Abstract: A system for collecting and utilizing health data can include collecting data relative to a patient's health and aggregating the data with other sources of data to define a database. The patient data can be collected using an electronic device, such as a smart contact lens or smart contact lens container. The data within the database can be manipulated, organized, or otherwise processed to determine trends, relationships, and other characteristics of the database. The characteristics of the database can be correlated to predict a health condition of the patient, generate a healthcare recommendation, or a combination thereof.

Abstract: The additive polymer is an additive polymer capable of increasing a tensile fracture strength and a toughness of a silicone hydrogel to add to the silicone hydrogel. The additive polymer includes a benzotriazole skeleton and does not have a polymerizable group.

Abstract: A novel method for producing a contact lens whereby it is possible to solve at least one problem that becomes an obstacle when equipping a contact lens with a separate component such as an electronic element. When matching a component-supporting mold supporting a component to be embedded with a first mold, performing curing treatment of a first molding material, and thereby obtaining a primary molded article in which the component is inserted, the component-supporting mold is removed while curing of the first molding material is incomplete on the component-supporting mold side. A second mold is subsequently matched with the first mold in which the primary molded article is left, filled with a second molding material, and curing treatment is performed, thereby producing a contact lens as an integrally molded product in which the component is embedded.

Abstract: A silicone-containing polymer material containing an internal wetting agent and being excellent in transparency, the silicone-containing polymer material being improved in antifouling property against lipids. The polymer material of the present invention is a polymer material, which is obtained by polymerizing a polymerizable mixture containing monomer components (a) and a hydrophilic polymer component (b), wherein the monomer components (a) include a silicone-containing monomer (a-1) having a siloxane bond and being free of any hydroxyl group, and a compatibilizing monomer (a-2) having a hydrogen bonding proton-containing group and being free of any silicon atom, and wherein the compatibilizing monomer has four or more carbon atoms, excluding carbon atoms contained in a polymerizable functional group, and has a solubility of less than 0.03 g/mL in water at 25° C.

Abstract: A silicone-containing polymer material containing an internal wetting agent and being excellent in transparency, the silicone-containing polymer material being improved in antifouling property against lipids. The polymer material of the present invention is a polymer material, which is obtained by polymerizing a polymerizable mixture containing monomer components (a) and a hydrophilic polymer component (b), wherein the monomer components (a) include a silicone-containing monomer (a-1) having a siloxane bond and being free of any hydroxyl group, and a compatibilizing monomer (a-2) having a hydrogen bonding proton-containing group and being free of any silicon atom, and wherein the compatibilizing monomer has four or more carbon atoms, excluding carbon atoms contained in a polymerizable functional group, and has a solubility of less than 0.03 g/mL in water at 25° C.

Abstract: A contact lens includes a body, having the plurality of monomers including at least some silicone monomer units including at least one zwitterionic distributed throughout the body. The contact lens includes a front surface and a back surface, where the silicone monomer including at least one zwitterionic group can be present in a greater concentration nearest the front surface than the back surface or a point therebetween. The contact lens can be formed by casting a polymer mixture containing the silicone monomer including at least one zwitterionic group.

Abstract: A disinfection system of a contact lens comprising immersing the contact lens in a disinfecting solution containing hydrogen peroxide in a concentration of 1 to 10% and neutralizing the hydrogen peroxide in the disinfecting solution through contact with a metal catalyst, where the disinfecting solution contains an organic carboxylic acid or a salt of the organic carboxylic acid, the organic carboxylic acid having a structure in which a hydroxyl group and a carboxyl group are bonded to one carbon atom; the disinfecting solution is adjusted to have a pH of 6 to 8; and the disinfecting solution after the neutralization is adjusted to have an osmotic pressure of 250 to 350 mOsm.

Abstract: Provided is an ocular device case with a new structure that can solve unexpected problems in the related art, for example, adverse effects on user's eyes by splashes of treatment liquid upon pouring the treatment liquid into the device case from a separate refill container. In a device case 10 including: a case body 18 accommodating treatment liquid 12 with ocular devices such as a contact lens 16; and a lid 20, a container receiving portion 48 is provided such that a spout 106 of a refill container 100 is brought into contact with the refill receiving portion 48 so as to allow the treatment liquid 12 to flow into the device case 10.

Abstract: Determination system including: a computing device (i) obtaining information related to an eye of a target person from a plurality of data sources and (ii) making a determination of a predetermined matter related to the target person based on at least part of the information. The plurality of data sources include two or more of a sensor included in a contact lens of the target person, a sensor included in a storage container of the contact lens, a measurement device which carries out measurement related to the eye of the target person, tear fluid of the target person, a storage solution of the contact lens and, a diagnostic process of the target person.

Abstract: A disinfection system of a contact lens comprising immersing the contact lens in a disinfecting solution containing hydrogen peroxide in a concentration of 1 to 10% and neutralizing the hydrogen peroxide in the disinfecting solution through contact with a metal catalyst, where the disinfecting solution contains an organic carboxylic acid or a salt of the organic carboxylic acid, the organic carboxylic acid having a structure in which a hydroxyl group and a carboxyl group are bonded to one carbon atom; the disinfecting solution is adjusted to have a pH of 6 to 8; and the disinfecting solution after the neutralization is adjusted to have an osmotic pressure of 250 to 350 mOsm.

