Patents Assigned to Menicon Co., Ltd.
  • Publication number: 20210163650
    Abstract: A silicone-containing polymer material containing an internal wetting agent and being excellent in transparency, the silicone-containing polymer material being improved in antifouling property against lipids. The polymer material of the present invention is a polymer material, which is obtained by polymerizing a polymerizable mixture containing monomer components (a) and a hydrophilic polymer component (b), wherein the monomer components (a) include a silicone-containing monomer (a-1) having a siloxane bond and being free of any hydroxyl group, and a compatibilizing monomer (a-2) having a hydrogen bonding proton-containing group and being free of any silicon atom, and wherein the compatibilizing monomer has four or more carbon atoms, excluding carbon atoms contained in a polymerizable functional group, and has a solubility of less than 0.03 g/mL in water at 25° C.
    Type: Application
    Filed: February 21, 2020
    Publication date: June 3, 2021
    Applicant: MENICON CO., LTD.
    Inventors: Kohsuke SATAKE, Kengo ASAI, Kazuhiro SUNAHARA, Yurika SATAKE
  • Patent number: 11009723
    Abstract: Provided is an ophthalmic diffractive multi-focal lens with a diffractive structure including a phase profile in which a plurality of blaze shaped zones are set in a concentric circle form, wherein: at least one of the zones serves as an adjustment zone wherein an inclination direction in the phase profile is reversed with respect to that of other zones; and a light intensity level giving a peak or focal point at a position away from three focal points in a light intensity distribution of transmitted light in an optical axis direction is kept low in comparison with a phase profile without the adjustment zone.
    Type: Grant
    Filed: February 9, 2016
    Date of Patent: May 18, 2021
    Assignee: MENICON CO., LTD.
    Inventor: Ichiro Ando
  • Publication number: 20210061858
    Abstract: Provided is an immunogenic composition which contains a self-assembling peptide as an adjuvant and can increase the immunogenicity of various antigens. The present invention provides an immunogenic composition including: a peptide hydrogel containing a positively or negatively charged self-assembling peptide and an aqueous medium; and an antigen, in which the self-assembling peptide is not covalently bonded to the antigen.
    Type: Application
    Filed: January 18, 2019
    Publication date: March 4, 2021
    Applicant: MENICON CO., LTD.
    Inventor: Miya FUJIMOTO
  • Publication number: 20210061933
    Abstract: The present invention provides a material for intraocular lens which has improved hydrolysis resistance. The material for intraocular lens according to the present invention is obtained by polymerizing a monomer composition comprising: a base monomer, a hydrophilic monomer, and a cross-likable monomer, wherein the base monomer comprises an aromatic ring-containing acrylate monomer and an alkoxyalkyl methacrylate monomer having an alkoxyalkyl group having four or less carbon atoms. A blending ratio on a molar basis of the methacrylate monomer with respect to the acrylate monomer in all the monomer components contained in the monomer composition is 0.25 to 1.00.
    Type: Application
    Filed: January 31, 2018
    Publication date: March 4, 2021
    Applicant: MENICON CO., LTD.
    Inventors: Yuya SUGANUMA, Hiroko NOMURA, Tatsuya OJIO, Keishi TSUKAMOTO
  • Patent number: 10821136
    Abstract: The present invention provides a bone formation promoter having high biological safety and capable of promoting bone formation. The bone formation promoter of the present invention includes a self-assembling peptide capable of forming a ?-sheet structure in an aqueous solution having a neutral pH; and a bone chip. A sum of charges of amino acid residues constituting the self-assembling peptide at pH 7.0 is unequal to 0.
    Type: Grant
    Filed: June 29, 2015
    Date of Patent: November 3, 2020
    Assignees: NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM, MENICON CO., LTD.
    Inventors: Kei Ando, Naoki Ishiguro, Shiro Imagama, Zenya Ito, Yasuhiro Yokoyama, Hidenori Yokoi, Yusuke Nagai
  • Publication number: 20200268928
    Abstract: A disinfection system of a contact lens comprising immersing the contact lens in a disinfecting solution containing hydrogen peroxide in a concentration of 1 to 10% and neutralizing the hydrogen peroxide in the disinfecting solution through contact with a metal catalyst, where the disinfecting solution contains an organic carboxylic acid or a salt of the organic carboxylic acid, the organic carboxylic acid having a structure in which a hydroxyl group and a carboxyl group are bonded to one carbon atom; the disinfecting solution is adjusted to have a pH of 6 to 8; and the disinfecting solution after the neutralization is adjusted to have an osmotic pressure of 250 to 350 mOsm.
    Type: Application
    Filed: May 13, 2020
    Publication date: August 27, 2020
    Applicant: MENICON CO., LTD.
