synchronous conveying device. In this way, both the inner and outer tubes can be locked in one direction, avoiding opposite movement of the inner or outer tube caused by incorrect operation of an operator.

Abstract: An apparatus and a method are disclosed for implementing axial focal region temperature measurement distribution detection through a lateral probe. The apparatus includes a temperature measurement module, an imaging ultrasound module, a lateral imaging probe, a ranging module, and a position control module. The imaging ultrasound module sends an electrical pulse signal to the lateral imaging probe, and obtains an ultrasound image and ultrasound radio frequency data through the lateral imaging probe; an axial of the lateral imaging probe always intersects with an axis of a focused ultrasound transducer; the temperature measurement module controls the lateral imaging probe to perform cyclic scanning on a temperature measurement ROI region through the position control module; and the ranging module is configured to obtain a mapping depth of focus D of the temperature measurement ROI region within a field of view of the lateral imaging probe.

Abstract: A method for depositing a coating comprising a polymer and pharmaceutical agent on a substrate, comprising the following steps: discharging at least one pharmaceutical agent in a therapeutically desirable morphology in dry powder form through a first orifice; discharging at least one polymer in dry powder form through a second orifice; depositing the polymer and/or pharmaceutical particles onto said substrate, wherein an electrical potential is maintained between the substrate and the pharmaceutical and/or polymer particles, thereby forming said coating; and sintering said coating under conditions that do not substantially modify the morphology of said pharmaceutical agent.

Abstract: The present invention provides a method of treating or alleviating erectile dysfunction in a patient. Multiple electrodes are placed within a segment of the internal iliac artery of the patient and against blood vessel wall of the internal iliac artery. Radiofrequency energy is released through at least one of the multiple electrodes to nearby tissues, so as to increase the temperature of the nearby tissues and induce a thermal alteration of the nearby tissues.

Abstract: Degradable bioprostheses made of collagen-based material having amine-based and ester-based crosslinks are provided, as are methods for their formation and use. Some embodiments of the present invention are directed towards a method of controlling the ratio of amine-based crosslinks to ester-based crosslinks within a collagen-based material to provide a tailorably crosslinked collagen-based material. Some embodiments provide a method of making a degradable bioprosthesis involving controlling crosslinking to afford a degradable bioprosthesis that is partially crosslinked. By controlling the ratio of amine-based to ester-based crosslinks, by controlling the level of crosslinking, or by controlling both of these features, degradable bioprostheses with tailored degradation rates can be synthesized. Some embodiments of degradable bioprostheses have degradation rates that are tailored to allow their use in particular medical applications.

Abstract: A pre-loadable dried biological heart valve and a preparation method thereof. The preparation method includes: Step A: soaking a fresh animal pericardium in an aqueous solution of soluble elastin or glycosaminoglycan, and then subjecting the pericardium to a first cross-linking reaction in a mixed solution of carbodiimide or N-hydroxysuccinimide to allow the soluble elastin or glycosaminoglycan to bind to the pericardium via a chemical bond; and Step B: subjecting the pericardium after the first cross-linking to a second cross-linking reaction in an aqueous glutaraldehyde solution, and then drying the pericardium after the second cross-linking, to obtain the pre-loadable dried biological heart valve. The dried biological heart valve obtained by the above preparation method has good toughness, and is rapidly flattened out in a simulated folding and pressing test.

Abstract: A therapeutic method for myocardial repair, includes providing a therapeutic needle, introducing the treatment needle to pierce from an epicardium into the myocardium without passing through an endocardium, and injecting therapeutant for myocardial repair through the treatment needle.

Abstract: The present disclosure provides a system for ablation of uterine fibroid(s), said system comprising: an ultrasound scanner configured to perform a volume scan of a uterus of a patient; a display coupled with the ultrasound scanner, configured for displaying image and alphanumeric characters; a device comprising an electrode for ablating the uterine fibroid; a controllable energy source coupled with the electrode and configured to supply energy to the electrode.

Abstract: The present invention discloses a medical suture and a medical suture device, and belongs to the field of medical instruments. The medical suture comprises: a suture body, the suture body defining a longitudinal center line; and a plurality of pairs of barbs arranged at intervals along a direction of the longitudinal center line, each pair of barbs being symmetrically arranged on opposite sides of the suture body, the barb being provided with a first end connected with the suture body and a second end far away from the suture body, and a ratio of a transverse distance L1 of second ends of each pair of the barbs along a direction perpendicular to the longitudinal center line to a transverse dimension L0 of the suture body perpendicular to the direction of the longitudinal center line ranging from 1.5 to 2.5.

