Abstract: Provide are a peptide gel with practically sufficient mechanical strength and a self-assembling peptide capable of forming the peptide gel. The self-assembling peptide is formed of the following amino acid sequence: a1b1c1b2a2b3 db4a3b5c2b6a4 where: a1 to a4 each represent a basic amino acid residue; b1 to b6 each represent an uncharged polar amino acid residue and/or a hydrophobic amino acid residue, provided that at least five thereof each represent a hydrophobic amino acid residue; c1 and c2 each represent an acidic amino acid residue; and d represents a hydrophobic amino acid residue.

Abstract: In order to reduce halos that occur in multifocal ophthalmic lenses, the mechanism of the phenomenon was elucidated and a solution was found based on the results. Thus provided are a multifocal ophthalmic lens having a structure and a manufacturing method for the same which can effectively reduce halos. A multifocal ophthalmic lens having a focal point formation region provided to an optical portion of a lens, which forms at least two focal points, wherein a cancellation region is provided to the optical portion, the cancellation region providing diffracted light of an amplitude distribution that reduces, on the image plane of the first focal point among the focal points, the amplitudes of light other than the light that forms the first focal point.

Abstract: The present invention provides a dye composition for an ophthalmic lens, which is a dye composition used for dyeing an ophthalmic lens with an ink-jet coating equipment, characterized by the composition including: (A) a dye having at least one group having a carbon-carbon double bond selected from an ?,?-unsaturated carbonyl group, a styryl group, a vinylbenzyl group and an allyl group per molecule; (B) a radical polymerization initiator; and (C) a solvent capable of dissolving at least a part of the component (A) and the component (B), and/or (D) a monomer having at least one radical polymerizable group per molecule.

Abstract: Provided is a diffraction-type multifocal ophthalmic lens for which halos are reduced. Also provided is a diffraction-type multifocal ophthalmic lens having three or more focal points, which is implemented on the basis of the discovery that the diffraction-type multifocal ophthalmic lens has a characteristic whereby multiple focal points can be generated in the intermediate region as well as the near and far regions. Also provided is a method for manufacturing a diffraction-type multifocal ophthalmic lens which provides a simple design and manufacturing method by means of a simple diffraction structure and by replacing a cumbersome computer simulation with a simple method. This diffraction-type multifocal ophthalmic lens has a diffraction structure (20) where a plurality of diffraction zones are formed concentrically on the lens (10), and an equal-pitch region is provided where pitches of at least two zones among the diffraction zones are made equal.

Abstract: Provided is a colored contact lens in which a colored band is disposed at a boundary part between a dark part and a white part of an eye, and a density is gradually changed from the dark part to the white part of the eye such that the density of this colored band decreases from an inner circumference side to an outer circumference side. As a result, a novel colored contact lens is provided with which it is possible to bring out beauty of the white part of the eye, which has been ignored by conventional technology, while an impression is maintained that is as natural and elegant as possible by avoiding an artificial impression such as that found in conventional technology.

Abstract: Provide are a peptide gel with practically sufficient mechanical strength and a self-assembling peptide capable of forming the peptide gel. The self-assembling peptide is formed of the following amino acid sequence: a1b1c1b2a2b3 db4a3b5c2b6a4 where: a1 to a4 each represent a basic amino acid residue; b1 to b6 each represent an uncharged polar amino acid residue and/or a hydrophobic amino acid residue, provided that at least five thereof each represent a hydrophobic amino acid residue; c1 and c2 each represent an acidic amino acid residue; and d represents a hydrophobic amino acid residue.

Abstract: Disclosed is an implementation of new technology for effectively providing a contact lens capable of achieving satisfactory corrective effects even with respect to irregular astigmatism (residual irregular astigmatism) caused by a conical cornea and so forth, which could not be corrected with conventional eye glasses or contact lens, wherein the contact lens is not dependent on being made to order for each wearer but is industrially mass-producible by means of a practical and novel structure. A contact lens for correction of irregular astigmatism is disclosed wherein a positive correction area (27) is provided on one side of a special radial line (30) and a negative correction area (28) is provided on another side while in any of the correction areas (27, 28) a lens power is configured so that an absolute value becomes progressively larger from an outer peripheral edge part towards a central portion.

Abstract: The present invention relates to water soluble quaternized chitosan derivatives which form hydrogel matrix with broad antimicrobial properties for the protection and coating of medical device. Hydrogel is attractive as an antimicrobial coating since its hydrophilicity intrinsically prevents the reversible nonspecific attachment of microbes. In order to achieve hydrogel formation, quaternized chitosan can be grafted with polymerizable groups, especially photocrosslinkable groups, such as methacrylates, PEG derivatives and be converted into hydrogels through a thermal or UV polymerization process. Hydrogels are hydrated cross-linked polymeric systems that contain water in an equilibrium state forming cushion water shield. The present invention is widely used in many medical devices.

Abstract: A novel manufacturing method for a diffraction lens, whereby aperture and eccentricity effects can be suppressed and any multi-focusing effect can also be obtained in a more stable manner. A synchronous structure is set up where at least two reliefs whose first order diffracted lights give respective focal distances different from one another are set to overlap with each other in at least a part of an area in a radial direction of a diffraction lens, and with respect to every grating pitches of one relief having the maximum grating pitch among the reliefs set up in overlap, grating pitches of another relief are overlapped periodically; and the resulting relief pattern is formed on a surface of an optical material.

Abstract: The present invention provides a canine glaucoma-susceptibility gene and a method of using the gene. Single nucleotide polymorphisms were analyzed and compared in glaucomatous dogs and normal dogs. Out of those polymorphic sites at which differences were observed between glaucomatous and normal dogs, two polymorphic sites of the Single Nucleotide Polymorphism Database (dbSNP) ID numbers rs22018513 and rs22018514 were found effective for diagnosis of glaucoma.