    Inventors: Osamu MORI, Yukihiro KOJIMA
  • Patent number: 10747022
    Abstract: A diffractive multi-focal lens having a diffractive structure comprising a plurality of concentric circular zones, wherein: at least a portion of the diffractive structure is provided with an overlapping region in which at least two zone profiles overlap in the same region; in the overlapping region, at least a portion of a first zone profile has a zone pitch represented by a prescribed equation, and at least a portion of a second zone profile has a zone pitch represented by another prescribed equation; and an addition power P1 given by the first zone profile and an addition power P2 given by the second zone profile are determined by a prescribed relational expression, in which a and b are mutually different real numbers, and a value of a/b cannot be expressed by a natural number X or by 1/X.
    Type: Grant
    Filed: August 8, 2014
    Date of Patent: August 18, 2020
    Assignee: MENICON CO., LTD.
    Inventors: Ichiro Ando, Atsushi Kobayashi
  • Patent number: 10716875
    Abstract: An intraocular lens includes a polymeric lens material formed from a polymerizable composition. The polymerizable composition includes: (a) a single aromatic acrylate monomer which is an aromatic-ring containing acrylate; (b) an alkoxyalkyl methacrylate monomer having an alkoxyalkyl group with 4 or less carbon atoms; (c) an alkyl acrylate monomer having an alkyl group with 1 to 20 carbon atoms; (d) a hydrophilic monomer; and (e) a crosslinkable monomer.
    Type: Grant
    Filed: January 31, 2018
    Date of Patent: July 21, 2020
    Assignee: MENICON CO., LTD
    Inventors: Yuya Suganuma, Hiroko Nomura, Tatsuya Ojio, Keishi Tsukamoto
  • Patent number: 10702606
    Abstract: The present invention provides a peptide composition that can achieve both excellent storage stability and transparency. The peptide composition of the present invention includes: a self-assembling peptide; a buffering agent having a pKa of 3.5 or more and less than 7.5 and containing one or more nitrogen atoms; and water, and has a pH of from 4.5 to 6.6.
    Type: Grant
    Filed: December 10, 2015
    Date of Patent: July 7, 2020
    Assignee: MENICON CO., LTD.
    Inventors: Yuya Suganuma, Tatsuya Ojio, Hidenori Yokoi
  • Patent number: 10632204
    Abstract: The present invention provides a peptide composition that can achieve both excellent storage stability and transparency. The peptide composition of the present invention includes: a self-assembling peptide; a buffering agent having a pKa of 3.5 or more and less than 7.5 and containing one or more nitrogen atoms; and water, and has a pH of from 4.5 to 6.6.
    Type: Grant
    Filed: December 10, 2015
    Date of Patent: April 28, 2020
    Assignee: MENICON CO., LTD.
    Inventors: Yuya Suganuma, Tatsuya Ojio, Hidenori Yokoi
  • Patent number: 10564448
    Abstract: The present invention pertains to a diffractive multi-focal ophthalmic lens, and the purpose is to provide a novel structure and manufacturing method in which improvement in optical characteristics such as halo reduction is obtained. A diffractive multi-focal ophthalmic lens in which a plurality of focal points are set by a diffraction grating comprising a blaze shaped phase function in which a plurality of zone sequences are overlapped, wherein adopted is a structure expressed by a phase function in which an inclination of a blaze of a specific adjustment zone in a standard profile is reversed.
    Type: Grant
    Filed: October 1, 2015
    Date of Patent: February 18, 2020
    Assignee: MENICON CO., LTD.
    Inventor: Ichiro Ando
  • Publication number: 20200038548
    Abstract: An intraocular lens includes a polymeric lens material formed from a polymerizable composition. The polymerizable composition includes: (a) a single aromatic acrylate monomer which is an aromatic-ring containing acrylate; (b) an alkoxyalkyl methacrylate monomer having an alkoxyalkyl group with 4 or less carbon atoms; (c) an alkyl acrylate monomer having an alkyl group with 1 to 20 carbon atoms; (d) a hydrophilic monomer; and (e) a crosslinkable monomer.
    Type: Application
    Filed: January 31, 2018
    Publication date: February 6, 2020
    Applicant: MENICON CO., LTD.
    Inventors: Yuya SUGANUMA, Hiroko NOMURA, Tatsuya OJIO, Keishi TSUKAMOTO
  • Patent number: 10478104
    Abstract: A contact lens includes a glucose sensor which can determine when a detectable concentration of glucose is present in the optical fluids of the user. The glucose sensor can transition between a first state and a second state relative to the concentration of glucose within the optical fluid of the user. The glucose sensor can be bonded or otherwise attached or incorporated into the contact lens. While the contact lens is worn in the user's eye, either the user or another person can view the contact lens to quickly determine if an excessive amount of glucose is present in the user's system.
    Type: Grant
    Filed: March 12, 2019
    Date of Patent: November 19, 2019
    Assignee: MENICON CO., LTD.
