Patents Assigned to Merck Patent Gesellschaft Mit Beschraenkter Haftung
  • Patent number: 8278312
    Abstract: Novel compounds of the formula (I), in which W, T, R1, R2, R3, R4, R5, R6 and X7 have the meanings indicated in Patent Claim 1, are suitable as antidiabetics.
    Type: Grant
    Filed: September 13, 2008
    Date of Patent: October 2, 2012
    Assignee: Merck Patent Gesellschaft mit Beschränkter Haftung
    Inventors: Markus Klein, Werner Mederski, Christos Tsaklakidis, Norbert Beier
  • Patent number: 8278394
    Abstract: The invention relates to polymers comprising indenofluorene units or derivatives thereof, organic semiconductor (OSC) materials comprising them, their use in electronic or electrooptical devices, and devices comprising said polymers or materials.
    Type: Grant
    Filed: April 13, 2007
    Date of Patent: October 2, 2012
    Assignee: Merck Patent Gesellschaft mit Beschränkter Haftung
    Inventors: Junyou Pan, Susanne Heun, Frank Meyer
  • Patent number: 8278454
    Abstract: The invention relates to a novel process for preparing enantiomerically enriched or pure tetrahydroquinoline derivatives by reacting a chiral dihydropyran-methylamine C with a aldehyde B and an aniline A in a multicomponent one pot synthesis in the presence of a protonic acid or lewis acid with a suitable solvent. A, B, C have the meaning as described in the specification.
    Type: Grant
    Filed: November 20, 2008
    Date of Patent: October 2, 2012
    Assignee: Merck Patent Gesellschaft mit beschränkter Haftung
    Inventors: Ulrich Emde, Oliver Block, Kai Schiemann
  • Patent number: 8252389
    Abstract: The invention relates to novel mesogenic dimeric compounds which are especially suitable for use in birefringent films with negative optical dispersion, to novel liquid crystal (LC) formulations and polymer films comprising them, and to the use of the dimers, formulations and films in optical, electrooptical, electronic, semiconducting or luminescent components or devices.
    Type: Grant
    Filed: August 29, 2008
    Date of Patent: August 28, 2012
    Assignee: Merck Patent Gesellschaft mit Beschränkter Haftung
    Inventors: Kevin Adlem, Owain Llyr Parri, Karl Skjonnemand, David Wilkes
  • Patent number: 8236824
    Abstract: Novel heterocyclic compounds of the formula I in which R1, R2, R3, R4, R5, R6, R7, Alk and D have the meanings indicated in claim 1, are activators of glucokinase and can be used for the prevention and/or treatment of Diabetes Typ 1 and 2, obesity, neuropathy and/or nephropathy.
    Type: Grant
    Filed: September 9, 2008
    Date of Patent: August 7, 2012
    Assignee: Merck Patent Gesellschaft mit Beschränkter Haftung
    Inventors: Lars Thore Burgdorf, Norbert Beier, Johannes Gleitz, Ulrich Emde, Christine Charon, Denis Carniato
  • Patent number: 8236390
    Abstract: The invention relates to a liquid-crystalline medium based on a mixture of polar compounds, characterized in that it comprises one or more compounds of the formula I in which R1, X1, L1-5 have the meanings indicated in Claim 1, and to the use thereof for electro-optical purposes, in particular TN monitor applications.
    Type: Grant
    Filed: December 17, 2008
    Date of Patent: August 7, 2012
    Assignee: Merck Patent Gesellschaft mit beschränkter Haftung
    Inventors: Harald Hirschmann, Michael Wittek, Sabine Schoen
  • Patent number: 8232272
    Abstract: The present invention relates to novel benzimidazole-dihydrothiadiazinone derivatives as fructose-1,6-bisphosphatase inhibitors, to processes for the preparation thereof and to the use thereof in therapy, especially for the treatment of diabetes.
