Abstract: The present invention provides an ocular lens which achieves both of oxygen permeability and surface hydrophilicity, and on which the deposition of lipids is suppressed. The ocular lens of the present invention includes a polymer material obtained by polymerizing a polymerizable composition containing, as monomer components, a siloxane monomer having a siloxane bond, and a siloxane-free crosslinkable monomer free of any siloxane bond, wherein the siloxane-free crosslinkable monomer includes an alkylene glycol chain-containing crosslinkable monomer having: a chain moiety containing 6 or more alkylene glycol repeating units; and polymerizable groups arranged at both terminals of the chain moiety.

Abstract: A plant stress tolerance-inducing agent is provided that contains, as an active ingredient, a compound having a specific quinone skeleton. Alternatively, a plant stress tolerance-inducing agent is provided that contains, as an active ingredient, at least one compound selected from the group consisting of 1,4-naphthoquinone, 5-hydroxy-1,4-naphthoquinone, 5,8-dihydroxy-1,4-naphthoquinone, 2-hydroxy-1,4-naphthoquinone, 5-hydroxy-2-methyl-1,4-naphthoquinone, 2,3-dichloro-1,4-naphthoquinone, 2,3-dichloro-5,8-dihydroxy-1,4-naphthoquinone, 2,3-dichloro-5-nitro-1,4-naphthoquinone, 2,3-dichloro-6-nitro-1,4-naphthoquinone, 2-methoxy-1,4-naphthoquinone, 2-amino-3-chloro-1,4-naphthoquinone, a shikonin compound, and an alkannin compound.

Abstract: A material or method that can serve as an alternative to a related-art digestive fluid leak preventative material and method of preventing a leak of a digestive fluid, the digestive fluid leak preventative material includes a self-assembling peptide gel, has an adhesion persistence ratio with respect to a collagen sheet of at least 40%, and has a decomposition ratio of 35% or less in pancreatic juice treatment at 37° C. for 7 days.

Abstract: The present invention provides a material for intraocular lens which has improved hydrolysis resistance. The material for intraocular lens according to the present invention is obtained by polymerizing a monomer composition comprising: a base monomer, a hydrophilic monomer, and a cross-likable monomer, wherein the base monomer comprises an aromatic ring-containing acrylate monomer and an alkoxyalkyl methacrylate monomer having an alkoxyalkyl group having four or less carbon atoms. A blending ratio on a molar basis of the methacrylate monomer with respect to the acrylate monomer in all the monomer components contained in the monomer composition is 0.25 to 1.00.

Abstract: Provided is an immunogenic composition which contains a self-assembling peptide as an adjuvant and can increase the immunogenicity of various antigens. The present invention provides an immunogenic composition including: a peptide hydrogel containing a positively or negatively charged self-assembling peptide and an aqueous medium; and an antigen, in which the self-assembling peptide is not covalently bonded to the antigen.

Abstract: An ocular device case with a new structure that can solve unexpected problems in the related art, for example, adverse effects on user's eyes by splashes of treatment liquid upon pouring the treatment liquid into the device case from a separate refill container. In a device case including: a case body accommodating treatment liquid with ocular devices such as a contact lens; and a lid, a container receiving portion is provided such that a spout of a refill container is brought into contact with the refill receiving portion so as to allow the treatment liquid to flow into the device case.

Abstract: An ophthalmic medical device including a photochromic polymer having higher transparency under an inactive state through use of a photochromic monomer. An ophthalmic medical device according to one embodiment that includes a photochromic polymer obtained by polymerizing monomer components including a photochromic monomer and a lactam ring-containing monomer, wherein a content ratio of the lactam ring-containing monomer in the monomer components is from 10 wt % to 50 wt %. The ophthalmic medical device is typically a contact lens or an intraocular lens.

Abstract: A disinfection system of a contact lens comprising immersing the contact lens in a disinfecting solution containing hydrogen peroxide in a concentration of 1 to 10% and neutralizing the hydrogen peroxide in the disinfecting solution through contact with a metal catalyst, where the disinfecting solution contains an organic carboxylic acid or a salt of the organic carboxylic acid, the organic carboxylic acid having a structure in which a hydroxyl group and a carboxyl group are bonded to one carbon atom; the disinfecting solution is adjusted to have a pH of 6 to 8; and the disinfecting solution after the neutralization is adjusted to have an osmotic pressure of 250 to 350 mOsm.

Abstract: A disinfection system of a contact lens comprising immersing the contact lens in a disinfecting solution containing hydrogen peroxide in a concentration of 1 to 10% and neutralizing the hydrogen peroxide in the disinfecting solution through contact with a metal catalyst, where the disinfecting solution contains an organic carboxylic acid or a salt of the organic carboxylic acid, the organic carboxylic acid having a structure in which a hydroxyl group and a carboxyl group are bonded to one carbon atom; the disinfecting solution is adjusted to have a pH of 6 to 8; and the disinfecting solution after the neutralization is adjusted to have an osmotic pressure of 250 to 350 mOsm.