Abstract: An ocular device case with a new structure that can solve unexpected problems in the related art, for example, adverse effects on user's eyes by splashes of treatment liquid upon pouring the treatment liquid into the device case from a separate refill container. In a device case including: a case body accommodating treatment liquid with ocular devices such as a contact lens; and a lid, a container receiving portion is provided such that a spout of a refill container is brought into contact with the refill receiving portion so as to allow the treatment liquid to flow into the device case.

Abstract: The present invention provides an ocular lens which achieves both of oxygen permeability and surface hydrophilicity, and on which the deposition of lipids is suppressed. The ocular lens of the present invention includes a polymer material obtained by polymerizing a polymerizable composition containing, as monomer components, a siloxane monomer having a siloxane bond, and a siloxane-free crosslinkable monomer free of any siloxane bond, wherein the siloxane-free crosslinkable monomer includes an alkylene glycol chain-containing crosslinkable monomer having: a chain moiety containing 6 or more alkylene glycol repeating units; and polymerizable groups arranged at both terminals of the chain moiety.

Abstract: A material or method that can serve as an alternative to a related-art digestive fluid leak preventative material and method of preventing a leak of a digestive fluid, the digestive fluid leak preventative material includes a self-assembling peptide gel, has an adhesion persistence ratio with respect to a collagen sheet of at least 40%, and has a decomposition ratio of 35% or less in pancreatic juice treatment at 37° C. for 7 days.

Abstract: The present invention provides a material for intraocular lens which has improved hydrolysis resistance. The material for intraocular lens according to the present invention is obtained by polymerizing a monomer composition comprising: a base monomer, a hydrophilic monomer, and a cross-likable monomer, wherein the base monomer comprises an aromatic ring-containing acrylate monomer and an alkoxyalkyl methacrylate monomer having an alkoxyalkyl group having four or less carbon atoms. A blending ratio on a molar basis of the methacrylate monomer with respect to the acrylate monomer in all the monomer components contained in the monomer composition is 0.25 to 1.00.

Abstract: Provided is an immunogenic composition which contains a self-assembling peptide as an adjuvant and can increase the immunogenicity of various antigens. The present invention provides an immunogenic composition including: a peptide hydrogel containing a positively or negatively charged self-assembling peptide and an aqueous medium; and an antigen, in which the self-assembling peptide is not covalently bonded to the antigen.

Abstract: An ocular device case with a new structure that can solve unexpected problems in the related art, for example, adverse effects on user's eyes by splashes of treatment liquid upon pouring the treatment liquid into the device case from a separate refill container. In a device case including: a case body accommodating treatment liquid with ocular devices such as a contact lens; and a lid, a container receiving portion is provided such that a spout of a refill container is brought into contact with the refill receiving portion so as to allow the treatment liquid to flow into the device case.

Abstract: An ophthalmic medical device including a photochromic polymer having higher transparency under an inactive state through use of a photochromic monomer. An ophthalmic medical device according to one embodiment that includes a photochromic polymer obtained by polymerizing monomer components including a photochromic monomer and a lactam ring-containing monomer, wherein a content ratio of the lactam ring-containing monomer in the monomer components is from 10 wt % to 50 wt %. The ophthalmic medical device is typically a contact lens or an intraocular lens.

Abstract: A disinfection system of a contact lens comprising immersing the contact lens in a disinfecting solution containing hydrogen peroxide in a concentration of 1 to 10% and neutralizing the hydrogen peroxide in the disinfecting solution through contact with a metal catalyst, where the disinfecting solution contains an organic carboxylic acid or a salt of the organic carboxylic acid, the organic carboxylic acid having a structure in which a hydroxyl group and a carboxyl group are bonded to one carbon atom; the disinfecting solution is adjusted to have a pH of 6 to 8; and the disinfecting solution after the neutralization is adjusted to have an osmotic pressure of 250 to 350 mOsm.

Abstract: A disinfection system of a contact lens comprising immersing the contact lens in a disinfecting solution containing hydrogen peroxide in a concentration of 1 to 10% and neutralizing the hydrogen peroxide in the disinfecting solution through contact with a metal catalyst, where the disinfecting solution contains an organic carboxylic acid or a salt of the organic carboxylic acid, the organic carboxylic acid having a structure in which a hydroxyl group and a carboxyl group are bonded to one carbon atom; the disinfecting solution is adjusted to have a pH of 6 to 8; and the disinfecting solution after the neutralization is adjusted to have an osmotic pressure of 250 to 350 mOsm.

Abstract: A nail cosmetic composition contains a silicone macromonomer as a base material having at least two polymerizable functional groups and a polymerization initiator with respect to the silicone macromonomer. A method of using a nail cosmetic composition includes a painting step of painting a nail cosmetic composition described above on a nail and a curing step of exposing the nail cosmetic composition to light with an illuminance of 80 mW/cm2 or less at dominant wavelength at an exposure time within three minutes per one layer to cure the nail cosmetic composition. The nail cosmetic resin contains a silicone unit in which a silicone macromonomer has been polymerized as the base material having at least two polymerizable functional groups.