Abstract: Compounds of the formula I in which R1, R4, R6, R, X1, X2, X3, X4, q and W have the meanings indicated in claim 1, are inhibitors of fatty acid synthase, and can be employed, inter alia, for the treatment of diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation.
Type:
Application
Filed:
May 9, 2014
Publication date:
May 12, 2016
Applicant:
Merck Patent GmbH
Inventors:
Christos TSAKLAKIDIS, Wolfgang STAEHLE, Birgitta LEUTHNER, Paul CZODROWSKI, Thomas FUCHSS
Abstract: The invention relates to a method for producing alkali metal salts having monohydrido-tricyanoborate anions from alkali metal monofluorotricyanoborates, and to a method for producing alkali metal salts having dihydrido-dicyanoborate anions from alkali metal difluorodicyanoborates.
Type:
Application
Filed:
June 6, 2014
Publication date:
May 12, 2016
Applicant:
MERCK PATENT GMBH
Inventors:
Nikolai (Mykola) IGNATYEV, Jan Arke Peter SPRENGER, Johannes LANDMANN, Maik FINZE
Abstract: The present invention relates to novel formulations comprising an organic semiconductor (OSC) and one or more organic solvents. The formulation comprises a viscosity at 25° C. of less than 15 mPas and the boiling point of the solvent is at most 400° C. Furthermore, the present invention describes the use of these formulations as inks for the preparation of organic electronic (OE) devices, especially organic photovoltaic (OPV) cells and OLED devices, to methods for preparing OE devices using the novel formulations, and to OE devices, OLED devices and OPV cells prepared from such methods and formulations.
Type:
Application
Filed:
November 20, 2015
Publication date:
May 12, 2016
Applicant:
Merck Patent GmbH
Inventors:
Philip Edward May, Mark James, Piotr Wierzchowiec, Stephen Bain, Paul Craig Brookes, Edgar Kluge, Li Wei Tan, David Sparrowe, Magda Goncalves-Miskiewicz
Abstract: The present invention relates to a compound, comprising a pyrene skeleton and arylamino groups, according to formula (I). The compound is suitable for use as a functional material in electronic devices.
Abstract: Compounds of the formula (I) in which R, R1, R2 and R3 have the meanings indicated in Claim 1, are inhibitors of PDK1 and cell proliferation/cell vitality and can be employed for the treatment of tumors.
Type:
Application
Filed:
January 5, 2016
Publication date:
May 12, 2016
Applicant:
MERCK PATENT GmbH
Inventors:
Dieter DORSCH, Christian SIRRENBERG, Thomas J.J. MUELLER, Eugen MERKUL, Gnuni Amatunu KARAPETYAN
Abstract: The invention relates to a method for producing alkali metal salts having monofluoro-tricyanoborate anions from alkali metal tetrafluoroborates.
Type:
Application
Filed:
June 6, 2014
Publication date:
May 12, 2016
Applicant:
MERCK PATENT GMBH
Inventors:
Nikolai (Mykola) IGNATYEV, Jan Arke Peter SPENGER, Johannes LANDMANN, Maik FINZE
Abstract: The present invention relates to electronic devices, in particular organic electroluminescent devices, comprising compounds of the formula (1), to the corresponding compounds, and to a process for the preparation of these compounds.
Type:
Grant
Filed:
October 11, 2012
Date of Patent:
May 10, 2016
Assignee:
Merck Patent GmbH
Inventors:
Amir Hossain Parham, Christof Pflumm, Anja Jatsch, Thomas Eberle, Philipp Stoessel
Abstract: The present adventure relates to novel compounds of the formula (I) or (II), to the use of the compounds in electronic devices, to a process for the preparation of the compounds, and to electronic devices comprising the compounds, preferably as matrix materials or as electron-transport materials.
Type:
Grant
Filed:
October 20, 2010
Date of Patent:
May 10, 2016
Assignee:
Merck Patent GmbH
Inventors:
Amir Hossain Parham, Christof Pflumm, Arne Buesing, Teresa Mujica-Fernaud, Irina Martynova, Holger Heil, Rémi Manouk Anémian
Abstract: The present invention relates to metal complexes in accordance with formula (1), to use thereof in electronic devices and to electronic devices, particularly organic electroluminescent devices, containing said metal complexes.
Type:
Application
Filed:
February 24, 2014
Publication date:
May 5, 2016
Applicant:
Merck Patent GmbH
Inventors:
Lars Wesemann, Matthias Kleith, Hermann August Mayer
Abstract: The present invention relates to metal complexes and to electronic devices, in particular organic electro-luminescent devices, comprising these metal complexes. M(L)n(L?)m formula (1), where the compound contains a moiety M(L)n of the formula (2).
