Patents Assigned to Merck Patent Gesellschaft Mit
  • Patent number: 4886620
    Abstract: The invention relates to the use of compounds of the formula IR.sup.1 --Q.sup.1 --A--(A.sup.2).sub.q --R.sup.2 Iwherein ##STR1## and R.sup.1, R.sup.2, Q.sup.1, Q.sup.2 and q have the meaning specified in claim 1, as components of smectic liquid-crystalline phases, and also smectic liquid-crystalline phases, in particular chiral tilted smectic phases containing compounds of formula I.
    Type: Grant
    Filed: May 13, 1987
    Date of Patent: December 12, 1989
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Reinhard Hopf, Bernhard Scheuble, Andreas Wachtler, Reinhard Hittich, Rudolf Eidenschink, Thomas Geelhaar, Joachim Krause, Volker Reiffenrath
  • Patent number: 4885281
    Abstract: The invention relates to formulations in the form of suspensions containing sucralfate, characterized in that they contain, based on the sucralfate, 1-5% by weight of xanthan gum and 1-12.5% by weight of at least one peptiser.
    Type: Grant
    Filed: March 21, 1988
    Date of Patent: December 5, 1989
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Ullrich Hanstein, Lothar Bauer
  • Patent number: 4885372
    Abstract: New cyclopentane derivatives of the formula I ##STR1## in which R.sup.1 is H or a hydroxyl protective group, andR.sup.2 and R.sup.3 are together an O atom or are together a bond, can be used in the preparation of prostaglandin derivatives.
    Type: Grant
    Filed: September 19, 1986
    Date of Patent: December 5, 1989
    Assignee: Merck Patent Gesellschaft mit Beschrankter Haftung
    Inventors: Bernhard Riefling, Hans Witzel
  • Patent number: 4882082
    Abstract: Nitrogen-containing heterocyclic compounds of the formula IR.sup.1 --A.sup.1 --Z.sup.1 --A.sup.2 [Z.sup.2 --A.sup.3 ].sub.n --R.sup.2whereinR.sup.1 and R.sup.2 in each case independently of one another are an alkyl group with 1-15 C atoms, it also being possible for one or two non-adjacent CH.sub.2 groups to be replaced by 0 atoms and/or --CO-- groups and/or --O--CO-- groups and/or --CO--O-- groups, and one of the radicals R.sup.1 and R.sup.2 is also H, F, Cl, Br or CN,is a 1,4-cyclohexylene group, it also being possible for one or two non-adjacent CH.sub.2 groups to be replaced by 0 atoms, a 1,4-bicyclo(2,2,2)-octylene group or a 1,3-dithiane-2,5-diyl group,Z.sup.1 and Z.sup.2 in each case independently of one another are --CO--O--, --O--CO--, --CH.sub.2 CH.sub.2 --, --OCH.sub.2 --, --CH.sub.2 O-- or a single bond,A.sup.2 and A.sup.3 in each case independently of one another are a 1,4-phenylene group, pyrimidine-2,5-diyl group, 1,4-cyclohexylene group, it also being possible for one or two non-adjacent CH.
    Type: Grant
    Filed: March 23, 1988
    Date of Patent: November 21, 1989
    Assignee: Merck Patent Gesellschaft Mit Beschrankter Haftung
    Inventors: Rudolf Eidenschink, Joachim Krause, Reinhard Hittich, Eike Poetsch, Bernhard Scheuble, Georg Weber, Ludwig Pohl
  • Patent number: 4882048
    Abstract: Absorbents based on optically active poly(meth)acrylamides, e.g. bonded to silica gel, can be used for separating racemic mixtures into their optical antipodes.
    Type: Grant
    Filed: February 21, 1989
    Date of Patent: November 21, 1989
    Assignee: Merck Patent Gesellschaft Mit Beschrankter Haftung
    Inventors: Gottfried Blaschke, Werner Fraenkel, Werner Broker, Joachim Kinkel
  • Patent number: 4880492
    Abstract: In a process for the production of thin films and epitaxial layers by gas-phase deposition, intramolecularly stabilized organometallic compounds are employed as a source of metal.
    Type: Grant
    Filed: September 15, 1987
    Date of Patent: November 14, 1989
    Assignee: Merck Patent Gesellschaft Mit Beschrankter Haftung
    Inventors: Dietrich Erdmann, Max E. Van Ghemen, Ludwig Pohl, Herbert Schumann, Uwe Hartmann, Wilfried Wassermann, Meino Heyen, Holger Jurgensen
  • Patent number: 4877220
    Abstract: Hexasubstituted cyclohexane compounds of the formula I ##STR1## in which Z.sup.1, Z.sup.2, Z.sup.3, X.sup.1, X.sup.2, A.sup.1, A.sup.2 and A.sup.3, p, R.sup.1 and R.sup.2, m and (n+m) have the meanings given in claim 1, are suitable as components of discotic liquid-crystalline phases.
