Patents Assigned to Merck Patent Gesellschaft Mit Beschraenkter Haftung
  • THIAZOLYL PIPERIDINE DERIVATIVES
    Publication number: 20110105505
    Abstract: Compounds of the formula (I), in which R1, R2, R3, R4, R5, R6, R9, R10, R11, Q and W have the meanings indicated in Claim 1, and precursors thereof are inhibitors of sphingosine kinase and can be employed, inter alia, for the treatment of tumours.
    Type: Application
    Filed: May 28, 2009
    Publication date: May 5, 2011
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRÄNKTER HAFTUNG
    Inventors: Frank Stieber, Timo Heinrich, Dirk Wienke
  • STABLE CRYSTAL MODIFICATIONS OF DOPC
    Publication number: 20110086091
    Abstract: The invention relates to stable crystal modifications of (R,S)-, (R)- and (5S)-DOPC, to a process for the preparation of these modifications, and to the use thereof as constituent for the preparation of medicaments.
    Type: Application
    Filed: May 13, 2009
    Publication date: April 14, 2011
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRÄNKTER HAFTUNG
    Inventors: Michael Platscher, Alfred Hedinger
  • 1,5-diphenylpyrazoles II as HSP90 inhibitors
    Patent number: 7906657
    Abstract: Novel 1,5-diphenylpyrazole derivatives of the formula (I) in which R1-R6 have the meanings indicated in claim 1, are HSP90 inhibitors and can be used for the preparation of a medicament for the treatment of diseases in which the inhibition, regulation and/or modulation of HSP90 plays a role.
    Type: Grant
    Filed: April 20, 2007
    Date of Patent: March 15, 2011
    Assignee: Merck Patent Gesellschaft MIT Beschraenkter Haftung
    Inventors: Hans-Michael Eggenweiler, Michael Wolf, Hans-Peter Buchstaller, Christian Sirrenberg
  • Use of laser-engraved printing forms
    Patent number: 7891293
    Abstract: The present invention relates to the use of laser-engraved printing forms for printing using printing inks in a gravure printing process, where the printing inks are pigmented with flake-form effect pigments, to a corresponding gravure printing process, and to a printing ink.
    Type: Grant
    Filed: May 3, 2006
    Date of Patent: February 22, 2011
    Assignee: Merck Patent Gesellschaft mit beschraenkter Haftung
    Inventors: Andreas Becker, Thomas Rathschlag, Rüdiger Smolka, Edgar Sudhues
  • AQUEOUS PHARMACEUTICAL COMPOSITION
    Publication number: 20100210681
    Abstract: The present invention relates to an aqueous pharmaceutical composition comprising 1-(2-dimethylaminoethyl)-3-((2R,4aS,5R,10bS)-5-phenyl-9-trifluoromethyl-3,4,4a,5,6,10b-hexahydro-2H-pyrano[3,2-c]quinolin-2-ylmethyl)urea as active compound, to a liquid pharmaceutical composition which is suitable for the preparation of the aqueous pharmaceutical composition, and to a process for the preparation of the compositions.
    Type: Application
    Filed: April 24, 2008
    Publication date: August 19, 2010
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRÄNKTER HAFTUNG
    Inventors: Holger Bauer, Norbert Rasenack, Kerstin Ammer, Bianka Kemmerer, Kirstin Heil
  • LIQUID-CRYSTAL DISPLAY
    Publication number: 20100188618
    Abstract: The present invention relates to a liquid-crystal (LC) display of the PS (polymer stabilised) or PSA (polymer sustained alignment) type, and to polymerisable compounds and LC media for use in PS (polymer stabilised) and PSA displays.
    Type: Application
    Filed: July 3, 2008
    Publication date: July 29, 2010
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRÄNKTER HAFTUNG
    Inventors: Matthias Bremer, Georg Bernatz
  • ARYL ETHER PYRIDAZINONE DERIVATIVES
    Publication number: 20100179149
    Abstract: Compounds of the formula I, in which R1, R2, R3, R4, R5 and X have the meanings indicated in claim 1, are inhibitors of tyrosine kinases, in particular Met kinase, and can be employed, inter alia, for the treatment of tumours.