    Type: Grant
    Filed: October 13, 2008
    Date of Patent: July 31, 2012
    Assignee: Merck Patent Gesellschaft mit beschränkter Haftung
    Inventors: Gerard Botton, Caroline Leriche, Annick Arbellot de Vacqueur, Annick Audet, Johannes Gleitz
  • Patent number: 8231806
    Abstract: The present invention relates to dielectrically positive liquid-crystalline media comprising in each case one or more compounds of the formula I in which the parameters have the respective meanings indicated in the specification, and optionally one or more further dielectrically positive compounds and optionally one or more further dielectrically neutral compounds, and to liquid-crystal displays containing these media, especially to active-matrix displays and in particular to TN, IPS and FFS displays.
    Type: Grant
    Filed: February 25, 2009
    Date of Patent: July 31, 2012
    Assignee: Merck Patent Gesellschaft mit beschränkter Haftung
    Inventors: Markus Czanta, Michael Wittek, Lars Lietzau, Marcus Reuter, Brigitte Schuler
  • Patent number: 8221854
    Abstract: The present invention relates to dielectrically positive liquid-crystalline media comprising a dielectrically positive component, component A, comprising a dielectrically positive compound of the formula I in which the parameters have the meaning indicated in the specification, and optionally a second dielectrically positive component, component B, comprising one or more dielectrically positive compounds having a dielectric anisotropy of great than 3, and optionally a dielectrically neutral component, component C, and to liquid-crystal displays containing these media, especially active-matrix displays and in particular TN, IPS and FFS displays.
    Type: Grant
    Filed: April 1, 2008
    Date of Patent: July 17, 2012
    Assignee: Merck Patent Gesellschaft MIT Beschränkter Haftung
    Inventors: Markus Czanta, Andreas Taugerbeck, Renate Bender, Lars Lietzau
  • Patent number: 8202882
    Abstract: Novel 5-cyanothienopyridines of the formula (I), in which R1, R2 and R3 have the meanings indicated in claim 1, are inhibitors of TGF-beta receptor kinase, and can be employed, inter alia, for the treatment of tumors.
    Type: Grant
    Filed: September 19, 2008
    Date of Patent: June 19, 2012
    Assignee: Merck Patent Gesellschaft MIT Beschränkter Haftung
    Inventors: Guenter Hoelzemann, Ulrich Graedler, Hartmut Greiner, Christiane Amendt, Djordje Musil, Per Hillertz
  • Patent number: 8198452
    Abstract: The invention relates to a process for the manufacture of enantiomerically enriched or pure compounds of formula I wherein R1, R2, R3, R6, R7 and Q are defined as in claim 1 as well as their crystalline forms for the treatment of proliferative diseases such as cancer.
    Type: Grant
    Filed: May 26, 2007
    Date of Patent: June 12, 2012
    Assignee: Merck Patent Gesellschaft MIT Beschränkter Haftung
    Inventors: Kai Schiemann, Ulrich Emde, Tobias Schlueter, Christoph Saal, Michael Maiwald
  • Patent number: 8178556
    Abstract: Described are pyridopyrazinone derivatives of formula (I), wherein X, Y, Z, W, A and R1 are as defined in claim 1, as insulin secretion stimulators. Also described is the preparation and use of these pyridopyrazinone derivatives for the prophylaxis and/or treatment of diabetes and pathologies associated.
    Type: Grant
    Filed: February 27, 2009
    Date of Patent: May 15, 2012
    Assignee: Merck Patent Gesellschaft MIT Beschraenkter Haftung
    Inventors: Gerard Botton, Eric Valeur, Micheline Kergoat, Christine Charon, Samer Elbawab
  • Patent number: 8173653
    Abstract: Compounds of the formula (I), in which R1, R2 and R3 have the meanings indicated in claim 1, are inhibitors of tyrosine kinases, in particular Met kinase, and can be employed, inter alia, for the treatment of tumors.