    Inventor: Mouad Lamrani
  • Patent number: 10444542
    Abstract: A decentered type contact lens including: an optical zone provided in a center part of the contact lens; a peripheral zone provided on an outer circumference of the optical zone; an optical center of the optical zone being set to deviate from a lens geometric center; and a circumferential direction alignment mechanism for setting a lens circumferential direction position in a worn state, the contact lens being characterized in that: a center-of-gravity deviation in relation to the lens geometric center is set for the peripheral zone, and a center-of-gravity position shift accompanying deviation of the optical center of the optical zone in relation to the lens geometric center is corrected by offset using the center-of-gravity deviation of the peripheral zone.
    Type: Grant
    Filed: March 4, 2014
    Date of Patent: October 15, 2019
    Assignee: MENICON CO., LTD.
    Inventors: Yuji Goto, Mitsuhiko Nakada
  • Patent number: 10444540
    Abstract: The purpose of the present invention is to provide novel contact lens manufacturing method and contact lens capable of giving a lens inner surface shape reflecting a cornea shape of a contact lens wearer more easily than before with sufficient accuracy to reflect the cornea shape, thereby improving comfort during use. By using statistical information on a corneal surface shape obtained from a population of target eyes having a feature to be treated, a fitting for a rotationally-symmetric shape is performed based on a definitional equation using a radius of curvature (R) and a conic constant (C.C.) while a fitting for a rotationally-asymmetric shape is performed based on a definitional equation using a Zernike function. A shape of a lens rear surface (20) corresponding to the corneal surface shape specified by these definitional equations is adopted for a rear surface of a peripheral area of a contact lens (10).
    Type: Grant
    Filed: July 13, 2018
    Date of Patent: October 15, 2019
    Assignee: MENICON CO., LTD.
    Inventors: Atsushi Kobayashi, Hiroaki Suzuki
  • Publication number: 20190151493
    Abstract: A disinfection system of a contact lens comprising immersing the contact lens in a disinfecting solution containing hydrogen peroxide in a concentration of 1 to 10% and neutralizing the hydrogen peroxide in the disinfecting solution through contact with a metal catalyst, where the disinfecting solution contains an organic carboxylic acid or a salt of the organic carboxylic acid, the organic carboxylic acid having a structure in which a hydroxyl group and a carboxyl group are bonded to one carbon atom; the disinfecting solution is adjusted to have a pH of 6 to 8; and the disinfecting solution after the neutralization is adjusted to have an osmotic pressure of 250 to 350 mOsm.
    Type: Application
    Filed: October 18, 2018
    Publication date: May 23, 2019
    Applicant: MENICON CO., LTD.
    Inventors: Osamu MORI, Yukihiro KOJIMA
  • Patent number: 10295841
    Abstract: A method for manufacturing a diffractive multi-focal ophthalmic lens capable of generating at least three focal points in an optical axis direction using a diffractive structure comprising a plurality of zones in a concentric circle form. A composite profile is generated by overlapping at least two starting profiles comprising a plurality of zones in a concentric circle form, and an adjusted profile is generated in which at least one of phase and amplitude is adjusted by employing a zone of the composite profile as a subject in order to set an intensity distribution in the optical axis direction and determine optical characteristics, to manufacture the diffractive multi-focal ophthalmic lens for which the adjusted profile is provided in at least a portion of the diffractive structure.
    Type: Grant
    Filed: August 5, 2015
    Date of Patent: May 21, 2019
    Assignee: MENICON CO., LTD.
    Inventor: Ichiro Ando
  • Patent number: 10281740
    Abstract: The purpose of the present invention is to provide novel contact lens manufacturing method and contact lens capable of giving a lens inner surface shape reflecting a cornea shape of a contact lens wearer more easily than before with sufficient accuracy to reflect the cornea shape, thereby improving comfort during use. By using statistical information on a corneal surface shape obtained from a population of target eyes having a feature to be treated, a fitting for a rotationally-symmetric shape is performed based on a definitional equation using a radius of curvature (R) and a conic constant (C.C.) while a fitting for a rotationally-asymmetric shape is performed based on a definitional equation using a Zernike function. A shape of a lens rear surface (20) corresponding to the corneal surface shape specified by these definitional equations is adopted for a rear surface of a peripheral area of a contact lens (10).
    Type: Grant
    Filed: July 15, 2014
    Date of Patent: May 7, 2019
    Assignee: MENICON CO., LTD.
    Inventors: Atsushi Kobayashi, Hiroaki Suzuki
  • Patent number: D899080
    Type: Grant
    Filed: October 30, 2018
    Date of Patent: October 20, 2020
    Assignee: MENICON CO., LTD.
    Inventors: Akihiro Yasuda, Keisuke Yamamoto, Keiko Yamamoto
  • Patent number: D899081
    Type: Grant
    Filed: December 7, 2018
    Date of Patent: October 20, 2020
    Assignee: MENICON CO., LTD.
    Inventors: Keisuke Yamamoto, Katsuhiro Iwai, Akihiro Yasuda, Keiko Yamamoto, Takashi Goto