Type:
Grant
Filed:
June 17, 2011
Date of Patent:
May 3, 2016
Assignee:
Merck Patent GmbH
Inventors:
Philipp Stoessel, Dominik Joosten, Anja Gerhard, Esther Breuning
Abstract: The present invention relates to a method for isolating cells from a complex sample comprising the steps of: a) providing a complex sample, b) incubating said sample with: at least one chaotrope, a buffer and at least one detergent, c) isolating said cells from the resulting mixture by centrifugation or filtration.
Type:
Grant
Filed:
August 10, 2007
Date of Patent:
May 3, 2016
Assignee:
MERCK PATENT GMBH
Inventors:
Peter Rossmanith, Ingeborg Hein, Martin Wagner
Abstract: Embodiments in accordance with the present invention relate generally to the use of polycycloolefinic polymers as a structure defining material in organic electronic devices, and more specifically to separators, insulating structures or bank structures of such devices and to organic electronic devices comprising such structures, to processes for preparing such structures and to organic electronic devices encompassing such structures.
Type:
Grant
Filed:
April 24, 2013
Date of Patent:
May 3, 2016
Assignees:
Merck Patent GmbH, Promerus, LLC
Inventors:
Pawel Miskiewicz, Tomas Backlund, Philip Edward May, Toby Cull, Larry F. Rhodes, Edmund Elce, Andrew Bell
Abstract: An object of the present invention is to provide a filler capable of exhibiting semitransparent foggy effects as in fogged glasses. The present invention provides a filler comprising: a transparent or semitransparent thin platelet-like substrate; a particle layer or coating layer (hereinafter, referred to as a first layer) which is formed on the surface of the thin platelet-like substrate and composed of a hydrous oxide, carbonate, or calcined product thereof, of at least one metal (hereinafter, referred to as a first metal) selected from the group consisting of Mg, Al, and Ca; a coating layer (hereinafter, referred to as a second layer) which coats the thin platelet-like substrate comprising the first layer formed thereon and is composed of an Si hydrous oxide or calcined product thereof; and a coating layer (hereinafter, referred to as a third layer) which coats the second layer and is composed of a Ti hydrous oxide or calcined product thereof.
Abstract: The invention relates to a method for controlling the optical properties of UV filter layers, in particular for controlling the UV absorption properties of metal oxide-containing UV filter layers, to UV filter layers produced thereby, and to the use thereof, in particular for the production of electronic components.
Type:
Application
Filed:
May 28, 2014
Publication date:
April 28, 2016
Applicant:
Merck Patent GmbH
Inventors:
Marc Haeming, Philipp Pacak, Klaus Bonrad
Abstract: The instant invention relates to mesogenic compounds of formula I-Z to mesogenic media, preferably exhibiting a blue phase, comprising a component, component A, consisting of one or more compounds of formula I-Z, and, preferably, a second component, component B, consisting of one or more compounds selected from the group of compounds of formulae I-M and I-U, wherein the parameters are as specified in the text, preferably stabilised by a polymer, and their use in electro-optical light modulation elements and their respective use in displays, as well as to such displays.
Type:
Application
Filed:
March 21, 2014
Publication date:
April 28, 2016
Applicant:
MERCK PATENT GMBH
Inventors:
Michael WITTEK, Matthias BREMER, Andreas TAUGERBECK
Abstract: The compound N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)-3-fluorophenyl)-5-ethyl-1-(pyrimidin-5-yl)-1H-pyrazole-4-carboxamide and pharmaceutically usable salts, tautomers and stereoisomers thereof, including mixtures thereof in all ratios, is an inhibitor of RON and can be employed, for the treatment of cancer.
Type:
Application
Filed:
May 7, 2014
Publication date:
April 28, 2016
Applicant:
Merck Patent GmbH
Inventors:
Oliver SCHADT, Christina ESDAR, Carsten SCHULTZ-FADEMRECHT, Jan EICKHOFF
Abstract: The present invention relates to a conjugate containing at least one kidney-selective carrier molecule and at least one active compound which has a protective action for the kidney against nephrotoxic active compounds, to a process for the preparation of the conjugate, to the use thereof for the protection of the kidney against nephrotoxic active compounds, and to a medicament comprising the conjugate.
Type:
Application
Filed:
April 16, 2014
Publication date:
April 28, 2016
Applicant:
Merck Patent GmbH
Inventors:
Armin KUEBELBECK, Gregor LARBIG, Stefan ARNOLD, Walter MIER, Uwe HABERKORN
Abstract: The invention provides novel heterocyclic amine compounds according to Formula (I) and their manufacture and use for the treatment of hyperproliferative diseases, such as cancer.
Type:
Grant
Filed:
September 12, 2012
Date of Patent:
April 26, 2016
Assignee:
Merck Patent GmbH
Inventors:
Ruoxi Lan, Bayard R. Huck, Xiaoling Chen, Lizbeth Celeste Deselm, Hui Qiu, Yufang Xiao, Constantin Neagu, Igor Mochalkin, Theresa L. Johnson