Abstract: Systems and methods may be used for registering a force input on a portion of a surgical robot, for example using a force sensor of the surgical robot. The force input may correspond to a control command. The control command may generate a change in a control mode of the surgical robot, validate a step of a workflow in planning or navigation software, or the like. A visual indication may be provided, for example using a light of the surgical robot. The visual indication may indicate that the control command has been identified or executed.

Abstract: A prosthetic heart valve for deployment between the right atrium (1) and the right ventricle (2) includes an outer stent layer (100), a skirt (200) and prosthetic leaflets (300). The outer stent layer (100) includes a flange section (110), a main section (120) and an attachment section (130), which are sequentially joined along an axial direction. The flange section (110) has a diameter gradually increasing in the axial direction away from the main section (120) and is configured to be pressed on the tricuspid valve annulus (3). The main section (120) is configured to be seated inside of the tricuspid valve leaflet (4). The attachment section (130) includes a septal leaflet attachment tine (131) and an anterior and posterior leaflet attachment tine (132).

Abstract: A repair device for treatment of tricuspid regurgitation includes a support frame, an occlusive membrane, and a suture line. The support frame includes a central shaft and anchoring members that are disposed around the central shaft and radially unfolded for anchoring leaflets of a tricuspid valve. The occlusive membrane surrounds connections between the anchoring members and the central shaft, and the occlusive membrane is connected to the support frame through the suture line. A semi-closed space surrounding the central shaft is formed by an outer side wall of the central shaft, the anchoring members and the occlusive membrane, and has a closed end in proximity to a ventricle and an open end in proximity to an atrium. The central shaft has a closed end in proximity to the ventricle. The repair device for treatment of tricuspid regurgitation reduces the number of implants, thereby reducing the side effects caused by implantation.

Abstract: Embodiments of the present disclosure provide a clip instrument. The clip instrument may include a clip arm and a locking part. The clip arm may include at least two clips for clamping at least one tissue and at least two extending parts releasably connected to the at least two clips, respectively. The clip arm has an open state and a closed state, wherein the at least two clips are spaced apart from each other when the clip arm is in the open state to form a space for clamping the at least one tissue, and the at least two clips are close to each other when the clip arm is in the closed state. The locking part may be configured to lock two clips of the at least two clips when a distance between the two clips is less than a preset distance.

Abstract: A strain gauge includes: a substrate; a transverse sensitive grid arranged on the substrate; and at least two non-transverse sensitive grids arranged on the substrate so as to be located on opposite sides of the transverse sensitive grid both electrically connected to the transverse sensitive grid. The two non-transverse sensitive grids are connected to each other by a connection and share a common ground lead and a common ground interface. One end of the ground lead is connected to the connection at the middle thereof. The other end of the ground lead is connected to the ground interface. The two non-transverse sensitive grids have equal resistances and are connected to ends of two respective non-ground leads having equal resistances. The other ends of the two non-ground leads are connected to two respective non-ground interfaces.

Abstract: A valve prosthesis includes a stent (10) and a skirt assembly. The stent (10) has an inflow end (11) and an outflow end (12) opposite to the inflow end along an axial direction of the stent. The skirt assembly includes at least two skirts (20) surrounding the stent (20) in the shape of rings and each having an inner edge (21) and an outer edge (22). The inner edge (21) is an edge of the skirt (20) closer to an axis of the stent (10), and the outer edge (22) is an edge of the skirt (20) farther away from the axis of the stent (10). The inner edge (21) is attached to the stent (10), and the outer edge (22) forms a free end. The at least two skirts (20) are arranged with a spacing along the axial direction of the stent (10) and have different radial outer dimensions, and at least one of the skirts (20) is configured to be brought into contact at its outer edge (22) with native tissue (50).

Abstract: The invention provides a stent loading system and a method using the same for loading a stent into a sheath. The stent includes a stent body, and an outer periphery of one end of the stent body is provided with a hook. The stent loading system includes a hook straightener for straightening the hook on the stent and a compressor, wherein the stent in which the hook is straightened is reduced in diameter and crimped through the compressor, and the stent crimped is delivered into a preloaded tube; the stent is connected with a delivery system penetrating in the sheath, and the stent in the preloaded tube is delivered into the sheath under the traction of the delivery system.