    Type: Application
    Filed: May 2, 2008
    Publication date: July 15, 2010
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRÄNKTER HAFTUNG
    Inventors: Frank Stieber, Oliver Schadt, Dieter Dorsch, Andree Blaukat
  • Liquid-crystalline medium
    Patent number: 7662443
    Abstract: The invention relates to a liquid-crystalline medium comprising at least one compound of the formula I in which Z1, Z2, Z3, a, b and c are as defined in claim 1, and to electro-optical displays containing a liquid-crystalline medium of this type.
    Type: Grant
    Filed: November 23, 2007
    Date of Patent: February 16, 2010
    Assignee: Merck Patent Gesellschaft mit Beschraenkter Haftung
    Inventors: Michael Heckmeier, Brigitte Schuler, Martin Engel, Peer Kirsch, Matthias Bremer
  • Acidic quinoline derivatives and their use for the prevention and/or treatment of hyperglycaemia-related pathologies
    Patent number: 7470708
    Abstract: The invention relates to compounds of the general formula (I): in which R1, R2, X, and A are as defined in claim 1. These compounds can be used in the treatment of hyperglycaemia-related pathologies.
    Type: Grant
    Filed: December 1, 2004
    Date of Patent: December 30, 2008
    Assignee: Merck Patent Gesellschaft mit Beschraenkter Haftung
    Inventors: Gérard Moinet, Jean-Claude Correc, Annick Arbellot De Vacueur
  • Polymerisable monocyclic compounds
    Patent number: 7465479
    Abstract: The invention relates to polymerisable monocyclic compounds, their use in liquid crystal mixtures, polymers and polymer films, and the use of the compounds, mixtures, polymers and polymer films in optical, electrooptical and electronic devices, for decorative and security applications.
    Type: Grant
    Filed: December 23, 2002
    Date of Patent: December 16, 2008
    Assignee: Merck Patent Gesellschaft Mit Beschraenkter Haftung
    Inventors: Matthias Bremer, Melanie Klasen-Memmer, Dagmar Klement, Stephan Derow
  • Galenical formulation
    Patent number: 7345090
    Abstract: The invention relates to compounds of the formula I where R1, R2, R3, R4 and R5 have the meanings given in claim 1. The compound is suitable in particular for use in skin care compositions. They protect, firstly, against harmful oxidation reactions and, secondly, also act as UV filters.
    Type: Grant
    Filed: April 28, 2004
    Date of Patent: March 18, 2008
    Assignee: Merck Patent Gesellschaft mit Beschraenkter Haftung
    Inventors: Frank Pfluecker, Joachim Buenger, Hans-Juergen Driller, Herwig Buchholz, Ralf Rosskopf
  • Laser-markable plastics and their preparation and use
    Patent number: 7217745
    Abstract: The invention relates to a laser-markable transparent or translucent plastics which comprise pearlescent pigments in combination with laser-sensitive pigments which themselves do not exhibit any pearlescent effect. The pigment combination considerably improves the scanner legibility of applied laser markings. The invention also relates to a process for preparing the plastics, to the use of the plastics for producing moldings, to moldings produced in this way, and generally to the use of a mixture made from pearlescent pigment and laser-sensitive pigment in laser-markable plastics, for improving the scanner legibility of laser markings applied to the plastics.
    Type: Grant
    Filed: December 18, 2001
    Date of Patent: May 15, 2007
    Assignee: Merck Patent Gesellschaft Mit Beschraenkter Haftung
    Inventor: Gerhard Edler
  • Polymerizable liquid crystal material
    Patent number: 7029728
    Abstract: The invention relates to a polymerizable liquid crystal material containing at least one polymerizable surface-active compound, its use for the preparation of anisotropic polymer films, and the use of the liquid crystal material and the polymer films in optical and electrooptical devices, and for decorative and security applications.
    Type: Grant
    Filed: May 1, 2002
    Date of Patent: April 18, 2006
    Assignee: Merck Patent Gesellschaft mit beschraenkter Haftung
    Inventors: Christopher J. Dunn, Simon Greenfield, Richard Harding, Ian Victor Edward Hassall, Alison Linda May, Julian Frederick Samuel Vaughan-Spickers
  • Photoisomerizable compounds
    Patent number: 6849203
    Abstract: The invention relates to photoisomerizable compounds of formula I wherein A, Z, L, R, R1, k, m and r are defined herein.