Abstract: Provide are a peptide gel with practically sufficient mechanical strength and a self-assembling peptide capable of forming the peptide gel. The self-assembling peptide is formed of the following amino acid sequence: a1b1c1b2a2b3db4a3b5c2b6a4 where: a1 to a4 each represent a basic amino acid residue; b1 to b6 each represent an uncharged polar amino acid residue and/or a hydrophobic amino acid residue, provided that at least five thereof each represent a hydrophobic amino acid residue; c1 and c2 each represent an acidic amino acid residue; and d represents a hydrophobic amino acid residue.

Abstract: A small automatic polishing liquid cleaning device for rigid gas permeable contact lens includes a container; a containing chamber is provided inside the container; an exhaust pipe, and a liquid suction pipe which communicates with the containing chamber disposed on the container; an outlet end of the exhaust pipe communicates with a vacuum orifice of a vacuum generator via a connector, a gas inlet of the vacuum generator communicates with a pipeline for a compressed gas, and a liquid inlet of the liquid suction pipe is disposed at the bottom of a waste liquid trough.

Abstract: A high precision rigid gas-permeable contact lens edge curve polishing lathe includes a base provided at the bottom of a machine body. A first crank and a second crank are respectively provided on two sides of the base. A detent mechanism is provided on both the first crank and the second crank. The detent mechanism includes an ejector pin matching the rotational direction of the first crank and the second crank and a numerical display unit revealing the position of the ejector pin. The contact position of a polishing sponge on a spindle of the polishing lathe and a lens can be precisely positioned through numerical reading, realizing quantized control of the polishing of a lens edge, and enabling improvement and modification to the design of the lens edge to become simpler.

Abstract: The present invention relates to water soluble quaternized chitosan derivatives which form hydrogel matrix with broad antimicrobial properties for the protection and coating of medical device. Hydrogel is attractive as an antimicrobial coating since its hydrophilicity intrinsically prevents the reversible nonspecific attachment of microbes. In order to achieve hydrogel formation, quaternized chitosan can be grafted with polymerizable groups, especially photocrosslinkable groups, such as methacrylates, PEG derivatives and be converted into hydrogels through a thermal or UV polymerization process. Hydrogels are hydrated cross-linked polymeric systems that contain water in an equilibrium state forming cushion water shield. The present invention is widely used in many medical devices.

Abstract: According to the present invention, a contact lens material being excellent in oxygen permeability and transparency, being capable of undergoing injection molding, having no water content and having flexibility is provided. The present invention also relates to a contact lens gel material having excellent oxygen permeability and transparency. Particularly, the present invention relates to a contact lens material comprising a polycarbonate resin derived from a bisphenol compound (A), a polysiloxane-substituted bisphenol compound (B) and a compound forming a carbonic acid ester.

Abstract: A cell culture vessel supplies cells close to the center of gel and deeper down to the bottom with sufficient nutrients for attaining an enhanced survival rate of the cultivated cells. The cell culturing vessel comprises a culture tray capable of holding a liquid culture medium and a cell mixture container fixed to inner walls of the culture tray for retaining the cell mixture. Once the culture tray is filled with the liquid culture medium, the cell mixture retained in the cell mixture container has its opposite outer parts exposed to the liquid culture medium.

Abstract: Providing a system which can exhibit a desired effect of improving hydrophilicity of a contact lens without causing adverse influences on sense of use of the contact lens and a cleaning effect, and which can effectively prevent adhesion of lipid stain. Also providing a packaging solution for the contact lens which can effectively suppress or prevent reduction of its viscosity with time even when the packaging solution is sterilized by heating. The contact lens is immersed in an aqueous solution which contains a low-molecular weight hyaluronic acid having a molecular weight of not higher than 80,000, or a salt or derivative thereof, and which has a pH of 6.0-8.0 and an osmotic pressure of 220-380 mOsm.

Abstract: Provided is a contact lens having a novel structure with a high level of practicality which is easy to manufacture and apply to users, and can improve quality of vision (QOV). In an optical part of a contact lens, a spherical aberration of a size corresponding to a coma aberration of a user's naked eye, and of a size for which a spherical aberration of the user's naked eye will not be offset and will be made to remain is set as a corrective optical characteristic for a residual irregular astigmatism of the user's naked eye. A high-order aberration of the optical part is set rotationally symmetric around an optical axis.

Abstract: The present invention provides a hybrid soft contact lens including a central portion formed with a first hydrous soft material, and a peripheral portion formed with a second hydrous soft material, in which the first hydrous soft material is obtained by curing a first curable composition including a silicone-containing monomer. Preferably, the first hydrous soft material has a Young's modulus of no less than 3.0 MPa and no greater than 100 MPa, and the second hydrous soft material has a Young's modulus of no less than 0.20 MPa and less than 3.0 MPa.

Abstract: The present invention discloses a process for producing a membrane for separating methane or carbon dioxide, having excellent heat resistance, durability and anti-chemical agent resistance (anti-corrosion resistance). The present invention is related to a process for producing a membrane for separating methane or carbon dioxide, which comprises the following steps: (a) preparing a metal alkoxide solution by (i) mixing an acid catalyst, water and an organic solvent, (ii) adding thereto tetraalkoxysilane and mixing, and (iii) then adding thereto a hydrocarbon group-containing trialkoxysilane, of which a hydrocarbon group is selected from the group consisting of an alkyl group having 1 to 6 carbon atoms and a phenyl group, and mixing, (b) applying the metal alkoxide solution on an inorganic porous support, and then (c) calcining the inorganic porous support having metal alkoxide solution layer at a temperature of 30 to 300° C.