Abstract: A nail cosmetic composition contains a silicone macromonomer as a base material having at least two polymerizable functional groups and a polymerization initiator with respect to the silicone macromonomer. A method of using a nail cosmetic composition includes a painting step of painting a nail cosmetic composition described above on a nail and a curing step of exposing the nail cosmetic composition to light with an illuminance of 80 mW/cm2 or less at dominant wavelength at an exposure time within three minutes per one layer to cure the nail cosmetic composition. The nail cosmetic resin contains a silicone unit in which a silicone macromonomer has been polymerized as the base material having at least two polymerizable functional groups.

Abstract: A contact lens package includes a silicone hydrogel contact lens, a packaging container composed of a polypropylene, and a packaging solution containing a nonionic surfactant, the nonionic surfactant including a linear alkyl moiety having 12 or more carbon atoms and an oxyethylene moiety, the average addition mole number of oxyethylene being 30 or more per mole of the nonionic surfactant.

Abstract: A silicone-containing polymer material containing an internal wetting agent and being excellent in transparency, the silicone-containing polymer material being improved in antifouling property against lipids. The polymer material of the present invention is a polymer material, which is obtained by polymerizing a polymerizable mixture containing monomer components (a) and a hydrophilic polymer component (b), wherein the monomer components (a) include a silicone-containing monomer (a-1) having a siloxane bond and being free of any hydroxyl group, and a compatibilizing monomer (a-2) having a hydrogen bonding proton-containing group and being free of any silicon atom, and wherein the compatibilizing monomer has four or more carbon atoms, excluding carbon atoms contained in a polymerizable functional group, and has a solubility of less than 0.03 g/mL in water at 25° C.

Abstract: Provided is an ophthalmic diffractive multi-focal lens with a diffractive structure including a phase profile in which a plurality of blaze shaped zones are set in a concentric circle form, wherein: at least one of the zones serves as an adjustment zone wherein an inclination direction in the phase profile is reversed with respect to that of other zones; and a light intensity level giving a peak or focal point at a position away from three focal points in a light intensity distribution of transmitted light in an optical axis direction is kept low in comparison with a phase profile without the adjustment zone.

Abstract: The present invention provides a material for intraocular lens which has improved hydrolysis resistance. The material for intraocular lens according to the present invention is obtained by polymerizing a monomer composition comprising: a base monomer, a hydrophilic monomer, and a cross-likable monomer, wherein the base monomer comprises an aromatic ring-containing acrylate monomer and an alkoxyalkyl methacrylate monomer having an alkoxyalkyl group having four or less carbon atoms. A blending ratio on a molar basis of the methacrylate monomer with respect to the acrylate monomer in all the monomer components contained in the monomer composition is 0.25 to 1.00.

Abstract: Provided is an immunogenic composition which contains a self-assembling peptide as an adjuvant and can increase the immunogenicity of various antigens. The present invention provides an immunogenic composition including: a peptide hydrogel containing a positively or negatively charged self-assembling peptide and an aqueous medium; and an antigen, in which the self-assembling peptide is not covalently bonded to the antigen.

Abstract: The present invention provides a bone formation promoter having high biological safety and capable of promoting bone formation. The bone formation promoter of the present invention includes a self-assembling peptide capable of forming a ?-sheet structure in an aqueous solution having a neutral pH; and a bone chip. A sum of charges of amino acid residues constituting the self-assembling peptide at pH 7.0 is unequal to 0.

Abstract: A disinfection system of a contact lens comprising immersing the contact lens in a disinfecting solution containing hydrogen peroxide in a concentration of 1 to 10% and neutralizing the hydrogen peroxide in the disinfecting solution through contact with a metal catalyst, where the disinfecting solution contains an organic carboxylic acid or a salt of the organic carboxylic acid, the organic carboxylic acid having a structure in which a hydroxyl group and a carboxyl group are bonded to one carbon atom; the disinfecting solution is adjusted to have a pH of 6 to 8; and the disinfecting solution after the neutralization is adjusted to have an osmotic pressure of 250 to 350 mOsm.

Abstract: A diffractive multi-focal lens having a diffractive structure comprising a plurality of concentric circular zones, wherein: at least a portion of the diffractive structure is provided with an overlapping region in which at least two zone profiles overlap in the same region; in the overlapping region, at least a portion of a first zone profile has a zone pitch represented by a prescribed equation, and at least a portion of a second zone profile has a zone pitch represented by another prescribed equation; and an addition power P1 given by the first zone profile and an addition power P2 given by the second zone profile are determined by a prescribed relational expression, in which a and b are mutually different real numbers, and a value of a/b cannot be expressed by a natural number X or by 1/X.