    Type: Grant
    Filed: November 7, 2006
    Date of Patent: May 8, 2012
    Assignee: Merck Patent Gesellschaft MIT Beschraenkter Haftung
    Inventors: Dieter Dorsch, Oliver Schadt, Andree Blaukat
  • Patent number: 8168083
    Abstract: The present invention relates to an electro-optical light-modulation element of the FFS type, and to electro-optical displays and display systems, such as, for example, television screens and computer monitors, which contain elements of this type. The light-modulation elements according to the invention contain a liquid-crystalline modulation medium which has optimised elastic constants and are distinguished, in particular, by high contrast and/or optimised transmission in addition to good contrast, a low viewing-angle dependence, short response times and low addressing voltages. The present invention likewise relates to the liquid-crystalline modulation media used in the electro-optical light-modulation elements.
    Type: Grant
    Filed: August 26, 2008
    Date of Patent: May 1, 2012
    Assignee: Merck Patent Gesellschaft MIT Beschraenkter Haftung
    Inventors: Mark Goebel, Markus Czanta
  • Patent number: 8163200
    Abstract: The invention relates to liquid-crystalline compounds of the formula I in which R1, R2, A1, A2, A3, A4, Z1, Z2, Z3, V, a, b and c have the meanings indicated in Claim 1, and to liquid-crystalline media comprising at least one compound of the formula I, and to electro-optical displays containing a liquid-crystalline medium of this type.
    Type: Grant
    Filed: July 18, 2007
    Date of Patent: April 24, 2012
    Assignee: Merck Patent Gesellschaft MIT Beschraenkter Haftung
    Inventors: Lars Lietzau, Markus Czanta, Atsutaka Manabe, Kai Jaehrling
  • Patent number: 8148551
    Abstract: The invention relates to tricyclic aromatics of the general formula I in which A1, A2, A3, A4, Q1-Q2, R1, R2, X1, X2, X3, Z1, Z2, Z3, Z4, q, r, s, t and u have the meaning indicated, and to the use thereof as components of liquid-crystalline media and to an electro-optical display element containing same.
    Type: Grant
    Filed: December 29, 2006
    Date of Patent: April 3, 2012
    Assignee: Merck Patent Gesellschaft MIT Beschraenkter Haftung
    Inventors: Rudolf Eidenschink, Holger Kretzschmann
  • Publication number: 20120041165
    Abstract: This invention relates to coloured polymer particles preferably with surface functionality for charge retention, a process for their preparation, the use of these particles for the preparation of an electrophoretic device, colour electrophoretic displays comprising such particle, and new water-soluble dyes.
    Type: Application
    Filed: January 29, 2010
    Publication date: February 16, 2012
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG
    Inventors: Nils Greinert, Louise Diane Farrand, Mark James, Ashley Nathan Smith, Mark John Goulding, Daniel Walker, Safyan Khan, Paul Reynolds, Susan Hawkins, Roy Hughes
  • Publication number: 20110255048
    Abstract: The present invention relates to liquid-crystal (LC) media for use in LC displays of the PS (polymer stabilised) or PSA (polymer sustained alignment) type.
    Type: Application
    Filed: November 26, 2009
    Publication date: October 20, 2011
    Applicant: Merck Patent Gesellschaft MIT Beschraenkter Haftung
    Inventors: Achim Goetz, Melanie Klasen-Memmer, Stepham Derow
  • Publication number: 20110140039
    Abstract: The invention relates to a liquid-crystalline medium containing one or more compounds of the formula I and one or more compounds selected from the group of the compounds of the formula IA to IE in which R0, R1, R2, X1, X2, A1, Z1, m, p, q, v have the meanings indicated in claim 1, and to the use thereof in electro-optical liquid-crystal displays.
    Type: Application
    Filed: July 13, 2009
    Publication date: June 16, 2011
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRÄNKTER HAFTUNG
    Inventors: Mingchou Wu, Martin (Kelun) Shu, Carol (Yi-Hsuan) Lin, Mark Verrall
  • Publication number: 20110136819
    Abstract: Compounds of the formula I, in which R1, R2 and R3 have the meanings indicated in claim 1, are inhibitors of tyrosine kinases, in particular Met kinase, and can be employed, inter alia, for the treatment of tumours.
    Type: Application
    Filed: July 18, 2008
    Publication date: June 9, 2011
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRÄNKTER HAFTUNG
    Inventors: Dieter Dorsch, Oliver Schadt, Andree Blaukat, Frank Stieber