    Type: Grant
    Filed: April 5, 2002
    Date of Patent: February 1, 2005
    Assignee: Merck Patent Gesellschaft Mit Beschraenkter Haftung
    Inventors: Louise Diane Farrand, Christopher Worrall, Owain Llyr Parri
  • Packaging system for cosmetic formulations
    Patent number: 6817753
    Abstract: The invention relates to a packaging system for the in-situ preparation of cosmetic formulations which has a micromixer. This micromixer can be connected to one or more stock chambers.
    Type: Grant
    Filed: May 23, 2002
    Date of Patent: November 16, 2004
    Assignee: Merck Patent Gesellschaft MIT Beschraenkter Haftung
    Inventors: Joachim Buenger, Hansjürgen Driller, Jutta Zur Lange, Annette Wagner
  • Chromanone derivatives
    Patent number: 6812353
    Abstract: Chromanone derivatives of the formula I in which R1 to R4 are each, independently of one another, H, A, CN, Hal, OR5, COOR5, CF3, OCF3, NO2, Ar, OAr, N(R5)2 or CON(R5)2, R5 is H or A, A is alkyl having 1 to 6 carbon atoms, Ar is phenyl which is unsubstituted or substituted by A, OR5, CN, Hal, CF3, OCF3, NO2 or N(R5)2, Hal is F, Cl, Br or I, and their salts, are suitable as intermediates in the synthesis of medicaments.
    Type: Grant
    Filed: July 29, 2003
    Date of Patent: November 2, 2004
    Assignee: Merck Patent Gesellschaft mit beschränkter Haftung
    Inventors: Heinz-Hermann Bokel, Christoph Muermann, Uschi Schmid-Grossmann
  • Compositions for the treatment of inflammatory joint diseases and osteoporosis
    Patent number: 6812215
    Abstract: Compositions and pharmaceutical compositions are described which comprise: a component A comprising one or more flavonol glycosides, a component B comprising one or more tetrahydrofolic acid compounds, a component C comprising one or more calcium supplements, and a component D comprising one or more magnesium supplements. Methods of using such compositions and pharmaceutical compositions to treat and/or prevent osteoporosis and/or an inflammatory joint disease are also described.
    Type: Grant
    Filed: December 2, 2002
    Date of Patent: November 2, 2004
    Assignee: Merck Patent Gesellschaft mit beschränkter Haftung
    Inventors: Herwig Buchholz, Jerzy Meduski
  • Fluoroalkylphosphate salt electrolytes
    Patent number: 6794083
    Abstract: The present invention relates to mixtures of fluoroalkylphosphate salts and polymers, methods of producing same, and their use in electrolytes, batteries, capacitors, supercapacitors and galvanic cells.
    Type: Grant
    Filed: November 9, 2001
    Date of Patent: September 21, 2004
    Assignee: Merck Patent Gesellschaft mit beschränkter Haftung
    Inventors: Michael Schmidt, Frank Ott, Michael Jungnitz, Nikolai Ignatyev, Andreas Kuehner
  • Thienopyrimidines as phosphodiesterase inhibitors
    Patent number: 6787548
    Abstract: Thienopyrimidines of the formula I and their physiologically acceptable salts, in which R1, R2 and X have the meanings indicated in claim 1, exhibit phosphodiesterase V inhibition and can be employed for the treatment of disorders of the cardiovascular system and for the treatment and/or therapy of potency disorders.
    Type: Grant
    Filed: May 10, 2002
    Date of Patent: September 7, 2004
    Assignee: Merck Patent Gesellschaft mit beschränkter Haftung
    Inventors: Rochus Jonas, Pierre Schelling, Franz-Werner Kluxen, Maria Christadler
  • Electro-optical liquid-crystal display
    Patent number: 6749907
    Abstract: An electro-optical liquid-crystal display having a realignment layer for realigning the liquid crystals whose field has a component, which is crucial for the realignment, parallel to the liquid-crystal layer, containing a liquid-crystalline medium of positive dielectric anisotropy, where the medium comprises at least one mesogenic compound and at least one compound of the formula I in which the substituents are as defined herein.
    Type: Grant
    Filed: March 29, 2001
    Date of Patent: June 15, 2004
    Assignee: Merck Patent Gesellschaft Mit Beschränkter Haftung
    Inventors: Michael Heckmeier, Marcus Reuter, Matthias Bremer, Eike Poetsch