    Type: Grant
    Filed: September 11, 1987
    Date of Patent: October 31, 1989
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Klaus Praefcke, Bernd Kohne, Werner Stephan
  • Patent number: 4877547
    Abstract: The invention relates to a new liquid crystal display element with static or multiplex control with a low multiplex ratio and an operating voltage below 3.3 volts, containing a liquid crystal dielectric, wherein the operating temperature range extends from -30.degree. C. to +80.degree. C. and the viscosity of the dielectric at 20.degree. C. is less than 40 mPa.s.
    Type: Grant
    Filed: October 23, 1987
    Date of Patent: October 31, 1989
    Assignee: Merck Patent Gesellschaft mit Beschrankter Haftung
    Inventors: Georg Weber, Bernhard Scheuble, Joachim Krause
  • Patent number: 4877882
    Abstract: D-(+)-Biotin can be prepared from optically active hydantoins of the formula I ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, X and Y have the meaning given in patent claim 1, in a simple, stereospecific manner.Furthermore bicyclic nitriles of the formula XI ##STR2## wherein R.sup.1, R.sup.2, R.sup.3, X and Y have the meaning given represent precious intermediate products and educts of a multitude of possibilities to synthesize optically active D-(+)-biotin.
    Type: Grant
    Filed: October 5, 1988
    Date of Patent: October 31, 1989
    Assignee: Merck Patent Gesellschaft mit Beschrankter Haftung
    Inventors: Eike Poetsch, Michael Casutt
  • Patent number: 4874709
    Abstract: The invention relates to a solvent for the Karl-Fischer determination of water and to a process for the determination of water using a solvent system which contains at least one higher alcohol as well as the customary Karl-Fischer solvents.
    Type: Grant
    Filed: July 12, 1988
    Date of Patent: October 17, 1989
    Assignee: Merck Patent Gesellschaft mit Beschrankter Haftung
    Inventors: Wolfgang Fischer, Karl D. Krenn
  • Patent number: 4873019
    Abstract: 1,3-Cyclopentylene compounds of the formula IR.sup.1 -A.sup.1 -Z.sup.1 -A.sup.2 --(Z.sup.2 -A.sup.3).sub.n -R.sup.2 Iin which R.sup.1, R.sup.2, A.sup.1, A.sup.2, A.sup.3, Z.sup.1, Z.sup.2 and n have the meaning given herein, can be used as components of liquid-crystalline phases.
    Type: Grant
    Filed: December 18, 1987
    Date of Patent: October 10, 1989
    Assignee: Merck Patent Gesellschaft mit Beschrankter Haftung
    Inventors: Joachim Krause, Andreas Wachtler, Bernard Scheuble, Georg Weber
  • Patent number: 4871472
    Abstract: Compounds of the formula I ##STR1## wherein R.sup.1 and R.sup.2 each independently of one another are R, OR, OCOR, COOR or OCOOR,is alkyl with 1 to 15 C atoms, wherein one or more CH.sub.2 groups which are not adjacent and are not linked by O can also be replaced by --O--, --CO--, --O--CO--, --CO--O--, --CH--halogen, --CHCN-- and/or --CH.dbd.CH--,A.sup.1, A.sup.2 and A.sup.3 each independently of one another are 1,4-phenylene or trans-1,4-cyclohexylene,m, n and o are each 0 or 1,m+n+o is 0, 1 or 2,Z.sup.1 and Z.sup.2 each independently of one another are --CH.sub.2 --O--, --OCH.sub.2 --, --CH.sub.2 CH.sub.2 -- or a single bond andX is F, Cl, Br, I or CN,with the provisos given in claim 1, can be used as components of ferroelectric liquid crystal phases.
    Type: Grant
    Filed: October 9, 1987
    Date of Patent: October 3, 1989
    Assignee: Merck Patent Gesellschaft mit Beschrankter Haftung
    Inventors: Joachim Krause, Volker Reiffenrath, Thomas Geelhaar
  • Patent number: 4871470
    Abstract: Cyclohexane derivatives of formula I ##STR1## wherein R is an alkyl group which has 1-12 C atoms and in which one or two non-adjacent CH.sub.2 groups can also be replaced by O, --CO--O-- or --OCO--,A.sup.1 and A.sup.2 each independently of one another are trans-1,4-cyclohexylene or unsubstituted or fluorine-substituted 1,4-phenylene, and one of the groups A.sup.1 and A.sup.2 can also be a single bond,X is --CN, halogen, OH, --COOR.sup.1, --OOCR.sup.1, --COR.sup.1, --OR.sup.1 or R.sup.1 andR.sup.1 is an alkyl group which has 1-12 C atoms and in which one or two CH.sub.2 groups can also be replaced by O, but excluding direct links between two O atoms,with the proviso that, in the case of X=CN, A.sup.2 is trans-1,4-cyclohexylene or fluorine-substituted, 1,4-phenylene, are suitable as components of liquid-crystalline phases.
    Type: Grant
    Filed: October 30, 1987
    Date of Patent: October 3, 1989
    Assignee: Merck Patent Gesellschaft mit Beschrankter Haftung
    Inventors: Andreas Wachtler, Joachim Krause, Rudolf Eidenschink, Georg Weber
  • Patent number: 4869906
    Abstract: A resorbable porous tricalcium phosphate, in which the pores are sealed with a filler mixture of an antibiotic and a filler, in particular an amino acid, is particularly advantageous for use in the preparation of bone cements.
    Type: Grant
    Filed: April 17, 1987
    Date of Patent: September 26, 1989
    Assignee: Merck Patent Gesellschaft Mit Beschrankter Haftung
    Inventors: Elvira Dingeldein, Helmut Wahlig, Manfred Wotschokowsky, Gu Moddelmog
  • Patent number: 4870087
    Abstract: Indole derivatives of the general formula I ##STR1## in which Ind is a 3-indolyl radical which can be substituted once or twice by alkyl, O-alky, S-alkyl, SO-alkyl, SO.sub.2 -alkyl, OH, F, Cl, Br, CF.sub.3 and/or CN or by a methylenedioxy group, A is --(CH.sub.2).sub.4 -- or --CH.sub.2 --L--CH.sub.2 CH.sub.2 --, L is --S--, --SO-- or --SO.sub.2 --, and Th is a 2-- or 3-thienyl radical, and in which the alkyl groups each have 1-4 C atoms, and their physiologically acceptable acid addition salts exhibit effects on the central nervous system.
    Type: Grant
    Filed: March 12, 1984
    Date of Patent: September 26, 1989
    Assignee: Merck Patent Gesellschaft Mit Beschrankter Haftung
    Inventors: Rudolf Gottschlich, Henning Bottcher, Hans-Heinrich Hausberg, Klaus-Otto Minck, Christoph Seyfried
  • Patent number: 4868237
    Abstract: The invention relates to a bone cement based on physiologically tolerated polymers, the incorporation of acoustic perturbation elements having a sound resistance differing from that of the polymer making it possible, in the case of a necessary re-operation, to disrupt the bone cement by the application of acoustic waves to such an extent that it can easily be removed from the implant location.
    Type: Grant
    Filed: June 27, 1986
    Date of Patent: September 19, 1989
    Assignee: Merck Patent Gesellschaft mit Beschrankter Haftung
    Inventors: Gunter Hoff, Jochen Ohnsorge
  • Patent number: 4867793
    Abstract: Platelet-shaped colored pigments in which a platelet-shaped substrate is provided with a compact coating containing iron(II) oxide, which coating has a high gloss and, depending on the layer thickness, shows the interference color of thin platelets, are described.
    Type: Grant
    Filed: May 22, 1987
    Date of Patent: September 19, 1989
    Assignee: Merck Patent Gesellschaft mit Beschrankter Haftung
    Inventors: Klaus D. Franz, Kalus Ambrosius, August Kanpp, Hans D. Brucker
  • Patent number: 4867794
    Abstract: In mica/titanium dioxide pigments reliable rutilization is obtained with small amounts of tin by precipitating tin dioxide directly on the mica and completing this precipitation before the precipitation of titanium dioxide is started.
    Type: Grant
    Filed: December 11, 1987
    Date of Patent: September 19, 1989
    Assignee: Merck Patent Gesellschaft Mit Beschrankter Haftung
    Inventors: Klaus Ambrosius, August Knapp, Helmut Plamper, Reiner Esselborn
  • Patent number: 4867904
    Abstract: Bicyclooctane derivatives of the Formula I ##STR1## wherein R.sup.1, R.sup.2, A.sup.1, A.sup.2 and Z have the meanings indicated in claim 1, are suitable for use as components of liquid-crystal phases for field effect and/or bistability effect displays.
    Type: Grant
    Filed: April 23, 1987
    Date of Patent: September 19, 1989
    Assignee: Merck Patent Gesellschaft mit Beschrankter Haftung
    Inventors: Joachim Krause, Volker Reiffenrath, Bernhard Scheuble, Georg Weber
  • Patent number: 4868341
    Abstract: New bicyclohexyls of the formula IR.sup.1 --Cy--Cy--R.sup.2wherein R.sup.1 and R.sup.2 are each alkyl which has 1-10 C atoms and in which one or two CH.sub.2 group(s) can be replaced by 0 atoms, and Cy is 1,4-cyclohexylene,are suitable for use as the coponents of liquid-crystal dielectrics.
    Type: Grant
    Filed: September 15, 1986
    Date of Patent: September 19, 1989
    Assignees: Merck Patent Gesellschaft Mit Beschrankter Haftung, The Secretary of State for Defence in Her Majesty's Government of the United Kingdom of Great Britain and Northern Ireland
    Inventors: Rudolf Eidenschink, Michael Romer, Georg Weber, George W. Gray, Kenneth J. Toyne